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Journal Articles

Identification of FASN-Dependent Onco-Metabolic Regulation of the Pentose Phosphate Pathway (PPP) and Nucleotide Metabolism in Non-Hodgkin Lymphoma (NHL)

Ravi Dashnamoorthy, PhD, Afshin Beheshti, PhD, Xiaoyang Su, PhD, Ying Chen, PhD, Maisarah Mokhtar, B.S, Gregory Dolnikowski, Frederick Lansigan, MD, William B Kinlaw, III, MD, Sandeep Dave, MD, Andrew M. Evens, DO, MSc

Blood (2019) 134 (Supplement_1): 1573.

https://doi.org/10.1182/blood-2019-126382

Published: 2019

Journal Articles

Cyclin D1 Driven CDK4 Activity Is Responsible for Hypersensitivity to NOXA Inducing Combination Treatment in Mantle Cell Lymphoma (MCL) Cells

Simon Heine, MSc, Elisabeth Silkenstedt, MD, Michael A Dengler, PhD, Kleih Markus, MSc, German Ott, MD, Neus Giménez Carabaza, B.Pharm, Colomer Dolors, PhD, Heiko van der Kuip, PhD, Walter E. Aulitzky, MD

Blood (2017) 130 (Supplement 1): 2811.

https://doi.org/10.1182/blood.V130.Suppl_1.2811.2811

Published: 2017

Journal Articles

Lipid Addiction of Diffuse Large B-Cell Lymphoma (DLBCL): Fatty Acid Synthase (FASN) and PI3K Dependent Cell Death Identifies a Novel Therapeutic Paradigm

Ravi Dashnamoorthy, PhD, Afshin Beheshti, PhD, Nassera Abermil, MS, PharmD, Frederick Lansigan, MD, William Kinlaw, MD, Ron Gartenhaus, MD, Graham Jones, PhD DSc, Lynn Hlatky, PhD, Andrew M. Evens, DO, MSc

Blood (2015) 126 (23): 1284.

https://doi.org/10.1182/blood.V126.23.1284.1284

Published: 2015

Journal Articles

The Lipid Addiction of Diffuse Large B-Cell Lymphoma (DLBCL) and Potential Treatment Strategies with Novel Fatty Acid Synthase (FASN) Small Molecule Inhibitors

Ravi Dashnamoorthy, PhD, Nassera Abermil, MS, PharmD, Afshin Behesti, PhD, Paige Kozlowski, BS, Frederick Lansigan, MD, William B Kinlaw, MD, Ronald Gartenhaus, MD, Graham Jones, PhD DSc, Lynn Hlatky, PhD, Andrew M. Evens, DO, MSc

Blood (2014) 124 (21): 4490.

https://doi.org/10.1182/blood.V124.21.4490.4490

Published: 2014

Journal Articles

Targeting The Interactions Of Fatty Acid Metabolism With PI3K/mTOR and MAPK As a Novel Therapeutic Strategy In Diffuse Large B-Cell Lymphoma (DLBCL)

Ravi Dashnamoorthy, PhD, Frederick Lansigan, MD, Wilson L Davis, III, B.S., William B Kinlaw, III, MD, Ronald Gartenhaus, Andrew M Evens, DO, MSc

Blood (2013) 122 (21): 5133.

https://doi.org/10.1182/blood.V122.21.5133.5133

Published: 2013

Journal Articles

Diffuse Large B-Cell Lymphomas Utilize Endogenous and Exogenous Fatty Acids for Cell Growth and Survival

Frederick Lansigan, MD, Wilson L Davis, III, B.S., Nancy Kuemmerle, DO, PhD, Leslie E Lupien, B.A., Valeriya Posternak, B.S., Prabhjot Kaur, MD, Nicole C Smits, Ph.D., B.S.C., Ravi Dashnamoorthy, Ph.D., Andrew M. Evens, DO, MSc, William B Kinlaw, III, MD

Blood (2012) 120 (21): 1581.

https://doi.org/10.1182/blood.V120.21.1581.1581

Published: 2012

Journal Articles

Fatty Acid Metabolism in Diffuse Large B-Cell Lymphoma (DLBCL): Interaction with Oncogenic Cell Signaling Pathways and the Identification of a Novel Treatment Paradigm.

Ravi Dashnamoorthy, Ph.D., Frederick Lansigan, MD, Wilson L Davis, III, B.S., Nancy Kuemmerle, DO, PhD, William B Kinlaw, III, MD, Andrew M. Evens, DO, MSc

Blood (2012) 120 (21): 2711.

https://doi.org/10.1182/blood.V120.21.2711.2711

Published: 2012

Journal Articles

Involvement of Lipogenic Pathway In 5-Azacytidine-Induced Cytotoxicity In Waldenstrom's Macroglobulinemia

Lian Xu, Christopher Patterson, Jenny Sun, MD, Guang Yang, MD, Yangsheng Zhou, MD, Zachary Hunter, Bryan Ciccarelli, Robert Manning, Xia Liu, MD, Yang Cao, MD, Hsiuyi Tseng, Leukothea Ioakimidis, Christina Hanzis, Steven P. Treon, MD, PhD

Blood (2010) 116 (21): 2991.

https://doi.org/10.1182/blood.V116.21.2991.2991

Published: 2010

Journal Articles

Involvement of Fatty Acid Synthase in Azacytidine-Induced Cytotoxicity in Waldenstrom's Macroglobulinemia.

