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Journal Articles

Genomic and transcriptomic correlates of Richter transformation in chronic lymphocytic leukemia

Jenny Klintman, Niamh Appleby, Basile Stamatopoulos, Katie Ridout, Toby A. Eyre, Pauline Robbe, Laura Lopez Pascua, Samantha J. L. Knight, Helene Dreau, Maite Cabes, Niko Popitsch, Mats Ehinger, Jose I. Martín-Subero, Elías Campo, Robert Månsson, Davide Rossi, Jenny C. Taylor, Dimitrios V. Vavoulis, Anna Schuh

Blood (2021) 137 (20): 2800–2816.

https://doi.org/10.1182/blood.2020005650

Published: 2021

Includes: Supplemental data

Journal Articles

Therapeutic Applications of a Unique Calcium Channel Blocker to Target SF3B1 MDS

Sunisa Kongkiatkamon, Anand Tiwari, Vera Adema, PhD, Cassandra M Kerr, MS, Bartlomiej Przychodzen, Hassan Awada, Jibran Durrani, Yvonne Parker, Drew Adams, Yuriy Fedorov, Hetty E. Carraway, MD MBA, Chao-Yie Yang, Mikkael A. Sekeres, MD MS, Daniel J. Lindner, James G Phillips, PhD, Jaroslaw P. Maciejewski, MD PhD, Valeria Visconte, PhD

Blood (2019) 134 (Supplement_1): 881.

https://doi.org/10.1182/blood-2019-128671

Published: 2019

Journal Articles

Lncrna Morrbid Regulates Myeloid Cell Survival of AML Driven By a Combination of FLT3ITD and Epigenetic Mutations

Zhigang Cai, PhD, Baskar Ramdas, PhD, Jonathan Kotzin, Martin P. Carroll, MD, Gerald Wertheim, MD, PhD, Adam Williams, Jorge Henao-Mejia, Reuben Kapur, PhD

Blood (2019) 134 (Supplement_1): 915.

https://doi.org/10.1182/blood-2019-130653

Published: 2019

Journal Articles

Lgr5 Functions As a Critical Negative Regulator of Wnt/β-Catenin Signaling and Is Essential for B-Lymphopoiesis and Malignant B-Cell Transformation

Kadriye Nehir Cosgun, PhD, Gauri Deb, MS, PhD, Xin Yang, MD, Gang Xiao, PhD, Teresa Sadras, PhD, Jaewoong Lee, PhD, Lai N Chan, PhD, Kohei Kume, PhD, Lu Yang, PhD, Huimin Geng, PhD, John Chan, MD, Joo Y. Song, MD, Hassan Jumaa, PhD, Andrew G. Polson, PhD, Hans Clevers, MD PhD, Markus Müschen, MD PhD

Blood (2019) 134 (Supplement_1): 748.

https://doi.org/10.1182/blood-2019-127263

Published: 2019

Journal Articles

Combined Single Cell Lineage and Transcriptome Sequencing Unveils Cell-Autonomous Regulators of Hematopoietic Stem Cell Fate

Alejo E Rodriguez-Fraticelli, PhD, Caleb S Weinreb, PhD, Allon Moshe Klein, PhD, Shou-Wen Wang, PhD, Fernando D Camargo, PhD

Blood (2019) 134 (Supplement_1): 446.

https://doi.org/10.1182/blood-2019-123447

Published: 2019

Journal Articles

Analysis of Mechanisms Underlying Clonal Evolution of AML By a New Single-Cell Sequencing Platform

Ryosaku Inagaki, MSc, Masahiro Marshall Nakagawa, MD PhD, Yasuhito Nannya, MD PhD, Qi Xingxing, PhD, Lanying Zhao, MD, PhD, June Takeda, MD, Akinori Yoda, PhD, Ayana Kon, MD PhD, Hisashi Tsurumi, MD PhD, Hideki Makishima, MD PhD, Seishi Ogawa, MD PhD

Blood (2019) 134 (Supplement_1): 542.

https://doi.org/10.1182/blood-2019-126444

Published: 2019

Journal Articles

Deconstructing the Clonal Advantage and Clonal Stability of 5q- Candidate Genes in Del(5q) MDS on a Single Cell Level

Ursula S.A. Stalmann, MD, Fabio Ticconi, MSc, Ronghui Li, MSc, Aaron B. Wong, PhD, Glenn Cowley, PhD, David E. Root, PhD, Dirk Heckl, PhD, Inge Snoeren, MSc, Sergio Martinez, PhDMSc, Tim H Brümmendorf, MD, Andreas Schuppert, PhD, Ivan Costa, PhD, Benjamin L. Ebert, MD PhD, Rebekka K. Schneider, MD PhD

