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Journal Articles

TGF-β Signaling Contributes to Myelofibrosis and Clonal Dominance of Myeloproliferative Neoplasms

Juo-Chin Yao, Grazia Abou Ezzi, PhD, Joseph R. Krambs, BS, Salil Uttarwar, Eric J. Duncavage, MD, Daniel C. Link, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 470.
https://doi.org/10.1182/blood-2019-128943
Published: 2019
Journal Articles

Inducible Expression of Mutant ELANE Correlates with Disruption of Differentiation Program, but Not the Unfolded Protein Response

Bhavuk Garg, PhD, Hrishikesh M Mehta, PhD, Ralph Kamel, Marshall S. Horwitz, MD PhD, Seth J. Corey, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 103.
https://doi.org/10.1182/blood-2019-127409
Published: 2019
Journal Articles

P53 Pathway Activation Mediated High c-MAF Expression Is Associated with Overall and Post-Progression Survival in Multiple Myeloma

Eiko Yamane, Master, Graduate Student, Tsukasa Oda, PhD, Masanobu Sunaga, Master, Graduate Student, Yuki Murakami, Master, Graduate Student, Rei Ishihara, Master, Graduate Student, Yuta Asao, Graduate Student, Yuta Masuda, Master, Saki Watanabe, Master, Nobuhiko Kobayashi, MD PhD, Hisashi Takei, MD, Yohei Osaki, MD PhD, Gotoh Nanami, Tetsuhiro Kasamatsu, PhD, Hiroaki Shimizu, MD PhD, Takuma Ishizaki, MD PhD, Hiromi Koiso, MD PhD, Makiko Takizawa, MD PhD, Yoshiyuki Ogawa, MD PhD, Akihiko Yokohama, MD PhD, Norifumi Tsukamoto, MD PhD, Takayuki Saitoh, MD PhD, Hirokazu Murakami, MD PhD, Hiroshi Handa, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4330.
https://doi.org/10.1182/blood-2019-125172
Published: 2019
Journal Articles

R-2HG/KDM2B/RIPK1 Signaling Mediates Necroptosis in Myelodysplastic Syndromes

Shuanghong Zhu, Chen Mei, Hongyan Tong, Jie Jin, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5049.
https://doi.org/10.1182/blood-2019-125482
Published: 2019
Journal Articles

Leukemic Cell with a Novel Kinase Fusion Gene SPAG9-JAK2 Exhibits High Sensitivity to Ruxolitinib

Azusa Mayumi, MD, Toshihiro Tomii, MD, Toshihiko Imamura, MD PhD, Machiko Kawamura, MD, Hajime Hosoi, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5044.
https://doi.org/10.1182/blood-2019-126592
Published: 2019
Journal Articles

Ex vivo Engineering of Platelets

Koji Eto, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): SCI-6.
https://doi.org/10.1182/blood-2019-121116
Published: 2019
Journal Articles

MAPK-ERK Pathway Activation: The Achilles' Heel of IL-7R‒Induced Steroid Resistance

Jordy C.G. Van Der Zwet, MD, Jessica G.C.A.M. Buijs-Gladdines, Willem K. Smits, Zhongli Chen, MSc, Jules P.P. Meijerink, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1292.
https://doi.org/10.1182/blood-2019-124721
Published: 2019
Journal Articles

Isoform Specific Regulation of Acute Myeloid Leukemia Maintenance By Wilms Tumor 1

Sandeep Potluri, MA, MBBChir, MRCP, Salam A. Assi, PhD, Suyin Paulynn Chin, PhD, Anetta Ptasinska, PhD, Daniel Coleman, PhD, Peter Cockerill, PhD, Constanze Bonifer, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1232.
https://doi.org/10.1182/blood-2019-122533
Published: 2019
Journal Articles

Canonical Signaling By TGF Family Members in Mesenchymal Stromal Cells Is Dispensable for Hematopoietic Niche Maintenance Under Basal and Stress Conditions

Joseph R. Krambs, BS, Grazia Abou Ezzi, PhD, Juo-Chin Yao, Justin T. Li, Daniel C. Link, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1209.
https://doi.org/10.1182/blood-2019-128693
Published: 2019
Journal Articles

DNA Polymerases Pol θ/Pol η Involved in Error-Prone DNA Repair Are Highly Expressed in Multiple Myeloma and Upregulated By DNA Damage

Masanobu Sunaga, Master, Graduate Student, Tsukasa Oda, PhD, Eiko Yamane, Master, Graduate Student, Rei Ishihara, Master, Graduate Student, Yuki Murakami, Master, Graduate Student, Saki Watanabe, Master, Yuta Asao, Graduate Student, Yuta Masuda, Master, Hisashi Takei, MD, Nobuhiko Kobayashi, MD PhD, Yohei Osaki, MD PhD, Gotoh Nanami, Tetsuhiro Kasamatsu, PhD, Hiromi Koiso, MD PhD, Makiko Takizawa, MD PhD, Hiroaki Shimizu, MD PhD, Takuma Ishizaki, MD PhD, Yoshiyuki Ogawa, MD PhD, Akihiko Yokohama, MD PhD, Norifumi Tsukamoto, MD PhD, Takayuki Saitoh, MD PhD, Hirokazu Murakami, MD PhD, Hiroshi Handa, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4364.
https://doi.org/10.1182/blood-2019-125163
Published: 2019
Journal Articles

