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Thomas D. Coates
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Journal Articles

Effect of Luspatercept on Red Blood Cell (RBC) Transfusion Burden, Iron Chelation Therapy (ICT), and Iron Overload in Adults with Transfusion-Dependent β-Thalassemia (TDT) from the BELIEVE Trial: A Long-Term Analysis

Olivier Hermine, Maria Domenica Domenica Cappellini, Ali T. Taher, Thomas D. Coates, Vip Viprakasit, Antonis Kattamis, Jeevan K. Shetty, Marija Bosilkovska Weisskopf, Natalia Holot, Sadanand Vodala, Wen-Ling Kuo, John B. Porter
Journal: Blood
Blood (2022) 140 (Supplement 1): 8215–8217.
DOI: https://doi.org/10.1182/blood-2022-156985
Published: 2022
Journal Articles

Erythroid Response in Patients with Non-Transfusion-Dependent β-Thalassemia Treated with Luspatercept: Long-Term Data from the BEYOND Trial

Ali T. Taher, Vip Viprakasit, Maria Domenica Domenica Cappellini, Antonio Piga, John B. Porter, Thomas D. Coates, Khaled M. Musallam, Gian Luca Forni, Jeevan K. Shetty, Marija Bosilkovska Weisskopf, Richard Wei, Wen-Ling Kuo, Antonis Kattamis
Journal: Blood
Blood (2022) 140 (Supplement 1): 8210–8212.
DOI: https://doi.org/10.1182/blood-2022-157512
Published: 2022
Journal Articles

Effect of Luspatercept in β-Thalassemia Patients with β0/β0 Genotype: A Subgroup Analysis of the BELIEVE Study

Sujit Sheth, Olivier Hermine, Ali T. Taher, Kevin H.M. Kuo, John B. Porter, Antonio Piga, Thomas D. Coates, Antonis Kattamis, Loyse Felber Medlin, Wen-Ling Kuo, Natalia Holot, Maria Domenica Domenica Cappellini
Journal: Blood
Blood (2022) 140 (Supplement 1): 1946–1948.
DOI: https://doi.org/10.1182/blood-2022-157511
Published: 2022
Journal Articles

Early initiation of disease-modifying therapy can impede or prevent diffuse myocardial fibrosis in sickle cell anemia

Clinical Trials & Observations
Omar Niss, Jon Detterich, John C. Wood, Thomas D. Coates, Punam Malik, Michael D. Taylor, Charles T. Quinn
Journal: Blood
Blood (2022) 140 (11): 1322–1324.
DOI: https://doi.org/10.1182/blood.2021015303
Published: 2022
Includes: Supplemental data
Journal Articles

Luspatercept Improves Quality of Life and Reduces Red Blood Cell Transfusion Burden in Patients with Non-Transfusion-Dependent β-Thalassemia in the BEYOND Trial

Antonis Kattamis, Vip Viprakasit, Maria Domenica Cappellini, Ersi Voskaridou, Antonio Piga, John B. Porter, Thomas D. Coates, Gian Luca Forni, Jeevan K. Shetty, Dimana Miteva, Oriana Esposito, Wen-Ling Kuo, Shien Guo, Christopher Pelligra, Jennifer Lord-Bessen, Aylin Yucel, Ali T. Taher
Journal: Blood
Blood (2021) 138 (Supplement 1): 3081.
DOI: https://doi.org/10.1182/blood-2021-148535
Published: 2021
Journal Articles

A Phase 2a Study Evaluating the Safety and Pharmacokinetics (PK) of Luspatercept in Pediatric Patients with Transfusion-Dependent β-Thalassemia (TDT)

Vip Viprakasit, Thomas D. Coates, Khaled M. Musallam, Julie Vienne Buerki, Meera Patturajan, Natalia Holot, Yesim Aydinok
Journal: Blood
Blood (2021) 138 (Supplement 1): 4161.
DOI: https://doi.org/10.1182/blood-2021-145698
Published: 2021
Journal Articles

Trial in Progress: A Phase 2, Open-Label Study Evaluating the Safety and Efficacy of the PKR Activator Etavopivat (FT-4202) in Patients with Thalassemia or Sickle Cell Disease

