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Journal Articles

Inflammatory Cytokine Responsive Enzymatic Mutagenesis Fuels Myeloproliferative Neoplasm Pre-Leukemia Stem Cell Evolution

Catriona Jamieson, MD PhD, Qingfei Jiang, PhD, Frida Holm, PhD, Jane Isquith, MS, Adam Mark, Cayla Mason, BS, Wenxue Ma, MD PhD, Raymond H Diep, Jessica Pham, B.S., Eduardo Reynoso Moreno, PhD, Chanond A Nasamran, Xu Guorong, Amanda Birmingham, Leslie A Crews, PhD, Ludmil Alexandrov, Gabriel Pineda, PhD, Thomas Whisenant, Kathleen M Fisch

Blood (2019) 134 (Supplement_1): 3780.

https://doi.org/10.1182/blood-2019-131510

Published: 2019

Journal Articles

The RNA Binding Protein MSI2 Has Increased RNA Binding Activity in Leukemic Stem Cells Compared to Normal Hematopoietic Stem Cells

Diu Nguyen, PhD, Yuheng Lu, PhD, Zi-ning Choo, Christopher Chin, Camila Prieto, BA, Saroj Gourkanti, BA, Christina Leslie, PhD, Michael G. Kharas, PhD

Blood (2018) 132 (Supplement 1): 884.

https://doi.org/10.1182/blood-2018-99-118949

Published: 2018

Journal Articles

RNA Editing of Tumor Suppressor Mir-26a Promotes Malignant Progenitor Propagation in Chronic Myeloid Leukemia

Raymond H Diep, Qingfei Jiang, PhD, Jane Isquith, MS, Maria A. Zipeto, PhD, Jessica Pham, Nathan Delos Santos, BS, Julisia Chau, B.S., Sheldon Morris, MD MPH, Catriona Jamieson, MD PhD

Blood (2018) 132 (Supplement 1): 2611.

https://doi.org/10.1182/blood-2018-99-116988

Published: 2018

Journal Articles

Umbilical Cord Blood Mononuclear Cells for Ex-Vivo Gene Therapy

Farid V. Bashirov, Ilnur I. Salafutdinov, PhD, Michail E. Sokolov, Andrew A. Izmailov, MD, Vage A. Markosyan, Filip O. Fadeev, Albert Rizvanov, DSc, PhD, Rustem I. Islamov

Blood (2018) 132 (Supplement 1): 5797.

https://doi.org/10.1182/blood-2018-99-113462

Published: 2018

Journal Articles

Genetic Modulation of Adenosine-to-Inosine RNA Editing Selectively Disrupts Inflammasome and Extracellular Matrix Genes in Multiple Myeloma

Leslie A Crews, PhD, Phoebe Mondala, BS, Elisa Lazzari, PhD, Gabriel Pineda, PhD, Christina Wu, PhD, Caitlin L. Costello, MD, Catriona Jamieson, MD PhD

Blood (2018) 132 (Supplement 1): 1324.

https://doi.org/10.1182/blood-2018-99-120326

Published: 2018

Journal Articles

Hepcidin Predicts Decrease in Erythroid Expansion in Sickle Cell Disease Patients Treated with Inhaled Steroids

Marc Ruiz Martinez, PhD, Wenbin An, MD, Maria Feola, PhD, Jeffrey A. Glassberg, MD, Yelena Ginzburg, MD

Blood (2018) 132 (Supplement 1): 2339.

https://doi.org/10.1182/blood-2018-99-115234

Published: 2018

Journal Articles

Fetal Erythropoiesis Is Defective in Rpl11 Heterozygous Mice and Increases in Severity in Young Animals

Dolly Thomas, PhD, Cailin Joyce, PhD, Robert A. Redd, MS, Bertil Glader, MD, Steven Ellis, PhD, Donna S. Neuberg, ScD, Meaghan McGuinness, BS, Colin A. Sieff, MB, BCh, Carl D. Novina, MD PhD