Multiple Myeloma Pathogenesis: The Role of Junb in Bone Marrow Angiogenesis

Fengjuan Fan, PhD, Stefano Malvestiti, MD, Yujia Shen, PhD, Eugenio Morelli, MD, Yuji Mishima, MD, Anja Seckinger, Dirk Hose, MD, Latifa Bakiri, PhD, Sonia Vallet, MD, Martin Sattler, PhD, Aldo M. Roccaro, MD PhD, Hartmut Goldschmidt, MD, Martin Percherstorfer, MD, Chunyan Sun, MD PhD, Yu Hu, MD PhD, Erwin F Wagner, PhD, Piefrancesco Tassone, MD, Irene M. Ghobrial, MD, Dirk Jaeger, MD, Klaus Podar, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4341.
https://doi.org/10.1182/blood-2019-128854
Published: 2019
Journal Articles

NF-κB-Dependent Activation of the Proteasome Components, PSMD1 and PSMD3, As a Mechanism of Resistance to Imatinib

Idaly Maria Olivas, BS, Joshua Lara, BS, Rebecca Ellwood, MS, Carme Ripoll Fiol, MS, Andres J Rubio, MS, Alfonso Enrique Bencomo, PhD, Mayra Alejandra Gonzalez, BS, Georgios Nteliopoulos, PhD, Alistair Reid, BSc, PhD, Dragana Milojkovic, MBBS, MD, Jane Apperley, MB, ChB, MD, Jamshid Sorouri Khorashad, MD PhD FRCPath, Anna M. Eiring, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2923.
https://doi.org/10.1182/blood-2019-126963
Published: 2019
Journal Articles

Gfi1 Upregulates c-Myc Expression and Promotes c-Myc-Driven Cell Proliferation

Yangyang Zhang, MD, Fan Dong, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3769.
https://doi.org/10.1182/blood-2019-124833
Published: 2019
Journal Articles

The Clinical and Functional Relevance of the Transforming AKT E17K Mutation in T-ALL

Jordy C.G. Van Der Zwet, MD, Jessica G.C.A.M. Buijs-Gladdines, Izabela Mollova, BSc, Laura Graus, BSc, Frank L. Bos, PhD, Anne C. Rios, PhD, Jules P.P. Meijerink, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3804.
https://doi.org/10.1182/blood-2019-124669
Published: 2019
Journal Articles

Adult Hematopoietic Stem and Progenitor Cell Maintenance Requires Histone Variant H3.3 Regulation By Hira

Rebecca Murdaugh, BS, Kevin Hoegenauer, Xiangguo Shi, PhD, Ayumi Kitano, Richard Chapple, PhD, Tianyuan Hu, PhD, Jonathan Tiessen, BS, Daisuke Nakada, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2473.
https://doi.org/10.1182/blood-2019-131358
Published: 2019
Journal Articles

Marcks Is a Critical Downstream Mediator of IL-1-Driven AML Progression

Mona M.Hosseini, BS, Hsin-Yun Lin, MS, Gabby Dewson, BA, Ruthey Vivier, Anupriya Agarwal, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2679.
https://doi.org/10.1182/blood-2019-129427
Published: 2019
Journal Articles

Doxycycline Combined with Bortezomib-Cyclophosphamide-Dexamethasone Chemotherapy for Newly Diagnosed Patients with Mayo 2004 Stage II-III Light-Chain Amyloidosis: A Randomized Controlled Multicenter Study

Kaini Shen, MD, Yujun Dong, MD, Weijun Fu, Sr., MD PhD, Yu Wu, MD, Zhongxia Huang, Yongqiang Wei, PhD, Chunrui Li, MD PhD, Chunyan Sun, MD PhD, Wenrong Huang, Huihan Wang, MD PhD, Congli Zhang, Huilei Miao, Lu Zhang, MD, Xinxin Cao, MD, Daobin Zhou, MD, Jian Li, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1870.
https://doi.org/10.1182/blood-2019-122087
Published: 2019
Journal Articles

Gck Kinase Activity Is Critical for RAS Mutated Myeloma - a Potential Treatment Approach for Targeting Specific Mutations

Shirong Li, PhD, Jing Fu, PhD, Xiaoming Xu, PhD, Shixian Deng, PhD, Markus Y Mapara, MD PhD, Christophe Marcireau, Suzanne Lentzsch, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1813.
https://doi.org/10.1182/blood-2019-129531
Published: 2019
Journal Articles

TET Dioxygenase Inhibition As a Therapeutic Strategy in TET2 Mutant Myeloid Neoplasia

Yihong Guan, PhD, Anand D. Tiwari, PhD, James G Phillips, PhD, Metis Hasipek, PhD, Dale Grabowski, BS, Cassandra M Kerr, MS, Vera Adema, PhD, Yasunobu Nagata, MD PhD, Valeria Visconte, PhD, Tomas Radivoyevitch, PhD, Daniel Lindner, MD PhD, Manja Meggendorfer, PhD, Mohamed Abazeed, Mikkael A. Sekeres, MD MS, Torsten Haferlach, MD, Jaroslaw P. Maciejewski, MD PhD, Babal K. Jha, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 880.
https://doi.org/10.1182/blood-2019-131920
Published: 2019
Journal Articles

Characterization of a Genetically Engineered HUDEP2 Cell Line Harboring a Sickle Cell Disease Mutation As a Potential Research Tool for Preclinical Sickle Cell Disease Drug Discovery

Dipti Gupta, Sarah Sturtevant, BSc, Benjamin Vieira, BS, Yukio Nakamura, MD PhD, Sriram Krishnamoorthy, PhD, Melanie Demers, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3559.
https://doi.org/10.1182/blood-2019-127330
Published: 2019