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Journal Articles

Glucocorticoids Induce the Maintenance and Expansion of an Immature CFU-E Erythroid Progenitor Population in Humans

Ryan Ashley, BS, MS, Hongxia Yan, MS, Nan Wang, PhD, John Hale, PhD, Brian M Dulmovits, MS, Julien Papoin, MS, Meagan Olive, Namrata Udeshi, PhD, Steven Carr, PhD, Adrianna Vlachos, MD, Jeffrey Michael M Lipton, MD PhD, Lydie M. Da Costa, MD PhD, Christopher D. Hillyer, MD, Sandrina Kinet, PhD, Naomi Taylor, MD PhD, Mohandas Narla, DSc, Anupama Narla, MD, Lionel Blanc, PhD

Blood (2019) 134 (Supplement_1): 943.

https://doi.org/10.1182/blood-2019-130710

Published: 2019

Journal Articles

Single-Cell RNA-Seq Identifies Potentially Pathogenic B Cell Populations That Uniquely Circulate in Patients with Chronic Gvhd

Jonathan C Poe, PhD, Dadong Zhang, PhD, Jichun Xie, PhD, Rachel A. DiCioccio, BS, Xiaodi Qin, MS, Jiyuan Fang, MS, Vincent T. Ho, MD, Jeremy J. Rose, MS, Steven Z. Pavletic, MD MS, Frances T. Hakim, PhD, Wei Jia, MD PhD, Amy N. Suthers, PhD, Mitchell E. Horwitz, MD, David A. Rizzieri, MD, William C. McManigle, MD, Nelson J. Chao, MD, Kouros Owzar, PhD, Stefanie Sarantopoulos, MD PhD

Blood (2019) 134 (Supplement_1): 874.

https://doi.org/10.1182/blood-2019-130928

Published: 2019

Journal Articles

Metformin Suppress Cellular and Molecular Processes Related to Maintenance and Proliferation of Myeloproliferative Neoplasm Stem Cell

Juan L Coelho-Silva, BSc, MSc, Thiago Mantello Bianco, MSc, Antonio Bruno Alves Silva, BSc, Diego Antonio Pereira-Martins, M.Sc., Natasha Peixoto Fonseca, B.Sc., M.Sc., Isabel Weinhäuser, MSc, Eduardo M Rego, MD PhD, Fernando Chahud, MD PhD, João Agostinho Machado-Neto, PhD, Lorena Lobo Figueiredo-Pontes, MD PhD, Fabiola Traina, MD PhD

Blood (2019) 134 (Supplement_1): 1682.

https://doi.org/10.1182/blood-2019-132115

Published: 2019

Journal Articles

Hotspot U2AF1 Mutations Determine Missplicing Selectivity: Novel Mechanisms Altering Splicing Factors

Vera Adema, PhD, Courtney E Hershberger, BS, Wencke Walter, PhD, Cassandra M Kerr, MS, Stephan Hutter, PhD, Yasunobu Nagata, MD PhD, Hassan Awada, Sunisa Kongkiatkamon, Christina Snider, Milo Co, Manja Meggendorfer, PhD, Aziz Nazha, MD, Hetty E. Carraway, MD MBA, Mikkael A. Sekeres, MD MS, Francesc Sole, PhD, Richard A Padgett, PhD, Torsten Haferlach, MD, Jaroslaw P. Maciejewski, MD PhD, Valeria Visconte, PhD

Blood (2019) 134 (Supplement_1): 2985.

https://doi.org/10.1182/blood-2019-129367

Published: 2019

Journal Articles

CRISPR/Cas9-Targeted De Novo DNA Methylation Is Maintained and Impacts the Colony Forming Potential of Human Hematopoietic CD34 + Cells

Emily A Saunderson, PhDBSc, Kevin Rouault-Pierre, PhDBSc, John G. Gribben, MD DSc, Gabriella Ficz, PhDBSc

