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Yuan-I Chang
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Journal Articles

Canonical Notch Signaling Is Required for Kras G12D -Induced Myeloproliferative Neoplasm

Xiaona You, PhD, Guangyao Kong, Zhi Wen, Yuan-I Chang, Erik A. Ranheim, MD PhD, Eric Padron, MD, Jing Zhang, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1220.
https://doi.org/10.1182/blood.V130.Suppl_1.1220.1220
Published: 2017
Journal Articles

p53 −/− synergizes with enhanced Nras G12D signaling to transform megakaryocyte-erythroid progenitors in acute myeloid leukemia

Jingfang Zhang, Guangyao Kong, Adhithi Rajagopalan, Li Lu, Jingming Song, Mohamed Hussaini, Xinmin Zhang, Erik A. Ranheim, Yangang Liu, Jinyong Wang, Xin Gao, Yuan-I Chang, Kirby D. Johnson, Yun Zhou, David Yang, Bhavana Bhatnagar, David M. Lucas, Emery H. Bresnick, Xuehua Zhong, Eric Padron, Jing Zhang
Journal: Blood
Blood (2017) 129 (3): 358–370.
https://doi.org/10.1182/blood-2016-06-719237
Published: 2017
Includes: Supplemental data
Journal Articles

Downregulating Notch Counteracts Kras G12D -Induced ERK Activation and Oxidative Phosphorylation in Myeloproliferative Neoplasm

Guangyao Kong, PhD, Yuan-I Chang, PhD, Jingfang Zhang, PhD, Erik A. Ranheim, MD, Xinmin Zhang, Yun Zhou, Yangang Liu, Lan Zhou, MD PhD, Warren S. Pear, MD PhD, Jing Zhang, PhD
Journal: Blood
Blood (2016) 128 (22): 1565.
https://doi.org/10.1182/blood.V128.22.1565.1565
Published: 2016
Journal Articles

Dnmt3a Haploisufficiency Cooperates with Oncogenic Kras to Promote an Early-Onset T-Cell Leukemia

Yuan-I Chang, PhD, Guangyao Kong, PhD, Jing Zhang, PhD, Erik A. Ranheim, MD
Journal: Blood
Blood (2016) 128 (22): 2729.
https://doi.org/10.1182/blood.V128.22.2729.2729
Published: 2016
Journal Articles

Downregulating Notch Signaling in Kras G12D/+ Mice Inhibits Both T-Cell Leukemia and Myeloproliferative Neoplasm in a Cell-Autonomous Manner

Guangyao Kong, PhD, Yuan-I Chang, PhD, Erik A. Ranheim, MD, Yun Zhou, Yangang Liu, Paul Lambert, PhD, Lan Zhou, MD PhD, Pamela Stanley, PhD, Warren S. Pear, MD PhD, Jing Zhang, PhD
Journal: Blood
Blood (2014) 124 (21): 261.
https://doi.org/10.1182/blood.V124.21.261.261
Published: 2014
Journal Articles

Genetic Basis For Hematopoietic Stem Cell Generation In The Mammalian Embryo

Xin Gao, Kirby D Johnson, PhD, Yuan-I Chang, PhD, Meghan E Boyer, Colin N Dewey, PhD, Jing Zhang, PhD, Emery Bresnick, PhD
Journal: Blood
Blood (2013) 122 (21): 3667.
https://doi.org/10.1182/blood.V122.21.3667.3667
Published: 2013
Journal Articles

Loss Of p53 Promotes Transformation Of Oncogenic Nras-Induced Chronic Myelomonocytic Leukemia To An Acute Phase

Jingfang Zhang, Yangang Liu, Guangyao Kong, PhD, Yuan-I Chang, PhD, Erik A. Ranheim, MD, Jinyong Wang, PhD, Juan Du, PhD, Alisa Damnernsawad, Jing Zhang, PhD
Journal: Blood
Blood (2013) 122 (21): 3790.
https://doi.org/10.1182/blood.V122.21.3790.3790
Published: 2013
Journal Articles

Kras Plays An Important Role In Generating Differentiated Blood Cells

Alisa Damnernsawad, Guangyao Kong, PhD, Yangang Liu, Yuan-I Chang, PhD, Jingfang Zhang, Qiang Chang, Jing Zhang, PhD
Journal: Blood
Blood (2013) 122 (21): 2451.
https://doi.org/10.1182/blood.V122.21.2451.2451
Published: 2013
Journal Articles

Nras G12D/+ promotes leukemogenesis by aberrantly regulating hematopoietic stem cell functions

Brief Report
Jinyong Wang, Guangyao Kong, Yangang Liu, Juan Du, Yuan-I Chang, Sin Ruow Tey, Xinmin Zhang, Erik A. Ranheim, Marc K. Saba-El-Leil, Sylvain Meloche, Alisa Damnernsawad, Jingfang Zhang, Jing Zhang
Journal: Blood
Blood (2013) 121 (26): 5203–5207.
https://doi.org/10.1182/blood-2012-12-475863
Published: 2013
Includes: Supplemental data