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Journal Articles

Development of CD38 CAR Engineered Human Placental Hematopoietic Stem Cell Derived Natural Killer Cells (PNK-CAR38) As Allogeneic Cancer Immunotherapy

Srinivas Somanchi, PhD, Xuan Guo, PhD, Shuyang He, PhD, Rohit Mathur, PhD, Andrea Difiglia, BS, Hemlata Rana, MS, Weifang Ling, PhD, James Edinger, PhD, Gunnar F. Kaufmann, PhD, Jerome B. Zeldis, MD PhD, Henry Ji, PhD, Robert Hariri, MD PhD, Xiaokui Zhang, PhD

Blood (2019) 134 (Supplement_1): 2070.

https://doi.org/10.1182/blood-2019-129539

Published: 2019

Journal Articles

Effective Novel Fto Inhibitors Show Potent Anti-Cancer Efficacy and Suppress Drug Resistance

Blood (2019) 134 (Supplement_1): 233.

https://doi.org/10.1182/blood-2019-124535

Published: 2019

Journal Articles

B-Cell Maturation Antigen (BCMA) in Systemic Light-Chain Amyloidosis (AL): Association with Disease Activity and Its Modulation with Gamma-Secretase Inhibition

Amandeep Godara, MD, Ping Zhou, MD PhD, Benjamin Rosenthal, BS, Adin Kugelmass, BSc, Denis Toskic, BS, Teresa Fogaren, NP, Cindy Varga, MD BSc, Raymond L Comenzo, MD

Blood (2019) 134 (Supplement_1): 4409.

https://doi.org/10.1182/blood-2019-126988

Published: 2019

Journal Articles

Mitochondrial Oxphos As Survival Mechanism of Minimal Residual AML Cells after Induction Chemotherapy : Survival Benefit By Complex I Inhibition with Iacs-010759

Lina Han, PhD, Antonio Cavazos, Natalia Baran, PhDMD, Qi Zhang, PhD, Vinitha Mary Kuruvilla, MSc, Jason P Gay, MS, Ningping Feng, PhD, Venkata Lokesh Battula, PhD, Hagop M. Kantarjian, MD, Naval G. Daver, MD, Joseph R Marszalek, PhD, Michael Andreeff, MD PhD, Marina Y Konopleva, MD PhD

Blood (2019) 134 (Supplement_1): 5161.

https://doi.org/10.1182/blood-2019-124475

Published: 2019

Journal Articles

T Cells Educated By DC/AML Fusions in the Context of 4-1BB Costimulation As a Potent Strategy for Adoptive Cellular Therapy

Jessica Liegel, MD, Dina Stroopinsky, PhD, Haider Ghiasuddin, Adam Morin, Marzia Capelletti, PhD MMSc, Shira Orr, PhD, Maryam Rahimian, MD, Lina Bisharat, Shufen Meng, MD, Myrna Nahas, MD, Matthew Weinstock, MD, Donald Kufe, MD, Jacalyn Rosenblatt, MD, David E. Avigan, MD

Blood (2019) 134 (Supplement_1): 2673.

https://doi.org/10.1182/blood-2019-131491

Published: 2019

Journal Articles

Dual-Switch CAR-T Cells: Orthogonal Molecular Switches to Control Activation and Elimination of CAR-T Cells to Target CD123 + Cancer

J. Henri Bayle, PhD, MyLinh T Duong, PhD, An Lu, Eva Morschl, PhD, Matthew R. Collinson-Pautz, PhD, Kelly L Sharp, Slawomir Szymanski, PhD, Mary E. Brandt, Kevin M. Slawin, MD, Steven Toler, PhD, Eric Yvon, S., Aaron Foster, David M. Spencer

Blood (2017) 130 (Supplement 1): 3184.

https://doi.org/10.1182/blood.V130.Suppl_1.3184.3184

Published: 2017

Journal Articles

Second-Generation Camelid Trike Induces Improved NK Cell Mediated Targeting of AML in Pre-Clinical Models

Martin Felices, PhD, Craig E. Eckfeldt, MD PhD, Todd R Lenvik, Behiye Kodal, Alexander J. Lenvik, Laura Bendzick, Caitlin Ryan, Melissa A. Geller, Sarah Cooley, MD, Daniel J. Weisdorf, MD, Daniel A. Vallera, PhD, Jeffrey S. Miller, MD

Blood (2017) 130 (Supplement 1): 4465.

https://doi.org/10.1182/blood.V130.Suppl_1.4465.4465

Published: 2017

Journal Articles

Xpo-1 Inhibition Synergizes with BCR Inhibition, Blocks Tumor Growth and Tumor-Associated Macrophages Infiltration and Prolongs Survival in a Bioluminescent Animal Model of Primary Central Nervous System Lymphoma

