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Journal Articles

The metabolic enzyme pyruvate kinase M2 regulates platelet function and arterial thrombosis

Manasa K. Nayak, Madankumar Ghatge, Gagan D. Flora, Nirav Dhanesha, Manish Jain, Kathleen R. Markan, Matthew J. Potthoff, Steven R. Lentz, Anil K. Chauhan

Blood (2021) 137 (12): 1658–1668.

https://doi.org/10.1182/blood.2020007140

Published: 2021

Includes: Supplemental data

Journal Articles

Targeting Myeloid-Cell Specific Integrin α9β1 Inhibits Arterial Thrombosis in Mice

Nirav Dhanesha, PhD, Manasa K Nayak, PhD, Prakash Doddapattar, PhD, Anil K Chauhan, PhD

Blood (2019) 134 (Supplement_1): 3581.

https://doi.org/10.1182/blood-2019-127006

Published: 2019

Journal Articles

Targeting Metabolic Enzyme Pyruvate Kinase M2: A Novel Strategy to Inhibit Platelet Function and Arterial Thrombosis

Manasa K Nayak, PhD, Madankumar Ghatge, PhD, Nirav Dhanesha, PhD, Gagan D Flora, PhD, Manish Jain, PhD, Omar Rodriguez, MD BS, Kathleen Markan, PhD, Mathhhew Potthoff, PhD, Steven R. Lentz, MD PhD, Anil K Chauhan, PhD

Blood (2019) 134 (Supplement_1): 1056.

https://doi.org/10.1182/blood-2019-129027

Published: 2019

Journal Articles

M6PR-Specific Targeting of Lysosomal Heparanase Regulates Platelet Hemostatic Function in Mice

Nathan Eaton, BS, Caleb Drew, BS, Theresa A. Dlugi, PhD, Karin M. Hoffmeister, MD, Hervé Falet, PhD

Blood (2019) 134 (Supplement_1): 1059.

https://doi.org/10.1182/blood-2019-129075

Published: 2019

Journal Articles

RhoA Targeting Suppresses Cold-Induced Platelet Lesion and Allows Refrigerated Storage of Functional Human Platelets to Fourteen Days

Shailaja N Hegde, PhD, Huzoor Akbar, PhD, Shawnagay Nestheide, BS, Ashley M Wellendorf, B.S., Breanna Bohan, James F Johnson, Yi Zheng, PhD, Jose A Cancelas, MD

Blood (2019) 134 (Supplement_1): 99.

https://doi.org/10.1182/blood-2019-125359

Published: 2019

Journal Articles

The Safety of Novel Drugs Targeting Factor XI and XII in Human Clinical Trials:a Systematic Review

Gillian E Mair, Sven Reid Olson, MD, Joseph J Shatzel, MD

Blood (2019) 134 (Supplement_1): 4966.

https://doi.org/10.1182/blood-2019-130823

Published: 2019

Journal Articles

Synthetic Platelets for Treatment of Traumatic Hemorrhage and Thrombocytopenia

Anirban Sen Gupta, PhD

Blood (2019) 134 (Supplement_1): SCI-37.

https://doi.org/10.1182/blood-2019-121079

Published: 2019

Journal Articles

Nanoparticles Mimicking Platelets and Platelet Cloaking

Liangfang Zhang, PhD

Blood (2019) 134 (Supplement_1): SCI-38.

https://doi.org/10.1182/blood-2019-121082

Published: 2019

Journal Articles

Blockade of Lipid Receptor GPR31 Suppresses Platelet Reactivity and Thrombosis with Minimal Effect on Hemostasis

Layla Van Doren, MD, Nga Nguyen, BSc, Chris Garzia, BSc, Elizabeth Fletcher, PhD, Ryan Stevenson, MD, David Jaramillo, MSc, Athan Kuliopulos, MD PhD, Lidija Covic, PhD

Blood (2019) 134 (Supplement_1): 1064.

https://doi.org/10.1182/blood-2019-126111

Published: 2019

Journal Articles

Evaluation of Efficacy and Safety of Cold-Stored Platelets in Healthy Human Subjects Treated with Dual Antiplatelet Therapy

Jeffrey Miles, M.S., Shawn Lawrence Bailey, BS, Lydia Fang, M.S., Barbara Osborne, RN, Jill Corson, RN, Johnathan P. Mack, MD, Moritz Stolla, MD

Blood (2019) 134 (Supplement_1): 718.

https://doi.org/10.1182/blood-2019-124122

Published: 2019

Journal Articles

Tannic Acid Inhibits Protein Disulfide Isomerase, Platelet Activation and Thrombus Formation

Li Zhu, MD PhD

Blood (2018) 132 (Supplement 1): 2418.

https://doi.org/10.1182/blood-2018-99-114418

Published: 2018

Journal Articles

Mitochondrial Uncoupling Prevents Procoagulant Platelet Formation Resulting in Decreased Thrombus Stability

Andaleb Kholmukhamedov, MD, Yumiko Sakurai, MSc, Elaissa L. Hardy, PhD, Wilbur A Lam, MD PhD, Shawn M. Jobe, MD PhD

Blood (2018) 132 (Supplement 1): 2421.

https://doi.org/10.1182/blood-2018-99-117004

Published: 2018

Journal Articles

Short-Acting Anti-VWF Aptamer Improves the Recovery and Survival, and Hemostatic Functions of Refrigerated Platelets

Wenchun Chen, PhD, Kayleigh M Voos, BS, Cassandra D Josephson, MD, Renhao Li, PhD

Blood (2018) 132 (Supplement 1): 741.

https://doi.org/10.1182/blood-2018-99-113955

Published: 2018

Journal Articles

A Murine Model of Type 2N VWD Was Developed By CRISPR/Cas9 Gene Editing and Recapitulates Human Type 2N VWD

