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Journal Articles

Iron-Chelating Potential of Novel Phytochemicals in Poplar and Cedar Trees

Sarah Lane, BSc, Juergen Ehlting, MSc, PhD, Patrick B Walter, MSc, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4806.
https://doi.org/10.1182/blood-2019-127259
Published: 2019
Journal Articles

Integrated Systems Level Examination of Proteasome Inhibitor Stress Recovery in Myeloma Cells Reveals Druggable Vulnerabilities Linked to Multiple Metabolic Processes

Paula Saavedra-Garcia, PhD, Hibah A Al-Sadah, MSc, Lucy Penfold, PhD, Xiaobei Xiong, MRes, Elena Lopez-Jimenez, PhD, Katarzyna Parzych, PhD, Valentina S Caputo, Kevin Blighe, PhD, Martin F. Kaiser, Paolo Piazza, PhD, Vesela Encheva, PhD, Ambrosius P Snijders, PhD, Hector C Keun, DPhil, Diego Oyarzun, PhD, Denise Thiel, MSc, Zijing Liu, PhD, Mauricio Barahona, PhD, Holger W Auner, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1818.
https://doi.org/10.1182/blood-2019-121549
Published: 2019
Journal Articles

Megakaryocyte Reprogramming in Breast Cancer

Harvey G. Roweth, BSc, PhD, Michael Malloy, BS, Gregory Goreczny, BS, PhD, Kelly E. Johnson, BS, PhD, Sandra S. McAllister, PhD, Joseph E. Italiano, Jr., BS, PhD, Elisabeth Battinelli, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 12.
https://doi.org/10.1182/blood-2019-124894
Published: 2019
Journal Articles

Hepcidin, Soluble Transferrin Receptor, and Other Biomarkers of Iron Status Distributions in Healthy 2 Years Old Infants from a National Ambulatory Study in France

Anne-Sylvia Sacri, MD PhD, Thibaud Lefebvre, Pharm D.,PhD, Mariane De Montalembert, MD, Alain Bocquet, MD, Piotr Gembara, MD, Brigitte Pinçant, MD, Serge Hercberg, MD, PhD, Corinne Levy, MD, Amandine Ganon, Pharm D., Laurent Gouya, MD, PhD, Martin Chalumeau, MD, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4809.
https://doi.org/10.1182/blood-2019-128982
Published: 2019
Journal Articles

MetAP2 Inhibition Modifies Hemoglobin S (HbS) to Delay Polymerization and Improve Blood Flow in Sickle Cell Disease

Melanie Demers, PhD, Sarah Sturtevant, BSc, Kevin Guertin, PhD, Dipti Gupta, Kunal Desai, MS, Benjamin Vieira, BS, Alexandra Hicks, PhD, Ayman Ismail, PhD, Yukio Nakamura, MD PhD, Bronner Goncalves, MD PhD, Giuseppe Di Caprio, PhD, Ethan Schonbrun, PhD, Scott Hansen, BS, Martin K. Safo, PhD, David K. Wood, PhD, John M. Higgins, MD PhD, David R. Light, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2260.
https://doi.org/10.1182/blood-2019-128727
Published: 2019
Journal Articles

DNA Cytosine-Demethylating Agent 5-Aza-2'-Deoxycytidine Targets Leukemia Cells through Reducing DNA N 6 -Methyladenine

Xiaochang Liu, PhD, Jiuxia Pang, Christopher Seiler, Ryan Kempen, Hao Liu, Aref Al-Kali, MD, Y. Natalia Tretyakova, Mark Litzow, MD, Shujun Liu
Journal: Blood
Blood (2019) 134 (Supplement_1): 2513.
https://doi.org/10.1182/blood-2019-130490
Published: 2019
Journal Articles

Single Chain Variable Fragment Linker Length Regulates CAR Biology and T Cell Efficacy