Blood (2017) 130 (Supplement 1): 872.

https://doi.org/10.1182/blood.V130.Suppl_1.872.872

Published: 2017

Journal Articles

Plasma Fms-Related Tyrosine Kinase 3 Ligand (Flt3L) Levels at Diagnosis Correlate with Treatment Response in Chronic Myeloid Leukemia

Bhagwan Yadav, PhD, Mette Ilander, PhD, Anna Kreutzman, PhD, Henrik Hjorth-Hansen, MD, Satu Mustjoki, MDPhD

Blood (2017) 130 (Supplement 1): 1602.

https://doi.org/10.1182/blood.V130.Suppl_1.1602.1602

Published: 2017

Journal Articles

Adar-Mediated Aberrant a-to-I RNA Editing Is Driven By 1q Amplification and Contributes to Proteasome Inhibitor Resistance in Multiple Myeloma

Alessandro Lagana, PhD, Violetta Leshchenko, PhD, David Melnekoff, BS, MSc, Itai Beno, PhD, Deepak Perumal, PhD, Jonathan Keats, PhD, Mary DeRome, MS, Jennifer Yesil, MS, Daniel Auclair, PhD, Deepu Madduri, MD, Ajai Chari, MD, Hearn Jay Cho, MD PhD, Bart Barlogie, MD PhD, Sundar Jagannath, MD, Joel Dudley, PhD, Samir Parekh, MD

Blood (2017) 130 (Supplement 1): 268.

https://doi.org/10.1182/blood.V130.Suppl_1.268.268

Published: 2017

Journal Articles

Large Deletions and Novel Mutations in Genes Coding for Ribosomal Proteins ( RPL11 , RPL35A , RPS19 ) in the Czech National Registry of Diamond-Blackfan Anemia (DBA)

Jana Volejnikova, MD, Petr Vojta, MSc, Zuzana Maceckova, MSc, Pavla Koralkova, MSc, Helena Urbankova, MSc, PhD, Monika Horvathova, MSc, PhD, Barbora Ludikova, MD PhD, Martina Sukova, MD, Pavel Timr, MD, Marian Hajduch, MD PhD, Dagmar Pospisilova, Prof. MD PhD

Blood (2017) 130 (Supplement 1): 3485.

https://doi.org/10.1182/blood.V130.Suppl_1.3485.3485

Published: 2017

Journal Articles

ADAR1-MediatedGLI1 Editing Promotes Malignant Self-Renewal in Multiple Myeloma

Leslie Crews, PhD, Elisa Lazzari, PhD, Phoebe Mondala, BS, Nathan Delos Santos, BS, Amber Miller, PhD BA, Gabriel Pineda, PhD, Qingfei Jiang, PhD, Heather Leu, BS, Shawn Ali, BA, Anusha Preethi Ganesan, MD PhD, Christina Wu, PhD, Caitlin L. Costello, MD, Mark D. Minden, MD PhD, Raffaella Chiaramonte, PhD, A. Keith Stewart, MBChB, MBA, Catriona Jamieson, MD PhD

Blood (2017) 130 (Supplement 1): 1204.

https://doi.org/10.1182/blood.V130.Suppl_1.1204.1204

Published: 2017

Journal Articles

Erythrocyte Adenosine Deaminase Levels Are Elevated in Classic Diamond Blackfan Anemia but Not in the 5q- Syndrome

Anupama Narla, MD, Natalie Louise Davis, MD, Corinne LaVasseur, BA, Carolyn Wong, Bertil Glader, MD PhD

Blood (2016) 128 (22): 1501.

https://doi.org/10.1182/blood.V128.22.1501.1501

Published: 2016

Journal Articles

Decoding the RNA Editome of Normal Versus Malignant Progenitor Cell Aging Short Title: RNA Editing in Normal Aging and MDS/AML Stem Cells