Blood (2019) 134 (Supplement_1): 2517.

https://doi.org/10.1182/blood-2019-130267

Published: 2019

Journal Articles

Replication Stress Response and CDKN1A Engagement Constrain Fetal Hematopoietic Stem Cell Pool Size in Fanconi Anemia

Makiko Mochizuki-Kashio, PhD, Young Me Yoon, Theresa N Menna, BS, Markus Grompe, MD, Peter Kurre, MD

Blood (2019) 134 (Supplement_1): 107.

https://doi.org/10.1182/blood-2019-125669

Published: 2019

Journal Articles

Selinexor, Pomalidomide, and Dexamethasone (SPd) in Patients with Relapsed or Refractory Multiple Myeloma

Blood (2019) 134 (Supplement_1): 141.

https://doi.org/10.1182/blood-2019-122907

Published: 2019

Journal Articles

Pharmacological Inhibition of MAP2K7 Induces Apoptosis and Cell Cycle Arrest in T-Cell Acute Lymphoblastic Leukemia

Taylor J Chen, BS, Ye Shen, PhD, Cory Seth Bridges, BS, Chun Shik Park, PhD, Jacob J. Junco, PhD, Karen R. Rabin, MD PhD, H. Daniel Lacorazza, PhD

Blood (2019) 134 (Supplement_1): 3889.

https://doi.org/10.1182/blood-2019-129127

Published: 2019

Journal Articles

Combination of CYC065, a Second Generation CDK2/9 Inhibitor, with Venetoclax or Standard Chemotherapies - a Novel Therapeutic Approach for Acute Myeloid Leukaemia (AML)

Wittawat Chantkran, MD MSc, Daniella Zheleva, PhD, Sheelagh Frame, PhD, Ya-Ching Hsieh, PhD, Mhairi Copland, PhD MBBChir, FRCP, FRCPath

Blood (2019) 134 (Supplement_1): 3938.

https://doi.org/10.1182/blood-2019-124072

Published: 2019

Journal Articles

Fibrinogen Activates FAK to Promote the Colorectal Adenocarcinoma Growth

Balkrishan Sharma, PhD, Duaa Mureb, BS, Sumit Murab, PhD, Leah A. Rosenfeldt, BS, Brenton J Francisco, MD, Alexander A Boucher, MD, Rachel Cantrell, BS, Jacob Mast, Matthew J. Flick, PhD, Patrick W Whitlock, MD, Joseph S. Palumbo, MD

Blood (2019) 134 (Supplement_1): 1111.

https://doi.org/10.1182/blood-2019-130497

Published: 2019

Journal Articles

A CRISPR/Cas9-Generated Murine Model Reveals Cooperation between BCR Signaling and CDKN2A/2B and TP53 Disruption in Richter Syndrome

Supriya Chakraborty, PhD, Ilaria Fortunati, BS, Claudio Martines, MS, Brijesh Yadav, PhD, Marija Dimishkovska, PhD, Idanna Innocenti, MD PhD, Rosa Fazio, BS, Giovanni D'Arena, MD, Aleksandar Dimovski, MD PhD, Luca Laurenti, MD, Dimitar G Efremov, MD PhD

Blood (2019) 134 (Supplement_1): 4278.

https://doi.org/10.1182/blood-2019-128425

Published: 2019

Journal Articles

Response to Therapy and the Effectiveness of Treatment with Selinexor and Dexamethasone in Patients with Penta-Exposed Triple-Class Refractory Myeloma Who Had Plasmacytomas

Blood (2019) 134 (Supplement_1): 3140.

https://doi.org/10.1182/blood-2019-129038

Published: 2019

Journal Articles

Microrna-126 Levels Modulate B-ALL Aggressiveness but Require Tight Regulation to Guarantee Disease Maintenance

Carolina Caserta, Silvia Nucera, MD, Matteo Maria Naldini, Nadia Foligno, Giacomo Desantis, PhD, Fabio Ciceri, MD, Davide Cittaro, PhD, Bernhard Gentner, MD

