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Journal Articles

Identification of MALT1 feedback mechanisms enables rational design of potent antilymphoma regimens for ABC-DLBCL

Lorena Fontan, Rebecca Goldstein, Gabriella Casalena, Matthew Durant, Matthew R. Teater, Jimmy Wilson, Jude Phillip, Min Xia, Shivem Shah, Ilkay Us, Himaly Shinglot, Ankur Singh, Giorgio Inghirami, Ari Melnick
Journal: Blood
Blood (2021) 137 (6): 788–800.
https://doi.org/10.1182/blood.2019004713
Published: 2021
Includes: Supplemental data
Journal Articles

LUBAC accelerates B-cell lymphomagenesis by conferring resistance to genotoxic stress on B cells

Tomoyasu Jo, Momoko Nishikori, Yasunori Kogure, Hiroshi Arima, Katsuhiro Sasaki, Yoshiteru Sasaki, Tomoko Nakagawa, Fumie Iwai, Shuji Momose, Aki Shiraishi, Hiroshi Kiyonari, Noritaka Kagaya, Tetsuo Onuki, Kazuo Shin-ya, Minoru Yoshida, Keisuke Kataoka, Seishi Ogawa, Kazuhiro Iwai, Akifumi Takaori-Kondo
Journal: Blood
Blood (2020) 136 (6): 684–697.
https://doi.org/10.1182/blood.2019002654
Published: 2020
Includes: Supplemental data
Journal Articles

A role for NFAT signaling in ABC-DLBCL

Jagan R. Muppidi
Journal: Blood
Blood (2020) 135 (2): 81.
https://doi.org/10.1182/blood.2019004199
Published: 2020
Journal Articles

Treatment Patterns and Outcomes in Patients with Relapsed or Refractory Diffuse Large B-Cell Lymphoma: Experience from a Single UK Centre

John Radford, Ellie White, Felipe A. Castro, PhD, Anshuman Chaturvedi, FRCPath, Nathalie Spielewoy, PhD, Adam Gibb, MBBS, Andy Surinach, MPH, Kim Linton, PhD, Aijing Shang, MD PhD, Michael Wenger, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2917.
https://doi.org/10.1182/blood-2019-123664
Published: 2019
Journal Articles

The Dual Cell Cycle Kinase Inhibitor JNJ-7706621 Reverses Resistance to CD37 Targeted Radioimmunotherapy in Activated B Cell like Diffuse Large B Cell Lymphoma Cell Lines

Gro Elise Rødland, PhD, Katrine Melhus, Roman Generalov, Sania Gilani, Francesco Bertoni, MD, Jostein Dahle, PhD, Randi Syljuåsen, PhD, Sebastian Patzke, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2574.
https://doi.org/10.1182/blood-2019-123287
Published: 2019
Journal Articles

Phased Variant Enrichment for Enhanced Minimal Residual Disease Detection from Cell-Free DNA

David M. Kurtz, MD PhD, Joanne Soo, MD, Stefan Alig, MD, Lyron Co Ting Keh, Charles Macaulay, Michael C. Jin, BS, Florian Scherer, MD, Emily G. Hamilton, BS, Chih Long Liu, PhD, Binbin Chen, PhD, Alexander F. M. Craig, MPhil, Maximilian Diehn, MD PhD, Ash A. Alizadeh, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 552.
https://doi.org/10.1182/blood-2019-131267
Published: 2019
Journal Articles

Paics Inhibition Is a Potential Therapeutic Strategy for MYC-Positive DLBCL

Kohta Miyawaki, MD PhD, Takuji Yamauchi, MD PhD, Takeshi Sugio, MD PhD, Kensuke Sasaki, MD, Hiroaki Miyoshi, MD PhD, Simon Osborne, PhD, Deborah Taylor, PhD, Koichi Ohshima, MD PhD, Koji Kato, MD PhD, Takahiro Maeda, MD PhD, Koichi Akashi, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 396.
https://doi.org/10.1182/blood-2019-129613
Published: 2019
Journal Articles

Interactome of Aiolos/Ikaros in Diffuse Large B-Cell Lymphoma (DLBCL) Reveals Novel Combination of Cereblon Modulators (CELMoD) and Histone Deacetylase (HDAC) Inhibitors

