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Journal Articles

Dual Inhibition of PI3K-δ and PI3K-γ By Duvelisib Eliminates CLL B Cells, Impairs CLL-Supporting Cells, and Overcomes Ibrutinib Resistance in a Patient-Derived Xenograft Model

Shih-Shih Chen, PhD, Jeffery Lorne Kutok, MD PhD, Gerardo Ferrer, PhD, Priyadarshini Ravichandran, Michael Ibrahim, Yasmine Kieso, MSCR, Jacqueline C Barrientos, MD MS, David T. Weaver, PhD, Jonathan A Pachter, PhD, Kanti R Rai, MD, Nicholas Chiorazzi, MD

Blood (2018) 132 (Supplement 1): 4420.

https://doi.org/10.1182/blood-2018-99-109853

Published: 2018

Journal Articles

Contribution of Amino Acid Metabolism to Hematologic Malignancies

Marina Y. Konopleva, MD PhD, Philip L Lorenzi, PhD, Sanaz Ghotbaldini, Yoko Tabe, MD PhD, Tianyu Cai, PhD, Stefano Tiziani, PhD

Blood (2018) 132 (Supplement 1): SCI-10.

https://doi.org/10.1182/blood-2018-99-109469

Published: 2018

Journal Articles

Characterization of Myeloid-Derived Suppressor Cells and Tumor Associated Macrophages Using MultiOmyx TM Hyperplexed Immunofluorescence Assay in Hodgkin Lymphoma

Qingyan Au, PhD, Jun Fang, PhD, Anna Juncker-Jensen, PhD, Judy Kuo, Eric Leones, Flora Sahafi, RaghavKrishna Padmanabhan, PhD, Nicholas Hoe, PhD, Josette William, MD, PhD

Blood (2018) 132 (Supplement 1): 4135.

https://doi.org/10.1182/blood-2018-99-115434

Published: 2018

Journal Articles

LILRB4 Signaling in Leukemia Cells Mediates T Cell Suppression and Tumor Infiltration

Mi Deng, PhD, Xun Gui, PhD, Jaehyup Kim, MDPhD, Junke Zheng, PhD, Ningyan Zhang, PhD, Zhiqiang An, PhD, Chengcheng Zhang, PhD

Blood (2018) 132 (Supplement 1): 5236.

https://doi.org/10.1182/blood-2018-99-120002

Published: 2018

Journal Articles

Knockout Tumor Microenvironment HO-1 Neutralizes Myeloid-Derived Suppressor Cells and Enhances the Antitumor Effect of PD-1 Inhibition in Murine Models of Acute Myeloid Leukemia

Zhen Zhou, Qin Fang, Dan Ma, MD, Danna Wei, Xiuying Hu, Yudan Liao, Jishi Wang, PhD

Blood (2018) 132 (Supplement 1): 2782.

https://doi.org/10.1182/blood-2018-99-117808

Published: 2018

Journal Articles

Loss of HDAC11 Promotes Myeloid-Derived Suppressor Cells Inhibition of T Cell Function in a Murine Lymphoma Microenvironment

Jie Chen, PhD, Fengdong Cheng, MD, Michael Wang, Bachelor of Science, Eva Sahakian, PhD, John J. Powers, BS, Javier Pinilla Ibarz, MD, Mitchell R. Smith, MDPhD, Eduardo Sotomayor, MD

Blood (2018) 132 (Supplement 1): 1105.

https://doi.org/10.1182/blood-2018-99-117007

Published: 2018

Journal Articles

Intravascular Hemolysis Leads to Priapism Phenotype: Experimental Evidence

Fabio H Silva, Beatriz Pereira Bossarino, Fabiano B Calmasini, PhD, Eduardo Costa Alexandre, PhD, Fernando F. Costa, MD, PhD

Blood (2018) 132 (Supplement 1): 1076.

https://doi.org/10.1182/blood-2018-99-115513

Published: 2018

Journal Articles

Runx2 Deficiency in Committed Osteoblasts Promotes Myeloma Cell Homing to and Progression in New Bone Sites

Xiaoxuan Xu, Juan Li, MD, Timothy Trotter, Pramod Gowda, Xiaoxiao Hao, Jacob Calahan, Racquel Innis-Shelton, MD, Amjad Javed, Yang Yang, MD

Blood (2017) 130 (Supplement 1): 126.

https://doi.org/10.1182/blood.V130.Suppl_1.126.126

Published: 2017

Journal Articles

PDE-5 Inhibition Decreases Cancer Tumor Burden through Immunomodulation

Jeff Strojny, BA

Blood (2017) 130 (Supplement 1): 3595.

