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Journal Articles

In Vitro Functionality of hiPSC Derived PLT+: The Utility of Microfluidic Assays in Determining Potency

Marcus Lehmann, PhD, Annie K Burton, Savannah G Szemethy, Jorge Valdez, PhD, Jonathan N. Thon, PhD

Blood (2019) 134 (Supplement_1): 1168.

https://doi.org/10.1182/blood-2019-131896

Published: 2019

Journal Articles

Environmental Cell-Matrix Adhesion Modulates Pluripotent Stem Cell Fate Toward Definitive Hemogenic Endothelium and Hematopoietic Progenitor Cells

Akinori Yuzuriha, Sou Nakamura, PhD, Toshie Kusunoki, Takuya Matsumoto, PhD, Naoshi Sugimoto, MD PhD, Kiyotoshi Sekiguchi, PhD, Koji Eto, MD PhD

Blood (2018) 132 (Supplement 1): 3845.

https://doi.org/10.1182/blood-2018-99-114505

Published: 2018

Journal Articles

Human Pluripotent Stem Cell-Derived Blood Cells for Therapies

Dan S Kaufman, MD PhD

Blood (2018) 132 (Supplement 1): SCI-14.

https://doi.org/10.1182/blood-2018-99-109424

Published: 2018

Journal Articles

Soluble Guanylate Cyclase Modulators Effect Fetal Hemoglobin Levels through a Non-cGMP-Protein Kinase G Signaling Pathway

Bin Sun, PhD, Valerie Miller, MS, Karin P Potoka, MD, Yukio Nakamura, MD PhD, Mark T Gladwin, MD, Grant C. Bullock, MD PhD

Blood (2018) 132 (Supplement 1): 1060.

https://doi.org/10.1182/blood-2018-99-120306

Published: 2018

Journal Articles

Oxidized LDL activates blood platelets through CD36/NOX2–mediated inhibition of the cGMP/protein kinase G signaling cascade

Simbarashe Magwenzi, Casey Woodward, Katie S. Wraith, Ahmed Aburima, Zaher Raslan, Huw Jones, Catriona McNeil, Stephen Wheatcroft, Nadira Yuldasheva, Maria Febbriao, Mark Kearney, Khalid M. Naseem

Blood (2015) 125 (17): 2693–2703.

https://doi.org/10.1182/blood-2014-05-574491

Published: 2015

Includes: Multimedia, Supplemental data

Journal Articles

Autologous Hematopoietic Stem/Progenitor Cell (HSPC) Therapy For Monogenic Blood Disorders: Scalable, cGMP-Compliant Process For Generating Highly Efficient Genome Edited HSPC

Gary K Lee, PhD, Lynn Truong, Travis Wood, Jill Henley, Lee Ya-Li, Ken Kim, Yuanyue Zhou, Jianbin Wang, Ph.D., Andreas Reik, PhD, Fyodor D Urnov, PhD, Paula Cannon, Ph.D., Michael C. Holmes, PhD, Dale Ando, M.D., Martin A Giedlin, Ph.D.

Blood (2013) 122 (21): 4213.

https://doi.org/10.1182/blood.V122.21.4213.4213

Published: 2013

Journal Articles

Induced Pluripotent Stem Cells and Erythrocyte Production

Igor Slukvin, MD, PhD

Blood (2012) 120 (21): SCI-38.

https://doi.org/10.1182/blood.V120.21.SCI-38.SCI-38

Published: 2012

Journal Articles

HU for acute treatment of sickle VOC?