Robert R Montgomery, MD, Scot A Fahs, Jeremy G Mattson, Hartmut Weiler, PhD, Qizhen Shi, MD

Blood (2018) 132 (Supplement 1): 221.

https://doi.org/10.1182/blood-2018-99-110324

Published: 2018

Journal Articles

Hepatocyte-Derived Tissue Plasminogen Activator Regulates Systemic Fibrinolysis

Ze Zheng, MDPhD, Lalitha V. Nayak, MD, Mukesh Jain, Ira Tabas, MD PhD

Blood (2018) 132 (Supplement 1): 217.

https://doi.org/10.1182/blood-2018-99-119362

Published: 2018

Journal Articles

Platelet-Targeted Hyperfunctional Factor IX (FIX) Gene Therapy for Hemophilia B Mice with Pre-Existing Anti-FIX Immunity

Jocelyn A. Schroeder, Jeremy G Mattson, Paul Edward Monahan, MD, Qizhen Shi, MD

Blood (2018) 132 (Supplement 1): 220.

https://doi.org/10.1182/blood-2018-99-111718

Published: 2018

Journal Articles

Intrinsic apoptosis circumvents the functional decline of circulating platelets but does not cause the storage lesion

Irina Pleines, Marion Lebois, Pradnya Gangatirkar, Amanda E. Au, Rachael M. Lane, Katya J. Henley, Maria Kauppi, Jason Corbin, Ping Cannon, Jonathan Bernardini, Imala Alwis, Kate E. Jarman, Sarah Ellis, Donald Metcalf, Shaun P. Jackson, Simone M. Schoenwaelder, Benjamin T. Kile, Emma C. Josefsson

Blood (2018) 132 (2): 197–209.

https://doi.org/10.1182/blood-2017-11-816355

Published: 2018

Includes: Supplemental data

Journal Articles

Myosin IIa is critical for cAMP-mediated endothelial secretion of von Willebrand factor

Pin Li, Guoqin Wei, Yang Cao, Qiuping Deng, Xiaofan Han, Xiaoshuai Huang, Yingqing Huo, Yulong He, Liangyi Chen, Jincai Luo

Blood (2018) 131 (6): 686–698.

https://doi.org/10.1182/blood-2017-08-802140

Published: 2018

Includes: Multimedia, Supplemental data

Journal Articles

CK2β regulates thrombopoiesis and Ca 2+ -triggered platelet activation in arterial thrombosis

Blood (2017) 130 (25): 2774–2785.

https://doi.org/10.1182/blood-2017-05-784413

Published: 2017

Includes: Multimedia, Supplemental data

Journal Articles

The Anti-Factor XII Antibody AB052 Is Antithrombotic without Hemostatic Impairment in a Primate Model of Extracorporeal Membrane Oxygenation

Michael Wallisch, PhD, Erik I Tucker, PhD, Christina U Lorentz, PhD, Jennifer Johnson, RLATG, Marschelle R Carris, BA, Owen JT McCarty, PhD, Monica T Hinds, PhD, András Gruber, MD

Blood (2017) 130 (Supplement 1): 236.

https://doi.org/10.1182/blood.V130.Suppl_1.236.236

Published: 2017

NARROW

The metabolic enzyme pyruvate kinase M2 regulates platelet function and arterial thrombosis

Targeting Myeloid-Cell Specific Integrin α9β1 Inhibits Arterial Thrombosis in Mice

Targeting Metabolic Enzyme Pyruvate Kinase M2: A Novel Strategy to Inhibit Platelet Function and Arterial Thrombosis

M6PR-Specific Targeting of Lysosomal Heparanase Regulates Platelet Hemostatic Function in Mice

RhoA Targeting Suppresses Cold-Induced Platelet Lesion and Allows Refrigerated Storage of Functional Human Platelets to Fourteen Days

The Safety of Novel Drugs Targeting Factor XI and XII in Human Clinical Trials:a Systematic Review

Synthetic Platelets for Treatment of Traumatic Hemorrhage and Thrombocytopenia

Nanoparticles Mimicking Platelets and Platelet Cloaking

Blockade of Lipid Receptor GPR31 Suppresses Platelet Reactivity and Thrombosis with Minimal Effect on Hemostasis

Evaluation of Efficacy and Safety of Cold-Stored Platelets in Healthy Human Subjects Treated with Dual Antiplatelet Therapy

Tannic Acid Inhibits Protein Disulfide Isomerase, Platelet Activation and Thrombus Formation

Mitochondrial Uncoupling Prevents Procoagulant Platelet Formation Resulting in Decreased Thrombus Stability

Short-Acting Anti-VWF Aptamer Improves the Recovery and Survival, and Hemostatic Functions of Refrigerated Platelets

A Murine Model of Type 2N VWD Was Developed By CRISPR/Cas9 Gene Editing and Recapitulates Human Type 2N VWD

Hepatocyte-Derived Tissue Plasminogen Activator Regulates Systemic Fibrinolysis

Platelet-Targeted Hyperfunctional Factor IX (FIX) Gene Therapy for Hemophilia B Mice with Pre-Existing Anti-FIX Immunity

Intrinsic apoptosis circumvents the functional decline of circulating platelets but does not cause the storage lesion

Myosin IIa is critical for cAMP-mediated endothelial secretion of von Willebrand factor

CK2β regulates thrombopoiesis and Ca 2+ -triggered platelet activation in arterial thrombosis

The Anti-Factor XII Antibody AB052 Is Antithrombotic without Hemostatic Impairment in a Primate Model of Extracorporeal Membrane Oxygenation

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American Society of Hematology

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American Society of Hematology

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