https://doi.org/10.1182/blood.V130.Suppl_1.3595.3595

Published: 2017

Journal Articles

Arginine Deprivation and Autophagy Sustain Bioenergetics in Multiple Myeloma

Alessandra Romano, MDPhD, Laura Oliva, PhD, Jose Manuel Manteiga, Todoerti Katia, Lorenzo Canziani, Matteo Trudu, Francesca Fontana, Michela Ghizzinardi, Ugo Orfanelli, Magda Marcatti, MD, Fabio Ciceri, MD, Giovanni Tonon, MD PhD, Antonino Neri, MD, Claudio Cerichione, MD PhD, Francesco Di Raimondo, MD, Simone Cenci, MD

Blood (2017) 130 (Supplement 1): 3051.

https://doi.org/10.1182/blood.V130.Suppl_1.3051.3051

Published: 2017

Journal Articles

Arginine Deprivation Sustains Plasma Cell Fitness Via GCN2: A Novel Immuno-Metabolic Check-Point

Alessandra Romano, MDPhD, Ugo Orfanelli, Michela Ghizzinardi, Nunziatina Laura Parrinello, Piera La Cava, Todoerti Katia, Laura Oliva, PhD, Francesca Paradiso, Floriana Cremasco, Daniele Tibullo, Cesarina Giallongo, Concetta Conticello, MD, Magda Marcatti, MD, Fabio Ciceri, MD, Antonino Neri, MD, Claudio Cerichione, MD PhD, Francesco Di Raimondo, MD, Simone Cenci, MD

Blood (2017) 130 (Supplement 1): 1752.

https://doi.org/10.1182/blood.V130.Suppl_1.1752.1752

Published: 2017

Journal Articles

Up-Regulation of iNOS in AML Blasts Creates an Immunosuppressive Microenvironment, Inhibits T-Cell Proliferation and Transforms T-Cells Towards a Tumor-Tolerating Phenotype

Rodrigo Jacamo, PhD, Nguyet-Minh Hoang, B.A., Ahmed Al Rawi, Charlie Ly, BS, Robin Parihar, MDPhD, Teresa McQueen, MS, Peter P. Ruvolo, PhD, Patrick Williams, MD PhD, Gheath Alatrash, DO, PhD, Marina Konopleva, MD PhD, Michael Andreeff, MD PhD

Blood (2017) 130 (Supplement 1): 2443.

https://doi.org/10.1182/blood.V130.Suppl_1.2443.2443

Published: 2017

Journal Articles

Arginase 1 Is a Marker of Myeloid-Mediated Immunosuppression with Prognostic Meaning in Classic Hodgkin Lymphoma

Alessandra Romano, MD PhD, Nunziatina L Parrinello, Daniele Tibullo, PhD, Calogero Vetro, MD, Cesarina Giallongo, Piera La Cava, Annalisa Chiarenza, Loredana Villari, Claudio Tripodo, MD, Giovanna Motta, Laura Caruso, Andrea Gallamini, MD, Stefano A Pileri, Francesco Di Raimondo, MD

Blood (2016) 128 (22): 1770.

https://doi.org/10.1182/blood.V128.22.1770.1770

Published: 2016

Journal Articles

Microenvironmental Links Between TET2/DNMT3A Mutations and Arginase 1 Overexpression in Human MDS/CMML

Alyssa Cull, MSc, Brooke Snetsinger, MSc, David Good, MD, Rena Buckstein, MD, Richard A. Wells, MD DPhil, Michael J. Rauh, MD PhD

Blood (2016) 128 (22): 3164.

https://doi.org/10.1182/blood.V128.22.3164.3164

Published: 2016

Journal Articles

Immune Suppression By High-Density Neutrophils Predicts Short Progression-Free Survival in Multiple Myeloma

Alessandra Romano, MD PhD, Jose Manteiga, PhD, Vittorio Simeon, PhD, Nunziatina L Parrinello, Cesarina Giallongo, Piera La Cava, Concetta Conticello, MD, Daniele Tibullo, PhD, Francesca Fontana, Fabio Ciceri, MD, Floriana Cremasco, Monica Fabbri, Pellegrino Musto, Simone Cenci, MD, Francesco Di Raimondo, MD

Blood (2016) 128 (22): 4459.

https://doi.org/10.1182/blood.V128.22.4459.4459

Published: 2016

Journal Articles

Increased Alternative Macrophage-2 (M2) Polarization with Trib1 Gene over Expression in Myeloma Patients with Progressive Disease and Jak2 Inhibitors Reduce M2 Polarization

Haiming Chen, MD PhD, Mingjie Li, BS, Eric Sanchez, BA, Abigail Gillespie, BS, Cathy Wang, BS, Tiffany Lee, Suzie Vardanyan, MS, Jason Nosrati, BS, Jasmin Cao, Michael Zahab, Puja Mehta, BS, Gigi Garzio, George Tang, PhD, James R. Berenson, MD

Blood (2015) 126 (23): 1011.

