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Journal Articles

CRISPR screen identifies genes that sensitize AML cells to double-negative T-cell therapy

Fraser Soares, Branson Chen, Jong Bok Lee, Musaddeque Ahmed, Dalam Ly, Enoch Tin, Hyeonjeong Kang, Yong Zeng, Nayeema Akhtar, Mark D. Minden, Housheng Hansen He, Li Zhang

Blood (2021) 137 (16): 2171–2181.

https://doi.org/10.1182/blood.2019004108

Published: 2021

Includes: Supplemental data

Journal Articles

A Functional Analysis of SNP on Anthracycline-Induced Cardiotoxicity in a Uniform Genetic Background Using CRISPR/Cas9 Mediated Single-Base-Edited iPSCs

Takayuki Nakamura, MD, Shinichi Mizuno, MD PhD, Hidetoshi Ozawa, Yoshitaka Yamasaki, MD, Shuki Oya, MD, Satoshi Morishige, MD, Kazutoshi Aoyama, MD PhD, Maki Ymaguchi, MD PhD, Ritsuko Seki, PhD, Fumihiko Mouri, MD PhD, Koichi Osaki, MD, Koji Nagafuji, MD PhD

Blood (2019) 134 (Supplement_1): 5748.

https://doi.org/10.1182/blood-2019-123932

Published: 2019

Journal Articles

Invariant NKT Cells Recognize Leukemia Cells with T-Cell and NK Receptors in a CD1d-Independent Manner

Takahiro Aoki, MD, Mariko Takami, Tomozumi Takatani, Kiwamu Motoyoshi, Ayana Ishii, Ayaka Hara, Takahide Toyoda, Reona Okada, Moeko Hino, MD, Ryo Koyama-Nasu, Masahiro Kiuchi, Kiyoshi Hirahara, Toshinori Nakayama, Naoki Shimojo, Shinichiro Motohashi

Blood (2019) 134 (Supplement_1): 3225.

https://doi.org/10.1182/blood-2019-121817

Published: 2019

Journal Articles

Enumerating Functional HSC Clones in the Zebrafish Using Gestalt

Emily M Teets, B.S., Charles Thomas Gregory, BS, Jami L Shaffer, B.S., James S. Blachly, MD, Bradley W Blaser, MD PhD

Blood (2019) 134 (Supplement_1): 3724.

https://doi.org/10.1182/blood-2019-131503

Published: 2019

Journal Articles

Mice Deficient in ß2-Glycoprotein I Have a Delayed Time to Thrombosis

Ravi Kumar Alluri, PhD, Gabriel L Forbes, Suman Kundu, MBA, Alvin H. Schmaier, MD, Keith R McCrae, MD

Blood (2019) 134 (Supplement_1): 2423.

https://doi.org/10.1182/blood-2019-130521

Published: 2019

Journal Articles

First-in-Human Assessment of Feasibility and Safety of Multiplexed Genetic Engineering of Autologous T Cells Expressing NY-ESO -1 TCR and CRISPR/Cas9 Gene Edited to Eliminate Endogenous TCR and PD-1 (NYCE T cells) in Advanced Multiple Myeloma (MM) and Sarcoma

Blood (2019) 134 (Supplement_1): 49.

https://doi.org/10.1182/blood-2019-122374

Published: 2019

Journal Articles

Next Generation CRISPR Gene-Edited and Off-the-Shelf Virus-Specific T-Cells for the Immunocompromised Patient

Blood (2019) 134 (Supplement_1): 1944.

https://doi.org/10.1182/blood-2019-125276

Published: 2019

Journal Articles

Modeling the Initiation and Evolution of Down Syndrome Associated Leukemia Using CRISPR/Cas9

Elvin Wagenblast, PhD, Gabriela Krivdova, BSc, MSc, Lorien Shakib, Maria Azkanaz, Olga I. Gan, Eric R. Lechman,, PhD MSC, John E. Dick

Blood (2018) 132 (Supplement 1): 3891.

https://doi.org/10.1182/blood-2018-99-110363

Published: 2018

Journal Articles

Comprehensive Integrated Genomic Perturbations Reveal Molecular Mechanisms of Red Blood Cell Trait Associations

Yuxuan Wu, PhD, Mitchel A. Cole, BS, Abdou Mousas, Jing Zeng, MD, Qiuming Yao, PhD, Divya Vinjamur, PhD, Ryo Kurita, PhD, Yukio Nakamura, MD PhD, Luca Pinello, PhD, Guillame Lettre, PhD, Daniel E. Bauer, MD PhD

Blood (2018) 132 (Supplement 1): 532.

