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Journal Articles

Red blood cell microvesicles activate the contact system, leading to factor IX activation via 2 independent pathways

Denis F. Noubouossie, Michael W. Henderson, Micah Mooberry, Anton Ilich, Patrick Ellsworth, Mark Piegore, Sarah C. Skinner, Rafal Pawlinski, Ian Welsby, Thomas Renné, Maureane Hoffman, Dougald M. Monroe, Nigel S. Key
Journal: Blood
Blood (2020) 135 (10): 755–765.
https://doi.org/10.1182/blood.2019001643
Published: 2020
Includes: Supplemental data
Journal Articles

Protease activity in single-chain prekallikrein

Ivan Ivanov, Ingrid M. Verhamme, Mao-fu Sun, Bassem Mohammed, Qiufang Cheng, Anton Matafonov, S. Kent Dickeson, Kusumam Joseph, Allen P. Kaplan, David Gailani
Journal: Blood
Blood (2020) 135 (8): 558–567.
https://doi.org/10.1182/blood.2019002224
Published: 2020
Includes: Supplemental data
Journal Articles

The Safety of Novel Drugs Targeting Factor XI and XII in Human Clinical Trials:a Systematic Review

Gillian E Mair, Sven Reid Olson, MD, Joseph J Shatzel, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4966.
https://doi.org/10.1182/blood-2019-130823
Published: 2019
Journal Articles

Antithrombin- and Heparin-Binding Exosites Regulate Extravascular Binding and Clearance of Factor IXa

Pamela Westmark, PhD, John P. Sheehan, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2392.
https://doi.org/10.1182/blood-2019-131580
Published: 2019
Journal Articles

Aberrant Cathepsin S Induces a Supportive Immune Microenvironment in Follicular Lymphoma

Johannes Adrian Hildebrand, MSc, BSc, Deepak Bararia, Sebastian Stolz, Sarah Haebe, MD, Stefan Alig, Michael Bartoschek, Michael Boesl, Alessandro Pastore, Erik Gaitzsch, Michael Heide, Vindi Jurinovic, MSc, Monika Szczepanowski, Wolfram Klapper, Abner Louissaint, Jr., MD PhD, Christina Ludwig, Sebastian Bultmann, Heinrich Leonhardt, Sebastian Eustermann, Karl-Peter Hopfner, Wolfgang Hiddemann, MD PhD, Michael von Bergwelt, Christian Steidl, MD, Robert Kridel, MDMPH,PhD, David M Weinstock, Marc Schmidt-Supprian, Menyhárt B Sárosi, Verena Passerini, Josef Mautner, Oliver Weigert
Journal: Blood
Blood (2019) 134 (Supplement_1): 657.
https://doi.org/10.1182/blood-2019-122663
Published: 2019
Journal Articles

NMR structure determination of Ixolaris and factor X(a) interaction reveals a noncanonical mechanism of Kunitz inhibition

Viviane S. De Paula, Nikolaos G. Sgourakis, Ivo M. B. Francischetti, Fabio C. L. Almeida, Robson Q. Monteiro, Ana Paula Valente
Journal: Blood
Blood (2019) 134 (8): 699–708.
https://doi.org/10.1182/blood.2018889493
Published: 2019
Includes: Supplemental data
Journal Articles

MAA868 locks factor XIa in a zymogen-like state

Jeffrey I. Weitz, Noel C. Chan
Journal: Blood
Blood (2019) 133 (13): 1393–1394.
https://doi.org/10.1182/blood-2019-02-900480
Published: 2019
Journal Articles

MAA868, a novel FXI antibody with a unique binding mode, shows durable effects on markers of anticoagulation in humans

Alexander W. Koch, Nikolaus Schiering, Samu Melkko, Stefan Ewert, Janeen Salter, Yiming Zhang, Peter McCormack, Jianying Yu, Xueming Huang, Yu-Hsin Chiu, Zhiping Chen, Simone Schleeger, Geraldine Horny, Keith DiPetrillo, Lionel Muller, Andreas Hein, Frederic Villard, Meike Scharenberg, Paul Ramage, Ulrich Hassiepen, Serge Côté, Julie DeGagne, Carsten Krantz, Jörg Eder, Brian Stoll, Kenneth Kulmatycki, David L. Feldman, Peter Hoffmann, Craig T. Basson, Robert J. A. Frost, Yasser Khder
Journal: Blood
Blood (2019) 133 (13): 1507–1516.
https://doi.org/10.1182/blood-2018-10-880849
Published: 2019
Includes: Supplemental data
Journal Articles

Heavy chain of FXII: not an innocent bystander!

Helen Philippou
Journal: Blood
Blood (2019) 133 (10): 1008–1009.
https://doi.org/10.1182/blood-2019-01-895110
Published: 2019
Journal Articles

Activated Protein C Induces Stabilization of the Outer Retinal Barrier and Inhibits Laser Induced Choroidal Neovascularization in a Murine Model

Tami Livnat, PhD, Yael Nisgav, Msc, Ivan Budnik, MDPhD, Yehonatan Weinberger, MD, Rima Dardik, PhD, Gili Kenet, MD, Dov Weinberger, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 73.
https://doi.org/10.1182/blood-2018-99-111375
Published: 2018
Journal Articles

The Complete Dependence of Factor IX Padua (R338L) Hyperactivity on Factor VIIIa Cofactor Activity Supports Its Safety As a Transgene for Hemophilia B Gene Therapy

