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Journal Articles

Novel drivers and modifiers of MPL-dependent oncogenic transformation identified by deep mutational scanning

Jessica L. Bridgford, Su Min Lee, Christine M. M. Lee, Paola Guglielmelli, Elisa Rumi, Daniela Pietra, Stephen Wilcox, Yash Chhabra, Alan F. Rubin, Mario Cazzola, Alessandro M. Vannucchi, Andrew J. Brooks, Matthew E. Call, Melissa J. Call

Blood (2020) 135 (4): 287–292.

https://doi.org/10.1182/blood.2019002561

Published: 2020

Includes: Supplemental data

Journal Articles

Protein Translocation Inhibitors Overcome Cytokine-Induced Glucocorticoid Resistance in T-Cell Acute Lymphoblastic Leukemia

Lauren K. Meyer, Cristina Delgado-Martin, PhD, Phillip P. Sharp, PhD, Dustin McMinn, PhD, Christopher J. Kirk, PhD, Jack Taunton, PhD, Michelle L. Hermiston, MD PhD

Blood (2019) 134 (Supplement_1): 805.

https://doi.org/10.1182/blood-2019-127537

Published: 2019

Journal Articles

Genomic Landscape of Young ATLL Patients Identifies Frequent Targetable CD28 Fusions

Noriaki Yoshida, MD PhD, Kay Shigemori, Samuel Y. Ng, MD PhD, Ajit Nirmal, PhD, Nicolas Donaldson, Nicolas Cordero, Kristen E. Stevenson, MS, Xia Bu, Mai Takeuchi, MD PhD, Koichi Ohshima, MD PhD, Akinori Yoda, PhD, David M Weinstock

Blood (2019) 134 (Supplement_1): 2760.

https://doi.org/10.1182/blood-2019-122525

Published: 2019

Journal Articles

Laminin G Domains of Protein S Bind and Inhibit Fixa

Sabyasachi Chatterjee, PhD MSc, BSc, Amber Sylvain, Undergraduate Student, Satish Pilli, PhD, Whitney Fant, MS, Doerte R. Fricke, MS, Terry Watt, PhD, Rinku Majumder, PhD

Blood (2019) 134 (Supplement_1): 3624.

https://doi.org/10.1182/blood-2019-127112

Published: 2019

Journal Articles

A Novel Platelet-Targeting Fibrinolytic Strategy: Endocytosed Urokinase By Megakaryocytes Is Stored in α-Granules and Is Functional In Vivo in a Murine Model of Thrombosis

Hyunsook Ahn, MSc, John Tkaczynski, BS, Khalil Bdeir, PhD, Victoria Stepanova, Douglas B. Cines, MD, Mortimer Poncz, MD, Sergei Zaitsev

Blood (2019) 134 (Supplement_1): 3627.

https://doi.org/10.1182/blood-2019-124501

Published: 2019

Journal Articles

Pediatric Acute Promyelocytic Leukemia in Brazil: Epidemiology, Molecular Features, and Importance of GST-Theta 1 in Chemotherapy Response and Outcome

Francianne G. Andrade, MSc, PhD, Suellen V. M. Feliciano, MSc, PhD, Ingrid Sardou-Cezar, Gisele D. Brisson, MSc, Filipe V. S. Bueno, MSc, Danielle T. Vianna, MD MSc, Eugênia Terra-Granado, MSc, PhD, Ilana Z. Renault, Marceli O. Santos, MSc, PhD, Elda P. Noronha, MSc, PhD, Joseph L. Wiemels, PhD, Maria S. Pombo-de-Oliveira, MD PhD

Blood (2019) 134 (Supplement_1): 5187.

https://doi.org/10.1182/blood-2019-131529

Published: 2019

Journal Articles

The Mystery of "Magic Blood" - Familial Macrothrombocytopenia Associated with a Novel Variant in GP1BA Gene

Zhaohui Liao Arter, MD, Caitlin Yatogo, MS, CGC, Michael C. Chicka, PhD, Jeffrey L. Berenberg, MD

Blood (2019) 134 (Supplement_1): 2380.

https://doi.org/10.1182/blood-2019-122384

Published: 2019

Journal Articles

Detection of the Genomic Variants in the Paired De Novo-Relapsed Samples with Pan-Cancer Panel and Whole Exome-Seq in Adult B-Cell Acute Lymphoblastic Leukemia

Zheng Ge, MD PhD, Yuka Imamura Kawasawa, PhD, Yan Gu, MD, Qi Han, MD, Jie Zi, Chunhua Song, MD

Blood (2019) 134 (Supplement_1): 5206.

