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Journal Articles

FXII inhibition: multipronged benefits

Helen Philippou

Blood (2021) 138 (2): 107–109.

https://doi.org/10.1182/blood.2021011032

Published: 2021

Journal Articles

Losing control to bad relatives

Vahid Afshar-Kharghan

Blood (2021) 137 (25): 3462–3463.

https://doi.org/10.1182/blood.2021011364

Published: 2021

Journal Articles

Molecular bases for the association of FHR-1 with atypical hemolytic uremic syndrome and other diseases

Héctor Martin Merinero, Marta Subías, Amaia Pereda, Elena Gómez-Rubio, Lucia Juana Lopez, Constantino Fernandez, Elena Goicoechea de Jorge, Sonsoles Martin-Santamaria, Francisco Javier Cañada, Santiago Rodríguez de Córdoba

Blood (2021) 137 (25): 3484–3494.

https://doi.org/10.1182/blood.2020010069

Published: 2021

Includes: Supplemental data

Journal Articles

Markers of complement activation in plasma during quiescent phases in patients with catastrophic antiphospholipid syndrome

Amelia Ruffatti, Marta Tonello, Paolo Macor, Antonia Calligaro, Teresa Del Ross, Maria Favaro, Virginia Lotti, Antonio Carletto, Ariela Hoxha, Domenico Biasi

Blood (2021) 137 (21): 2989–2992.

https://doi.org/10.1182/blood.2020010575

Published: 2021

Journal Articles

“HIT”ing back against NETs

Shadi Swaidani, Keith R. McCrae

Blood (2020) 135 (10): 706–707.

https://doi.org/10.1182/blood.2019004461

Published: 2020

Journal Articles

Complement activity and complement regulatory gene mutations are associated with thrombosis in APS and CAPS

Shruti Chaturvedi, Evan M. Braunstein, Xuan Yuan, Jia Yu, Alice Alexander, Hang Chen, Eleni Gavriilaki, Ravi Alluri, Michael B. Streiff, Michelle Petri, Mark A. Crowther, Keith R. McCrae, Robert A. Brodsky

Blood (2020) 135 (4): 239–251.

https://doi.org/10.1182/blood.2019003863

Published: 2020

Includes: Supplemental data

Journal Articles

Easix Is Strongly Associated with Complement Activation and Overall Survival in Adult Allogeneic Hematopoietic Cell Transplantation Recipients

Eleni Gavriilaki, MD, Ioanna Sakellari, Thomas Chatziconstantinou, Despina Mallouri, Ioannis Batsis, Anna Vardi, MD PhD, Zoi Bousiou, MD MSc, Evdoxia Koravou, Marianna Masmanidou, Tasoula Touloumenidou, Lila Papalexandri, MD, Anastasia Athanasiadou, MD, Evangelia Yannaki, MD, Achilles Anagnostopoulos

Blood (2019) 134 (Supplement_1): 4520.

https://doi.org/10.1182/blood-2019-125332

Published: 2019

Journal Articles

Links Between Complement Activation and Thrombosis

Wolfram Ruf, MD

Blood (2019) 134 (Supplement_1): SCI-40.

https://doi.org/10.1182/blood-2019-121113

Published: 2019

Journal Articles

Synergistic effects of ADAMTS13 deficiency and complement activation in pathogenesis of thrombotic microangiopathy

Liang Zheng, Di Zhang, Wenjing Cao, Wen-Chao Song, X. Long Zheng

Blood (2019) 134 (13): 1095–1105.

https://doi.org/10.1182/blood.2019001040

Published: 2019

Journal Articles

Natural, not immune; classical, not alternative

Theodore E. Warkentin

Blood (2018) 132 (23): 2421–2422.

https://doi.org/10.1182/blood-2018-10-880799

Published: 2018

Journal Articles

Polyreactive IgM initiates complement activation by PF4/heparin complexes through the classical pathway

Sanjay Khandelwal, Joann Ravi, Lubica Rauova, Alexandra Johnson, Grace M. Lee, Jennifer B. Gilner, Sreenivasulu Gunti, Abner L. Notkins, Maragatha Kuchibhatla, Michael Frank, Mortimer Poncz, Douglas B. Cines, Gowthami M. Arepally

Blood (2018) 132 (23): 2431–2440.

https://doi.org/10.1182/blood-2018-03-834598

Published: 2018

Includes: Supplemental data

Journal Articles

An Alternative Pathway Specific Flow Cytometric Assay to Detect Complement Activation in Atypical Hemolytic Uremic Syndrome (aHUS)

Jia Yu, Xuan Yuan, MD MSc, Kang Zhou, Daniel White, Samuel A. Merrill, MD PhD, Robert A. Brodsky, MD

Blood (2018) 132 (Supplement 1): 3748.

https://doi.org/10.1182/blood-2018-99-119445

Published: 2018

Journal Articles

Inhibition of C3 with APL-2 Results in Normalisation of Markers of Intravascular and Extravascular Hemolysis in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH)

Raymond SM Wong, MRCP, FRCP, Humphrey W.H. Pullon, FRACP, FRCPA, Pascal Deschatelets, PhD, Cedric G Francois, MD PhD, Mohamed Hamdani, MS, Surapol Issaragrisil, MD, Patrick Johnson, PhD, Pimjai Niparuck, MD, Tontanai Numbenjapon, MD, Jameela Sathar, MB, MRCP, MRCPath, Lisa Tan, Eric Tse, MBBS, PhD FRCP, FRCPath, Federico Grossi, MD