https://doi.org/10.1182/blood-2018-99-120229

Published: 2018

Journal Articles

Engineered Human Umbilical Cord Derived Erythroid Progenitor Cells (HUDEP2) with Sickle or β-Thalassemia Mutation: An in-Vitro System for Testing Pharmacological Induction of Fetal Hemoglobin

So Hyun Park, BS, Ciaran M Lee, PhD, Yankai Zhang, PhD, Alicia Chang, MD, Vivien A Sheehan, MD PhD, Gang Bao, PhD

Blood (2018) 132 (Supplement 1): 3478.

https://doi.org/10.1182/blood-2018-99-114241

Published: 2018

Journal Articles

Disruption of SOCS3 Promotes the Anti-Cancer Efficacy of Primary NK Cells

Meisam Naeimi Kararoudi, PhD DVM, Ezgi Elmas, MS, Margaret Lamb, MD, Nitin Chakravarti, PhD, Prashant Trikha, PhD, Dean Anthony Lee, MD PhD

Blood (2018) 132 (Supplement 1): 5687.

https://doi.org/10.1182/blood-2018-99-116621

Published: 2018

Journal Articles

A Method to Fluorescently Label the CRISPR/Cas9-gRNA RNP Complexes Enables Enrichment of Clinical-Grade Gene-Edited Primary Hematopoietic Stem Cells and iPSCs

Masoud Nasri, Perihan Mir, Benjamin Dannenmann, Diana Amend, Yun Xu, Anna Solovyeva, Sylwia Stefanczyk, Maksim Klimiankou, Cornelia Zeidler, Lothar Kanz, Karl Welte, Julia Skokowa, MDPhD

Blood (2018) 132 (Supplement 1): 1108.

https://doi.org/10.1182/blood-2018-99-114844

Published: 2018

Journal Articles

Modeling Human Paroxysmal Nocturnal Hemoglobinuria Via CRISPR/Cas9 HSPC Gene Editing in Non-Human Primate

Taehoon Shin, PhD, Eun Jung Baek, MD, Marcus A.F. Corat, PhD, Shirley Chen, BS, Robert E. Donahue, VMD, Kyung-Rok Yu, PhD, Cynthia E. Dunbar, MD

Blood (2018) 132 (Supplement 1): 1309.

https://doi.org/10.1182/blood-2018-99-111984

Published: 2018

Journal Articles

Development of a Clinically Applicable Method for High-Efficiency Gene Correction of Plerixafor-Mobilized CD34 + Cells from Patients with Sickle Cell Disease

Naoya Uchida, MD, Linhong Li, Juan J Haro-Mora, PhD, Selami Demirci, PhD, Tina Nassehi, Jackson Gamer, Claire Drysdale, Morgan Yapundich, Cornell Allen, Suk See De Ravin, MD PhD, Harry L Malech, MD, Madhusudan Peshwa, PhD, John F. Tisdale, MD

Blood (2018) 132 (Supplement 1): 2191.

https://doi.org/10.1182/blood-2018-99-111677

Published: 2018

Journal Articles

Highly Efficient Editing of the Beta-Globin Gene in Patient Derived Hematopoietic Stem and Progenitor Cells to Treat Sickle Cell Disease

So Hyun Park, BS, Ciaran M Lee, PhD, Daniel P. Dever, PhD, Timothy H Davis, BS, Joab Camarena, BS, Yankai Zhang, PhD, Matthew Porteus, MD PhD, Vivian A Sheehan, MD PhD, Gang Bao, PhD

Blood (2018) 132 (Supplement 1): 2192.

https://doi.org/10.1182/blood-2018-99-117371

Published: 2018

Journal Articles

Engineering Resistance to CD33-Targeted Immunotherapy in Normal Hematopoiesis By CRISPR/Cas9-Deletion of CD33 Exon 2

Roland B. Walter, MD PhD MS, Olivier Humbert, PhD, George S. Laszlo, PhD, Sophie R. Sichel, BS, Christina M. Ironside, BS, Kevin G. Haworth, PhD, Olivia M. Bates, BA, Mary E. Beddoe, BS, Ray R. Carillo, BS, Hans-Peter Kiem, MD PhD

Blood (2018) 132 (Supplement 1): 2200.

https://doi.org/10.1182/blood-2018-99-117856

Published: 2018

Journal Articles

Visualizing Clonal Hematopoiesis Associated with gata2 Deficiency in Zebrafish Using Color-Barcoding

Serine Avagyan, MD PhD, William Mannherz, Leonard I. Zon, MD

Blood (2017) 130 (Supplement 1): 4237.

