1-20 of 56
epigenome
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

An integrative model of pathway convergence in genetically heterogeneous blast crisis chronic myeloid leukemia

Tun Kiat Ko, Asif Javed, Kian Leong Lee, Thushangi N. Pathiraja, Xingliang Liu, Simeen Malik, Sheila Xinxuan Soh, Xiu Ting Heng, Naoto Takahashi, Joanna H. J. Tan, Ravi Bhatia, Alexis J. Khng, Wee-Joo Chng, Yee Yen Sia, David A. Fruman, King Pan Ng, Zhu En Chan, Kim Jiajing Xie, Qiangze Hoi, Cheryl Xueli Chan, Audrey S. M. Teo, Oscar Velazquez Camacho, Wee Yang Meah, Chiea Chuen Khor, Chin Thing J. Ong, Wei Jia W. Soon, Patrick Tan, Pauline C. Ng, Charles Chuah, Axel M. Hillmer, S. Tiong Ong
Journal: Blood
Blood (2020) 135 (26): 2337–2353.
https://doi.org/10.1182/blood.2020004834
Published: 2020
Includes: Supplemental data
Journal Articles

Myelodysplastic Syndromes-Associated Gene Mutations Lead to Pseudohypoxia Condition and Epigenome Hyper-Methylation in Mouse Genetic Models

Asumi Yokota, PhD, Lulu Zhang, PhD, Jianhua Feng, Xiaomin Feng, MD PhD, Xiaomei Yan, MD PhD, Gang Huang, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1696.
https://doi.org/10.1182/blood-2019-126799
Published: 2019
Journal Articles

ASXL1 Mutations Are Associated with Widespread and Distinct DNA Methylation Alterations

Nora E Rahmani, MD, Nandini Ramachandra, Tushar D Bhagat, PhD, Shanisha Gordon, Kith Pradhan, PhD, Bianca Rivera Pena, Mohammad Kazemi, Orsi Giricz, PhD, Shahina Maqbool, Raul Olea, Hamid Dolatshad, Vickram Tittrea, Dharamveer Tatwavedi, Shalini Singh, Andrea Pellagatti, Jacqueline Boultwood, Amit Verma, MBBS
Journal: Blood
Blood (2019) 134 (Supplement_1): 2989.
https://doi.org/10.1182/blood-2019-126850
Published: 2019
Journal Articles

The Genome-Wide Impact of Trisomy 21 on DNA Methylation and Its Implications for Hematologic Malignancies

Joseph L. Wiemels, PhD, Ivo S Muskens, Shaobo Li, Priyatama Pandey, Ritu Roy, PhD, Helen M Hansen, BSc, Kimberly D Siegmund, PhD, Beth A Mueller, PhD, Xiaomei Ma, PhD, Catherine Metayer, MD PhD, Adam J de Smith, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2510.
https://doi.org/10.1182/blood-2019-131455
Published: 2019
Journal Articles

Distinct Evolutionary Patterns in Chronic Lymphocytic Leukemia (CLL) during Resistance to Graft-Versus-Leukemia (GvL)

Pavan Bachireddy, MD, Christina Ennis, BA, Vinhkhang N Nguyen, BSc, Nikolas Barkas, PhD, Sachet Shukla, PhD, Kendell Clement, PhD, Samuel Freeman, BSc, Satyen H Gohil, PhD, M.B.,B.S., Natalie Bavli, MD, Liudmila Elagina, PhD, Ignaty Leshchiner, PhD, Jennifer R. Brown, MD PhD, Gad Getz, PhD, Vincent T. Ho, MD, Donna S Neuberg, ScD, Robert J. Soiffer, MD, Jerome Ritz, MD, Edwin P. Alyea, III, MD, Peter Kharchenko, PhD, Catherine J. Wu, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 516.
https://doi.org/10.1182/blood-2019-129520
Published: 2019
Journal Articles

SETDB1 Mediated H3K9 Methylation Suppresses MLL-Fusion Target Expression and Leukemic Transformation

