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Journal Articles

Preliminary Safety and Efficacy of Bgb-11417, a Novel Bcl-2 Inhibitor, in Combination with Azacitidine in Patients with Acute Myeloid Leukemia (AML)

Jake Shortt, Pau Montesinos, Shuh Ying Tan, Teng Fong Ng, Chun Yew Fong, Paul Cannell, Rajeev Rajagopal, Sophia Leitch, Peter T. Tan, Sundra Ramanathan, Robin Gasiorowski, Douglas Stuart Lenton, Tse-Chieh Teh, José Antonio Pérez-Simón, Carolyn Grove, Xiaojun Huang, Courtney D. DiNardo, Katherine Naidu, Joseph Pariseau, Si Cheng, Yu Liu, Melannie Co, Wai Y. Chan, Haiyi Guo, Andrew H. Wei
Journal: Blood
Blood (2022) 140 (Supplement 1): 3329–3332.
DOI: https://doi.org/10.1182/blood-2022-166937
Published: 2022
Journal Articles

KMT2D Deficiency Promotes Myeloid Leukemias through Regulating Ribosome Biogenesis

Jing Xu, Ailing Zhong, Chong Chen, Yu Liu, Ting Niu
Journal: Blood
Blood (2022) 140 (Supplement 1): 5855–5856.
DOI: https://doi.org/10.1182/blood-2022-168509
Published: 2022
Journal Articles

BMS-986158, a Potent BET Inhibitor, As Monotherapy and in Combination with Ruxolitinib or Fedratinib in Intermediate- or High-Risk Myelofibrosis: First Results from a Phase 1/2 Study

Rosa Ayala, Nieves Lopez, Adi Shacham Abulafia, Maan Alwan, Costas K. Yannakou, Indu Raman, Vincent Ribrag, Chun Yew Fong, Yulia Volchek, Massimiliano Bonifacio, Alessandra Tucci, Jean-Jacques Kiladjian, Henry Chang, Sharmila Das, Bin Wu, Palanikumar Ravindran, Vivian Shan, Guan Wang, Oriana Esposito, Yu Liu, Zariana Nikolova, Christopher Tehlirian, Shodeinde Coker, David Lavie
Journal: Blood
Blood (2022) 140 (Supplement 1): 9665–9667.
DOI: https://doi.org/10.1182/blood-2022-159476
Published: 2022
Journal Articles

A Transcriptional Classifier Identifies Pediatric T-Cell Acute Lymphoblastic Leukemias at High Risk for End of Induction Minimal Residual Disease

Lauren K. Meyer, Ritu P. Roy, Petri Pölönen, Abdelrahman Elsayed, Benjamin J. Huang, Shunsuke Kimura, Cristina Delgado-Martin, Tiffaney L. Vincent, Theresa Ryan, Brent L. Wood, Zhiguo Chen, Yu Liu, Jinghui Zhang, Terzah M. Horton, Mignon L. Loh, Meenakshi Devidas, Elizabeth A. Raetz, Robert J. Hayashi, Stuart S. Winter, Kimberly P. Dunsmore, Stephen P. Hunger, Stanley B. Pounds, Michelle L. Hermiston, Jun J. Yang, Charles G. Mullighan, David T. Teachey, Adam B. Olshen
Journal: Blood
Blood (2022) 140 (Supplement 1): 1722–1723.
DOI: https://doi.org/10.1182/blood-2022-165233
Published: 2022
Journal Articles

CoupledCAR TM Technology for Treating Thyroid Cancer

Xingchen Liu, Lei Xiao, PhD, Keshu Zhou, Yu Liu, Yong Huang, Chengfei Pu, Zhiyuan Cao, Ruihong Zhu, Haiyang Tang, Zhipeng Huang, Hang Yang, Xi Huang, Yongping Song, Renbin Liu, Zhao Wu
Journal: Blood
Blood (2020) 136 (Supplement 1): 46.
DOI: https://doi.org/10.1182/blood-2020-138668
Published: 2020
Journal Articles

Distinct Genomic Landscape of Chinese Pediatric Acute Myeloid Leukemia

Ting Liu, MD, Jianan Rao, Master, Wenting Hu, MD, Yuhan Liu, MD, Huiying Sun, Master, Xiaoxiao Chen, MD, Yanjing Tang, MDPhD, Jing Chen, MD, Xiang Wang, PhD, Han Wang, Master, Wubin Qian, PhD, Binchen Mao, PhD, Sheng Guo, PhD, Ronghua Wang, Master, Yu Liu, PhD, Shuhong Shen, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 38.
DOI: https://doi.org/10.1182/blood-2020-140150
Published: 2020
Journal Articles

Nivolumab treatment of relapsed/refractory Epstein-Barr virus–associated hemophagocytic lymphohistiocytosis in adults

