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Journal Articles

SASH3 variants cause a novel form of X-linked combined immunodeficiency with immune dysregulation

Blood (2021) 138 (12): 1019–1033.

https://doi.org/10.1182/blood.2020008629

Published: 2021

Includes: Supplemental data

Journal Articles

Proteomic Analysis of Mitochondrial Membrane Protein FAM210B in Erythroid Cells

Chie Suzuki, Tohru Fujiwara, MD PhD, Hiroki Shima, Koya Ono, MD, Kei Saito, Noriko Fukuhara, MD PhD, Yasushi Onishi, MD PhD, Hisayuki Yokoyama, MD PhD, Shinichi Fujimaki, Yukio Nakamura, MD PhD, Hideo Harigae, MD PhD

Blood (2019) 134 (Supplement_1): 3523.

https://doi.org/10.1182/blood-2019-122618

Published: 2019

Journal Articles

Cooperativity between Flt3/Syk and Proteasome Inhibitors in Flt3mutant/Wildtype AML, By Acting on the Oxphos and Wnt Endpoints of Syk and p62SQSTM1 Pathways Prohibits Protective Autophagy; While Downregulation of NRF2, NQO1, Jun, and b-Catenin Bypasses Interfering RAS or WT1 Co-Mutations

Sravanti Rangaraju, MBBS, Silvia Marino, PhD, G. David Roodman, MD PhD, Larry D. Cripe, MD, Baskar Ramdas, PhD, Lakshmi Reddy Palam, PhD, Katie J Sargent, RN, Hamid Sayar, MD MSc, Heiko Konig, MD PhD, Reuben Kapur, PhD, H. Scott Boswell, MD

Blood (2019) 134 (Supplement_1): 5051.

https://doi.org/10.1182/blood-2019-124384

Published: 2019

Journal Articles

Quantitative Investigation of Pharmacologically Modulated Signaling and Efficacy in ABC DLBCL Using a Systems Pharmacology Model

Kosinsky Yuri, PhD, Lulu Chu, PhD, Millie Shah, PhD, Karthick Vishwanathan, PhD, Connie Larsson, PhD, Andrew Bloecher, PhD, Brandon Willis, PhD, Hannah Dry, BSc, Kirill Peskov, PhD, Joseph Ware, PhD, Andrew Mortlock, PhD, Gabriel Helmlinger, PhD

Blood (2019) 134 (Supplement_1): 5304.

https://doi.org/10.1182/blood-2019-130879

Published: 2019

Journal Articles

O-Glcnacylation Is Essential for Erythropoiesis

Matthew P Parker, BS, Halyna Fedosyuk, MS, Lesya V Novikova, PhD, Zhen Zhang, PhD, Chad Slawson, PhD, Kenneth R Peterson, PhD

Blood (2019) 134 (Supplement_1): 2218.

https://doi.org/10.1182/blood-2019-129468

Published: 2019

Journal Articles

ANKRD26 Coding Variants Presenting with Giant Platelets and a Predisposition to Myeloid Neoplasia

Teodora Kuzmanovic, Bhumika J. Patel, MD, Jibran Durrani, Hassan Awada, MD, Cassandra M Kerr, MS, Bartlomiej P. Przychodzen, Samuel Li, BA, Seth J. Corey, MD, Sudipto Mukherjee, MD PhD MPH, Anjali S. Advani, MD, Aziz Nazha, MD, Aaron T. Gerds, MD MS, Hetty E. Carraway, MD MBA, Thomas Laframboise, PhD, Mikkael A. Sekeres, MD MS, Jaroslaw P. Maciejewski, MD PhD

Blood (2019) 134 (Supplement_1): 4233.

https://doi.org/10.1182/blood-2019-130520

Published: 2019

Journal Articles

Targeting PRMT1-mediated FLT3 methylation disrupts maintenance of MLL -rearranged acute lymphoblastic leukemia

Blood (2019) 134 (15): 1257–1268.

https://doi.org/10.1182/blood.2019002457

Published: 2019

Includes: Supplemental data

Journal Articles

The BRISC deubiquitinating enzyme complex limits hematopoietic stem cell expansion by regulating JAK2 K63-ubiquitination

Ryan Donaghy, Xu Han, Krasimira Rozenova, Kaosheng Lv, Qinqin Jiang, Miriam Doepner, Roger A. Greenberg, Wei Tong

Blood (2019) 133 (14): 1560–1571.

https://doi.org/10.1182/blood-2018-10-877563

Published: 2019

Includes: Supplemental data

Journal Articles

Clinical Significance of Novel SH2B3 Mutations in Adult Chinese Acute Lymphoblastic Leukemia Patients

Yan Gu, MD, Qi Han, MD, Mary McGrath, Soumya Iyer, Chunhua Song, MD PhD, Zheng Ge, MD PhD

Blood (2018) 132 (Supplement 1): 2657.

