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Journal Articles

Targeting Cancer-Associated Fibroblasts in the Bone Marrow Prevents Resistance to CART-Cell Therapy in Multiple Myeloma

Reona Sakemura, Mehrdad Hefazi, Elizabeth L. Siegler, Michelle J Cox, Daniel P Larson, Michael J. Hansen, Claudia Manriquez Roman, Kendall J. Schick, Ismail Can, Erin E Tapper, Paulina Horvei, Mohamad M. Adada, Evandro D. Bezerra, Lionel Aurelien Kankeu Fonkoua, Michael W Ruff, Wendy Nevala, Denise K Walters, Sameer A Parikh, Yi Lin, Diane F Jelinek, Neil E. Kay, P. Leif Bergsagel, Saad S. Kenderian
Journal: Blood
Blood blood.2021012811.
DOI: https://doi.org/10.1182/blood.2021012811
Published: 2022
Includes: Supplemental data
Journal Articles

Mortality Trends in Multiple Myeloma after the Introduction of Novel Therapies in the United States

Bharat Nandakumar, Moritz Binder, S. Vincent Rajkumar, Prashant Kapoor, Francis K. Buadi, David Dingli, Martha Q. Lacy, Morie A. Gertz, Suzanne R. Hayman, Nelson Leung, Amie Fonder, Miriam A. Hobbs, Yi L. Hwa, Eli Muchtar, Rahma M Warsame, Taxiarchis Kourelis, Wilson I Gonsalves, Stephen J. Russell, Yi Lin, Mustaqeem A. Siddiqui, Robert A. Kyle, Angela Dispenzieri, Shaji Kumar
Journal: Blood
Blood (2021) 138 (Supplement 1): 119.
DOI: https://doi.org/10.1182/blood-2021-146894
Published: 2021
Journal Articles

Response to COVID-19 Vaccination Post-CAR T Therapy in Patients with Non-Hodgkin Lymphoma and Multiple Myeloma

Julia E. Wiedmeier, Madiha Iqbal, Javier Munoz, Evandro D. Bezerra, Juan Esteban Garcia Robledo, Radhika Bansal, Patrick B. Johnston, Matthew Hathcock, Jeremy T. Larsen, P. Leif Bergsagel, Yucai Wang, Craig B. Reeder, Jose F. Leis, Rafael Fonseca, Jeanne M. Palmer, Rahma M Warsame, Taxiarchis Kourelis, Suzanne R. Hayman, David Dingli, Prashant Kapoor, Shaji Kumar, Urshila Durani, Jose C. Villasboas, Jonas Paludo, N. Nora Bennani, Stephen M. Ansell, Januario E Castro, Mohamed A. Kharfan-Dabaja, Yi Lin, Paschalis Vergidis, Hemant S. Murthy, Allison C. Rosenthal
Journal: Blood
Blood (2021) 138 (Supplement 1): 1750.
DOI: https://doi.org/10.1182/blood-2021-151859
Published: 2021
Journal Articles

Long-Term (≥4 Year and ≥5 Year) Overall Survival (OS) By 12- and 24-Month Event-Free Survival (EFS): An Updated Analysis of ZUMA-1, the Pivotal Study of Axicabtagene Ciloleucel (Axi-Cel) in Patients (Pts) with Refractory Large B-Cell Lymphoma (LBCL)

Caron Jacobson, Frederick L. Locke, Armin Ghobadi, David B. Miklos, Lazaros J. Lekakis, Olalekan O. Oluwole, Yi Lin, Brian T. Hill, John M. Timmerman, Abhinav Deol, Patrick M. Reagan, Patrick Stiff, Ian W. Flinn, Umar Farooq, Andre H. Goy, Javier Muñoz, Tanya Siddiqi, Rhine R. Shen, Adrian Bot, Jinghui Dong, Kanwarjit Singh, Clare Spooner, Roshan Karalliyadda, Jenny J. Kim, Yan Zheng, Sattva S. Neelapu
Journal: Blood
Blood (2021) 138 (Supplement 1): 1764.
DOI: https://doi.org/10.1182/blood-2021-148078
Published: 2021
Journal Articles

Efficacy and Safety of Ciltacabtagene Autoleucel in Patients With Relapsed/Refractory Multiple Myeloma: CARTITUDE-1 Subgroup Analysis