Blood (2018) 132 (Supplement 1): 2834.

https://doi.org/10.1182/blood-2018-99-115101

Published: 2018

Journal Articles

Pharmacologic Targeting of LIN28/Let-7 in Acute Myeloid Leukemia

Martina M Roos, PhD PharmD, Michelle Li, Pang Amara, John P Chute, MD

Blood (2018) 132 (Supplement 1): 4072.

https://doi.org/10.1182/blood-2018-99-119982

Published: 2018

Journal Articles

Dexamethasone Accelerates the Transition of Human BFU-E to CFU-E and Enhances CFU-E Proliferation through Cell Cycle Regulation

Ryan Ashley, BS, MS, Hongxia Yan, MS, Brian Dulmovits, BA, MS, Nan Wang, PhD, Julien Papoin, MS, Jeffrey M Lipton, MD PhD, Mohandas Narla, DSc, Anupama Narla, MD, Lionel Blanc, PhD

Blood (2018) 132 (Supplement 1): 3620.

https://doi.org/10.1182/blood-2018-99-116596

Published: 2018

Journal Articles

Disruption of NOTCH1-MYC-CD44 Axis Targets Leukemia Initiating Cells (LIC) in T-ALL

Sujan Piya, PhD, Seemana Bhattacharya, PhD, Hong Mu, MD PhD, Vivian Ruvolo, MS, Natalia Baran, PhDMD, Teresa McQueen, MS, R. Eric Davis, MD, Yimin Qian, PhD, Kanak Raina, PhD, M. James You, MD PhD, Marina Y. Konopleva, MD PhD, Hagop M. Kantarjian, MD, Michael Andreeff, MD PhD, Gautam Borthakur, MD

Blood (2018) 132 (Supplement 1): 890.

https://doi.org/10.1182/blood-2018-99-115692

Published: 2018

Journal Articles

AXL Expression in Pediatric AML Is Associated with Putative LSC and Correlates with a Distinct Set of Proteins Associated with Cell Metabolism, Cell Cycle, and Unfolded Protein Response

Fieke W Hoff, BSc, Peter P. Ruvolo, PhD, Yihua Qiu, Michael Andreeff, MD PhD, Eveline S. de Bont, MD, Terzah M. Horton, MD PhD, Steven M. Kornblau, MD

Blood (2018) 132 (Supplement 1): 2686.

https://doi.org/10.1182/blood-2018-99-112555

Published: 2018

Journal Articles

TAM Inhibitor ONO-7475 Combination with Sorafenib Is Effective Using in Vitro and In Vivo Models of FLT3 ITD Acute Myeloid Leukemia

Peter P. Ruvolo, PhD, Huaxian Ma, MS, Vivian Ruvolo, MS, Xiaorui Zhang, BS, Hong Mu, MD PhD, Tomoko Yasuhiro, Kohei Tanaka, Toshio Yoshizawa, PhD, Weiguo Zhang, MD PhD, Jorge E. Cortes, MD, Michael Andreeff, MD PhD, Sean M Post, PhD

Blood (2018) 132 (Supplement 1): 2642.

https://doi.org/10.1182/blood-2018-99-112211

Published: 2018

Journal Articles

In Vivo Modeling of Clonal Competition Using CRISPR-Based Gene Editing Reveals Novel Fitness Variables in Multiple Myeloma

Yujia Shen, PhD, Salomon Manier, MD PhD, Sabrin Tahri, MD, Brianna Berrios, BS, Oksana Zavidij, PhD, Jihye Park, PhD, Romanos Pistofidis, MD, Irene M. Ghobrial, MD

Blood (2018) 132 (Supplement 1): 57.

https://doi.org/10.1182/blood-2018-99-113842

Published: 2018

Journal Articles

Selinexor Plus Pomalidomide and Low Dose Dexamethasone (SPd) in Patients with Relapsed or Refractory Multiple Myeloma