https://doi.org/10.1182/blood.V130.Suppl_1.4237.4237

Published: 2017

Journal Articles

Chimeric Antigen Receptor (CAR) T Cell Therapy for CD7-Positive Acute Myeloid Leukemia

Diogo Gomes-Silva, Haruko Tashiro, MD PhD, Madhuwanti Srinivasan, Premal Lulla, MBBS, Malcolm K. Brenner, MD PhD, Maksim Mamonkin, PhD

Blood (2017) 130 (Supplement 1): 2642.

https://doi.org/10.1182/blood.V130.Suppl_1.2642.2642

Published: 2017

Journal Articles

Aryl hydrocarbon receptor inhibition promotes hematolymphoid development from human pluripotent stem cells

Mathew G. Angelos, Paige N. Ruh, Beau R. Webber, Robert H. Blum, Caitlin D. Ryan, Laura Bendzick, Seonhui Shim, Ashley M. Yingst, Dejene M. Tufa, Michael R. Verneris, Dan S. Kaufman

Blood (2017) 129 (26): 3428–3439.

https://doi.org/10.1182/blood-2016-07-730440

Published: 2017

Includes: Supplemental data

Journal Articles

DNA Epigenome Editing Using Crispr-Cas Suntag-Directed DNMT3A

Yung-Hsin Huang, BS, Su Jianzhong, PhD, Yong Lei, PhD, Michael C Gundry, BS, Xiaotian Zhang, BS, Mira Jeong, PhD, Wei Li, PhD, Margaret A Goodell, PhD

Blood (2016) 128 (22): 2707.

https://doi.org/10.1182/blood.V128.22.2707.2707

Published: 2016

NARROW

CRISPR screen identifies genes that sensitize AML cells to double-negative T-cell therapy

A Functional Analysis of SNP on Anthracycline-Induced Cardiotoxicity in a Uniform Genetic Background Using CRISPR/Cas9 Mediated Single-Base-Edited iPSCs

Invariant NKT Cells Recognize Leukemia Cells with T-Cell and NK Receptors in a CD1d-Independent Manner

Enumerating Functional HSC Clones in the Zebrafish Using Gestalt

Mice Deficient in ß2-Glycoprotein I Have a Delayed Time to Thrombosis

First-in-Human Assessment of Feasibility and Safety of Multiplexed Genetic Engineering of Autologous T Cells Expressing NY-ESO -1 TCR and CRISPR/Cas9 Gene Edited to Eliminate Endogenous TCR and PD-1 (NYCE T cells) in Advanced Multiple Myeloma (MM) and Sarcoma

Next Generation CRISPR Gene-Edited and Off-the-Shelf Virus-Specific T-Cells for the Immunocompromised Patient

Modeling the Initiation and Evolution of Down Syndrome Associated Leukemia Using CRISPR/Cas9

Comprehensive Integrated Genomic Perturbations Reveal Molecular Mechanisms of Red Blood Cell Trait Associations

Engineered Human Umbilical Cord Derived Erythroid Progenitor Cells (HUDEP2) with Sickle or β-Thalassemia Mutation: An in-Vitro System for Testing Pharmacological Induction of Fetal Hemoglobin

Disruption of SOCS3 Promotes the Anti-Cancer Efficacy of Primary NK Cells

A Method to Fluorescently Label the CRISPR/Cas9-gRNA RNP Complexes Enables Enrichment of Clinical-Grade Gene-Edited Primary Hematopoietic Stem Cells and iPSCs

Modeling Human Paroxysmal Nocturnal Hemoglobinuria Via CRISPR/Cas9 HSPC Gene Editing in Non-Human Primate

Development of a Clinically Applicable Method for High-Efficiency Gene Correction of Plerixafor-Mobilized CD34 + Cells from Patients with Sickle Cell Disease

Highly Efficient Editing of the Beta-Globin Gene in Patient Derived Hematopoietic Stem and Progenitor Cells to Treat Sickle Cell Disease

Engineering Resistance to CD33-Targeted Immunotherapy in Normal Hematopoiesis By CRISPR/Cas9-Deletion of CD33 Exon 2

Visualizing Clonal Hematopoiesis Associated with gata2 Deficiency in Zebrafish Using Color-Barcoding

Chimeric Antigen Receptor (CAR) T Cell Therapy for CD7-Positive Acute Myeloid Leukemia

Aryl hydrocarbon receptor inhibition promotes hematolymphoid development from human pluripotent stem cells

DNA Epigenome Editing Using Crispr-Cas Suntag-Directed DNMT3A

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American Society of Hematology

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American Society of Hematology

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