Andrzej Jakubowiak, Saad Z. Usmani, Jesus G. Berdeja, Mounzer Agha, Adam D Cohen, Parameswaran Hari, Jordan M. Schecter, Deepu Madduri, Tzu-Min Yeh, Yunsi Olyslager, Arnob Banerjee, Carolyn C. Jackson, Alicia Allred, Enrique Zudaire, William Deraedt, Changwei Zhou, Dong Geng, Lida Pacaud, Yi Lin, Thomas Martin, Sundar Jagannath
Journal: Blood
Blood (2021) 138 (Supplement 1): 3938.
DOI: https://doi.org/10.1182/blood-2021-146069
Published: 2021
Journal Articles

Prophylactic Corticosteroid Use with Axicabtagene Ciloleucel (Axi-Cel) in Patients (Pts) with Relapsed/Refractory Large B-Cell Lymphoma (R/R LBCL): One-Year Follow-up of ZUMA-1 Cohort 6 (C6)

Olalekan O. Oluwole, Edouard Forcade, Javier Muñoz, Sophie de Guibert, Julie M. Vose, Nancy L. Bartlett, Yi Lin, Abhinav Deol, Peter A. McSweeney, Andre H. Goy, Marie José Kersten, Caron Jacobson, Umar Farooq, Monique C. Minnema, Catherine Thieblemont, John M. Timmerman, Patrick Stiff, Irit Avivi, Dimitrios Tzachanis, Jenny J. Kim, Yan Zheng, Rhine R. Shen, Saran Vardhanabhuti, Tom Van Meerten
Journal: Blood
Blood (2021) 138 (Supplement 1): 2832.
DOI: https://doi.org/10.1182/blood-2021-147403
Published: 2021
Journal Articles

Single Cell Transcriptome Profile of Myeloma and Immune Cell Characteristics in Patients with Durable Response Post CART

Yan Asmann, Ying Li, Taxiarchis Kourelis, Moritz Binder, Wilson I Gonsalves, Henan Zhang, Anatilde Gonzalez Guerrico, Zuoyi Shao, Prashant Kapoor, David Dingli, Rahma M Warsame, Haidong Dong, Shaji Kumar, Yi Lin
Journal: Blood
Blood (2021) 138 (Supplement 1): 3838.
DOI: https://doi.org/10.1182/blood-2021-153254
Published: 2021
Journal Articles

Response to Bridging Therapy As a Predictor of Outcomes for Chimeric Antigen Receptor Therapy in Large B-Cell Lymphoma

Arushi Khurana, Matthew Hathcock, Radhika Bansal, Yucai Wang, Jonas Paludo, Jose C. Villasboas, N. Nora Bennani, Patrick B. Johnston, Stephen M. Ansell, Yi Lin
Journal: Blood
Blood (2021) 138 (Supplement 1): 3841.
DOI: https://doi.org/10.1182/blood-2021-154186
Published: 2021
Journal Articles

Polatuzumab Vedotin Use before Chimeric Antigen Receptor T-Cell (CAR-T) Therapy in Aggressive Lymphoma: A US Single Center Experience

Arushi Khurana, Radhika Bansal, Matthew Hathcock, Adrienne Nedved, Yucai Wang, Jonas Paludo, Jose C Villasboas, N. Nora Bennani, Patrick B. Johnston, Stephen M. Ansell, Yi Lin
Journal: Blood
Blood (2021) 138 (Supplement 1): 3842.
DOI: https://doi.org/10.1182/blood-2021-152313
Published: 2021
Journal Articles

Peak Absolute Lymphocyte Count Post CAR-T Is Associated with Clinical Response and Survival Outcome in Aggressive Lymphoma

Radhika Bansal, Anatilde Gonzalez Guerrico, Henan Zhang, Zuoyi Shao, Elham Babadi, Kodi E Marinez, Gabrielle Gonzalez McCoy, Matthew A Hathcock, Arushi Khurana, N. Nora Bennani, Jonas Paludo, Yucai Wang, Stephen M. Ansell, Patrick B. Johnston, Jose C Villasboas, Yi Lin
Journal: Blood
Blood (2021) 138 (Supplement 1): 3856.
DOI: https://doi.org/10.1182/blood-2021-151295
Published: 2021
Journal Articles