Blood (2019) 134 (Supplement_1): 559.

https://doi.org/10.1182/blood-2019-122588

Published: 2019

Journal Articles

Defining Germline Predisposition to Dnmt3a -Mutant Clonal Hematopoiesis (CH)

Logan Sari Schwartz, BS, Kristina Mujica, Rebecca Bell, BA, Matthew Loberg, BA, Jennifer Trowbridge, PhD

Blood (2019) 134 (Supplement_1): 1198.

https://doi.org/10.1182/blood-2019-124530

Published: 2019

Journal Articles

Residual TP53 Mutation Contributes to Chemoresistance through Clonal Expansion in Acute Myeloid Leukemia

Bowen Yan, PhD, Qinwei Chen, MS, Jianfeng Xu, PhD, Wei Li, PhD, Bing Xu, Suming Huang, PhD, Yi Qiu, PhD

Blood (2019) 134 (Supplement_1): 2731.

https://doi.org/10.1182/blood-2019-127511

Published: 2019

Journal Articles

The Genetic Architecture of Myeloproliferative Neoplasms-Blast Phase (MPN-BP) Stem Cells

Xiaoli Wang, MD PhD, Raajit K. Rampal, MD PhD, Cing Siang Hu, Noushin Farnoud, PhD, Christopher Famulare, MS, Minal A Patel, MPH, Erin McGovern, BA, Ronald Hoffman, MD

Blood (2019) 134 (Supplement_1): 1677.

https://doi.org/10.1182/blood-2019-128836

Published: 2019

Journal Articles

T-Cell Clonal Expansion and Activation Associated with Durable Clinical Response to Dual BTK and CDK4/6 Inhibitor Therapy in Mantle Cell Lymphoma

Christina Y. Lee, MD, Maurizio Di Liberto, PhD, Yang Hu, PhD, Xiangao Huang, PhD, Nancy L Bartlett, MD, Kami J. Maddocks, MD, John P. Leonard, MD, Nils-Petter Rudqvist, PhD, Lorenzo Galluzzi, PhD, Peter Martin, FRCPC, MD MS, Olivier Elemento, PhD, Selina Chen-Kiang, PhD

Blood (2019) 134 (Supplement_1): 3973.

https://doi.org/10.1182/blood-2019-122322

Published: 2019

Journal Articles

Microrna-191 Regulates T-Cell Clonal Expansion during Graft-Versus-Host Disease

Chuanfeng Xiong, MD, Wei Huang, MD PhD, Xiaoli Nie, MD PhD, Ying Huang, MD PhD, Yiqun Jiao, MD, Yujing Zou, PhD, Charles Huang, Emilio Feijoo, Dong Pan, PhD, Diana M Cardona, MD, Nelson J. Chao, MD, Qi-jing Li, PhD, Benny J. Chen, MD

Blood (2019) 134 (Supplement_1): 4433.

https://doi.org/10.1182/blood-2019-130179

Published: 2019

Journal Articles

DNMT3A R882 Alters the Epigenome of Hematopoietic Cells

Amanda M Smith, PhD, Taylor LaValle, BS, Shamika Ketkar, PhD, Sai Mukund Ramakrishnan, MS, Christopher A Miller, PhD, Timothy J Ley, MD

Blood (2019) 134 (Supplement_1): 112.

https://doi.org/10.1182/blood-2019-129003

Published: 2019

Journal Articles

IL-1β Secreted from Mutant Cells Carrying JAK2- V617Ffavors Early Clonal Expansion and Promotes MPN Disease Initiation and Progression

Shivam Rai, Nils Hansen, Hui Hao-Shen, Stefan Dirnhofer, Nageswara Rao Tata, Radek C. Skoda

Blood (2019) 134 (Supplement_1): 307.

https://doi.org/10.1182/blood-2019-129800

Published: 2019

Journal Articles

DIS3 Mutation in RUNX1-Mutated AML1 Confers a Highly Dismal Prognosis in AML By Repressing Sister Chromatid Cohesion

Christophe Desterke, PhD, Annelise Bennaceur-Griscelli, MD PhD, Ali G Turhan, MD PhD

Blood (2019) 134 (Supplement_1): 1454.

