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Journal Articles

A prospective, blinded study of a PF4-dependent assay for HIT diagnosis

Bethany Samuelson Bannow, Deepti M. Warad, Curtis G. Jones, Shannon M. Pechauer, Brian R. Curtis, Daniel W. Bougie, Ruchika Sharma, Diane E. Grill, Mary W. Redman, Parisa R. Khalighi, Rachel R. Leger, Rajiv K. Pruthi, Dong Chen, Daniel E. Sabath, Richard H. Aster, David A. Garcia, Anand Padmanabhan

Blood (2021) 137 (8): 1082–1089.

https://doi.org/10.1182/blood.2020008195

Published: 2021

Includes: Supplemental data

Journal Articles

Targeted Delivery of Nanocarrier-Conjugated Doxorubicin to Widen the Therapeutic Window of the Most Active Drug in Lymphoma Therapeutics

Artavazd Arumov, BSc, Piumi Y. Liyanage, BS, Asaad Trabolsi, MD, Lingxiao Li, PhD, Evan R. Roberts, BS, Daniel Bilbao, PhD, Roger M. LeBlanc, PhD, Jonathan H. Schatz, MD

Blood (2019) 134 (Supplement_1): 4061.

https://doi.org/10.1182/blood-2019-122599

Published: 2019

Journal Articles

Epigenetic Activation of the pH Regulator MCT4 in Acute Myeloid Leukemia Exploits a Fundamental Metabolic Process of Enhancing Cell Growth through Proton Shifting

Cheuk-Him Man, David T. Scadden, MD, Francois Mercier, MD FRCPC, Nian Liu, Wentao Dong, Gregory Stephanopoulos, PhD, Li Jiang, PhD, Yookyung Jung, PhD, Charles Lin, PhD, Anskar Y.-H. Leung, MD PhD

Blood (2019) 134 (Supplement_1): 3765.

https://doi.org/10.1182/blood-2019-123604

Published: 2019

Journal Articles

The Distinctive Metabolic Environment of the Bone Marrow Niche Drives Leukemia Chemoresistance

Nick van Gastel, PhD, Jessica B. Spinelli, PhD, Azeem Sharda, MS, Amir Schajnovitz, PhD, Ninib Baryawno, PhD, Catherine S Rhee, PhD, Toshihiko Oki, MD PhD, Eliane Grace, Heather J. Soled, Charles Vidoudez, PhD, Sunia A. Trauger, PhD, Marcia C. Haigis, PhD, David T. Scadden, MD

Blood (2019) 134 (Supplement_1): 3725.

https://doi.org/10.1182/blood-2019-124789

Published: 2019

Journal Articles

Inhibition of Anti-Apoptotic Mcl-1 Exerts Anti-Leukemia Activity through Modulation of Leukemia-Stromal Interactions and Metabolic Functions in AML

Bing Z Carter, PhD, Po Yee Mak, Marc Warmoes, Wenjing Tao, Philip Lorenzi, Vivian Ruvolo, MS, Lin Tan, Justin Cidado, PhD, Lisa Drew, PhD, Michael Andreeff, MD PhD

Blood (2019) 134 (Supplement_1): 3727.

https://doi.org/10.1182/blood-2019-124453

Published: 2019

Journal Articles

Metabolic Control and Systems Immunology in Blood Cell Development

Hongbo Chi, PhD

Blood (2019) 134 (Supplement_1): SCI-43.

https://doi.org/10.1182/blood-2019-121089

Published: 2019

Journal Articles

CXCR4 Blockade By BL-8040 in T Cell Acute Lymphoblastic Leukemia Decreases Mitochondrial Mass and Induces Non-Apoptotic Cell Death

Jun Xia, PhD, Stephanie Sun, Matthew RM Jotte, Geoffrey L. Uy, MD, Osnat Bohana-Kashtan, PhD, Ella Sorani, PhD, Abi Vainstein, Amnon Peled, PhD, Daniel C. Link, MD

Blood (2019) 134 (Supplement_1): 2745.

https://doi.org/10.1182/blood-2019-128881

Published: 2019

Journal Articles

Initial Characterization and Toxicology of an Nmt Inhibitor in Development for Hematologic Malignancies

Michael Weickert, John Dillberger, John R. Mackey, Paul Wyatt, David Gray, Kevin Read, Christian Li, Audrey Parenteau, Luc G. Berthiaume

Blood (2019) 134 (Supplement_1): 3362.

