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Journal Articles

TET2 Loss Accelerates Leukemogenesis By Disrupting Mismatch Repair Proteins

Blood (2019) 134 (Supplement_1): 1200.

https://doi.org/10.1182/blood-2019-132005

Published: 2019

Journal Articles

Proteomic Analysis of Mitochondrial Membrane Protein FAM210B in Erythroid Cells

Chie Suzuki, Tohru Fujiwara, MD PhD, Hiroki Shima, Koya Ono, MD, Kei Saito, Noriko Fukuhara, MD PhD, Yasushi Onishi, MD PhD, Hisayuki Yokoyama, MD PhD, Shinichi Fujimaki, Yukio Nakamura, MD PhD, Hideo Harigae, MD PhD

Blood (2019) 134 (Supplement_1): 3523.

https://doi.org/10.1182/blood-2019-122618

Published: 2019

Journal Articles

Zinc-Dependent Homomultimerization of Mutant Calreticulin Is Required for MPN Pathogenesis

Jeanne F Rivera, BSc, April Joy Baral, MSc, Rachael Smyth, MSc, Fatima Nadat, PhD, Emma Burman, BSc, Ghadah Alameer, MSc, Sally A Boxall, PhD, Brian R Jackson, PhD, Ann Mullally, MD, Edwin Chen, PhD

Blood (2019) 134 (Supplement_1): 312.

https://doi.org/10.1182/blood-2019-124005

Published: 2019

Journal Articles

Systems Biology Analysis Identifies Targetable Vulnerability Networks to Proteasome Inhibitors in Multiple Myeloma

Mark B. Meads, PhD, Rafael Renatino Canevarolo, PhD, Praneeth Reddy Sudalagunta, PhD, Paula S. Oliveira, Dario M. Magaletti, Bin Fang, PhD, Maria D Coelho Siqueira Silva, MSc, Amit Kulkarni, PhD, Hongyue Dai, PhD, William S. Dalton, PhDMD, Ion Petre, PhD, John M. Koomen, PhD, Ariosto Siqueira Silva, PhD, Kenneth H. Shain, MD PhD

Blood (2018) 132 (Supplement 1): 950.

https://doi.org/10.1182/blood-2018-99-120269

Published: 2018

Journal Articles

Targeting the Glyco-Antigen CD75s with the Tetravalent, Fc-Engineered Antibody 'Ebu-141 Tetra' Induces Potent Killing of B Cell Lymphoma and Plasma Cell Tumors

Katja Klausz, PhD, Amir Karimzadeh-Tabrizi, Malena Buck, Steffen Krohn, Anna-Kathrin Otte, PhD, Christian Kellner, PhD, Giorgio Alberto Croci, MD, Wolfram Klapper, MD, Matthias Peipp, PhD, Martin Gramatzki, MD

Blood (2018) 132 (Supplement 1): 4178.

https://doi.org/10.1182/blood-2018-99-118068

Published: 2018

Journal Articles

Control of Human Hemoglobin Switching By LIN28B-Mediated Regulation of BCL11A Translation

Blood (2018) 132 (Supplement 1): 412.

https://doi.org/10.1182/blood-2018-99-117440

Published: 2018

Journal Articles

Novel Variant Ig Domain (vIgD) Proteins Generated Via Directed Evolution of Igsf Domains Have Therapeutic Efficacy in Animal Models of Graft Versus Host Disease

Steven D Levin, PhD, Lawrence S. Evans, Erika Rickel, Martin F. Wolfson, Stacey R. Dillon, PhD, Michael G. Kornacker, PhD, Ryan Swanson, Stanford L. Peng, MDPhD

Blood (2017) 130 (Supplement 1): 1892.

https://doi.org/10.1182/blood.V130.Suppl_1.1892.1892

Published: 2017

Journal Articles

An Open-Label Study of the Safety and Efficacy of Morotocog Alfa (AF-CC) in Previously Untreated Patients Aged <6 Years in Usual Care Settings

Kaan Kavakli, MD, James Baumann, Francois Pierre Huard, MS, MBA, Lynne Smith, MBA, Christine Alvey, Joan Korth-Bradley, PharmD, PhD, Pablo Rendo, MD, Jeremy Rupon, MD

Blood (2017) 130 (Supplement 1): 1091.

https://doi.org/10.1182/blood.V130.Suppl_1.1091.1091

Published: 2017

Journal Articles

Pharmacokinetics of Subcutaneously Administered Simoctocog Alfa with Von Willebrand Factor Fragment Candidates in a Minipig Model

Barbara A Solecka-Witulska, PhD, Silvio Wuschko, PhD, Christoph Kannicht, PhD

Blood (2017) 130 (Supplement 1): 1073.