Clinical Trials & Observations
Pengpeng Liu, Xiangyu Pan, Chong Chen, Ting Niu, Xiao Shuai, Jian Wang, Xuelan Chen, Jiazhuo Liu, Yong Guo, Liping Xie, Yu Wu, Yu Liu, Ting Liu
Journal: Blood
Blood (2020) 135 (11): 826–833.
DOI: https://doi.org/10.1182/blood.2019003886
Published: 2020
Includes: Supplemental data
Journal Articles

Therapy-induced mutations drive the genomic landscape of relapsed acute lymphoblastic leukemia

Benshang Li, Samuel W. Brady, Xiaotu Ma, Shuhong Shen, Yingchi Zhang, Yongjin Li, Karol Szlachta, Li Dong, Yu Liu, Fan Yang, Ningling Wang, Diane A. Flasch, Matthew A. Myers, Heather L. Mulder, Lixia Ding, Yanling Liu, Liqing Tian, Kohei Hagiwara, Ke Xu, Xin Zhou, Edgar Sioson, Tianyi Wang, Liu Yang, Jie Zhao, Hui Zhang, Ying Shao, Hongye Sun, Lele Sun, Jiaoyang Cai, Hui-Ying Sun, Ting-Nien Lin, Lijuan Du, Hui Li, Michael Rusch, Michael N. Edmonson, John Easton, Xiaofan Zhu, Jingliao Zhang, Cheng Cheng, Benjamin J. Raphael, Jingyan Tang, James R. Downing, Ludmil B. Alexandrov, Bin-Bing S. Zhou, Ching-Hon Pui, Jun J. Yang, Jinghui Zhang
Journal: Blood
Blood (2020) 135 (1): 41–55.
DOI: https://doi.org/10.1182/blood.2019002220
Published: 2020
Includes: Supplemental data
Journal Articles

Integrative Analysis of Pediatric Acute Leukemia Identifies Immature Subtypes That Span a T Lineage and Myeloid Continuum with Distinct Prognoses

Tanja A. Gruber, MD PhD, Jing Ma, PhD, Sanne Noort, MD MSc, Yu Liu, PhD, Michael P Walsh, PhD, Stephanie Nance, PhD, Yanling Liu, PhD, Yuanyuan Wang, PhD, Guangchun Song, PhD, Tamara Lamprecht, BS, John Easton, PhD, Martina Pigazzi, PhD, Marie Jarosova, PhD, Kelaidi Charikleia, MD, Jeffrey Rubnitz, MD PhD, Dirk Reinhardt, MD, Marry M. van den Heuvel-Eibrink, Prof, MD PhD, Franco Locatelli, MD PhD, Henrik Hasle, Jeffery M. Klco, MD PhD, James R. Downing, MD, Stanley Pounds, PhD, Jinghui Zhang, PhD, Christian Michel Zwaan, MD PhD, Maarten Fornerod, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 918.
DOI: https://doi.org/10.1182/blood-2019-127411
Published: 2019
Journal Articles

Stag2 Regulates Hematopoietic Differentiation and Self-Renewal through Alterations in Gene Expression and Topological Control

Aaron D Viny, MDMS, Robert L Bowman, PhD, Yu Liu, PhD, Vincent-Philippe Lavallee, MD, Shira Eisman, Wenbin Xiao, MD PhD, Benjamin H Durham, MD, Anastasia Navitski, Jane Park, Stephanie Braunstein, Besmira Alija, Abdul Karzai, Isabelle S. Csete, Matthew Witkin, Elham Azizi, PhD, Timour Baslan, Christopher J. Ott, PhD, Dana Pe'er, PhD, Job Dekker, Richard Koche, PhD, Ross L. Levine, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 279.
DOI: https://doi.org/10.1182/blood-2019-123464
Published: 2019
Journal Articles