Andrew G. Muntean, PhD, James Ropa, Nirmalya SAHA, PhD MSc, BSc, Hsiang-Yu Hu, BS, Justin Serio, Lili Zhao, Venkatesha Basrur, Alexei Nesvizhskii, Ivan Maillard, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 110.
https://doi.org/10.1182/blood-2019-122610
Published: 2019
Journal Articles

DNMT3A R882 Alters the Epigenome of Hematopoietic Cells

Amanda M Smith, PhD, Taylor LaValle, BS, Shamika Ketkar, PhD, Sai Mukund Ramakrishnan, MS, Christopher A Miller, PhD, Timothy J Ley, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 112.
https://doi.org/10.1182/blood-2019-129003
Published: 2019
Journal Articles

Single Cell Approaches - Drilling Down Deeper Using Technology and Integrated Data Analyses

Dan A. Landau, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): SCI-28.
https://doi.org/10.1182/blood-2019-121046
Published: 2019
Journal Articles

Mir-29 Maintains the Acute Myeloid Leukemia Epigenome By Regulating CBX2

Caryn J. Ha, BA, Wenhuo Hu, PhD, Harold K. Elias, MD, Sohini Chakraborty, PhD, Christopher Y. Park, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1236.
https://doi.org/10.1182/blood-2019-131518
Published: 2019
Journal Articles

Deconvolution of Hematopoietic Commitment Decisions By Genome-Wide Analysis of Progressive DNA Methylation Changes

Sina Staeble, MSc, Stephen Kraemer, MSc, Jens Langstein, MSc, Ruzhica Bogeska, PhD, Mark Hartmann, PhD, Maximilian Schoenung, MSc, Melinda Czeh, PhD, Julia Knoch, Natasha Anstee, PhD, Simon Haas, PhD, Abdelrahman Mahmoud, MSc, Julius Graesel, MSc, Daniel Huebschmann, MD PhD, Lars Feuerbach, PhD, Weichenhan Dieter, PhD, Benedikt Brors, PhD, Karsten Rippe, PhD, Jan-Philipp Mallm, PhD, Frank Rosenbauer, PhD, Christoph Plass, PhD, Matthias Schlesner, PhD, Michael D. Milsom, PhD, Daniel B. Lipka, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1179.
https://doi.org/10.1182/blood-2019-124429
Published: 2019
Journal Articles

Deciphering the Role of Locally Disordered DNA Methylation on CLL Development In Vivo

Anat Biran, PhD, Helene Kretzmer, PhD, Shanye Yin, PhD, Leah Billington, BA, Fara Faye Regis, BS, Arman W. Mohammad, BA, Andreas Gnirke, Donna S Neuberg, ScD, Ruben D. Carrasco, MD PhD, Alexander Meissner, PhD, Catherine J. Wu, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1737.
https://doi.org/10.1182/blood-2019-130744
Published: 2019
Journal Articles

Modeling of the Epigenome of the Cell-of-Origin Identifies Cancer-Specific DNA Methylation Patterns in CLL

Justyna Anna Wierzbinska, Reka Toth, Naveed Ishaque, Jan-Phillip Mallm, Karsten Rippe, Daniel Mertens, Thomas Hielscher, Thorsten Zenz, MD, Marc Seifert, Ralf Küppers, Yassen Assenov, Stephan Stilgenbauer, John C. Byrd, MD, Christopher C. Oakes, Daniel B. Lipka, Christoph Plass
Journal: Blood
Blood (2018) 132 (Supplement 1): 3885.
https://doi.org/10.1182/blood-2018-99-115941
Published: 2018
Journal Articles

Potent and Timed Epigenetic Repression of PD-1 in Human T Cells

Jocelynn Pearl, PhD, Fyodor D Urnov, PhD, John A Stamatoyannopoulos, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3493.
https://doi.org/10.1182/blood-2018-99-119011
Published: 2018
Journal Articles

Dysregulation of RUNX3 in Aged Human HSPCs May Contribute to Perturbations in Erythropoiesis and Balanced Lineage Output

Peter Balogh, Brian Capaldo, PhD, Sandeep Singh, PhD, Kamaleldin Elagib, MBBS, PhD, Hui Li, PhD, Eli Zunder, PhD, Maria E. Figueroa, MD, Wendy Pang, MD, Adam Goldfarb, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2553.
https://doi.org/10.1182/blood-2018-99-115245
Published: 2018
Journal Articles