Leslie A Crews, PhD, Qingfei Jiang, PhD, Larisa Balaian, PhD, Heather Leu, BS, Nathan Delos Santos, Angela C Court, Anil Sadarangani, PhD, Sheldon Morris, MD, Rainer F. Storb, MD, Anna Kulidjian, MD, Edward D. Ball, MD, Catriona Jamieson, MD PhD

Blood (2016) 128 (22): 1519.

https://doi.org/10.1182/blood.V128.22.1519.1519

Published: 2016

Journal Articles

Two Novel Mutations in Ribosomal Proteins in the Czech National Diamond-Blackfan Anemia Registry

Zuzana Maceckova, MSc, Pavla Koralkova, MSc, Jana Volejnikova, MD PhD, Petr Vojta, MSc, Alexandra Jungova, MD, Zuzana Saxova, MSc, Renata Mojzikova, MSc, PhD, Marie Jarosova, MSc PhD, Ivana Hadacova, MD, Marian Hajduch, MD PhD, Monika Horvathova, MSc, PhD, Dagmar Pospisilova, MD PhD

Blood (2016) 128 (22): 3903.

https://doi.org/10.1182/blood.V128.22.3903.3903

Published: 2016

Journal Articles

Aberrant a-to-I RNA Editing and Prognostic Impact of Adar in Multiple Myeloma Patients with 1q Amplification

Alessandro Lagana, PhD, Deepak Perumal, PhD, Violetta V Leshchenko, PhD, Pei-Yu Kuo, MS, Brian Kidd, PhD, Jonathan J Keats, PhD, Mary Derome, MS, Jennifer Yesil, MS, Daniel Auclair, PhD, Deepu Madduri, Ajai Chari, MD, Hearn Jay Cho, MD PhD, Bart Barlogie, MD PhD, Sundar Jagannath, MD, Joel Dudley, PhD, Samir Parekh, MD

Blood (2016) 128 (22): 357.

https://doi.org/10.1182/blood.V128.22.357.357

Published: 2016

Journal Articles

The Novel Missense Mutation of GATA1 Caused Red Cell Adenosine Deaminase Overproduction Associated with Congenital Hemolytic Anemia

Hiromi Ogura, MD PhD, Toshiyuki Yamamoto, MD PhD, Taiju Utsugisawa, MD PhD, Takako Aoki, MLS, Takuya Iwasaki, MLS, Yumiko Ondo, MLS, Takahiro Kawakami, MD PhD, Shinichiro Nakagawa, MD PhD, Shuichi Ozono, MD PhD, Hiroko Inada, MD PhD, Hitoshi Kanno, MD PhD

Blood (2016) 128 (22): 400.

https://doi.org/10.1182/blood.V128.22.400.400

Published: 2016

Journal Articles

RNA Editing Enzyme ADAR1 Accelerates Normal Hematopoiesis Cell Cycle By Regulating microRNA Biogenesis

Qingfei Jiang, PhD, Maria A. Zipeto, PhD, Nathaniel Delos Santos, BS, Heather Leu, BS, Jane Isquith, MS, Etienne Atien, BS, Catriona Jamieson, MD PhD

Blood (2016) 128 (22): 887.

https://doi.org/10.1182/blood.V128.22.887.887

Published: 2016

Journal Articles

Update on the safety and efficacy of retroviral gene therapy for immunodeficiency due to adenosine deaminase deficiency

Blood (2016) 128 (1): 45–54.

https://doi.org/10.1182/blood-2016-01-688226

Published: 2016

Includes: Supplemental data

Journal Articles

Adenosine Deaminase 2 Deficiency As a Cause of Pure Red Cell Aplasia Mimicking Diamond Blackfan Anemia

Ghadir S. Sasa, MD, M. Tarek Elghetany, MD, Katie Bergstrom, Sarah Nicholas, MD, Ryan Himes, MD, Robert A. Krance, MD, Michael Hershfield, MD PhD, Joris van Montfrans, MD PhD, Alison Bertuch, MD PhD