Patrick R. Hagner, PhD, Hsiling Chiu, MS, Vivek S. Chopra, PhD, Martino S. Colombo, PhD, Nisha Patel, PhD, Maria Ortiz, Remco S. Loos, PhD, Fadi Towfic, PhD, Michelle Waldman, MS, Anita K Gandhi
Journal: Blood
Blood (2019) 134 (Supplement_1): 306.
https://doi.org/10.1182/blood-2019-126681
Published: 2019
Journal Articles

Potential Factors That Impact Lenalidomide/R-CHOP Efficacy in Previously Untreated Diffuse Large B-Cell Lymphoma in the ROBUST and ECOG-ACRIN 1412 Studies

Grzegorz Nowakowski, MD, Annalisa Chiappella, Fangxin Hong, PhD, Randy D. Gascoyne, MD, David W. Scott, MBChB, PhD, William R. Macon, MD, Rebecca L. King, MD, Jennifer E. Amengual, MD, Richard F. Little, MD MPH, John P. Leonard, MD, Jonathan W. Friedberg, MD, Lale Kostakoglu, MD MPH, Wojciech Jurczak, Kazuhito Yamamoto, Myron Czuczman, Jacqueline Russo, Krista Hudak, PharmD, Jingshan Zhang, PhD, Steve Wade, Thomas E. Witzig, MD, Brad S. Kahl, MD, Umberto Vitolo
Journal: Blood
Blood (2019) 134 (Supplement_1): 4092.
https://doi.org/10.1182/blood-2019-123083
Published: 2019
Journal Articles

Targeted Protein Degradation of BTK As a Unique Therapeutic Approach for B Cell Malignancies

Aileen Kelly, PhD, Daniel W Robbins, May Tan, Austin Tenn-McClellan, Joel McIntosh, Jeffrey Wu, Zef Konst, Daisuke Kato, Luz Perez, Jennifer Tung, Anna Kolobova, Timothy Ingallinera, Jenny McKinnell, Dahlia Weiss, Mark Noviski, Jordan Ye, Ge Peng, Mario Cardozo, Jeff Mihalic, Steve Basham, Ryan Rountree, Dane E Karr, Neil Bence, Christoph W Zapf, Arthur T Sands
Journal: Blood
Blood (2019) 134 (Supplement_1): 3805.
https://doi.org/10.1182/blood-2019-129262
Published: 2019
Journal Articles

Mutated MYD88 Regulates HCK Pro-Survival Signaling through JunB in MYD88 Mutated B-Lymphoma Cells

Xia Liu, MD, Jiaji G Chen, Manit Munshi, MS, Lian Xu, MS, Amanda Kofides, Nicholas Tsakmaklis, Maria Demos, Maria Luisa Guerrera, MD, Gloria G Chan, MS, Cristina Jimenez, PhD, Zachary R Hunter, PhD, Christopher Patterson, Kirsten Meid, MPH, Andrew Keezer, BS, Jorge J. Castillo, MD, Steven P Treon, MD PhD FRCP, Guang Yang, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3778.
https://doi.org/10.1182/blood-2019-130885
Published: 2019
Journal Articles

Quantitative Proteomics in Diffuse Large B-Cell Lymphoma Patients Reveal Novel Overexpressed Proteins and Potentially Druggable Targets in the ABC Subtype

Susanne Bram Ednersson, MD, Mimmie Stern, MD, Henrik Fagman, Gunilla Enblad, Ulf-Henrik Mellqvist, MD PhD, Herman Nilsson-Ehle, MD PhD, Sverker Hasselblom, Per-Ola Andersson, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3967.
https://doi.org/10.1182/blood-2019-126387
Published: 2019
Journal Articles

BTK Inhibitors Induce ABC-DLBCL Cell Apoptosis By Inhibiting CYLD Phosphorylation

Xin Xu
Journal: Blood
Blood (2019) 134 (Supplement_1): 5046.
https://doi.org/10.1182/blood-2019-126763
Published: 2019
Journal Articles

Curcumin Enhances the Sensitivity of Bortezomib By Inhibiting NF-Κb in ABC Diffuse Large B-Cell Lymphoma Cells