Wassim El Nemer

Blood (2012) 120 (14): 2777–2778.

https://doi.org/10.1182/blood-2012-08-447102

Published: 2012

Journal Articles

Response: inhibition of platelet activation by NO involves both cGMP-dependent and -independent mechanisms

Zhenyu Li

Blood (2012) 119 (22): 5339.

https://doi.org/10.1182/blood-2012-04-419481

Published: 2012

Journal Articles

Extra-platelet NO and NO + -containing drugs are potent inhibitors of platelet aggregation in humans by cGMP-dependent and cGMP-independent mechanisms

Dimitrios Tsikas, Markus Flentje, Jonas Niemann, Anke Böhmer, Dirk O. Stichtenoth

Blood (2012) 119 (22): 5337–5339.

https://doi.org/10.1182/blood-2012-03-414862

Published: 2012

Journal Articles

Hydroxyurea Induces Fetal Hemoglobin Expression by Activating cAMP Signaling Pathways In a cAMP- and cGMP-Dependent Manner; New Hypothesis to Account for a Role of Non-Erythroid Cells In Fetal Hemoglobin Induction

Tohru Ikuta, MD, PhD, Diana Gutsaeva, James Parkerson, Shobha Yerigenahally, C. Alvin Head

Blood (2010) 116 (21): 1622.

https://doi.org/10.1182/blood.V116.21.1622.1622

Published: 2010

Journal Articles

Adoptive Transfer of CMV-Specific Donor T Cells Following Allogeneic Transplantation Leads to Rapid and Safe Systemic Reconstitution.

Karl S Peggs, MD, Kirsty Thomson, MD, Edward Samuel, BSc, MSc, Gemma Dyer, Julie Armoogum, Kwok Pang, BSc, MSc, Ronjon Chakraverty, MD, PhD, Stephen Mackinnon, MD, Mark W Lowdell, PhD, FRCPath

Blood (2009) 114 (22): 44.

https://doi.org/10.1182/blood.V114.22.44.44

Published: 2009

Journal Articles

Purity, Potency and Safety: Quality Management Reports (QMR) as the Basis for An Effective Continuous Process Improvement System in An Academic Gene Therapy Program.

Joseph Alvarnas, MD, Amira Ahmed, MS, Nancy Gonzalez, MS, Eileen Smith, MD, Diana Russom, Larry Couture, PhD, Stephen J Forman, MD, David DiGiusto

Blood (2009) 114 (22): 1417.

https://doi.org/10.1182/blood.V114.22.1417.1417

Published: 2009

Journal Articles

Src family tyrosine kinase Lyn mediates VWF/GPIb-IX–induced platelet activation via the cGMP signaling pathway

Hong Yin, Junling Liu, Zhenyu Li, Michael C. Berndt, Clifford A. Lowell, Xiaoping Du

Blood (2008) 112 (4): 1139–1146.

https://doi.org/10.1182/blood-2008-02-140970

Published: 2008

Journal Articles

A clinical-scale selective allodepletion approach for the treatment of HLA-mismatched and matched donor-recipient pairs using expanded T lymphocytes as antigen-presenting cells and a TH9402-based photodepletion technique

Stephan Mielke, Raquel Nunes, Katayoun Rezvani, Vicki S. Fellowes, Annie Venne, Scott R. Solomon, Yong Fan, Emma Gostick, David A. Price, Christian Scotto, Elizabeth J. Read, A. John Barrett

Blood (2008) 111 (8): 4392–4402.

https://doi.org/10.1182/blood-2007-08-104471

Published: 2008

Includes: Supplemental data

Journal Articles

Thrombospondin-1 stimulates platelet aggregation by blocking the antithrombotic activity of nitric oxide/cGMP signaling

Jeff S. Isenberg, Martin J. Romeo, Christine Yu, Christine K. Yu, Khauh Nghiem, Jude Monsale, Margaret E. Rick, David A. Wink, William A. Frazier, David D. Roberts

Blood (2008) 111 (2): 613–623.

https://doi.org/10.1182/blood-2007-06-098392

Published: 2008

Journal Articles

The role of Akt in the signaling pathway of the glycoprotein Ib-IX–induced platelet activation

Hong Yin, Aleksandra Stojanovic, Nissim Hay, Xiaoping Du

Blood (2008) 111 (2): 658–665.

https://doi.org/10.1182/blood-2007-04-085514

Published: 2008

Includes: Supplemental data

Journal Articles

The Biologic Meaning of the Structural Components of Defibrotide (DF) in the Setting of HIV Disease with Refractory Herpes, Candida, Cryptosporidium Diarrhea and Multi-Organ Failure Against the Background of Down-Regulation of Cellular Immunity, Autocrine Upregulation of Inflammatory Cytokines of TNF-Alpha, IL2, IL1, IL6 and Dysregulation of cAMP/cGMP Protein Kinase A/C Signalling.