https://doi.org/10.1182/blood-2019-126750

Published: 2019

Journal Articles

Tumor Suppressor Function of Dnmt3b in Hematologic Malignancies Critically Depends on Its Catalytic Activity

Katarina Lopusna, PhD, Pawel Nowialis, PhD, Staci L. Haney, PhD, Ajay Abraham, PhD, Jana Opavska, Rene Opavsky, PhD

Blood (2019) 134 (Supplement_1): 3788.

https://doi.org/10.1182/blood-2019-130857

Published: 2019

Journal Articles

MLL1 Modulates IgM and Inflammatory Cytokines in Waldenstrom's Macroglobulinemia

Mona Karbalivand, MSc, BSc, Weiguo Han, PhD, Luciana L Almada, PhD, Stephen M Ansell, MD PhD, Martin Fernandez-Zapico, MD, Sherine F Elsawa, PhD

Blood (2019) 134 (Supplement_1): 3966.

https://doi.org/10.1182/blood-2019-125833

Published: 2019

Journal Articles

Combination of Gatekeeper Mutations and Cysteine 481 Replacement Causes Super Resistance to the Irreversible BTK Inhibitors Ibrutinib, Acalabrutinib and Zanubrutinib

Hernando Yesid Estupiñan Velasquez, Yuye Shi, MD PhD, Dara K. Mohammad, PhD, Qing Wang, Mauno Vihinen, PhD, Rula Zain, PhD, Anna Berglöf, PhD VMD, Edvard CI Smith, MD PhD

Blood (2019) 134 (Supplement_1): 5759.

https://doi.org/10.1182/blood-2019-123398

Published: 2019

Journal Articles

Novel Recurrent Germline JAK2 G571S Variant in Childhood Acute B-Lymphoblastic Leukemia: A Double Hit One Pathway Scenario

Franziska Auer, PhD, Minhui Lin, PhD, Karin Nebral, PhD, Christoph G. W. Gertzen, PhD, Oskar A. Haas, MD, Michaela Kuhlen, MD, Holger Gohlke, PhD, Shai Izraeli, MD, Jan Trka, MD PhD, Jianda Hu, PhD, Arndt Borkhardt, MD, Julia Hauer, MD

Blood (2018) 132 (Supplement 1): 387.

https://doi.org/10.1182/blood-2018-99-115293

Published: 2018

Journal Articles

A Novel Lysine to Arginine Substitution at Position 301 Enhances Activity of Factor IX

Daniel Verhoef, Jonathan H. Foley, Andrew Goodale, Emma Macrae, Jenny McIntosh, PhD, Romuald Corbau, PhD, Keith Gomez, Anne Riddell, Amit C Nathwani, MD PhD

Blood (2018) 132 (Supplement 1): 3772.

https://doi.org/10.1182/blood-2018-99-112832

Published: 2018

Journal Articles

Opportunities for Improvement: The Lot of the Inhibitor Patient Is Not a Happy One

Frank V. McL. Booth, MA MSc BM BCh, Johnny Mahlangu, Howard Levy, PhD MBBChir

Blood (2018) 132 (Supplement 1): 5040.

https://doi.org/10.1182/blood-2018-99-111720

Published: 2018

Journal Articles

Epigenetic Modifier Mutations in the LL-100 Panel

Hilmar Quentmeier, PhD, Claudia Pommerenke, PhD, Hans G. Drexler, MD PhD

Blood (2018) 132 (Supplement 1): 5271.

https://doi.org/10.1182/blood-2018-99-110060

Published: 2018

Journal Articles

RPPA-Profiling Identifies Patients with Low Phosphorylation Levels of HSF1 at Serine 326 As Potential Candidate for Bortezomib Treatment in Addition to Standard Therapy in Pediatric Acute Myeloid Leukemia

Fieke W Hoff, BSc, Wendy Hu, PhD, Yihua Qiu, Alan S Gamis, MD MPH, Richard Aplenc, MD PhD, E. Anders Kolb, MD, Todd A Alonzo, PhD, Amina A Qutub, PhD, Eveline S. de Bont, MD, Sophia W.M. Bruggeman, PhD, Steven M. Kornblau, MD, Terzah M. Horton, MD PhD

Blood (2018) 132 (Supplement 1): 293.

https://doi.org/10.1182/blood-2018-99-110730

Published: 2018

Journal Articles

Novel Multidisciplinary Comprehensive Clinic Program Improves Patient Compliance, Patient Satisfaction and Health Maintainance Outcomes in the Outpatient Setting for Patients with Severe Sickle Cell Disease

Paul Gordon, MBBS, Ramamoorthy Nagasubramanian, MD, Ashley Parker, BSN, RN, Lindsay Clark, BSN RN, Hayley Balmer, Caleb Gordon, Dorothea N. Douglas, MD