Marta Crespo, PhD, Júlia Carabia, MSc, Isabel Jiménez, MSc, Sabela Bobillo, MD, Pau Abrisqueta, MD PhD, Carles Palacio, MD, Juan C Nieto, PhD, Joan Boix, BSc, Cecilia Carpio, MD, Josep Castellvi, Joan Seoane, Francesc Bosch

Blood (2017) 130 (Supplement 1): 2808.

https://doi.org/10.1182/blood.V130.Suppl_1.2808.2808

Published: 2017

Journal Articles

Clones with and without Sensitivity Towards Treatment In Vivo Co-Exist within the Tumor Cells of a Single Patient with ALL

Cornelia Finkenzeller, MSc, Michela Carlet, PhD, Sebastian Vosberg, Christoph Ziegenhain, MSc, Martin Neumann, MD, Kristoffer Riecken, PhD, Kerstin Cornils, PhD, Boris Fehse, PhD, Claudia D. Baldus, MD, Wolfgang Enard, Prof. Dr. rer. nat., Philipp A. Greif, MD, Irmela Jeremias, MD

Blood (2016) 128 (22): 456.

https://doi.org/10.1182/blood.V128.22.456.456

Published: 2016

Journal Articles

XPO1 Inhibition By Selinexor Synergizes with BCR Inhibition, Blocks Tumor Growth and Prolongs Survival in a Bioluminescent Animal Model of Primary Central Nervous System Lymphoma

Marta Crespo, Julia Carabia, Isabel Jiménez, Sabela Bobillo, Pau Abrisqueta, Carles Palacio, Cecilia Carpio, MD, Josep Castellvi, Noelia Purroy, Joan Seoane, Francesc Bosch, MD PhD

Blood (2016) 128 (22): 463.

https://doi.org/10.1182/blood.V128.22.463.463

Published: 2016

Journal Articles

Erythromer (EM), a Nanoscale Bio-Synthetic Artificial Red Cell: Proof of Concept and I n Vivo Efficacy Results

Dipanjan Pan, PhD, Stephen Rogers, PhD, Santosh Misra, PhD, Gururaja Vulugundam, PhD, Lisa Gazdzinski, MS, Albert Tsui, PhD, Nikhil Mistry, MS, Ahmed Said, MD PhD, Philip Spinella, MD, Greg Hare, MD PhD, Greg Lanza, MD PhD, Allan Doctor, MD

Blood (2016) 128 (22): 1027.

https://doi.org/10.1182/blood.V128.22.1027.1027

Published: 2016

Journal Articles

DR3 Signaling Modulates the Function of Foxp3 + regulatory T Cells and the Severity of Acute Graft and Host Disease

Hidekazu Nishikii, MD PhD, Kim Byung-Su, Yan Chen, MD, Jeanette Baker, PhD, Antonio Pierini, MD, Maite Alvarez, PhD, Melissa Mavers, MD, Kristina Maas-Bauer, MD, Robert S. Negrin, MD

Blood (2016) 128 (22): 2148.

https://doi.org/10.1182/blood.V128.22.2148.2148

Published: 2016

Journal Articles

A Novel Bioluminescent Mouse Model for Optimization of Adoptive T Cell Therapy

Martin Szyska, PhD, Stefanie Herda, PhD, Stefanie Althoff, Andreas Heimann, Tra My Dang, Bernd Dörken, MD PhD, Thomas Blankenstein, Il-Kang Na, MD

Blood (2016) 128 (22): 2162.

https://doi.org/10.1182/blood.V128.22.2162.2162

Published: 2016

Journal Articles

Osteocyte Apoptosis Attracts Myeloma Cells to Bone and Supports Progression through Regulation of the Bone Marrow Microenvironment

Timothy N. Trotter, Mary Fok, Justin T. Gibson, Deniz Peker, MD, Amjad Javed, MSc, PhD, Yang Yang, MD PhD

Blood (2016) 128 (22): 484.

https://doi.org/10.1182/blood.V128.22.484.484

Published: 2016

Journal Articles

Silencing TG2 in Acute Myeloid Leukemia. Possible Role of TG2 in Microenvironment-Mediated Chemoresistance

Rodrigo Omar Jacamo, PhD, Qi Zhang, MD PhD, Teresa McQueen, MS, Richard Eric Davis, MD, Marina Konopleva, MD PhD, Michael Andreeff, MD PhD

Blood (2016) 128 (22): 5087.

https://doi.org/10.1182/blood.V128.22.5087.5087

Published: 2016

Journal Articles

Identification of CCND2 As a RUNX1/ETO Target Required for Leukaemic Propagation

Lynsey McKenzie, PhD, Natalia Martinez-Soria, PhD, Julia Draper, DPhil, Sirintra Nakjang, PhD, Helen J Blair, PhD, Christian Wichmann, MD, Josef Vormoor, MD FRCPCH, Constanze Bonifer, PhD, Georges Lacaud, PhD, Olaf Heidenreich, PhD

Blood (2016) 128 (22): 835.