Blood (2018) 132 (Supplement 1): 2314.

https://doi.org/10.1182/blood-2018-99-110827

Published: 2018

Journal Articles

Prospective Analysis of Complement Activation in Allogeneic Transplant Recipients and Correlation with Transplant Associated Thrombotic Microangiopathy (TA-TMA) and Acute Graft Versus Host Disease (aGVHD)

Matthew Bostic, BS, MS, Qiuhong Zhao, MS, Sarah A Wall, MD, Spero R Cataland, MD, Sumithira Vasu, MD MBBS

Blood (2018) 132 (Supplement 1): 4572.

https://doi.org/10.1182/blood-2018-99-114892

Published: 2018

Journal Articles

In vivo–generated thrombin and plasmin do not activate the complement system in baboons

Ravi S. Keshari, Robert Silasi, Cristina Lupu, Fletcher B. Taylor, Jr, Florea Lupu

Blood (2017) 130 (24): 2678–2681.

https://doi.org/10.1182/blood-2017-06-788216

Published: 2017

Includes: Supplemental data

Journal Articles

Elucidation of Autoinflammatory Mechanism in Pigt-PNH

Makiko Osato, MS, Yoshiko Murakami, MD PhD, Shogo Murata, MD PhD, Jun-Ichi Nishimura, MD PhD, Yasutaka Ueda, MD PhD, Taroh Kinoshita, PhD, Yuzuru Kanakura, MD PhD

Blood (2017) 130 (Supplement 1): 2201.

https://doi.org/10.1182/blood.V130.Suppl_1.2201.2201

Published: 2017

Journal Articles

In Vitro Complement Activation By PF4/Heparin Complexes Is Mediated By Plasma IgM

Sanjay Khandelwal, PhD, Lubica Rauova, MD PhD, Mortimer Poncz, MD, Michael Frank, MD, Douglas B. Cines, MD, Gowthami Arepally, MD

Blood (2017) 130 (Supplement 1): 3617.

https://doi.org/10.1182/blood.V130.Suppl_1.3617.3617

Published: 2017

Journal Articles

Circulating dsDNA, endothelial injury, and complement activation in thrombotic microangiopathy and GVHD

Nicholas J. Gloude, Pooja Khandelwal, Nathan Luebbering, Dana T. Lounder, Sonata Jodele, Matthew N. Alder, Adam Lane, Alyss Wilkey, Kelly E. Lake, Bridget Litts, Stella M. Davies

Blood (2017) 130 (10): 1259–1266.

https://doi.org/10.1182/blood-2017-05-782870

Published: 2017

Journal Articles

Incomplete inhibition by eculizumab: mechanistic evidence for residual C5 activity during strong complement activation

Markus J. Harder, Nadine Kuhn, Hubert Schrezenmeier, Britta Höchsmann, Inge von Zabern, Christof Weinstock, Thomas Simmet, Daniel Ricklin, John D. Lambris, Arne Skerra, Markus Anliker, Christoph Q. Schmidt

Blood (2017) 129 (8): 970–980.

https://doi.org/10.1182/blood-2016-08-732800

Published: 2017

Includes: Supplemental data

Journal Articles

Bacteremia, Not Coagulation Proteases Contribute to In Vivo Complement Activation in Sepsis

Ravi Shankar Keshari, PhD, Robert Silasi-Mansat, PhD, Cristina Lupu, PhD, Fletcher B. Taylor, Jr., MD, Florea Lupu, PhD

Blood (2016) 128 (22): 275.

https://doi.org/10.1182/blood.V128.22.275.275

Published: 2016

NARROW

FXII inhibition: multipronged benefits

Losing control to bad relatives

Molecular bases for the association of FHR-1 with atypical hemolytic uremic syndrome and other diseases

Markers of complement activation in plasma during quiescent phases in patients with catastrophic antiphospholipid syndrome

“HIT”ing back against NETs

Complement activity and complement regulatory gene mutations are associated with thrombosis in APS and CAPS

Easix Is Strongly Associated with Complement Activation and Overall Survival in Adult Allogeneic Hematopoietic Cell Transplantation Recipients

Links Between Complement Activation and Thrombosis

Synergistic effects of ADAMTS13 deficiency and complement activation in pathogenesis of thrombotic microangiopathy

Natural, not immune; classical, not alternative

Polyreactive IgM initiates complement activation by PF4/heparin complexes through the classical pathway

An Alternative Pathway Specific Flow Cytometric Assay to Detect Complement Activation in Atypical Hemolytic Uremic Syndrome (aHUS)

Inhibition of C3 with APL-2 Results in Normalisation of Markers of Intravascular and Extravascular Hemolysis in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH)

Prospective Analysis of Complement Activation in Allogeneic Transplant Recipients and Correlation with Transplant Associated Thrombotic Microangiopathy (TA-TMA) and Acute Graft Versus Host Disease (aGVHD)

In vivo–generated thrombin and plasmin do not activate the complement system in baboons

Elucidation of Autoinflammatory Mechanism in Pigt-PNH

In Vitro Complement Activation By PF4/Heparin Complexes Is Mediated By Plasma IgM

Circulating dsDNA, endothelial injury, and complement activation in thrombotic microangiopathy and GVHD

Incomplete inhibition by eculizumab: mechanistic evidence for residual C5 activity during strong complement activation

Bacteremia, Not Coagulation Proteases Contribute to In Vivo Complement Activation in Sepsis

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American Society of Hematology

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American Society of Hematology

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