Nathan Singh, MD, Noelle V. Frey, MD, Boris Engels, PhD, David M. Barrett, Olga Shestova, PhD, Pranali Ravikumar, MS, Amy Shyu, Steven Highfill, PhD, Linlin Zhao, Liaomin Peng, Brian Granda, Melissa Ramones, Xeuqing Maggie Lu, David A Christian, PhD, Jessica Perazzelli, Simon F Lacey, PhD, Nathan Roy, Janis K Burkhardt, PhD, Florent Colomb, Mohamed Abdel-Mohsen, Regina M Young, PhD, Jennifer Brogdon, PhD, Stephan Grupp, MD PhD, Carl H June, MD, Shannon L. Maude, MD PhD, Saar I. Gill, MD PhD, Marco Ruella, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 247.
https://doi.org/10.1182/blood-2019-131024
Published: 2019
Journal Articles

Inhibition of Anti-Apoptotic Mcl-1 Exerts Anti-Leukemia Activity through Modulation of Leukemia-Stromal Interactions and Metabolic Functions in AML

Bing Z Carter, PhD, Po Yee Mak, Marc Warmoes, Wenjing Tao, Philip Lorenzi, Vivian Ruvolo, MS, Lin Tan, Justin Cidado, PhD, Lisa Drew, PhD, Michael Andreeff, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3727.
https://doi.org/10.1182/blood-2019-124453
Published: 2019
Journal Articles

The PRIME Trial: PARP Inhibition in IDH Mutant Effectiveness Trial. a Phase II Study of Olaparib in Isocitrate Dehydrogenase (IDH) Mutant Relapsed/Refractory Acute Myeloid Leukemia and Myelodysplastic Syndrome

Namrata S Chandhok, MD, Wei Wei, MD PhD, Ranjit Bindra, MD PhD, Stephanie Halene, MD, Yu Shyr, Jing Li, PhD, Michael Berens, PhD, Chris Karlovich, PhD, S. Percy Ivy, MD, Thomas Prebet, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3909.
https://doi.org/10.1182/blood-2019-129168
Published: 2019
Journal Articles

Excess Serine from the Microenvironment Caused the Impaired Megakaryopoiesis and Thrombocytopia in Multiple Myeloma

Chunmei Kuang, Meijuan Xia, Gang An, MD, Cuicui Liu, Dan Wu, Pei Su, Jingyu Zhang, Jiliang Xia, PhD, Jiaojiao Guo, Xuan Wu, Wei Jia, PhD, Lugui Qiu, MD PhD, Wen Zhou, PhD, Jiaxi Zhou
Journal: Blood
Blood (2019) 134 (Supplement_1): 4331.
https://doi.org/10.1182/blood-2019-125289
Published: 2019
Journal Articles

Differential Metabolomics and Lipidomics of Hypoxic/Hypocapnic Long-Term Stored Red Cells Associate with Improved 24-Hour Recovery after Transfusion

Tatsuro Yoshida, PhD, Angelo D'Alessandro, PhD, Xiaoyun Fu, PhD, Travis Nemkov, PhD, Davide Stefanoni, Michael Dioguardi, BS, Neeta Rugg, Shawnagay Nestheide, BS, William Iselin, BA, Andrew Dunham, PhD, James C. Zimring, MD PhD, Jose A Cancelas, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4994.
https://doi.org/10.1182/blood-2019-125961
Published: 2019
Journal Articles

Hypovitaminosis D Is Prevalent in Patients with Renal AL Amyloidosis and Associated with Non-t(11;14)

Eli Muchtar, MD, Matthew T. Drake, MD PhD, Angela Dispenzieri, MD, Martha Q. Lacy, MD, Francis K. Buadi, MB, CHB, David Dingli, MD PhD, Suzanne R. Hayman, MD, Prashant Kapoor, MD, Nelson Leung, MD, Dragan Jevremovic, MD PhD, Amie Fonder, PA-C, MS, Miriam A. Hobbs, APRN, CNP, DNP, Yi L. Hwa, APRN, CNP, DNP, Wilson I Gonsalves, MD, Rahma M Warsame, MD, Taxiarchis Kourelis, MD, Stephen J Russell, MD PhD, John A. Lust, MD PhD, Ronald S. Go, MD, Robert A. Kyle, MD, S. Vincent Rajkumar, MD, Shaji K. Kumar, MD, Morie A Gertz, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5523.
https://doi.org/10.1182/blood-2019-127668
Published: 2019
Journal Articles

Evaluation of a Blood Coagulation Factor IX Variant That Functions Independently of Factor VIII As an Alternative Treatment for Hemophilia A