https://doi.org/10.1182/blood-2019-124934

Published: 2019

Journal Articles

Carbon Dots As a Potential Therapeutic Agent for Anemia Treatment in Malignancies

Yuanlin Xu, Boyang Wang, Huan Zhang, Xiaoli Qu, Mingming Zhang, Xiuli An, Siyu Lu, Shijie Zhang

Blood (2019) 134 (Supplement_1): 941.

https://doi.org/10.1182/blood-2019-130971

Published: 2019

Journal Articles

S-Adenosyl Methionine Synthesis Impacts Maintenance of Acute Myeloid Leukemia Cells with Regulation of Transcriptional Elongation

Alice V Taylor, BSc PGCE, Rita Romano Adao, MPharm, Cecilia Castro, PhD, Ana Filipa Domingues, MSc, Jules L Griffin, PhD, Antonio Curti, Cristina Pina, MD DPhil

Blood (2018) 132 (Supplement 1): 2605.

https://doi.org/10.1182/blood-2018-99-115004

Published: 2018

Journal Articles

Proteome Analyses and Single-Cell RNA Sequencing Reveal Age-Dependent Re-Wiring of Central Carbon Metabolism in Myeloid-Biased Subsets of Human Hematopoietic Stem Cells

Marco L Hennrich, PhD, Natalie Romanov, Patrick Horn, PhD, Samira Jaeger, PhD, Volker Eckstein, PhD, Laura Poisa-Beiro, PhD, Jacqueline Boultwood, PhD, Thomas Luft, MD PhD, Andrea Pellagatti, PhD, Peer Bork, PhD, Patrick Aloy, PhD, Anne-Claude Gavin, PhD, Anthony D. Ho, MD FRCPC

Blood (2018) 132 (Supplement 1): 873.

https://doi.org/10.1182/blood-2018-99-110787

Published: 2018

Journal Articles

Isoprenoid Amide Bisphosphonates As a Novel Class of Geranylgeranyl Diphosphate Synthase Inhibitors

Michelle L. Varney, MS, Daniel B. Goetz, BA, David F. Wiemer, PhD, Sarah A. Holstein, MD PhD

Blood (2018) 132 (Supplement 1): 4679.

https://doi.org/10.1182/blood-2018-99-112965

Published: 2018

Journal Articles

In Vivo Evaluation of Novel Geranylgeranyl Diphosphate Synthase Inhibitors

Staci L. Haney, PhD, Yashpal S. Chhonker, PhD, Michelle L. Varney, MS, Geoffrey A. Talmon, MD, Daryl J. Murry, PharmD, Sarah A. Holstein, MD PhD

Blood (2018) 132 (Supplement 1): 215.

https://doi.org/10.1182/blood-2018-99-113007

Published: 2018

Journal Articles

Mcl-1/CDK9 Targeting By AZD5991/AZD4573 Overcomes Intrinsic and Acquired Venetoclax Resistance in Vitro and In Vivo in PDX Model of AML through Modulation of Cell Death and Metabolic Functions

Bing Z Carter, PhD, Po Yee Mak, Wenjing Tao, Mark Warmoes, Philip L Lorenzi, PhD, Duncan Mak, BSc, MPhil, Vivian Ruvolo, MS, Xiangmeng Wang, Huaxian Ma, MS, Hong Mu, MD PhD, Justin Cidado, PhD, Lisa Drew, PhD, Michael Andreeff, MD PhD

Blood (2018) 132 (Supplement 1): 768.

https://doi.org/10.1182/blood-2018-99-113491

Published: 2018

Journal Articles

Heme, whence come thy carbon building blocks?

Tracey A. Rouault

Blood (2018) 132 (10): 981–982.

https://doi.org/10.1182/blood-2018-07-864215

Published: 2018

Journal Articles

Understanding the Transferrin Receptor and Cellular Iron Deficiency Outside the Erythron

Nancy C. Andrews, MD PhD

Blood (2017) 130 (Supplement 1): SCI-42.

https://doi.org/10.1182/blood.V130.Suppl_1.SCI-42.SCI-42

Published: 2017

Journal Articles

CBFβ-SMMHC Inhibition Disrupts Enhancer Chromatin Dynamics and Represses MYC Transcriptional Program in Inv(16) Leukemia

John Anto Pulikkan, PhD, Mahesh Hegde, Houda Belaghzal, Anuradha Illendula, Jun Yu, Hafiz Ahmed, Kelsey O'Hagen, Jianhong Ou, Carsten Müller-Tidow, Scot A. Wolfe, Julie Zhu, Job Dekker, John H. Bushweller, Lucio H. Castilla

