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Journal Articles

HDAC8 Promotes MLL-Rearranged Acute Myeloid Leukemia By Inhibiting p53 Acetylation

Dijiong Wu, MD, Man Li, PhD, Lianjun Zhang, PhD, Jing Qi, PhD, Chun-Wei David Chen, PhD, Xin He, PhD, Yinghui Zhu, PhD, Haojie Dong, PhD, Jie Sun, PhD, Ling Li, PhD, Guido Marcucci, MD, Ya-Huei Kuo, PhD

Blood (2019) 134 (Supplement_1): 642.

https://doi.org/10.1182/blood-2019-124134

Published: 2019

Journal Articles

A Gain of Function Mutation in the NSD2 Histone Methyltransferase Drives Glucocorticoid Resistance Via Blocking Receptor Auto-Induction and BIM/Bmf Expression in ALL

Blood (2019) 134 (Supplement_1): 3758.

https://doi.org/10.1182/blood-2019-126910

Published: 2019

Journal Articles

Nascent Transcript and Single Cell Rnaseq Analysis Defines the Mechanism of Action of the LSD1 Inhibitor INCB059872 in Myeloid Leukemia

Gretchen Johnston, Haley E. Ramsey, PhDMSc, Kristy Stengel, PhD, Shilpa Sampathi, PhD, Pankaj Acharya, PhD, Maria Arrate, MSc, Matthew C. Stubbs, PhD, Timothy Burn, PhD, Scott Hiebert, PhD, Michael R. Savona, MD

Blood (2019) 134 (Supplement_1): 2509.

https://doi.org/10.1182/blood-2019-130458

Published: 2019

Journal Articles

Fli-1 Transcriptionally Integrates Microenvironmental Cues Sensing By Self-Renewing Hematopoietic Stem and Progenitor Cells

Tomer Itkin, PhD, Chaitanya R Badwe, PhD, Sean Houghton, MSc, Yang Lin, PhD, Ying Liu, PhD, Peipei Guo, PhD, Jesus M Gomez-Salinero, PhD, Fuqiang Geng, PhD, Jae-Hung Shieh, PhD, David Redmond, PhD, Yen-Michael S. Hsu, MD PhD, Brandon Hadland, MD PhD, Shahin Rafii, MD

Blood (2019) 134 (Supplement_1): 725.

https://doi.org/10.1182/blood-2019-126190

Published: 2019

Journal Articles

Innate Immune Signaling Suppresses Acute Leukemia By Modifying MYC Oncogenic Activity

Tomoya Muto, MD PhD, Maria Guillamot, PhD, Jing Fang, MD PhD, Luna Zea Redondo, MS, Kwangmin Choi, PhD, Yixiao Gong, MSc, Callum S Walker, MSc, Kathleen Hueneman, Lyndsey C Bolanos, BSc, Laura Barreyro, PhD, Lynn Lee, MD, Kenneth D Greis, PhD, Alireza Khodadadi-Jamayran, M.Sc., Amaia Lujambio, PhD, Scott W. Lowe, PhD, Iannis Aifantis, PhD, Daniel T. Starczynowski, PhD

Blood (2019) 134 (Supplement_1): 727.

https://doi.org/10.1182/blood-2019-121423

Published: 2019

Journal Articles

Modulation of TET2 Activity By Ascorbic Acid and Factors Affecting Lysine Acetylation

Blood (2018) 132 (Supplement 1): 4346.

https://doi.org/10.1182/blood-2018-99-119712

Published: 2018

Journal Articles

SIRT1 Mediates Enhanced Mitochondrial Oxidative Phosphorylation in Chronic Myelogenous Leukemia Stem Cells

Ajay Abraham, PhD, Shaowei Qiu, MD, Balu K Chacko, PhD, Hui Li, BS, Andrew J Paterson, PhD, Jianbo He, MD, Puneet Agarwal, PhD, Mansi Shah, PhD, Robert S. Welner, PhD, Victor M Darley-Usmar, PhD, Ravi Bhatia, MD

Blood (2018) 132 (Supplement 1): 932.

https://doi.org/10.1182/blood-2018-99-115709

Published: 2018

Journal Articles

SIRT3 Sumoylation Contributes to Chemoresistance in AML

Jiao MA, PhD, Bin Liu, MSc, Dan Yu, BSc, Wayne Tam, MD PhD, Jianmin Yang, PhD, Jinke Cheng, PhD

Blood (2018) 132 (Supplement 1): 3929.