https://doi.org/10.1182/blood-2018-99-110793

Published: 2018

Journal Articles

Role of Signal Transducing Adaptor Protein-1 (STAP-1) in Chronic Myelogenous Leukemia Stem Cells

Jun Toda, MD, Michiko Ichii, MD PhD, Hirohiko Shibayama, MD PhD, Hideaki Saito, MD, Yuichi Kitai, Ryuta Muromoto, Jun-ichi Kashiwakura, Kodai Saitoh, Tadashi Matsuda, Kenji Oritani, MD PhD, Yuzuru Kanakura, MD PhD

Blood (2018) 132 (Supplement 1): 4245.

https://doi.org/10.1182/blood-2018-99-113725

Published: 2018

Journal Articles

Signal Transducing Adaptor Protein (STAP) Family Accelerates Gut and Thymic Graft-Versus-Host-Disease in Murine Model

Hideaki Saito, MD, Michiko Ichii, MD PhD, Jun Toda, MD, Yuichi Kitai, Ryuta Muromoto, Jun-ichi Kashiwakura, Kodai Saitoh, Hirohiko Shibayama, MD PhD, Tadashi Matsuda, Kenji Oritani, MD PhD, Yuzuru Kanakura, MD PhD

Blood (2018) 132 (Supplement 1): 4516.

https://doi.org/10.1182/blood-2018-99-112803

Published: 2018

Journal Articles

Preclinical Activity of IRAK4 Kinase Inhibitor CA-4948 Alone or in Combination with Targeted Therapies and Preliminary Phase 1 Clinical Results in Non-Hodgkin Lymphoma

Robert N Booher, PhD, Grzegorz S. Nowakowski, MD, Krish Patel, MD, Matthew A. Lunning, DO, Maria Elena S. Samson, B.S., Ruzanna Atoyan, MD, Anna W Ma, MS, Guang-Xin Xu, BS, Steven Dellarocca, B.S., Holly Modafferi, BS, Mylissa Borek, B.S., Zhidong Zhang, PhD, Jefferson Parker, PhD, Duncan Whitney, PhD, Hongwei Wang, MD, David P Tuck, MD, Anas Younes, MD

Blood (2018) 132 (Supplement 1): 4168.

https://doi.org/10.1182/blood-2018-99-117383

Published: 2018

Journal Articles

Domain-Focused CRISPR-Cas9 Screen Identifies the E3 Ubiquitin Ligase Substrate Adaptor Protein SPOP as a Novel Repressor of Fetal Hemoglobin

Xianjiang Lan, PhD, Eugene Khandros, MD PhD, Jeremy D. Grevet, BA, Scott A. Peslak, MD, Saurabh Bhardwaj, PhD, Cheryl A. Keller, PhD, Belinda Giardine, Ben A. Garcia, PhD, Ross C. Hardison, PhD, Junwei Shi, PhD, Gerd A. Blobel, MD PhD

Blood (2018) 132 (Supplement 1): 414.

https://doi.org/10.1182/blood-2018-99-119518

Published: 2018

Journal Articles

Targeting IRAK4 Disrupts Inflammatory Pathways and Delays Tumor Development in Chronic Lymphocytic Leukemia

Neus Giménez Carabaza, B.Pharm, Rosich Laia, PhD, Schulz Ralph, MS, Higashi Morihiro, MD, Marta Aymerich, Neus Villamor, PhD, Julio Delgado, MD, Manel Juan, MD, Monica Lopez-Guerra, PhD, Elias Campo, Martina Seiffert, PhD, Dolors Colomer, PhD

Blood (2018) 132 (Supplement 1): 2650.

https://doi.org/10.1182/blood-2018-99-115999

Published: 2018

Journal Articles

Target of Erythropoietin, Fam210b , Regulates Erythroid Heme Synthesis By Control of Mitochondrial Iron Import and Regulation of Fech Activity

Blood (2018) 132 (Supplement 1): 849.

https://doi.org/10.1182/blood-2018-99-120299

Published: 2018

Journal Articles

Lnk/Sh2b3 Deficiency Restores Hematopoietic Stem Cell Function and Genome Integrity in Fanconi Anemia

Wei Tong, PhD, Joanna Balcerek, PhD, Jing Jiang, PhD, Nicholas Holdreith, MS, Qinqin Jiang, Krasimira A. Rozenova, PhD, Weihua Li, Roger A Greenberg

Blood (2017) 130 (Supplement 1): 1134.

https://doi.org/10.1182/blood.V130.Suppl_1.1134.1134

Published: 2017

Journal Articles

Unique Roles for Grb2-Associated Binding (Gab) Adaptors in Hematopoietic Stem Cell Homeostasis and Repopulation

Zhengqi Wang, PhD, Gen-sheng Feng, PhD, Kevin D. Bunting, PhD

Blood (2017) 130 (Supplement 1): 2431.