Blood (2015) 126 (23): 3615.

https://doi.org/10.1182/blood.V126.23.3615.3615

Published: 2015

Journal Articles

Pentostatin Therapy for Steroid-Refractory Acute Graft Versus Host Disease: Identifying Those Who May Benefit

Brittany Knick Ragon, MD, Alison M Gulbis, Rima M Saliba, PhD, Julianne Chen, Gabriela Rondon, MD, Uday R. Popat, MD, Yago Nieto, MD PhD, Betul Oran, MD, Amanda L. Olson, MD, Krina Patel, MD, Chitra M. Hosing, MD, Muzaffar H. Qazilbash, MD, Nina Shah, MD, Partow Kebriaei, MD, Elizabeth J. Shpall, MD, Richard E. Champlin, MD, Amin M. Alousi, MD

Blood (2015) 126 (23): 3136.

https://doi.org/10.1182/blood.V126.23.3136.3136

Published: 2015

NARROW

Inflammatory Cytokine Responsive Enzymatic Mutagenesis Fuels Myeloproliferative Neoplasm Pre-Leukemia Stem Cell Evolution

The RNA Binding Protein MSI2 Has Increased RNA Binding Activity in Leukemic Stem Cells Compared to Normal Hematopoietic Stem Cells

RNA Editing of Tumor Suppressor Mir-26a Promotes Malignant Progenitor Propagation in Chronic Myeloid Leukemia

Umbilical Cord Blood Mononuclear Cells for Ex-Vivo Gene Therapy

Genetic Modulation of Adenosine-to-Inosine RNA Editing Selectively Disrupts Inflammasome and Extracellular Matrix Genes in Multiple Myeloma

Hepcidin Predicts Decrease in Erythroid Expansion in Sickle Cell Disease Patients Treated with Inhaled Steroids

Fetal Erythropoiesis Is Defective in Rpl11 Heterozygous Mice and Increases in Severity in Young Animals

Plasma Fms-Related Tyrosine Kinase 3 Ligand (Flt3L) Levels at Diagnosis Correlate with Treatment Response in Chronic Myeloid Leukemia

Adar-Mediated Aberrant a-to-I RNA Editing Is Driven By 1q Amplification and Contributes to Proteasome Inhibitor Resistance in Multiple Myeloma

Large Deletions and Novel Mutations in Genes Coding for Ribosomal Proteins ( RPL11 , RPL35A , RPS19 ) in the Czech National Registry of Diamond-Blackfan Anemia (DBA)

ADAR1-MediatedGLI1 Editing Promotes Malignant Self-Renewal in Multiple Myeloma

Erythrocyte Adenosine Deaminase Levels Are Elevated in Classic Diamond Blackfan Anemia but Not in the 5q- Syndrome

Decoding the RNA Editome of Normal Versus Malignant Progenitor Cell Aging Short Title: RNA Editing in Normal Aging and MDS/AML Stem Cells

Two Novel Mutations in Ribosomal Proteins in the Czech National Diamond-Blackfan Anemia Registry

Aberrant a-to-I RNA Editing and Prognostic Impact of Adar in Multiple Myeloma Patients with 1q Amplification

The Novel Missense Mutation of GATA1 Caused Red Cell Adenosine Deaminase Overproduction Associated with Congenital Hemolytic Anemia

RNA Editing Enzyme ADAR1 Accelerates Normal Hematopoiesis Cell Cycle By Regulating microRNA Biogenesis

Update on the safety and efficacy of retroviral gene therapy for immunodeficiency due to adenosine deaminase deficiency

Adenosine Deaminase 2 Deficiency As a Cause of Pure Red Cell Aplasia Mimicking Diamond Blackfan Anemia

Pentostatin Therapy for Steroid-Refractory Acute Graft Versus Host Disease: Identifying Those Who May Benefit

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American Society of Hematology

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