https://doi.org/10.1182/blood.V126.23.1011.1011

Published: 2015

Journal Articles

MYd88 Blockade Caused Reduction of PDL1 on Tumor Infiltrating MDSCs in a Murine Model of Melanoma

Parvin Forghani, PhD of Immunology, Edmund K Waller, MD PhD

Blood (2015) 126 (23): 1012.

https://doi.org/10.1182/blood.V126.23.1012.1012

Published: 2015

Journal Articles

Programming of Donor T Cells Using Allogeneic Delta-like Ligand 4-Positive Dendritic Cells to Reduce Gvhd but Retain GVL Activity

Kazuhiro Mochizuki, MD PhD, Lijun Meng, Izumi Mochizuki, MD, Qing Tong, MD, Shan He, Yongnian Liu, Janaki Purushe, Hongxing Sun, Henry Fung, Raza Zaidi, Ran Reshef, MD, Bruce R. Blazar, MD, Hideo Yagita, PhD, Shin Mineishi, MD, Yi Zhang

Blood (2015) 126 (23): 233.

https://doi.org/10.1182/blood.V126.23.233.233

Published: 2015

Journal Articles

Cytotoxicity of the Recombinant Human Arginase (BCT-100) Against Acute Lymphoblastic Leukaemia (ALL)

Francis J Mussai, MA(Oxon), BM, BCh, DPhil, Sarah Booth, BSc, Ashley Vardon, MD, Margaret Ng, MB ChB MDCUHK), Paul Cheng, MDPhD, Carmela De Santo, PhD

Blood (2015) 126 (23): 4916.

https://doi.org/10.1182/blood.V126.23.4916.4916

Published: 2015

Journal Articles

MUC-1 Regulates MiR34a Expression in Acute Myeloid Leukemia Cells Resulting in an Accumulation of Granulocytic Myeloid-Derived Suppressor Cells

Blood (2015) 126 (23): 643.

https://doi.org/10.1182/blood.V126.23.643.643

Published: 2015

NARROW

Dual Inhibition of PI3K-δ and PI3K-γ By Duvelisib Eliminates CLL B Cells, Impairs CLL-Supporting Cells, and Overcomes Ibrutinib Resistance in a Patient-Derived Xenograft Model

Contribution of Amino Acid Metabolism to Hematologic Malignancies

Characterization of Myeloid-Derived Suppressor Cells and Tumor Associated Macrophages Using MultiOmyx TM Hyperplexed Immunofluorescence Assay in Hodgkin Lymphoma

LILRB4 Signaling in Leukemia Cells Mediates T Cell Suppression and Tumor Infiltration

Knockout Tumor Microenvironment HO-1 Neutralizes Myeloid-Derived Suppressor Cells and Enhances the Antitumor Effect of PD-1 Inhibition in Murine Models of Acute Myeloid Leukemia

Loss of HDAC11 Promotes Myeloid-Derived Suppressor Cells Inhibition of T Cell Function in a Murine Lymphoma Microenvironment

Intravascular Hemolysis Leads to Priapism Phenotype: Experimental Evidence

Runx2 Deficiency in Committed Osteoblasts Promotes Myeloma Cell Homing to and Progression in New Bone Sites

PDE-5 Inhibition Decreases Cancer Tumor Burden through Immunomodulation

Arginine Deprivation and Autophagy Sustain Bioenergetics in Multiple Myeloma

Arginine Deprivation Sustains Plasma Cell Fitness Via GCN2: A Novel Immuno-Metabolic Check-Point

Up-Regulation of iNOS in AML Blasts Creates an Immunosuppressive Microenvironment, Inhibits T-Cell Proliferation and Transforms T-Cells Towards a Tumor-Tolerating Phenotype

Arginase 1 Is a Marker of Myeloid-Mediated Immunosuppression with Prognostic Meaning in Classic Hodgkin Lymphoma

Microenvironmental Links Between TET2/DNMT3A Mutations and Arginase 1 Overexpression in Human MDS/CMML

Immune Suppression By High-Density Neutrophils Predicts Short Progression-Free Survival in Multiple Myeloma

Increased Alternative Macrophage-2 (M2) Polarization with Trib1 Gene over Expression in Myeloma Patients with Progressive Disease and Jak2 Inhibitors Reduce M2 Polarization

MYd88 Blockade Caused Reduction of PDL1 on Tumor Infiltrating MDSCs in a Murine Model of Melanoma

Programming of Donor T Cells Using Allogeneic Delta-like Ligand 4-Positive Dendritic Cells to Reduce Gvhd but Retain GVL Activity

Cytotoxicity of the Recombinant Human Arginase (BCT-100) Against Acute Lymphoblastic Leukaemia (ALL)

MUC-1 Regulates MiR34a Expression in Acute Myeloid Leukemia Cells Resulting in an Accumulation of Granulocytic Myeloid-Derived Suppressor Cells

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American Society of Hematology

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ASH Publications

American Society of Hematology

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