Vaccine Titers in Lymphoma Patients Receiving Chimeric Antigen Receptor T Cell Therapy

Radhika Bansal, Paschalis Vergidis, Pritish K Tosh, John Wilson, Matthew Hathcock, Arushi Khurana, N. Nora Bennani, Jonas Paludo, Jose C. Villasboas, Yucai Wang, Stephen M. Ansell, Patrick B. Johnston, Catherine Freeman, Yi Lin
Journal: Blood
Blood (2021) 138 (Supplement 1): 3857.
DOI: https://doi.org/10.1182/blood-2021-153500
Published: 2021
Journal Articles

Impact of Achieving an Early Complete Response in Multiple Myeloma and Predictors of Subsequent Outcome

Marcella Kaddoura, Moritz Binder, David Dingli, Francis K. Buadi, Martha Q. Lacy, Morie A. Gertz, Angela Dispenzieri, Prashant Kapoor, Yi L. Hwa, Amie Fonder, Miriam A. Hobbs, Suzanne R. Hayman, Nelson Leung, Ronald Go, Yi Lin, Wilson I Gonsalves, Taxiarchis Kourelis, Rahma M Warsame, Robert A. Kyle, S. Vincent Rajkumar, Shaji Kumar
Journal: Blood
Blood (2021) 138 (Supplement 1): 3773.
DOI: https://doi.org/10.1182/blood-2021-151261
Published: 2021
Journal Articles

Primary Analysis of ZUMA-12: A Phase 2 Study of Axicabtagene Ciloleucel (Axi-Cel) As First-Line Therapy in Patients with High-Risk Large B-Cell Lymphoma (LBCL)

Sattva S. Neelapu, Michael Dickinson, Javier Munoz, Matthew L. Ulrickson, Catherine Thieblemont, Olalekan O. Oluwole, Alex F. Herrera, Chaitra S. Ujjani, Yi Lin, Peter A. Riedell, Natasha Kekre, Sven de Vos, Christine Lui, Francesca Milletti, Jinghui Dong, Hairong Xu, Julio C. Chavez
Journal: Blood
Blood (2021) 138 (Supplement 1): 739.
DOI: https://doi.org/10.1182/blood-2021-148009
Published: 2021
Journal Articles

Brexucabtagene Autoleucel for Relapsed/Refractory Mantle Cell Lymphoma: Real World Experience from the US Lymphoma CAR T Consortium

Yucai Wang, Preetesh Jain, Frederick L. Locke, Javier Munoz, Matthew J. Maurer, Amer Beitinjaneh, Matthew J. Frank, Saurabh Dahiya, Joseph P. McGuirk, Miriam T. Jacobs, Andre H. Goy, Julie M. Vose, Brian T. Hill, Olalekan O. Oluwole, Abhinav Deol, Bijal D. Shah, Jonas Paludo, Trent Wang, Lazaros J. Lekakis, David B. Miklos, Aaron P. Rapoport, Armin Ghobadi, Sattva S. Neelapu, Yi Lin, Michael Wang, Michael D. Jain
Journal: Blood
Blood (2021) 138 (Supplement 1): 744.
DOI: https://doi.org/10.1182/blood-2021-147563
Published: 2021
Journal Articles

The Impact of the Central Carbon Energy Metabolism Transcriptome in the Pathogenesis and Outcomes of Multiple Myeloma

Laura A Evans, Shaji Kumar, Erik Jessen, Angela Dispenzieri, Prashant Kapoor, Francis K. Buadi, David Dingli, Martha Q. Lacy, Suzanne R. Hayman, Nelson Leung, Eli Muchtar, Rahma M Warsame, Taxiarchis Kourelis, Stephen J. Russell, Yi Lin, Mustaqeem A. Siddiqui, Jin Sung Jang, Robert A. Kyle, S. Vincent Rajkumar, Morie A. Gertz, Rafael Fonseca, Wilson I Gonsalves
Journal: Blood
Blood (2021) 138 (Supplement 1): 2650.
DOI: https://doi.org/10.1182/blood-2021-147845
Published: 2021
Journal Articles