Xiaolei Wei, PhD, Jialin Song, Yongqiang Wei, PhD, Hong Zeng, Weimin Huang, PhD, Jingxia Zheng, Ru Feng, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5237.
https://doi.org/10.1182/blood-2019-127705
Published: 2019
Journal Articles

Phase 1 Dose-Finding Study Investigating CA-4948, an IRAK4 Kinase Inhibitor, in Patients with R/R NHL: Report of Initial Efficacy and Updated Safety Information

Anas Younes, MD, Grzegorz Nowakowski, MD, Allison C. Rosenthal, DO, Lori A. Leslie, MD, Han W. Tun, MD, Matthew A. Lunning, DO, FACP, Iris Isufi, MD, Robert Martell, MD PhD, Krish Patel, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5327.
https://doi.org/10.1182/blood-2019-131851
Published: 2019
Journal Articles

Transformation from Indolent Primary Cutaneous Marginal Zone Lymphoma to Aggressive Primary Cutaneous Diffuse Large B-Cell Lymphoma: A Rare Case and Review of the Literature

Emily Harris, Ariel Sindel, DO, Ian McConnell, William Clark, MDMS, Alden Chesney, MD, Victor Yazbeck, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5266.
https://doi.org/10.1182/blood-2019-130921
Published: 2019
Journal Articles

Subtyping Diffuse Large B-Cell Lymphoma with Cell-of-Origin Using 32-Gene Expression Assay in Formalin-Fixed Paraffin-Embedded Tissue

Xiangnan Jiang, MD, Wanhui Yan, Yifeng Sun, Qinghua Xu, Xiaoyan Zhou, MD, Junning Cao, Xiaonan Hong, Xiaoqiu Li
Journal: Blood
Blood (2019) 134 (Supplement_1): 5337.
https://doi.org/10.1182/blood-2019-126629
Published: 2019
Journal Articles

Quantitative Investigation of Pharmacologically Modulated Signaling and Efficacy in ABC DLBCL Using a Systems Pharmacology Model

Kosinsky Yuri, PhD, Lulu Chu, PhD, Millie Shah, PhD, Karthick Vishwanathan, PhD, Connie Larsson, PhD, Andrew Bloecher, PhD, Brandon Willis, PhD, Hannah Dry, BSc, Kirill Peskov, PhD, Joseph Ware, PhD, Andrew Mortlock, PhD, Gabriel Helmlinger, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5304.
https://doi.org/10.1182/blood-2019-130879
Published: 2019
Journal Articles

MYC and BCL2 mRNA Expression As Determined By NGS Predicts Survival in DLBCL in GCB but Not in ABC Subgroup

Maher Albitar, MD, Xu‐Monette Y Zijun, PhD, Yingjun Wang, Deng Manman, MD, Alexandar Tzankov, Carlo Visco, Govind Bhagat, MD, Karen Dybkær, PhD, Wayne Tam, MD PhD, Eric D. Hsi, MD, Maurilio Ponzoni, MD, Andres JM Ferreri, MD, Michael Boe Møller, Miguel A. Piris, PhD MD, Han van Krieken, MD, Ivan De Dios, BS, Youli Zu, MD PhD, Jane N Winter, MD, Hagop M. Kantarjian, MD, Yong Li, PhD, Ken H. Young
Journal: Blood
Blood (2019) 134 (Supplement_1): 5092.
https://doi.org/10.1182/blood-2019-128492
Published: 2019
Journal Articles

Differences in the Clinicopathological Feature, Prognostic Features and Treatment Outcomes between Molecular Subtypes Among Indian Cohort with Diffuse Large B-Cell Lymphoma - a Single Center Experience

Ashok K Vaid, MDDM, Suman S Karanth, MD DNB, Aseem Khurana, MBBS ,M.Ed, Nitin Sood, MDFRCPath,MRCP, Ashok Sen, MD, Gautam Dheeraj, MD, Bhuvan Chugh, DNB, Saurabh Mishra, MD DNB
Journal: Blood
Blood (2019) 134 (Supplement_1): 5350.
https://doi.org/10.1182/blood-2019-126414
Published: 2019