DNA Methylation Identifies Genetically and Prognostically Distinct Subtypes of MDS

Brian M Reilly, BS, Tiffany N Tanaka, MD, Dinh Diep, PhD, Huwate Yeerna, BS, Pablo Tamayo, PhD, Kun Zhang, PhD, Rafael Bejar, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 106.
https://doi.org/10.1182/blood-2018-99-111535
Published: 2018
Journal Articles

Mll -Partial Tandem Duplication ( Mll -PTD) Causes Pseudohypoxia and Hypermethylation of the Epigenome through Suppression of Mitochondrial Complex II

Asumi Yokota, PhD, Lulu Zhang, PhD, Xiaomei Yan, MD PhD, Xiaomin Feng, MD PhD, Lijun Wen, MS, George Freudiger, Maria Rife, Ally Woeste, Yoshihiro Hayashi, MD PhD, Gang Huang, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1311.
https://doi.org/10.1182/blood-2018-99-112529
Published: 2018
Journal Articles

Disruption of TET2 Dioxygenase Enhances Antitumor Efficiency in CD8+ Tumor Infiltrating Lymphocytes

Minjung Lee, MS, Hongxiang Zeng, PhD, Jia Li, PhD, Wei Han, MS, Deqiang Sun, PhD, Yun Huang, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 860.
https://doi.org/10.1182/blood-2018-99-115405
Published: 2018
Journal Articles

CRISPR Activation Screen for Drivers of MM Cell Proliferation

Huihui Tang, PhD, Ricardo De Matos Simoes, PhD, Ryosuke Shirasaki, MD PhD, Olga Dashevsky, PhD, Brian Glassner, PhD, Sondra L. Downey-Kopyscinski, PhD, Sara Gandolfi, MD, Michal Sheffer, PhD, Megan Bariteau, BSc, John G Doench, PhD, Constantine S. Mitsiades, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3197.
https://doi.org/10.1182/blood-2018-99-118712
Published: 2018
Journal Articles

Integrative Oncogenomic Analysis Combining Whole Genome, Transcriptome and Epigenome Identifies Altered Chromatin Accessibility Landscape in Multiple Myeloma

Raphael Szalat, MD, Mehmet Kemal Samur, PhD, Christopher J. Ott, PhD, Matthew Lawlor, Charles Epstein, Brian J Abraham, PhD, Charles Y Lin, PhD, Linying Zhang, Rao Prabhala, PhD, Nina Farrell, Kenneth Wes, Yu-Tzu Tai, PhD, Mariateresa Fulciniti, PhD, Giovanni Parmigiani, Richard A. Young, PhD, Kenneth C Anderson, MD, Nikhil Munshi, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 328.
https://doi.org/10.1182/blood.V130.Suppl_1.328.328
Published: 2017
Journal Articles

Integration of Functional Dependencies and Molecular Alterations of Myeloma Cells

Ricardo De Matos Simoes, PhD, Geoffrey Matthews, PhD, Ryosuke Shirasaki, MD PhD, Hu Yiguo, PhD, Michal Sheffer, PhD, Olga Dashevsky, PhD, Sara Gandolfi, MD, Paul Hengeveld, Johanna Bruggenthies, Eugen Dhimolea, PhD, Huihui Tang, PhD, Megan Bariteau, Andrew Aguirre, MD PhD, Quinlan Sievers, BA, Benjamin L. Ebert, MD PhD, Brian Glassner, PhD, Christopher J. Ott, PhD, Dennis Buckley, Nicholas P Kwiatkowski, PhD, Jonathan D. Licht, MD, Nathanael Gray, PhD, Joshua Dempster, PhD, Richard WJ Groen, PhD, Francisca Vazquez, PhD, Aviad Tsherniak, PhD, William C. Hahn, MD PhD, Aedin Culhane, PhD, Constantine S. Mitsiades, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1212.
https://doi.org/10.1182/blood.V130.Suppl_1.1212.1212
Published: 2017