Arsinur D. Burcoglu-Oral, MD

Blood (2007) 110 (11): 3865.

https://doi.org/10.1182/blood.V110.11.3865.3865

Published: 2007

Journal Articles

LPS Stimulates Platelet Secretion and Promotes Platelet Aggregation Via TLR4/MyD88 and the cGMP-Dependent Protein Kinase Pathway.

Guoying Zhang, MD, Emily Welch, BS, Asrar B. Malik, PhD, Xiaoping Du, MD, PhD, Zhenyu Li, MD, PhD

Blood (2007) 110 (11): 3658.

https://doi.org/10.1182/blood.V110.11.3658.3658

Published: 2007

Journal Articles

The Roles of Akt1 and Akt2 in GPIb-IX-Mediated Platelet Activation Signaling.

Hong Yin, MD, Aleksandra Stojanovic, BS, Nissim Hay, PhD, Xiaoping Du, MD, PhD

Blood (2007) 110 (11): 3635.

https://doi.org/10.1182/blood.V110.11.3635.3635

Published: 2007

NARROW

In Vitro Functionality of hiPSC Derived PLT+: The Utility of Microfluidic Assays in Determining Potency

Environmental Cell-Matrix Adhesion Modulates Pluripotent Stem Cell Fate Toward Definitive Hemogenic Endothelium and Hematopoietic Progenitor Cells

Human Pluripotent Stem Cell-Derived Blood Cells for Therapies

Soluble Guanylate Cyclase Modulators Effect Fetal Hemoglobin Levels through a Non-cGMP-Protein Kinase G Signaling Pathway

Oxidized LDL activates blood platelets through CD36/NOX2–mediated inhibition of the cGMP/protein kinase G signaling cascade

Autologous Hematopoietic Stem/Progenitor Cell (HSPC) Therapy For Monogenic Blood Disorders: Scalable, cGMP-Compliant Process For Generating Highly Efficient Genome Edited HSPC

Induced Pluripotent Stem Cells and Erythrocyte Production

HU for acute treatment of sickle VOC?

Response: inhibition of platelet activation by NO involves both cGMP-dependent and -independent mechanisms

Extra-platelet NO and NO + -containing drugs are potent inhibitors of platelet aggregation in humans by cGMP-dependent and cGMP-independent mechanisms

Hydroxyurea Induces Fetal Hemoglobin Expression by Activating cAMP Signaling Pathways In a cAMP- and cGMP-Dependent Manner; New Hypothesis to Account for a Role of Non-Erythroid Cells In Fetal Hemoglobin Induction

Adoptive Transfer of CMV-Specific Donor T Cells Following Allogeneic Transplantation Leads to Rapid and Safe Systemic Reconstitution.

Purity, Potency and Safety: Quality Management Reports (QMR) as the Basis for An Effective Continuous Process Improvement System in An Academic Gene Therapy Program.

Src family tyrosine kinase Lyn mediates VWF/GPIb-IX–induced platelet activation via the cGMP signaling pathway

A clinical-scale selective allodepletion approach for the treatment of HLA-mismatched and matched donor-recipient pairs using expanded T lymphocytes as antigen-presenting cells and a TH9402-based photodepletion technique

Thrombospondin-1 stimulates platelet aggregation by blocking the antithrombotic activity of nitric oxide/cGMP signaling

The role of Akt in the signaling pathway of the glycoprotein Ib-IX–induced platelet activation

LPS Stimulates Platelet Secretion and Promotes Platelet Aggregation Via TLR4/MyD88 and the cGMP-Dependent Protein Kinase Pathway.

The Roles of Akt1 and Akt2 in GPIb-IX-Mediated Platelet Activation Signaling.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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