https://doi.org/10.1182/blood-2018-99-110898

Published: 2018

Journal Articles

Hematopoietic Stem and Progenitor Cell Proliferation and Differentiation Requires the Trithorax Protein Ash2l In Vivo

Nicolas Chatain, PhD, Juliane Lüscher-Firzlaff, Chao-Chung Kuo, Agnieszka Bochyńska, Andrea Ullius, Bernd Denecke, Ivan Costa, Steffen Koschmieder, MD, Bernhard Lüscher

Blood (2018) 132 (Supplement 1): 2566.

https://doi.org/10.1182/blood-2018-99-115950

Published: 2018

Journal Articles

A Stemness Screen Reveals C3ORF54/INKA1 As a Gate-Keeper of Human Stem Cell Latency

Kerstin B. Kaufmann, PhD, Laura Garcia Prat, Shin-Ichiro Takayanagi, PhD, Jessica McLeod, BSc, Olga I. Gan, Kristele Pan, Stephanie Zhi-Juan Xie, PhD, John E. Dick, PhD

Blood (2018) 132 (Supplement 1): 325.

https://doi.org/10.1182/blood-2018-99-115065

Published: 2018

Journal Articles

Shielding p53 from destruction

Deepa Sampath

Blood (2018) 131 (25): 2740–2741.

https://doi.org/10.1182/blood-2018-04-845800

Published: 2018

Journal Articles

MiR-181a Down-Regulates PARP1 By Enhancing Its Acetylation in MLL -Rearranged AML

Di Zhou, PhD, Jian Ouyang, MD, Bing Chen, MD PhD

Blood (2017) 130 (Supplement 1): 1388.

https://doi.org/10.1182/blood.V130.Suppl_1.1388.1388

Published: 2017

Journal Articles

PRMT5 Regulates DNA Repair By Controlling the Alternative Splicing of Epigenetic Factors

Pierre-Jacques Hamard, PhD, Gabriel Emmanuel Santiago, Fan Liu, PhD, Sarah Greenblatt, PhD, Daniel Karl, PhD, Concepcion Martinez, B.S., Ramiro E Verdun, PhD, Stephen D. Nimer, MD

Blood (2017) 130 (Supplement 1): 1148.

https://doi.org/10.1182/blood.V130.Suppl_1.1148.1148

Published: 2017

Journal Articles

The Therapeutic Response of Chidamide Was Associated with Elevated H3 Acetylation Level in Patients with Refractory/Relapsed Non-Hodgkin Lymphoma (R/R-NHL)

Hui-qiang Huang, MD PhD, Pengfei Li, Yan Gao, Bai Bing, Wang Xiaoxiao, Rong Qixiang, Su Li, Wenqi Jiang

Blood (2017) 130 (Supplement 1): 4080.

https://doi.org/10.1182/blood.V130.Suppl_1.4080.4080

Published: 2017

Journal Articles

H3K27M/I Mutations Promote Context-Dependent Transformation in Acute Myeloid Leukemia with RUNX1 Alterations

Bernhard Lehnertz, PhD, Yu Wei Zhang, Isabel Boivin, Nadine Mayotte, Tomellini Elisa, PhD, Jalila Chagraoui, PhD, Vincent-Philippe Lavallée, MD, Josée Hébert, MD, Guy Sauvageau, MD, PhD

Blood (2017) 130 (Supplement 1): 302.

https://doi.org/10.1182/blood.V130.Suppl_1.302.302

Published: 2017

Journal Articles

Identification of Acetylation, Immune Cell Alterations and Gene Signature As Dynamic Biomarkers of Response to Panobinostat Treatment in Multiple Myeloma Patients

Sridurga Mithraprabhu, PhD MSc, Ioanna Savvidou, MD, Malarmathy Ramachandran, Anna Kalff, MBBS, Tiffany T. Khong, BSc,PhD, Kate Reed, John Reynolds, PhD, Andrew Spencer, MD

Blood (2017) 130 (Supplement 1): 1823.

https://doi.org/10.1182/blood.V130.Suppl_1.1823.1823

Published: 2017

Journal Articles

Molecular Insights at the Single Cell Level into the Reprogramming of Human Hematopoietic Stem Cells during Epigenetically Modified Ex Vivo Expansion

Peng Hua, PhD, Barbara Kronsteiner, PhD, Neil Ashley, PhD, Mark van der Garde, PhD, Diana Hernandez, PhD, Marina Tarunina, PhD, Lilian Hook, PhD, Yen Choo, PhD, Irene Roberts, MD, Adam J Mead, MD PhD, Suzanne M Watt, PhDFRCPath

Blood (2017) 130 (Supplement 1): 2425.