Christine I Chen, MD, Heather J. Sutherland, MD PhD, Rami Kotb, MD, Michael Sebag, MD PhD, Darrell J. White, MD, William Bensinger, MD, Cristina J Gasparetto, MD, Richard Leblanc, MDFRCPC, Christopher P. Venner, MD FRCPC, Suzanne Lentzsch, MD, Gary J. Schiller, MD, Brea Lipe, MD, Aldo Del Col, Jatin J. Shah, MD, Jacqueline Jeha, Jean-Richard Saint-Martin, Michael G. Kauffman, MD PhD, Sharon Shacham, PhD MBA, Nizar Bahlis, MD

Blood (2018) 132 (Supplement 1): 1993.

https://doi.org/10.1182/blood-2018-99-117349

Published: 2018

NARROW

Glucocorticoids Induce the Maintenance and Expansion of an Immature CFU-E Erythroid Progenitor Population in Humans

Single-Cell RNA-Seq Identifies Potentially Pathogenic B Cell Populations That Uniquely Circulate in Patients with Chronic Gvhd

Metformin Suppress Cellular and Molecular Processes Related to Maintenance and Proliferation of Myeloproliferative Neoplasm Stem Cell

Hotspot U2AF1 Mutations Determine Missplicing Selectivity: Novel Mechanisms Altering Splicing Factors

CRISPR/Cas9-Targeted De Novo DNA Methylation Is Maintained and Impacts the Colony Forming Potential of Human Hematopoietic CD34 + Cells

Replication Stress Response and CDKN1A Engagement Constrain Fetal Hematopoietic Stem Cell Pool Size in Fanconi Anemia

Selinexor, Pomalidomide, and Dexamethasone (SPd) in Patients with Relapsed or Refractory Multiple Myeloma

Pharmacological Inhibition of MAP2K7 Induces Apoptosis and Cell Cycle Arrest in T-Cell Acute Lymphoblastic Leukemia

Combination of CYC065, a Second Generation CDK2/9 Inhibitor, with Venetoclax or Standard Chemotherapies - a Novel Therapeutic Approach for Acute Myeloid Leukaemia (AML)

Fibrinogen Activates FAK to Promote the Colorectal Adenocarcinoma Growth

A CRISPR/Cas9-Generated Murine Model Reveals Cooperation between BCR Signaling and CDKN2A/2B and TP53 Disruption in Richter Syndrome

Response to Therapy and the Effectiveness of Treatment with Selinexor and Dexamethasone in Patients with Penta-Exposed Triple-Class Refractory Myeloma Who Had Plasmacytomas

Microrna-126 Levels Modulate B-ALL Aggressiveness but Require Tight Regulation to Guarantee Disease Maintenance

Pharmacologic Targeting of LIN28/Let-7 in Acute Myeloid Leukemia

Dexamethasone Accelerates the Transition of Human BFU-E to CFU-E and Enhances CFU-E Proliferation through Cell Cycle Regulation

Disruption of NOTCH1-MYC-CD44 Axis Targets Leukemia Initiating Cells (LIC) in T-ALL

AXL Expression in Pediatric AML Is Associated with Putative LSC and Correlates with a Distinct Set of Proteins Associated with Cell Metabolism, Cell Cycle, and Unfolded Protein Response

TAM Inhibitor ONO-7475 Combination with Sorafenib Is Effective Using in Vitro and In Vivo Models of FLT3 ITD Acute Myeloid Leukemia

In Vivo Modeling of Clonal Competition Using CRISPR-Based Gene Editing Reveals Novel Fitness Variables in Multiple Myeloma

Selinexor Plus Pomalidomide and Low Dose Dexamethasone (SPd) in Patients with Relapsed or Refractory Multiple Myeloma

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American Society of Hematology

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American Society of Hematology

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