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Journal Articles

Myeloma Derived Extracellular Vesicles Containing Endoplasmic Reticulum Remodel the Bone Marrow Microenvironment Towards a Pro-Tumoral Senescent Phenotype

Yu Sun, BSc, MSc, PhD, Jayna J Mistry, BSc, Jamie A Moore, BSc, MSc, Charlotte Hellmich, MBBChir, Christopher R Marlein, PhD, Anna Haestier, Cesar A. Gomez, MD PhD FRCPath, Christopher J Morris, PhD, Kristian M Bowles, MBBS, PhD, Stuart A Rushworth, PhD

Blood (2019) 134 (Supplement_1): 689.

https://doi.org/10.1182/blood-2019-128268

Published: 2019

Journal Articles

The mTOR Component, Rictor, Is Regulated By the Microenvironment to Control Dormancy and Proliferative States in Myeloma Cells

Syed J. Mehdi, PhD, Sarah K Johnson, PhD, Tarun K. Garg, PhD, Cody Ashby, PhD, Maurizio Zangari, MD, Carolina D. Schinke, MD, Sharmilan Thanendrarajan, MD, Joshua Epstein, DSc, Brian A Walker, PhD, Frits van Rhee, MD PhD, Shmuel Yaccoby, PhD

Blood (2019) 134 (Supplement_1): 4412.

https://doi.org/10.1182/blood-2019-127382

Published: 2019

Journal Articles

Multiple Myeloma Staging in Real World Clinical Practice Is Suboptimal: Absence of Beta-2-Microglobulin and Serum Lactase Dehydrogenase Testing Are Limiting Factors

Noa Biran, MD, Sukhmani Gill, MD, Andrew D Norden, MD MPH MBA, David H. Vesole, MD PhD, Wallace G Stephen, MD, Kenneth D Nahum, DO, David S Siegel, MD PhD, Stuart L. Goldberg, MD

Blood (2018) 132 (Supplement 1): 5587.

https://doi.org/10.1182/blood-2018-99-119559

Published: 2018

Journal Articles

HB9 Represses Hematopoietic Stem Cell Proliferation and Induces Senescence

Deborah Ingenhag, MSc, Franziska Auer, MSc, Arndt Borkhardt, MD, Julia Hauer, MD

Blood (2016) 128 (22): 1539.

https://doi.org/10.1182/blood.V128.22.1539.1539

Published: 2016

Journal Articles

Predicting Early Mortality in Diffuse Large B-Cell Non-Hodgkin Lymphoma

Jamie M Maddox, MBChB, MRCP, FRCPath

Blood (2016) 128 (22): 5411.

https://doi.org/10.1182/blood.V128.22.5411.5411

Published: 2016

Journal Articles

Prognostic Comparison Between ISS and R-ISS in Real-Life Setting of Myeloma Patients: An Example of Utilization of Electronic Biobank Database

Samu Kurki, PhD, Klaus Tamminen, MD, Tatu Miettinen, MD, Kari Remes, MD PhD

Blood (2016) 128 (22): 5645.

https://doi.org/10.1182/blood.V128.22.5645.5645

Published: 2016

Journal Articles

Humanized Anti-PR1/HLA-A2 T Cell Receptor-like Monoclonal Antibody, h8F4, Has Multiple Effector Mechanisms

Anna Sergeeva, PhD, Hong He, MD, Kathryn Cox, Lisa St John, PhD, Mei Sang, Celine Kerros, PhD, Qiaochuan Li, PhD MD, Amanda Herrmann, Karen Clise-Dwyer, PhD, Qing Ma, PhD, Gregory Lizee, PhD, Gheath Alatrash, DO, PhD, Jeffrey J. Molldrem, MD

Blood (2016) 128 (22): 4061.

https://doi.org/10.1182/blood.V128.22.4061.4061

Published: 2016

Journal Articles

Impaired Lysophosphatidic Acid Receptor 3 Signaling in Mesenchymal Stromal Cells Promotes Multiple Myeloma Progression through Cellular Senescence and Transdifferentiation into Tumor-Associated Fibroblasts

Masahiko Kanehira, DVM, PhD, Tohru Fujiwara, MD PhD, Shinji Nakajima, MD PhD, Yoko Okitsu, MD PhD, Yasushi Ohnishi, MD PhD, Noriko Fukuhara, MD PhD, Ryo Ichinohasama, MD PhD, Hideo Harigae, MD PhD

Blood (2015) 126 (23): 1764.

https://doi.org/10.1182/blood.V126.23.1764.1764

Published: 2015

Journal Articles

Clinical Utility of Slam Family Member CD229 in Identifying Tumor Cells and High-Risk Disease Markers, CD86 (B7-2) and CD126 (IL-6 receptor), Using Flow Cytometric Analysis in Multiple Myeloma