https://doi.org/10.1182/blood.V130.Suppl_1.1073.1073

Published: 2017

Journal Articles

TCF3-Hlf Hijacks ERG to Activate Leukemia-Critical Super-Enhancers in t(17;19) Leukemia

Yun Huang, PhD, Brice Mouttet, Hans-Jörg Warnatz, PhD, Maria Pamela Dobay, PhD, Blerim Marovca, Silvia Jenni, PhD, Martin Schrappe, MD PhD, Martin Stanulla, MD PhD, Marie-Laure Yaspo, Beat Bornhauser, PhD, Jean-Pierre Bourquin, MD PhD

Blood (2017) 130 (Supplement 1): 561.

https://doi.org/10.1182/blood.V130.Suppl_1.561.561

Published: 2017

Journal Articles

Aptamer C10.36 Reveals a Ribonucleoprotein Complex on the Surface of Non-Hodgkin Lymphoma Cells Providing Candidates for Multi-Target Therapeutics

Sonal S Tonapi, PhD, Janet Duncan, BA, CCy, Pannu Vaishali, PhD, Matthew Rosenow, PhD, Melissa Richards, BS, Teresa L Tinder, BS, Heather A O'Neill, PhD, Mark R. Miglarese, PhD, David Spetzler, PhD, Michael Famulok, PhD, Günter Mayer, PhD

Blood (2017) 130 (Supplement 1): 3346.

https://doi.org/10.1182/blood.V130.Suppl_1.3346.3346

Published: 2017

Journal Articles

In Situ Capture of the Molecular Composition of Erythroid Transcriptional Enhancers

Jian Xu, PhD

Blood (2017) 130 (Supplement 1): SCI-17.

https://doi.org/10.1182/blood.V130.Suppl_1.SCI-17.SCI-17

Published: 2017

Journal Articles

CD75s Represents a Therapeutic Target for Antibody-Based Immunotherapy of B Cell Lymphoma and Multiple Myeloma

Katja Klausz, PhD, Malena Buck, Steffen Krohn, Renate Burger, PhD, Christian Kellner, PhD, Martin Gramatzki, MD, Matthias Peipp, PhD

Blood (2017) 130 (Supplement 1): 1810.

https://doi.org/10.1182/blood.V130.Suppl_1.1810.1810

Published: 2017

Journal Articles

A Novel Von Willebrand Factor Fragment Acts As a Chaperone to Prolong the Half-Life of Recombinant Human FVIII (Simoctocog Alfa) in Hemophilia a Dogs and FVIII/VWF Double Knockout Mice

Barbara A Solecka-Witulska, PhD, David Lillicrap, MD FRCPC, Christine Hough, PhD, Christoph Kannicht, PhD

Blood (2017) 130 (Supplement 1): 178.

https://doi.org/10.1182/blood.V130.Suppl_1.178.178

Published: 2017

Journal Articles

TET2 and MSH6: A Novel Role for MMR in the Pathogenesis of Myeloid Malignancies

Edward F Greenberg, MD, Cassandra M. Hirsch, BS, Feng Pan, PhD, Babal K Jha, PhD, Yihong Guan, PhD, Valeria Visconte, PhD, Dewen You, PhD, Guangbo Qu, PhD, Amy Graham, Bartlomiej P. Przychodzen, MSc, Thomas Laframboise, PhD, Hideki Makishima, MD PhD, Daniel Gackowski, PhD, Ryszard Ólinski, Professor, Yu-Wei Cheng, PhD, Mikkael A. Sekeres, MD MS, Mingjiang Xu, MDPhD, Jaroslaw P. Maciejewski, PhD MD FACP

Blood (2017) 130 (Supplement 1): 1668.

https://doi.org/10.1182/blood.V130.Suppl_1.1668.1668

Published: 2017

Journal Articles

Ancestral Sequence Reconstruction of Von Willebrand Factor Reveals Highly Conserved Structure/Function

Philip M Zakas, PhD, Caelan Radford, Christine Brown, Courtney Dwyer, RLAT, Christopher B Doering, PhD, Eric A Gaucher, PhD, David Lillicrap, MD FRCPC

Blood (2017) 130 (Supplement 1): 240.

https://doi.org/10.1182/blood.V130.Suppl_1.240.240

Published: 2017

Journal Articles

Integrated Phosphoproteomic and N-Glycoproteomic Landscape of Cutaneous T-Cell Lymphoma Reveals Distinctive Pathogenetic Insights and Therapeutic Vulnerabilities

John Simon Van Arnam, MD MS, Delphine C. M. Rolland, PharmD, PhD, Kojo S. J. Elenitoba-Johnson, MD, Megan S. Lim, MDPhD, Özlem Önder, PhD, Nathanael G. Bailey, MD, David Bahler, MD