The Genomic Landscape of Childhood Acute Lymphoblastic Leukemia

Kathryn G. Roberts, PhD, Samuel W. Brady, PhD, Zhaohui Gu, PhD, Lei Shi, PhD, Stanley Pounds, PhD, Deqing Pei, MS, Cheng Cheng, PhD, Yunfeng Dai, PhD, Meenakshi Devidas, PhD, Chunxu Qu, PhD, Ashley Hill, BS, Xiaotu Ma, Lei Wei, PhD, Sasi Arunachalam, PhD, Kohei Hagiwara, MD, Yangling Liu, Diane Flasch, Yu Liu, PhD, Matthew Parker, PhD, Xiaolong Chen, PhD, Yongjin Li, PhD, Yiping Fan, PhD, Robert Michael, PhD, Michael Rusch, BS, Mark Wilkinson, Scott Foy, PhD, Dale Hedges, PhD, Scott Newman, PhD, Xin Zhou, PhD, Jian Wang, Shalini C. Reshmi, PhD, Julie M. Gastier-Foster, PhD, Patee Gesuwan, Malcolm A Smith, MD PhD, Daniela S. Gerhard, PhD, Naomi Winick, MD, Andrew J. Carroll, PhD, Nyla A. Heerema, PhD, Richard C. Harvey, PhD, Cheryl L. Willman, MD, Eric Larsen, MD, Elizabeth A. Raetz, MD, Michael J. Borowitz, MD PhD, Brent L Wood, MD PhD, William L. Carroll, MD, Patrick A. Zweidler-McKay, MD PhD, Karen R. Rabin, MD PhD, Leonard A. Mattano, MD, Kelly Maloney, MD, Stuart S. Winter, MD, Michael J. Burke, MD, Wanda L. Salzer, MD, Kimberly P. Dunsmore, Anne Angiolillo, MD, Kristine R Crews, PharmD, James R. Downing, MD, Sima Jeha, MD, William E. Evans, PharmD, Ching-Hon Pui, MD, Jun J. Yang, PhD, Mary V. Relling, PharmD, Stephen P. Hunger, MD, Mignon L. Loh, MD, Jinghui Zhang, PhD, Charles G. Mullighan, MBBS, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 649.
DOI: https://doi.org/10.1182/blood-2019-124881
Published: 2019
Journal Articles

KMT2D Is a Haploinsufficient Tumor Suppressor in Acute Leukemia

Jing Xu, MD, Yu Liu, PhD, Chong Chen, PhD, Ting Niu, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1511.
DOI: https://doi.org/10.1182/blood-2018-99-119038
Published: 2018
Journal Articles

Mutational Landscape and Temporal Evolution during Treatment of Relapsed Acute Lymphoblastic Leukemia

Benshang Li, Yongjin Li, PhD, Shuhong Shen, MD PhD, Yingchi Zhang, Samuel Brady, PhD, Xiaotu Ma, Yu Liu, PhD, Ningling Wang, Diane Flasch, Matthew Myers, Heather Mulder, BS, Yanling Liu, Liqing Tian, Kohei Hagiwara, MD, Hui Zhang, Ying Shao, Hongye Sun, Lele Sun, Ting-Nien Lin, Lijuan Du, Fan Yang, Michael Rusch, BS, Michael Edmonson, John Easton, PhD, Xiaofan Zhu, PhD, Jingliao Zhang, MD, Cheng Cheng, PhD, Benjamin Raphael, Jing-Yan Tang, James R. Downing, MD, Bin-Bing Zhou, Ching-Hon Pui, MD, Jun J. Yang, PhD, Jinghui Zhang
Journal: Blood
Blood (2018) 132 (Supplement 1): 917.
DOI: https://doi.org/10.1182/blood-2018-99-119144
Published: 2018
Journal Articles

Alox15b Gene Contributes to Lymphoma Tumorigenesis Via PI3K/AKT/mTOR Pathway Activation and Has a Synergistic Effect with Alox5 Gene

Pengpeng Liu, MD, Yu Liu, PhD, Chong Chen, PhD, Ting Liu, MD, Ting Niu, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4112.
DOI: https://doi.org/10.1182/blood-2018-99-120130
Published: 2018
Journal Articles

Genomic and Outcome Analyses of Philadelphia Chromosome-like (Ph-like) NCI Standard Risk B-Acute Lymphoblastic Leukemia (SR B-ALL) Patients Treated on Children's Oncology Group (COG) AALL0331

Shalini C. Reshmi, PhD, Richard C. Harvey, PhD, Kathryn G. Roberts, PhD, Eileen Stonerock, BS, ASCP(MB), Yunfeng Dai, PhD, I-Ming L. Chen, DVM, MS, Marc Valentine, BA, Yu Liu, PhD, Yongjin Li, PhD, Jinghui Zhang, PhD, Debbie Payne-Turner, BS, Meenakshi Devidas, PhD, Nyla A. Heerema, PhD, Andrew Carroll, PhD, Elizabeth A. Raetz, MD, Michael Borowitz, MD PhD, Brent Wood, MDPhD, Anne Angiolillo, MD, Michael J. Burke, MD, Wanda Salzer, MD, Patrick A. Zweidler-McKay, MDPhD, Karen R. Rabin, MD PhD, Leonard A. Mattano, MD, Kelly Maloney, MD, William L. Carroll, MD, Mignon L. Loh, MD, Charles G. Mullighan, MBBS, MD, Cheryl L. Willman, MD, Julie M. Gastier-Foster, PhD, Stephen P. Hunger, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 477.
DOI: https://doi.org/10.1182/blood.V130.Suppl_1.477.477
Published: 2017
Journal Articles