Akiko Yamada, MD, Hideto Tamura, MD PhD, Mariko Ishibashi, PhD, Koiti Inokuchi, MD PhD, Makoto Sasaki, MD PhD, Yuriko Yahata, MD, Norio Komatsu, MD PhD, Atsushi Isoda, MD PhD, Morio Matsumoto, Hiroshi Handa, MD PhD, Yoichi Imai, MD PhD, Junji Tanaka, MD PhD, Sakae Tanosaki, MD PhD, Shigeki Ito, MD, PhD, Yoji Ishida, MD, PhD, Michiaki Koike, MD PhD

Blood (2014) 124 (21): 2063.

https://doi.org/10.1182/blood.V124.21.2063.2063

Published: 2014

Journal Articles

Reverse Phase Protein Analysis of Mesenchymal Stem Cells from AML Patients and Healthy Donors Reveals Distinct Patterns of Protein Expression Reflecting Differences in Senescence, Differentiation and Survival Signaling

Peter P. Ruvolo, PhD, Venkata Lokesh Battula, PhD, YiHua Qui, MD, Vivian R Ruvolo, MA, Rodrigo Jacamo, PhD, Zhihong Zeng, MD, Rui-Yu Wang, MD PhD, Teresa McQueen, BS, Arvind Rao, SukYoung Yoo, Phuong M Le, Numsen Hail, PhD, Bing Z Carter, PhD, Steven M. Kornblau, MD, Michael Andreeff, MD PhD

Blood (2014) 124 (21): 4376.

https://doi.org/10.1182/blood.V124.21.4376.4376

Published: 2014

Journal Articles

Interferon-Inducible Protein 16 (IFI-16) Is Upregulated In Chronic Myeloid Leukemia (CML) and Is Involved In Oncogene-Induced Senescence

Clémentine Bouneau, Marie Laure Bonnet, Marie Claude Meunier, Djamel Aggoune, Fatima Dkhissi, PhD, François Guilhot, MD, Annelise Bennaceur-Griscelli, MD, PhD, Jean-Claude Chomel, PharmD, PhD, Ali G Turhan, MD, PhD

Blood (2013) 122 (21): 2708.

https://doi.org/10.1182/blood.V122.21.2708.2708

Published: 2013

Journal Articles

Glycosylation-Related Gene Expression Is Dysregulated in Multiple Myeloma and Overexpression of the Sialyltransferase ST3GAL6 Is Associated with Inferior Survival.

Siobhan V Glavey, M.B., BCh, BAO, BSc, Stephen Cunningham, PhD, Laura S Murillo, PhD, Catherine Loughrey, MSc, Ping Wu, MBBS, MSc, Michael Cairns, PhD, Satbir Kaur Gill, MSc, Anja Kruger, MSc, Jared Q Gerlach, PhD, Marian Kane, PhD, Gareth J. Morgan, MD PhD, Lokesh Joshi, PhD, Michael E O'Dwyer, MD, FRCPI, FRCPath

Blood (2012) 120 (21): 2931.

https://doi.org/10.1182/blood.V120.21.2931.2931

Published: 2012

Journal Articles

Glycine Supplementation – A Novel Therapeutic Strategy for Congenital Sideroblastic Anemia.

Jason N Berman, MD, Pedro Fernandez-Murray, PhD, Gheyath Nasrallah, PhD, Noelia Dufay, PhD, Conrad V Fernandez, FRCPC, BSc, MD, Ameer Jarrar, MSc, Andrew J Coombs, BSc(Hon), Christopher McMaster, PhD

Blood (2012) 120 (21): 2087.

https://doi.org/10.1182/blood.V120.21.2087.2087

Published: 2012

Journal Articles

In Vitro Propagation of Mesenchymal Stromal Cells From Marrow Aspirates of Patients with Chronic Lymphocytic Leukemia Is Dependent Upon Physiologic Oxygen Tension

Jessie-Farah Fecteau, Ph.D., Davorka Messmer, PhD, Suping Zhang, PhD, Bing Cui, PhD, Liguang Chen, MD, PhD, Thomas J. Kipps, M.D., Ph.D

Blood (2011) 118 (21): 2839.

https://doi.org/10.1182/blood.V118.21.2839.2839

Published: 2011

Journal Articles

Prognostic Value of C-Reactive Protein, Lactase Dehydrogenase and Anemia in Recurrent or Refractory Malignant Lymphoma,

Kazuhito Suzuki, MD, Yasuhito Terui, MD, PhD, Yuko Mishima, MD, Eriko Nara, MD, Kenji Nakano, MD, Kyoko Ueda, MD, Noriko Nishimura, MD, Sakura Sakajiri, MD, Masahiro Yokoyama, MD, Shunji Takahashi, MD, Kiyohiko Hatake

Blood (2011) 118 (21): 3659.

https://doi.org/10.1182/blood.V118.21.3659.3659

Published: 2011

Journal Articles

Tropomodulin3-Null Mice Are Embryonic Lethal with Anemia and Impaired Definitive Erythropoiesis in the Fetal Liver

Roberta B. Nowak, B.S., Andrea Bacconi, Ph.D., Zhenhua Sui, Ph.D., Nancy E. Kim, B.S., Velia M. Fowler, PhD

Blood (2011) 118 (21): 1036.

https://doi.org/10.1182/blood.V118.21.1036.1036

Published: 2011

Journal Articles

Mastl Kinase Gene Disruption Causes Embryonic Lethality.