https://doi.org/10.1182/blood-2019-123352

Published: 2019

Journal Articles

Functionally Distinct Subsets of Monocytes in Mouse and Human Blood

Catherine S Rhee, PhD, Elizabeth W Scadden, Chea L Phillip, Bum-Kyu Lee, PhD, Meeta Mistry, Friedrich F Hoyer, MD, Hiroki Kato, MD PhD, Giovanna Mantica, Jonghwan Kim, PhD, Matthias Nahrendorf, PhD, Michael K Mansour, MD PhD, David B Sykes, MD PhD, David T. Scadden, MD

Blood (2019) 134 (Supplement_1): 438.

https://doi.org/10.1182/blood-2019-124054

Published: 2019

Journal Articles

CRISPR/Cas9 PIG -A gene editing in nonhuman primate model demonstrates no intrinsic clonal expansion of PNH HSPCs

Tae-Hoon Shin, Eun Jung Baek, Marcus A. F. Corat, Shirley Chen, Jean-Yves Metais, Aisha A. AlJanahi, Yifan Zhou, Robert E. Donahue, Kyung-Rok Yu, Cynthia E. Dunbar

Blood (2019) 133 (23): 2542–2545.

https://doi.org/10.1182/blood.2019000800

Published: 2019

Includes: Supplemental data

Journal Articles

The mesenchymal niche in MDS

Eline Pronk, Marc H. G. P. Raaijmakers

Blood (2019) 133 (10): 1031–1038.

https://doi.org/10.1182/blood-2018-10-844639

Published: 2019

Journal Articles

TET2 deficiency leads to stem cell factor–dependent clonal expansion of dysfunctional erythroid progenitors

Blood (2018) 132 (22): 2406–2417.

https://doi.org/10.1182/blood-2018-05-853291

Published: 2018

Includes: Supplemental data

Journal Articles

Tet2 Deficiency in Macrophages Undermines Heart Repair after Infarction

Shaohai Fang, MS, Yang Xiao, PhD, Jia Li, PhD, Tingting Li, MD, Hongxiang Zeng, PhD, Wei Han, MS, Yubin Zhou, PhD, Deqiang Sun, PhD, James M. Martin, MD, Yun Huang, PhD

Blood (2018) 132 (Supplement 1): 2394.

https://doi.org/10.1182/blood-2018-99-115358

Published: 2018

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Genomic and transcriptomic correlates of Richter transformation in chronic lymphocytic leukemia

Therapeutic Applications of a Unique Calcium Channel Blocker to Target SF3B1 MDS

Lncrna Morrbid Regulates Myeloid Cell Survival of AML Driven By a Combination of FLT3ITD and Epigenetic Mutations

Lgr5 Functions As a Critical Negative Regulator of Wnt/β-Catenin Signaling and Is Essential for B-Lymphopoiesis and Malignant B-Cell Transformation

Combined Single Cell Lineage and Transcriptome Sequencing Unveils Cell-Autonomous Regulators of Hematopoietic Stem Cell Fate

Analysis of Mechanisms Underlying Clonal Evolution of AML By a New Single-Cell Sequencing Platform

Deconstructing the Clonal Advantage and Clonal Stability of 5q- Candidate Genes in Del(5q) MDS on a Single Cell Level

Defining Germline Predisposition to Dnmt3a -Mutant Clonal Hematopoiesis (CH)

Residual TP53 Mutation Contributes to Chemoresistance through Clonal Expansion in Acute Myeloid Leukemia

The Genetic Architecture of Myeloproliferative Neoplasms-Blast Phase (MPN-BP) Stem Cells

T-Cell Clonal Expansion and Activation Associated with Durable Clinical Response to Dual BTK and CDK4/6 Inhibitor Therapy in Mantle Cell Lymphoma

Microrna-191 Regulates T-Cell Clonal Expansion during Graft-Versus-Host Disease

DNMT3A R882 Alters the Epigenome of Hematopoietic Cells

IL-1β Secreted from Mutant Cells Carrying JAK2- V617Ffavors Early Clonal Expansion and Promotes MPN Disease Initiation and Progression

DIS3 Mutation in RUNX1-Mutated AML1 Confers a Highly Dismal Prognosis in AML By Repressing Sister Chromatid Cohesion

Functionally Distinct Subsets of Monocytes in Mouse and Human Blood

CRISPR/Cas9 PIG -A gene editing in nonhuman primate model demonstrates no intrinsic clonal expansion of PNH HSPCs

The mesenchymal niche in MDS

TET2 deficiency leads to stem cell factor–dependent clonal expansion of dysfunctional erythroid progenitors

Tet2 Deficiency in Macrophages Undermines Heart Repair after Infarction

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American Society of Hematology

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