Lian Xu, Christopher J Patterson, Jenny Sun, MD, Guang Yang, PhD, Yangsheng Zhou, MD, PhD, Zachary Hunter, Evdoxia Hatjiharissi, MD, Bryan Ciccarelli, Ping Gong, Xia Liu, Hsiuyi Tseng, Thea Ioakimidis, MS, Robert Manning, Christina Hanzis, Yang Cao, Megan Lewicki, Steven Treon, MD, PhD

Blood (2009) 114 (22): 3731.

https://doi.org/10.1182/blood.V114.22.3731.3731

Published: 2009

Journal Articles

Increased Fatty Acid Synthase Is a Therapeutic Target in Multiple Myeloma.

Weiqin Wang, PhD, Xiaoying Zhao, MD, Haiyan Wang, Gengbo Xu, Xiaohong Zhang

Blood (2006) 108 (11): 5084.

https://doi.org/10.1182/blood.V108.11.5084.5084

Published: 2006

Journal Articles

Molecular Phenotype of Malignant CD34+ Hematopoietic Stem and Progenitor Cells in Chronic Myelogenous Leukemia.

Ralf Kronenwett, MD, Elena Diaz-Blanco, Thorsten Graef, MD, Ulrich Steidl, MD, Slawomir Kliszewski, Ingmar Bruns, Frank Neumann, MD, Simone Bork, Ulf Butterweck, Nicole Roes, Benedikt Brors, PhD, Roland Eils, PhD, Guido Kobbe, MD, Norbert Gattermann, MD, Rainer Haas, MD

Blood (2005) 106 (11): 2863.

https://doi.org/10.1182/blood.V106.11.2863.2863

Published: 2005

Journal Articles

Protein Palmitoylation in Platelet Function: Role in G Protein-Mediated Platelet Activation and Platelet Recruitment into Thrombi.

Robert Flaumenhaft, MD, PhD, James R. Dilks, Derek S. Sim, PhD

Blood (2005) 106 (11): 650.

https://doi.org/10.1182/blood.V106.11.650.650

Published: 2005

Journal Articles

Fatty Acid Synthase Inhibitor Induces Apoptosis and Inhibits Proliferation in Multiple Myeloma Cells.

Weiqin Wang, Dong Wu

Blood (2004) 104 (11): 4849.

https://doi.org/10.1182/blood.V104.11.4849.4849

Published: 2004

NARROW

Identification of FASN-Dependent Onco-Metabolic Regulation of the Pentose Phosphate Pathway (PPP) and Nucleotide Metabolism in Non-Hodgkin Lymphoma (NHL)

Cyclin D1 Driven CDK4 Activity Is Responsible for Hypersensitivity to NOXA Inducing Combination Treatment in Mantle Cell Lymphoma (MCL) Cells

Lipid Addiction of Diffuse Large B-Cell Lymphoma (DLBCL): Fatty Acid Synthase (FASN) and PI3K Dependent Cell Death Identifies a Novel Therapeutic Paradigm

The Lipid Addiction of Diffuse Large B-Cell Lymphoma (DLBCL) and Potential Treatment Strategies with Novel Fatty Acid Synthase (FASN) Small Molecule Inhibitors

Targeting The Interactions Of Fatty Acid Metabolism With PI3K/mTOR and MAPK As a Novel Therapeutic Strategy In Diffuse Large B-Cell Lymphoma (DLBCL)

Diffuse Large B-Cell Lymphomas Utilize Endogenous and Exogenous Fatty Acids for Cell Growth and Survival

Fatty Acid Metabolism in Diffuse Large B-Cell Lymphoma (DLBCL): Interaction with Oncogenic Cell Signaling Pathways and the Identification of a Novel Treatment Paradigm.

Involvement of Lipogenic Pathway In 5-Azacytidine-Induced Cytotoxicity In Waldenstrom's Macroglobulinemia

Involvement of Fatty Acid Synthase in Azacytidine-Induced Cytotoxicity in Waldenstrom's Macroglobulinemia.

Increased Fatty Acid Synthase Is a Therapeutic Target in Multiple Myeloma.

Molecular Phenotype of Malignant CD34+ Hematopoietic Stem and Progenitor Cells in Chronic Myelogenous Leukemia.

Protein Palmitoylation in Platelet Function: Role in G Protein-Mediated Platelet Activation and Platelet Recruitment into Thrombi.

Fatty Acid Synthase Inhibitor Induces Apoptosis and Inhibits Proliferation in Multiple Myeloma Cells.

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American Society of Hematology

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American Society of Hematology

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