Blood (2018) 132 (Supplement 1): 4937.

https://doi.org/10.1182/blood-2018-99-110112

Published: 2018

Journal Articles

Characterizing the Immunogenicity of DM-Sensitive and DM-Resistant Antigens

Anna Luise Bernhardt, Sascha Kretschmann, PhD, Judith Bausenwein, Heidi Balzer, Andreas Mackensen, MD, Anita Natalie Kremer, MD PhD

Blood (2018) 132 (Supplement 1): 3310.

https://doi.org/10.1182/blood-2018-99-112103

Published: 2018

Journal Articles

Genetic Validation of the Palmitoylation/Depalmitoylation Cycle As a Drug Target in NRAS Mutant Hematologic Malignancies In Vivo

Noemi A. Zambetti, PhD, Ari J. Firestone, PhD, Jasmine C. Wong, PhD, Amanda Long, BA, Anagha Inguva, BA, Radu M. Suciu, B.Sc., Benjamin F. Cravatt, PhD, Kevin M. Haigis, PhD, Kevin M. Shannon, MD

Blood (2017) 130 (Supplement 1): 1221.

https://doi.org/10.1182/blood.V130.Suppl_1.1221.1221

Published: 2017

Journal Articles

Recovery of Thymic Function after Allogeneic Hematopoietic Stem Cell Transplantation in with Sickle Cell Anemia Patients

Luciana Ribeiro Jarduli, BPharm, MMSc, Emmanuel Clave, PhD, Isabelle Fournier, Dimas Tadeu Covas, MD PhD, Ana Cristina Silva Pinto, MD PhD, Belinda Pinto Simões, MD PhD, Antoine Toubert, MD PhD, Kelen Cristina Ribeiro Malmegrim de Farias, PhD

Blood (2017) 130 (Supplement 1): 3261.

https://doi.org/10.1182/blood.V130.Suppl_1.3261.3261

Published: 2017

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Novel drivers and modifiers of MPL-dependent oncogenic transformation identified by deep mutational scanning

Protein Translocation Inhibitors Overcome Cytokine-Induced Glucocorticoid Resistance in T-Cell Acute Lymphoblastic Leukemia

Genomic Landscape of Young ATLL Patients Identifies Frequent Targetable CD28 Fusions

Laminin G Domains of Protein S Bind and Inhibit Fixa

A Novel Platelet-Targeting Fibrinolytic Strategy: Endocytosed Urokinase By Megakaryocytes Is Stored in α-Granules and Is Functional In Vivo in a Murine Model of Thrombosis

Pediatric Acute Promyelocytic Leukemia in Brazil: Epidemiology, Molecular Features, and Importance of GST-Theta 1 in Chemotherapy Response and Outcome

The Mystery of "Magic Blood" - Familial Macrothrombocytopenia Associated with a Novel Variant in GP1BA Gene

Detection of the Genomic Variants in the Paired De Novo-Relapsed Samples with Pan-Cancer Panel and Whole Exome-Seq in Adult B-Cell Acute Lymphoblastic Leukemia

Tumor Suppressor Function of Dnmt3b in Hematologic Malignancies Critically Depends on Its Catalytic Activity

MLL1 Modulates IgM and Inflammatory Cytokines in Waldenstrom's Macroglobulinemia

Combination of Gatekeeper Mutations and Cysteine 481 Replacement Causes Super Resistance to the Irreversible BTK Inhibitors Ibrutinib, Acalabrutinib and Zanubrutinib

Novel Recurrent Germline JAK2 G571S Variant in Childhood Acute B-Lymphoblastic Leukemia: A Double Hit One Pathway Scenario

A Novel Lysine to Arginine Substitution at Position 301 Enhances Activity of Factor IX

Opportunities for Improvement: The Lot of the Inhibitor Patient Is Not a Happy One

Epigenetic Modifier Mutations in the LL-100 Panel

RPPA-Profiling Identifies Patients with Low Phosphorylation Levels of HSF1 at Serine 326 As Potential Candidate for Bortezomib Treatment in Addition to Standard Therapy in Pediatric Acute Myeloid Leukemia

Novel Multidisciplinary Comprehensive Clinic Program Improves Patient Compliance, Patient Satisfaction and Health Maintainance Outcomes in the Outpatient Setting for Patients with Severe Sickle Cell Disease

Characterizing the Immunogenicity of DM-Sensitive and DM-Resistant Antigens

Genetic Validation of the Palmitoylation/Depalmitoylation Cycle As a Drug Target in NRAS Mutant Hematologic Malignancies In Vivo

Recovery of Thymic Function after Allogeneic Hematopoietic Stem Cell Transplantation in with Sickle Cell Anemia Patients

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