https://doi.org/10.1182/blood.V128.22.835.835

Published: 2016

Journal Articles

Bioluminescent reporters to monitor killer cell–mediated delivery of granzymes inside target cells

Stefanie A. H. de Poot, Elisabeth A. van Erp, Jan Meeldijk, Roel Broekhuizen, Roel Goldschmeding, Marjolein C. Olthof, Elisabeth M. P. Steeghs, Niels Bovenschen

Blood (2015) 126 (26): 2893–2895.

https://doi.org/10.1182/blood-2015-07-657841

Published: 2015

Includes: Supplemental data

Journal Articles

Lateral Gene Transfer Contributing to Leukemogenesis

Joo Hyun Lee, BS, Cynthia R. Giver, PhD, Sravanti Rangaraju, MD MBBS, Edmund K Waller, MD PhD

Blood (2015) 126 (23): 1235.

https://doi.org/10.1182/blood.V126.23.1235.1235

Published: 2015

Journal Articles

Novel Nanomolar Potency Mitochondrial Complex I Inhibitor Iacs-1131 Selectively Kills Oxphos-Dependent AML Cells

Polina Matre, PhD, Marina Protopopova, Ningping Feng, Jason Gay, Jennifer Greer, Juliana Velez, Hong Mu, MD PhD, Alessia Lodi, Surendar Tadi, Shannon Sweeney, Michael Andreeff, MD PhD, Stefano Tiziani, M. Emilia DiFrancesco, Joseph Marszalek, Marina Konopleva, MD PhD

Blood (2014) 124 (21): 622.

https://doi.org/10.1182/blood.V124.21.622.622

Published: 2014

Journal Articles

CD123-Engager T Cells As a Novel Immunotherapeutic for AML

Challice L. Bonifant, MD PhD, David Torres, Mireya Paulina Velasquez, MD, Kota Iwahori, MD, Caroline Arber, MD, Xiao-Tong Song, PhD, Michele S. Redell, MD PhD, Stephen Gottschalk, MD

Blood (2014) 124 (21): 3762.

https://doi.org/10.1182/blood.V124.21.3762.3762

Published: 2014

NARROW

Development of CD38 CAR Engineered Human Placental Hematopoietic Stem Cell Derived Natural Killer Cells (PNK-CAR38) As Allogeneic Cancer Immunotherapy

Effective Novel Fto Inhibitors Show Potent Anti-Cancer Efficacy and Suppress Drug Resistance

B-Cell Maturation Antigen (BCMA) in Systemic Light-Chain Amyloidosis (AL): Association with Disease Activity and Its Modulation with Gamma-Secretase Inhibition

Mitochondrial Oxphos As Survival Mechanism of Minimal Residual AML Cells after Induction Chemotherapy : Survival Benefit By Complex I Inhibition with Iacs-010759

T Cells Educated By DC/AML Fusions in the Context of 4-1BB Costimulation As a Potent Strategy for Adoptive Cellular Therapy

Dual-Switch CAR-T Cells: Orthogonal Molecular Switches to Control Activation and Elimination of CAR-T Cells to Target CD123 + Cancer

Second-Generation Camelid Trike Induces Improved NK Cell Mediated Targeting of AML in Pre-Clinical Models

Xpo-1 Inhibition Synergizes with BCR Inhibition, Blocks Tumor Growth and Tumor-Associated Macrophages Infiltration and Prolongs Survival in a Bioluminescent Animal Model of Primary Central Nervous System Lymphoma

Clones with and without Sensitivity Towards Treatment In Vivo Co-Exist within the Tumor Cells of a Single Patient with ALL

XPO1 Inhibition By Selinexor Synergizes with BCR Inhibition, Blocks Tumor Growth and Prolongs Survival in a Bioluminescent Animal Model of Primary Central Nervous System Lymphoma

Erythromer (EM), a Nanoscale Bio-Synthetic Artificial Red Cell: Proof of Concept and I n Vivo Efficacy Results

DR3 Signaling Modulates the Function of Foxp3 + regulatory T Cells and the Severity of Acute Graft and Host Disease

A Novel Bioluminescent Mouse Model for Optimization of Adoptive T Cell Therapy

Osteocyte Apoptosis Attracts Myeloma Cells to Bone and Supports Progression through Regulation of the Bone Marrow Microenvironment

Silencing TG2 in Acute Myeloid Leukemia. Possible Role of TG2 in Microenvironment-Mediated Chemoresistance

Identification of CCND2 As a RUNX1/ETO Target Required for Leukaemic Propagation

Bioluminescent reporters to monitor killer cell–mediated delivery of granzymes inside target cells

Lateral Gene Transfer Contributing to Leukemogenesis

Novel Nanomolar Potency Mitochondrial Complex I Inhibitor Iacs-1131 Selectively Kills Oxphos-Dependent AML Cells

CD123-Engager T Cells As a Novel Immunotherapeutic for AML

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American Society of Hematology

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ASH Publications

American Society of Hematology

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