Prognostic Role of IL-6 in POEMS Syndrome

Maryam Omar, Rahma M Warsame, Morie A. Gertz, Francis K. Buadi, Ronald Go, Shaji Kumar, David Dingli, Robert A. Kyle, Nelson Leung, Taxiarchis Kourelis, Suzanne R. Hayman, Yi Lin, Martha Q. Lacy, John A. Lust, Yi L. Hwa, Amie Fonder, Prashant Kapoor, Miriam A. Hobbs, Wilson I Gonsalves, S. Vincent Rajkumar, Eli Muchtar, Alissa Visram, Stephen J. Russell, Angela Dispenzieri
Journal: Blood
Blood (2021) 138 (Supplement 1): 2700.
DOI: https://doi.org/10.1182/blood-2021-149792
Published: 2021
Journal Articles

Real-World Outcomes of Axicabtagene Ciloleucel (Axi-cel) for the Treatment of Large B-Cell Lymphoma (LBCL): Impact of Age and Specific Organ Dysfunction

Frederick L. Locke, Caron Jacobson, Long Ma, Hua Dong, Zhen-Huan Hu, Tanya Siddiqi, Sairah Ahmed, Armin Ghobadi, David B. Miklos, Yi Lin, Miguel-Angel Perales, Matthew A. Lunning, Megan M. Herr, Brian T. Hill, Siddhartha Ganguly, Abu-Sayeef Mirza, Sarah Nikiforow, Hairong Xu, Marcelo C Pasquini
Journal: Blood
Blood (2021) 138 (Supplement 1): 530.
DOI: https://doi.org/10.1182/blood-2021-149679
Published: 2021
Journal Articles

Updated Clinical and Correlative Results from the Phase I CRB-402 Study of the BCMA-Targeted CAR T Cell Therapy bb21217 in Patients with Relapsed and Refractory Multiple Myeloma

Noopur S. Raje, Nina Shah, Sundar Jagannath, Jonathan L. Kaufman, David S. Siegel, Nikhil C. Munshi, Jacalyn Rosenblatt, Yi Lin, Andrzej Jakubowiak, Alison Timm, Ashish Yeri, Nathan Martin, Timothy B. Campbell, Olivia Finney, Anna Truppel-Hartmann, Fabio Petrocca, Jesús G. Berdeja, Melissa Alsina
Journal: Blood
Blood (2021) 138 (Supplement 1): 548.
DOI: https://doi.org/10.1182/blood-2021-146518
Published: 2021
Journal Articles

Updated Results from CARTITUDE-1: Phase 1b/2Study of Ciltacabtagene Autoleucel, a B-Cell Maturation Antigen-Directed Chimeric Antigen Receptor T Cell Therapy, in Patients With Relapsed/Refractory Multiple Myeloma

Thomas Martin, Saad Z. Usmani, Jesús G. Berdeja, Andrzej Jakubowiak, Mounzer Agha, Adam D Cohen, Parameswaran Hari, David Avigan, Abhinav Deol, Myo Htut, Alexander Lesokhin, Nikhil C. Munshi, Elizabeth O'Donnell, A. Keith Stewart, Jordan M. Schecter, Jenna D. Goldberg, Carolyn C. Jackson, Tzu-Min Yeh, Arnob Banerjee, Alicia Allred, Enrique Zudaire, William Deraedt, Deepu Madduri, Yunsi Olyslager, Changwei Zhou, Lida Pacaud, Yi Lin, Sundar Jagannath
Journal: Blood
Blood (2021) 138 (Supplement 1): 549.
DOI: https://doi.org/10.1182/blood-2021-146060
Published: 2021
Journal Articles

Ciltacabtagene Autoleucel for Triple-Class Exposed Multiple Myeloma: Adjusted Comparisons of CARTITUDE-1 Patient Outcomes Versus Therapies from Real-World Clinical Practice from the LocoMMotion Prospective Study

Maria-Victoria Mateos, Katja Weisel, Thomas Martin, Jesús G. Berdeja, Andrzej Jakubowiak, A. Keith Stewart, Sundar Jagannath, Yi Lin, Joris Diels, Francesca Ghilotti, Nolen J Perualila, Jedelyn Cabrieto, Benjamin Haefliger, Nichola Erler-Yates, Clare Hague, Carolyn C. Jackson, Vadim Strulev, Tonia Nesheiwat, Lida Pacaud, Philippe Moreau, Hermann Einsele
Journal: Blood
Blood (2021) 138 (Supplement 1): 550.
DOI: https://doi.org/10.1182/blood-2021-146200
Published: 2021