https://doi.org/10.1182/blood.V130.Suppl_1.2425.2425

Published: 2017

Journal Articles

Controlling Hematopoietic Stem Cell Quiescence By Ablating the TGFβ-Responsive, Hematopoietic-Hpecific Enhancer of CDKN1C (p57)

Mia Yabut, BS, Fabienne Brenet, PhD, Nassima Messali, PhD, Nicole Molle, BS, Pouneh Kermani, PhD, Silvana Di Giandomenico, PhD, Matthew Brown, BS, Joseph Scandura, MDPhD

Blood (2017) 130 (Supplement 1): 2436.

https://doi.org/10.1182/blood.V130.Suppl_1.2436.2436

Published: 2017

Journal Articles

GFI1b As a Novel Oncosuppressor in AML

Aniththa Thivakaran, M.Sc., Lacramioara Botezatu, PhD, Judith Maria Hoenes, M.Sc., Yahya Saleh Al-Matary, MSc, Nadine Olberding, B.Sc, Judith Schütte, PhD, Renata Köster, Bertram Opalka, PhD, Ulrich Dührsen, MD, Cyrus Khandanpour, MD

Blood (2016) 128 (22): 2717.

https://doi.org/10.1182/blood.V128.22.2717.2717

Published: 2016

Journal Articles

Dual Inhibition of Histone Deacetylases and Phosphoinositide 3-Kinase Enhances Therapeutic Activity Against B Cell Lymphoma

Patrizia Mondello, MD MSc, Enrico Derenzini, MD, Zahra Asgari, John Philip, Elliot J Brea, PhD, Venkatraman E Seshan, PhD, Ronald Hendrickson, PhD, Elisa de Stanchina, PhD, David A Scheinberg, MD PhD, Anas Younes, MD

Blood (2016) 128 (22): 293.

https://doi.org/10.1182/blood.V128.22.293.293

Published: 2016

NARROW

HDAC8 Promotes MLL-Rearranged Acute Myeloid Leukemia By Inhibiting p53 Acetylation

A Gain of Function Mutation in the NSD2 Histone Methyltransferase Drives Glucocorticoid Resistance Via Blocking Receptor Auto-Induction and BIM/Bmf Expression in ALL

Nascent Transcript and Single Cell Rnaseq Analysis Defines the Mechanism of Action of the LSD1 Inhibitor INCB059872 in Myeloid Leukemia

Fli-1 Transcriptionally Integrates Microenvironmental Cues Sensing By Self-Renewing Hematopoietic Stem and Progenitor Cells

Innate Immune Signaling Suppresses Acute Leukemia By Modifying MYC Oncogenic Activity

Modulation of TET2 Activity By Ascorbic Acid and Factors Affecting Lysine Acetylation

SIRT1 Mediates Enhanced Mitochondrial Oxidative Phosphorylation in Chronic Myelogenous Leukemia Stem Cells

SIRT3 Sumoylation Contributes to Chemoresistance in AML

Hematopoietic Stem and Progenitor Cell Proliferation and Differentiation Requires the Trithorax Protein Ash2l In Vivo

A Stemness Screen Reveals C3ORF54/INKA1 As a Gate-Keeper of Human Stem Cell Latency

Shielding p53 from destruction

MiR-181a Down-Regulates PARP1 By Enhancing Its Acetylation in MLL -Rearranged AML

PRMT5 Regulates DNA Repair By Controlling the Alternative Splicing of Epigenetic Factors

The Therapeutic Response of Chidamide Was Associated with Elevated H3 Acetylation Level in Patients with Refractory/Relapsed Non-Hodgkin Lymphoma (R/R-NHL)

H3K27M/I Mutations Promote Context-Dependent Transformation in Acute Myeloid Leukemia with RUNX1 Alterations

Identification of Acetylation, Immune Cell Alterations and Gene Signature As Dynamic Biomarkers of Response to Panobinostat Treatment in Multiple Myeloma Patients

Molecular Insights at the Single Cell Level into the Reprogramming of Human Hematopoietic Stem Cells during Epigenetically Modified Ex Vivo Expansion

Controlling Hematopoietic Stem Cell Quiescence By Ablating the TGFβ-Responsive, Hematopoietic-Hpecific Enhancer of CDKN1C (p57)

GFI1b As a Novel Oncosuppressor in AML

Dual Inhibition of Histone Deacetylases and Phosphoinositide 3-Kinase Enhances Therapeutic Activity Against B Cell Lymphoma

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American Society of Hematology

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ASH Publications

American Society of Hematology

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