Viola J.F. Strijbis, MSc, Ka Lei Cheung, Pavlina Konstantinova, PhD, Ying Poi Liu, PhD, Sander J van Deventer, MD PhD, Mettine H.A. Bos, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1110.
https://doi.org/10.1182/blood-2019-124120
Published: 2019
Journal Articles

Adenylate Kinase 2 Links Energy Metabolism and Cell Fate in Hematopoietic Stem and Progenitor Cells

Wenqing Wang, PhD, Avni Awani, PhD, Andrew Devilbiss, PhD, Thomas Mathews, PhD, Daniel Thomas, MD PhD, Daniel P. Dever, PhD, Matthew Porteus, MD PhD, Sean Morrison, PhD, Katja G Weinacht, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3705.
https://doi.org/10.1182/blood-2019-129424
Published: 2019
Journal Articles

Integrated Multi-Level Omics to Characterize Bortezomib Resistance in Multiple Myeloma

David C. Koomen, BS, Mark B. Meads, PhD, Dario M. Magaletti, Joy D. Guingab, PhD, Paula S. Oliveira, Bin Fang, PhD, Victoria Izumi, MS, Rafael Renatino-Canevarolo, PhD, Praneeth Reddy Sudalagunta, PhD, Maria Silva, Raghunandanreddy Alugubelli, MS, Gabe De Avilla, Alex Tungeskiv, Eric A. Welsh, PhD, Laurel E. Meke, Wei Zhang, PhD, Steven A. Eschrich, PhD, Timothy J. Garrett, PhD, Ariosto Siqueira Silva, PhD, John M. Koomen, PhD, Kenneth H. Shain, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5534.
https://doi.org/10.1182/blood-2019-132001
Published: 2019
Journal Articles

High Glycine Promotes Proliferation and Progression Though Increase of Glutathione Synthesis in Multiple Myeloma

Jiliang Xia, PhD, Jingyu Zhang, Bin Meng, Xuan Wu, Qian Lei, Yinghong Zhu, Yanjuan He, MD, Lugui Qiu, MD PhD, Wei Jia, PhD, Wen Zhou, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1791.
https://doi.org/10.1182/blood-2019-125452
Published: 2019
Journal Articles

Resolvin D4 attenuates the severity of pathological thrombosis in mice

Deya Cherpokova, Charlotte C. Jouvene, Stephania Libreros, Elise P. DeRoo, Long Chu, Xavier de la Rosa, Paul C. Norris, Denisa D. Wagner, Charles N. Serhan
Journal: Blood
Blood (2019) 134 (17): 1458–1468.
https://doi.org/10.1182/blood.2018886317
Published: 2019
Includes: Supplemental data
Journal Articles

Autocrine LTA signaling drives NF-κB and JAK-STAT activity and myeloid gene expression in Hodgkin lymphoma

Brief Report
Linda von Hoff, Eva Kärgel, Vedran Franke, Erik McShane, Kathrin W. Schulz-Beiss, Giannino Patone, Nikolai Schleussner, Marina Kolesnichenko, Norbert Hübner, Oliver Daumke, Matthias Selbach, Altuna Akalin, Stephan Mathas, Claus Scheidereit
Journal: Blood
Blood (2019) 133 (13): 1489–1494.
https://doi.org/10.1182/blood-2018-08-871293
Published: 2019
Includes: Supplemental data
Journal Articles

Potential Metabolite Markers of Multiple Myeloma

Jiliang Xia, PhD, Jingyu Zhang, Xuan Wu, ShiLian Chen, Jingchao Lin, Mingming Su, Jiaojiao Guo, Yongjun Guan, Minghua Wu, Lugui Qiu, MD, Fenghuang Zhan, MD, Wen Zhou, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3163.
https://doi.org/10.1182/blood-2018-99-115934
Published: 2018
Journal Articles

Sumoylation of Pyruvate Kinase M2 Inhibits Myeloid Differentiation in Hematopoietic Cells

Li Xia, PhD, Xin-Ran Wang, MA, Ran Wei, BA, Jin-Song Yan, MD PhD, Guo-Qiang Chen, PhD, Ying Lu, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3919.
https://doi.org/10.1182/blood-2018-99-117899
Published: 2018