Targetable kinase gene fusions in high-risk B-ALL: a study from the Children’s Oncology Group

Shalini C. Reshmi, Richard C. Harvey, Kathryn G. Roberts, Eileen Stonerock, Amy Smith, Heather Jenkins, I-Ming Chen, Marc Valentine, Yu Liu, Yongjin Li, Ying Shao, John Easton, Debbie Payne-Turner, Zhaohui Gu, Thai Hoa Tran, Jonathan V. Nguyen, Meenakshi Devidas, Yunfeng Dai, Nyla A. Heerema, Andrew J. Carroll, III, Elizabeth A. Raetz, Michael J. Borowitz, Brent L. Wood, Anne L. Angiolillo, Michael J. Burke, Wanda L. Salzer, Patrick A. Zweidler-McKay, Karen R. Rabin, William L. Carroll, Jinghui Zhang, Mignon L. Loh, Charles G. Mullighan, Cheryl L. Willman, Julie M. Gastier-Foster, Stephen P. Hunger
Journal: Blood
Blood (2017) 129 (25): 3352–3361.
DOI: https://doi.org/10.1182/blood-2016-12-758979
Published: 2017
Includes: Supplemental data
Journal Articles

The Genomic Landscape of Childhood T-Lineage Acute Lymphoblastic Leukemia

Yu Liu, PhD, John Easton, PhD, Ying Shao, Mark Wilkinson, Michael Edmonson, PhD, Xiaotu Ma, PhD, Malcolm A. Smith, MD PhD, Michael Rusch, BA, Jaime Guidry Auvil, Daniela S. Gerhard, PhD, Mary V. Relling, PharmD, Naomi J. Winick, MD, Elizabeth Raetz, MD, Meenakshi Devidas, PhD, Cheryl L. Willman, MD, Richard C. Harvey, PhD, William L. Carroll, MD, Kimberly P. Dunsmore, MD, Stuart S. Winter, MD, Brent L Wood, MD PhD, James R. Downing, MD, Mignon L. Loh, MD, Stephen P Hunger, MD, Jinghui Zhang, PhD, Charles G. Mullighan, MBBS, MSc, MD
Journal: Blood
Blood (2015) 126 (23): 691.
DOI: https://doi.org/10.1182/blood.V126.23.691.691
Published: 2015
Journal Articles

Decision-Tree Algorithm Optimize Hematopoietic Progenitor Cell-Based Prediction in Peripheral Blood Stem Cell Mobilization

Chia-Yun Wu, Tzeon-Jye Chiou, MD, Chun-Yu Liu, Feng-Chang Lin, Jeong-Shi Lin, Man-Hsin Hung, Liang-Tsai Hsiao, Jyh-Pyng Gau, MD, Jin-Hwang Liu, MD PhD, Hsiu-Ju Yen, Giun-Yi Hung, MD, Hui-Chi Hsu, Cheng-Hwai Tzeng, Muh-Hwa Yang, Po-Min Chen, Yuan-Bin Yu
Journal: Blood
Blood (2015) 126 (23): 1903.
DOI: https://doi.org/10.1182/blood.V126.23.1903.1903
Published: 2015
Journal Articles

PARP-14 combines with tristetraprolin in the selective posttranscriptional control of macrophage tissue factor expression

M. Bilal Iqbal, Michael Johns, Jun Cao, Yu Liu, Sheng-Chun Yu, Gareth D. Hyde, Michael A. Laffan, Francesco P. Marchese, Sung Hoon Cho, Andrew R. Clark, Felicity N. Gavins, Kevin J. Woollard, Perry J. Blackshear, Nigel Mackman, Jonathan L. Dean, Mark Boothby, Dorian O. Haskard
Journal: Blood
Blood (2014) 124 (24): 3646–3655.
DOI: https://doi.org/10.1182/blood-2014-07-588046
Published: 2014
Includes: Supplemental data
Journal Articles

Higher bone marrow LGALS3 expression is an independent unfavorable prognostic factor for overall survival in patients with acute myeloid leukemia

Chieh-Lung Cheng, Hsin-An Hou, Ming-Cheng Lee, Chieh-Yu Liu, Jie-Yang Jhuang, Yan-Jun Lai, Chung-Wu Lin, Huan-Yuan Chen, Fu-Tong Liu, Wen-Chien Chou, Chien-Yuan Chen, Jih-Luh Tang, Ming Yao, Shang-Yi Huang, Bor-Sheng Ko, Shang-Ju Wu, Woei Tsay, Hwei-Fang Tien
Journal: Blood
Blood (2013) 121 (16): 3172–3180.
DOI: https://doi.org/10.1182/blood-2012-07-443762
Published: 2013
Includes: Supplemental data