Blood (2017) 130 (Supplement 1): 784.

https://doi.org/10.1182/blood.V130.Suppl_1.784.784

Published: 2017

Journal Articles

Platelets Feeding Bacteria with Lactate during Room Temperature Storage: Mitigated By Refrigeration

Patrick Ketter, PhD, Bernard Arulanandam, PhD, Andrew P. Cap, MD PhD

Blood (2017) 130 (Supplement 1): 2407.

https://doi.org/10.1182/blood.V130.Suppl_1.2407.2407

Published: 2017

Journal Articles

Glutamine Catabolism Maintains MCL-1 Expression in Glucose-Deprived Multiple Myeloma

Changyong Wei, PhD BS, Richa Bajpai, PhD, Alisha D Hunter, MS, Darius Mahboubi, MS, Mala Shanmugam, PhD

Blood (2017) 130 (Supplement 1): 3076.

https://doi.org/10.1182/blood.V130.Suppl_1.3076.3076

Published: 2017

Journal Articles

Multi-Walled Carbon Nano-Tubes (MWCNTs) Accelerate Leukaemia Development in Mice: Implications for Drug Development in Humans

Bin Yin, PhD, Xiaofeng Han, PhD, Huikai Miao, Min Zhang, Yanwen Zheng, Huiquan Tao, Guangsong Su, Zhengwei Mao, Haiyan Xu, Hongchao Yin, Jiang Hu, Robert Peter Gale, MD ScD, PhD, Fanqing Chen

Blood (2017) 130 (Supplement 1): 5099.

https://doi.org/10.1182/blood.V130.Suppl_1.5099.5099

Published: 2017

NARROW

A prospective, blinded study of a PF4-dependent assay for HIT diagnosis

Targeted Delivery of Nanocarrier-Conjugated Doxorubicin to Widen the Therapeutic Window of the Most Active Drug in Lymphoma Therapeutics

Epigenetic Activation of the pH Regulator MCT4 in Acute Myeloid Leukemia Exploits a Fundamental Metabolic Process of Enhancing Cell Growth through Proton Shifting

The Distinctive Metabolic Environment of the Bone Marrow Niche Drives Leukemia Chemoresistance

Inhibition of Anti-Apoptotic Mcl-1 Exerts Anti-Leukemia Activity through Modulation of Leukemia-Stromal Interactions and Metabolic Functions in AML

Metabolic Control and Systems Immunology in Blood Cell Development

CXCR4 Blockade By BL-8040 in T Cell Acute Lymphoblastic Leukemia Decreases Mitochondrial Mass and Induces Non-Apoptotic Cell Death

Initial Characterization and Toxicology of an Nmt Inhibitor in Development for Hematologic Malignancies

Carbon Dots As a Potential Therapeutic Agent for Anemia Treatment in Malignancies

S-Adenosyl Methionine Synthesis Impacts Maintenance of Acute Myeloid Leukemia Cells with Regulation of Transcriptional Elongation

Proteome Analyses and Single-Cell RNA Sequencing Reveal Age-Dependent Re-Wiring of Central Carbon Metabolism in Myeloid-Biased Subsets of Human Hematopoietic Stem Cells

Isoprenoid Amide Bisphosphonates As a Novel Class of Geranylgeranyl Diphosphate Synthase Inhibitors

In Vivo Evaluation of Novel Geranylgeranyl Diphosphate Synthase Inhibitors

Mcl-1/CDK9 Targeting By AZD5991/AZD4573 Overcomes Intrinsic and Acquired Venetoclax Resistance in Vitro and In Vivo in PDX Model of AML through Modulation of Cell Death and Metabolic Functions

Heme, whence come thy carbon building blocks?

Understanding the Transferrin Receptor and Cellular Iron Deficiency Outside the Erythron

CBFβ-SMMHC Inhibition Disrupts Enhancer Chromatin Dynamics and Represses MYC Transcriptional Program in Inv(16) Leukemia

Platelets Feeding Bacteria with Lactate during Room Temperature Storage: Mitigated By Refrigeration

Glutamine Catabolism Maintains MCL-1 Expression in Glucose-Deprived Multiple Myeloma

Multi-Walled Carbon Nano-Tubes (MWCNTs) Accelerate Leukaemia Development in Mice: Implications for Drug Development in Humans

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American Society of Hematology

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American Society of Hematology

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