Helen Jan Johnson, Ph.D., Pavel D Davizon, MD, Jose A. Lopez, MD, Diana M. Gilligan, MD, PhD

Blood (2010) 116 (21): 1567.

https://doi.org/10.1182/blood.V116.21.1567.1567

Published: 2010

Journal Articles

Tracking Senescence In Human Bone Marrow Stromal Cell (BMSC) Cultures.

Jiaqiang Ren, MD, PhD, David Stroncek, MD, Ping Jin, PhD, Luciano Castiello, PhD, Katherine Tran, Sergei Kuznetsov, PhD, Arun Balakumaran, MD, Harvey G Klein, MD, Pamela Robey, PhD, Marianna Sabatino, MD

Blood (2010) 116 (21): 1179.

https://doi.org/10.1182/blood.V116.21.1179.1179

Published: 2010

Journal Articles

Leukemia-Induced Alterations of Bone Marrow Microenvironment Contribute to Leukemogenesis.

Jae-Seung Shim, Myungshin Kim, Jong Wook Lee, MD, PhD, Il-Hoan Oh, MD, PhD

Blood (2010) 116 (21): 2597.

https://doi.org/10.1182/blood.V116.21.2597.2597

Published: 2010

Journal Articles

A New Molecular and Clinical Prognostic Score for Risk Stratification in CN-AML.

Friederike Schneider, Annika Dufour, Tobias Benthaus, Stephanie Schneider, Gudrun Mellert, Evelyn Zellmeier, Stefan K Bohlander, Michael Unterhalt, Michaela Feuring-Buske, Christian Buske, Jan Braess, Maria Cristina Sauerland, Achim Heinecke, Wolfgang Berdel, Thomas Buechner, Bernhard Wörmann, Wolfgang Hiddemann, Karsten Spiekermann, Eva Hoster

Blood (2009) 114 (22): 2635.

https://doi.org/10.1182/blood.V114.22.2635.2635

Published: 2009

NARROW

Myeloma Derived Extracellular Vesicles Containing Endoplasmic Reticulum Remodel the Bone Marrow Microenvironment Towards a Pro-Tumoral Senescent Phenotype

The mTOR Component, Rictor, Is Regulated By the Microenvironment to Control Dormancy and Proliferative States in Myeloma Cells

Multiple Myeloma Staging in Real World Clinical Practice Is Suboptimal: Absence of Beta-2-Microglobulin and Serum Lactase Dehydrogenase Testing Are Limiting Factors

HB9 Represses Hematopoietic Stem Cell Proliferation and Induces Senescence

Predicting Early Mortality in Diffuse Large B-Cell Non-Hodgkin Lymphoma

Prognostic Comparison Between ISS and R-ISS in Real-Life Setting of Myeloma Patients: An Example of Utilization of Electronic Biobank Database

Humanized Anti-PR1/HLA-A2 T Cell Receptor-like Monoclonal Antibody, h8F4, Has Multiple Effector Mechanisms

Impaired Lysophosphatidic Acid Receptor 3 Signaling in Mesenchymal Stromal Cells Promotes Multiple Myeloma Progression through Cellular Senescence and Transdifferentiation into Tumor-Associated Fibroblasts

Clinical Utility of Slam Family Member CD229 in Identifying Tumor Cells and High-Risk Disease Markers, CD86 (B7-2) and CD126 (IL-6 receptor), Using Flow Cytometric Analysis in Multiple Myeloma

Reverse Phase Protein Analysis of Mesenchymal Stem Cells from AML Patients and Healthy Donors Reveals Distinct Patterns of Protein Expression Reflecting Differences in Senescence, Differentiation and Survival Signaling

Interferon-Inducible Protein 16 (IFI-16) Is Upregulated In Chronic Myeloid Leukemia (CML) and Is Involved In Oncogene-Induced Senescence

Glycosylation-Related Gene Expression Is Dysregulated in Multiple Myeloma and Overexpression of the Sialyltransferase ST3GAL6 Is Associated with Inferior Survival.

Glycine Supplementation – A Novel Therapeutic Strategy for Congenital Sideroblastic Anemia.

In Vitro Propagation of Mesenchymal Stromal Cells From Marrow Aspirates of Patients with Chronic Lymphocytic Leukemia Is Dependent Upon Physiologic Oxygen Tension

Prognostic Value of C-Reactive Protein, Lactase Dehydrogenase and Anemia in Recurrent or Refractory Malignant Lymphoma,

Tropomodulin3-Null Mice Are Embryonic Lethal with Anemia and Impaired Definitive Erythropoiesis in the Fetal Liver

Mastl Kinase Gene Disruption Causes Embryonic Lethality.

Tracking Senescence In Human Bone Marrow Stromal Cell (BMSC) Cultures.

Leukemia-Induced Alterations of Bone Marrow Microenvironment Contribute to Leukemogenesis.

A New Molecular and Clinical Prognostic Score for Risk Stratification in CN-AML.

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American Society of Hematology

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American Society of Hematology

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