Blood (2017) 130 (Supplement 1): 2763.

https://doi.org/10.1182/blood.V130.Suppl_1.2763.2763

Published: 2017

Journal Articles

Identification of Target Pathways of Acquired IMiD and Proteasome Inhibitor Resistance in Multiple Myeloma

Mark B. Meads, PhD, Paula Oliveira, Bin Fang, Praneeth Sudalagunta, PhD, Maria D Coelho Siqueira Silva, MSc, Tuan Nguyen, Allison Distler, Salah-Eddin Komrokji, Aunshka Collins, Hongyue Dai, PhD, John M. Koomen, Ariosto Siqueira Silva, PhD, Kenneth H Shain, MD PhD

Blood (2017) 130 (Supplement 1): 4411.

https://doi.org/10.1182/blood.V130.Suppl_1.4411.4411

Published: 2017

Journal Articles

CAR19 T Cells Redirected to Novel Antigens Mediate Robust Cytotoxicity Against Diverse Malignancies

Paul Rennert, PhD, Christine Ambrose, PhD, Lihe Su, PhD, Fay Dufort, PhD, Lan Wu, PhD, Andreas Hombach, PhD, Hinrich Abken, PhD, Roy Lobb, PhD

Blood (2017) 130 (Supplement 1): 4457.

https://doi.org/10.1182/blood.V130.Suppl_1.4457.4457

Published: 2017

Journal Articles

Nelfinavir Blocks Export of Newly Synthesized Protein from the ER and Interacts with ER-Resident and Mitochondrial Proteins in an Activity-Dependent Fashion

Andrej Besse, Lenka Besse, Sara C. Stolze, Marianne Kraus, Juergen Bader, Herman S Overkleeft, Christoph Driessen, MD

Blood (2017) 130 (Supplement 1): 3074.

https://doi.org/10.1182/blood.V130.Suppl_1.3074.3074

Published: 2017

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TET2 Loss Accelerates Leukemogenesis By Disrupting Mismatch Repair Proteins

Proteomic Analysis of Mitochondrial Membrane Protein FAM210B in Erythroid Cells

Zinc-Dependent Homomultimerization of Mutant Calreticulin Is Required for MPN Pathogenesis

Systems Biology Analysis Identifies Targetable Vulnerability Networks to Proteasome Inhibitors in Multiple Myeloma

Targeting the Glyco-Antigen CD75s with the Tetravalent, Fc-Engineered Antibody 'Ebu-141 Tetra' Induces Potent Killing of B Cell Lymphoma and Plasma Cell Tumors

Control of Human Hemoglobin Switching By LIN28B-Mediated Regulation of BCL11A Translation

Novel Variant Ig Domain (vIgD) Proteins Generated Via Directed Evolution of Igsf Domains Have Therapeutic Efficacy in Animal Models of Graft Versus Host Disease

An Open-Label Study of the Safety and Efficacy of Morotocog Alfa (AF-CC) in Previously Untreated Patients Aged <6 Years in Usual Care Settings

Pharmacokinetics of Subcutaneously Administered Simoctocog Alfa with Von Willebrand Factor Fragment Candidates in a Minipig Model

TCF3-Hlf Hijacks ERG to Activate Leukemia-Critical Super-Enhancers in t(17;19) Leukemia

Aptamer C10.36 Reveals a Ribonucleoprotein Complex on the Surface of Non-Hodgkin Lymphoma Cells Providing Candidates for Multi-Target Therapeutics

In Situ Capture of the Molecular Composition of Erythroid Transcriptional Enhancers

CD75s Represents a Therapeutic Target for Antibody-Based Immunotherapy of B Cell Lymphoma and Multiple Myeloma

A Novel Von Willebrand Factor Fragment Acts As a Chaperone to Prolong the Half-Life of Recombinant Human FVIII (Simoctocog Alfa) in Hemophilia a Dogs and FVIII/VWF Double Knockout Mice

TET2 and MSH6: A Novel Role for MMR in the Pathogenesis of Myeloid Malignancies

Ancestral Sequence Reconstruction of Von Willebrand Factor Reveals Highly Conserved Structure/Function

Integrated Phosphoproteomic and N-Glycoproteomic Landscape of Cutaneous T-Cell Lymphoma Reveals Distinctive Pathogenetic Insights and Therapeutic Vulnerabilities

Identification of Target Pathways of Acquired IMiD and Proteasome Inhibitor Resistance in Multiple Myeloma

CAR19 T Cells Redirected to Novel Antigens Mediate Robust Cytotoxicity Against Diverse Malignancies

Nelfinavir Blocks Export of Newly Synthesized Protein from the ER and Interacts with ER-Resident and Mitochondrial Proteins in an Activity-Dependent Fashion

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