Benjamin J. Samelson-Jones, MD PhD, John D. Finn, PhD, Rodney M. Camire, PhD, Valder R Arruda, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3486.
https://doi.org/10.1182/blood-2018-99-119270
Published: 2018
Journal Articles

Efficacy of Anti-TFPI Antibody PF-06741086 Alone and in Combination with Activated Prothrombin Complex Concentrates in Mouse Hemophilia a Bleeding Model

Amey Barakat, Reema Jasuja, PhD, John E. Murphy, PhD, Debra D Pittman, MS
Journal: Blood
Blood (2018) 132 (Supplement 1): 2460.
https://doi.org/10.1182/blood-2018-99-118431
Published: 2018
Journal Articles

Oxidized Mitochondrial DNA Is a Catalyst and Biomarker of Pyroptotic Cell Death in Myelodysplastic Syndromes

Grace A Ward, BS, Kathy L McGraw, PhD, Amy F McLemore, M.S., Farnoosh Abbas-Aghababazadeh, PhD, Hsin-An Hou, MD PhD, Thu Le Trinh, PhD, Nicole D. Vincelette, PhD, Benjamin S. Meyer, Alexis H Onimus, BS, Alexandra Calescibetta, Erika A Eksioglu, PhD MS, Sheng Wei, MD, Alan F. List, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3076.
https://doi.org/10.1182/blood-2018-99-118493
Published: 2018
Journal Articles

Role of Protease Exosites for In Vivo Hemostatic Activity and Clearance of FIX

Pamela Westmark, PhD, John Sheehan, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1166.
https://doi.org/10.1182/blood-2018-99-120212
Published: 2018
Journal Articles

Activated protein C, protease activated receptor 1, and neuroprotection

John H. Griffin, Berislav V. Zlokovic, Laurent O. Mosnier
Journal: Blood
Blood (2018) 132 (2): 159–169.
https://doi.org/10.1182/blood-2018-02-769026
Published: 2018
Journal Articles

Novel therapeutics for hemophilia and other bleeding disorders

Clinical Trials & Observations
Michael U. Callaghan, Robert Sidonio, Steven W. Pipe
Journal: Blood
Blood (2018) 132 (1): 23–30.
https://doi.org/10.1182/blood-2017-09-743385
Published: 2018
Journal Articles

Graft-Vs-Leukemia Effect in Acute Lymphoblastic Leukemia: Mild Acute Graft-Vs-Host Disease Protects Against Relapse and Improves Survival after Allogeneic Transplantation: A CIBMTR Analysis

Moshe Yeshurun, Daniel J. Weisdorf, MD, Mei-Jie Zhang, PhD, Hai-Lin Wang, MPH, Mary E. Flowers, MD, Marcos De Lima, MD, Jacob M. Rowe, MD, Brenda M. Sandmaier, MD, Martin S. Tallman, MD, Michael R Verneris, MD, Veronika Bachanova, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 518.
https://doi.org/10.1182/blood.V130.Suppl_1.518.518
Published: 2017
Journal Articles

Enhanced In Vivo Persistence and Proliferation of NK Cells Expanded in Culture with the Small Molecule Nicotinamide: Development of a Clinical-Applicable Method for NK Expansion

Tony Peled, Guy Brachya, Nurit Persi, Chana Lador, Esti Olesinski, Efrat Landau, Einat Galamidi, Amnon Peled, Jeffrey S. Miller, MD, Veronika Bachanova, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 657.
https://doi.org/10.1182/blood.V130.Suppl_1.657.657
Published: 2017
Journal Articles

Patient-Reported Quality of Life (QoL) Following CTL019 Infusion in Adult Patients (pts) with Relapsed/Refractory (r/r) Diffuse Large B-Cell Lymphoma (DLBCL)

Richard Thomas Maziarz, MD, Michael R. Bishop, MD, Constantine S. Tam, MBBS, MD FRACP, FRCPA, Peter Borchmann, MD, Ulrich Jaeger, MD, Joseph P. McGuirk, DO, Edmund K. Waller, MD, Samantha Jaglowski, MD, Charalambos Andreadis, MD MSCE, Stephen Ronan Foley, MD FRCPC, Isabelle Fleury, MD MSc, FRCP, Stephan Mielke, MD, Jason R. Westin, MD, Phoebe Joy Ho, Veronika Bachanova, MD PhD, Harald Holte, John M. Magenau, MD, Oezlem Anak, MD, Lida Bubuteishvili Pacaud, MD, Siegbert Guenther, Jie Zhang, PhD, Lawrence Rasouliyan, MPH, Feng Tai, PhD, Gilles Salles, MD PhD, Stephen J. Schuster, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 5215.
https://doi.org/10.1182/blood.V130.Suppl_1.5215.5215
Published: 2017
Journal Articles

Pre-Transplant Exhausted Marrow Infiltrating T Lymphocytes in MRD Negative Patients with Acute Leukemia Predict Early Relapse Following Allogeneic Hematopoietic Stem Cell Transplantation

Robin Williams, MDMS, Sarah Cooley, MD, Peter M. Gordon, MDPhD, Veronika Bachanova, MD PhD, Daniel J. Weisdorf, MD, Bruce Blazar, MD, John E. Wagner, MD, Jeffrey S. Miller, MD, Michael R Verneris, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1997.
https://doi.org/10.1182/blood.V130.Suppl_1.1997.1997
Published: 2017