https://doi.org/10.1182/blood.V130.Suppl_1.2431.2431

Published: 2017

Journal Articles

Signal-Transducing Adaptor Protein-2 Blocks B Cell Recovery Under Hematological Stress at Pre-B Stage Via TLR4 Signaling

Michiko Ichii, MD PhD, Kenji Oritani, MD PhD, Hirohiko Shibayama, MD PhD, Jun Toda, MD, Hideaki Saito, MD, Yuichi Kitai, Ryuta Muromoto, Jun-ichi Kashiwakura, Kodai Saitoh, Tadashi Matsuda, Yuzuru Kanakura, MD PhD

Blood (2017) 130 (Supplement 1): 1155.

https://doi.org/10.1182/blood.V130.Suppl_1.1155.1155

Published: 2017

Journal Articles

Canonical Inflammasome Formation in Monocytes of Sickle Cell Anemia Patients

Rafaela Mendonça, BS, Karla P.V Ferro, PhD, Flávia Costa Leonardo, PhD, Juliete A.F. Silva, PhD, Fernando Vieira Pericole, MD PhD, Sara T Olalla Saad, MD PhD, Fernando F. Costa, MD, PhD, Nicola Conran, PhD

Blood (2017) 130 (Supplement 1): 2233.

https://doi.org/10.1182/blood.V130.Suppl_1.2233.2233

Published: 2017

Journal Articles

The NLRP3 Inflammasome in Platelets Is Upregulated in Sickle Cell Disease and Promotes Platelet Aggregation and In Vitro Thrombosis

Sebastian Vogel, MD PhD, Taruna Arora, MD, Xunde Wang, PhD, Luis E. Almeida, MD PhD, Zenaide Quezado, MD, Swee Lay Thein, DSc,FRCP,FRCPath,MBBS,MRCPath,MRCP

Blood (2017) 130 (Supplement 1): 2234.

https://doi.org/10.1182/blood.V130.Suppl_1.2234.2234

Published: 2017

NARROW

SASH3 variants cause a novel form of X-linked combined immunodeficiency with immune dysregulation

Proteomic Analysis of Mitochondrial Membrane Protein FAM210B in Erythroid Cells

Cooperativity between Flt3/Syk and Proteasome Inhibitors in Flt3mutant/Wildtype AML, By Acting on the Oxphos and Wnt Endpoints of Syk and p62SQSTM1 Pathways Prohibits Protective Autophagy; While Downregulation of NRF2, NQO1, Jun, and b-Catenin Bypasses Interfering RAS or WT1 Co-Mutations

Quantitative Investigation of Pharmacologically Modulated Signaling and Efficacy in ABC DLBCL Using a Systems Pharmacology Model

O-Glcnacylation Is Essential for Erythropoiesis

ANKRD26 Coding Variants Presenting with Giant Platelets and a Predisposition to Myeloid Neoplasia

Targeting PRMT1-mediated FLT3 methylation disrupts maintenance of MLL -rearranged acute lymphoblastic leukemia

The BRISC deubiquitinating enzyme complex limits hematopoietic stem cell expansion by regulating JAK2 K63-ubiquitination

Clinical Significance of Novel SH2B3 Mutations in Adult Chinese Acute Lymphoblastic Leukemia Patients

Role of Signal Transducing Adaptor Protein-1 (STAP-1) in Chronic Myelogenous Leukemia Stem Cells

Signal Transducing Adaptor Protein (STAP) Family Accelerates Gut and Thymic Graft-Versus-Host-Disease in Murine Model

Preclinical Activity of IRAK4 Kinase Inhibitor CA-4948 Alone or in Combination with Targeted Therapies and Preliminary Phase 1 Clinical Results in Non-Hodgkin Lymphoma

Domain-Focused CRISPR-Cas9 Screen Identifies the E3 Ubiquitin Ligase Substrate Adaptor Protein SPOP as a Novel Repressor of Fetal Hemoglobin

Targeting IRAK4 Disrupts Inflammatory Pathways and Delays Tumor Development in Chronic Lymphocytic Leukemia

Target of Erythropoietin, Fam210b , Regulates Erythroid Heme Synthesis By Control of Mitochondrial Iron Import and Regulation of Fech Activity

Lnk/Sh2b3 Deficiency Restores Hematopoietic Stem Cell Function and Genome Integrity in Fanconi Anemia

Unique Roles for Grb2-Associated Binding (Gab) Adaptors in Hematopoietic Stem Cell Homeostasis and Repopulation

Signal-Transducing Adaptor Protein-2 Blocks B Cell Recovery Under Hematological Stress at Pre-B Stage Via TLR4 Signaling

Canonical Inflammasome Formation in Monocytes of Sickle Cell Anemia Patients

The NLRP3 Inflammasome in Platelets Is Upregulated in Sickle Cell Disease and Promotes Platelet Aggregation and In Vitro Thrombosis

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American Society of Hematology

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ASH Publications

American Society of Hematology

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