Ashutosh Lal, R. Clark Clark Brown, Thomas D. Coates, Theodosia A. Kalfa, Janet L. Kwiatkowski, Julie Brevard, Von Potter, Ken W. Wood, Sujit Sheth
Journal: Blood
Blood (2021) 138 (Supplement 1): 4162.
DOI: https://doi.org/10.1182/blood-2021-145752
Published: 2021
Journal Articles

Longitudinal Effect of Luspatercept Treatment on Iron Overload and Iron Chelation Therapy (ICT) in Adult Patients (Pts) with β-Thalassemia in the Believe Trial

Olivier Hermine, Maria Domenica Cappellini, Ali T. Taher, Thomas D. Coates, MD, Vip Viprakasit, Ersi Voskaridou, Ashutosh Lal, MD, Hong Keng Liew, Silverio Perrotta, Abderrahim Khelif, Antonis Kattamis, Jeevan K. Shetty, George Zhang, Yu (Olivia) Tian, Dimana Miteva, Tatiana Zinger, Derek Tang, Jay T. Backstrom, John B. Porter, MA, MD, FRCP, FRCPath
Journal: Blood
Blood (2020) 136 (Supplement 1): 47–48.
DOI: https://doi.org/10.1182/blood-2020-136517
Published: 2020
Journal Articles

Loss of Alpha Globin Genes in Human Subjects Is Associated with Improved Nitric Oxide-Mediated Vascular Perfusion

Christopher C Denton, MD, Payal Shah, MS, Silvie Suriany, MS, Honglei Liu, MS, Wanwara Thuptimdang, MS, John Sunwoo, PhD, Patjanaporn Chalacheva, PhD, Saranya Veluswamy, MD, Roberta Miyeko Kato, MD, John C Wood, MD PhD, Jon A Detterich, MD, Michael C.K. Khoo, PhD, Thomas D. Coates, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 6–7.
DOI: https://doi.org/10.1182/blood-2020-136745
Published: 2020
Journal Articles

Sustained Reductions in Red Blood Cell (RBC) Transfusion Burden and Events in β-Thalassemia with Luspatercept: Longitudinal Results of the Believe Trial

Ali T. Taher, Vip Viprakasit, Olivier Hermine, John B. Porter, MA, MD, FRCP, FRCPath, Antonio Piga, MD, Kevin H.M. Kuo, MDMSc,FRCPC, Thomas D. Coates, MD, Ersi Voskaridou, Abderrahim Khelif, Antonis Kattamis, Jeevan K. Shetty, George Zhang, Yu (Olivia) Tian, Dimana Miteva, Tatiana Zinger, Derek Tang, Jay T. Backstrom, Maria Domenica Cappellini
Journal: Blood
Blood (2020) 136 (Supplement 1): 45–46.
DOI: https://doi.org/10.1182/blood-2020-140310
Published: 2020
Journal Articles

Progressive vasoconstriction with sequential thermal stimulation indicates vascular dysautonomia in sickle cell disease

Saranya Veluswamy, Payal Shah, Maha Khaleel, Wanwara Thuptimdang, Patjanaporn Chalacheva, John Sunwoo, Christopher C. Denton, Roberta Kato, Jon Detterich, John C. Wood, Richard Sposto, Michael C. K. Khoo, Lonnie Zeltzer, Thomas D. Coates
Journal: Blood
Blood (2020) 136 (10): 1191–1200.
DOI: https://doi.org/10.1182/blood.2020005045
Published: 2020
Includes: Supplemental data
Journal Articles

Introduction to a review series on human neutrophils

Nancy Berliner, Thomas D. Coates
Journal: Blood
Blood (2019) 133 (20): 2111–2112.
DOI: https://doi.org/10.1182/blood-2019-01-891770
Published: 2019
Journal Articles

Introduction to a review series on iron metabolism and its disorders

Clinical Trials & Observations
Thomas D. Coates, Mario Cazzola
Journal: Blood
Blood (2019) 133 (1): 1–2.
DOI: https://doi.org/10.1182/blood-2018-10-876466
Published: 2019
Journal Articles

The Believe Trial: Results of a Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Luspatercept in Adult Beta-Thalassemia Patients Who Require Regular Red Blood Cell (RBC) Transfusions

Maria Domenica Cappellini, MD, Vip Viprakasit, MD DPhil, Ali Taher, MDPhD, Pencho Georgiev, MD, Kevin H. M. Kuo, MDMSc,FRCPC, Thomas D. Coates, MD, Ersi Voskaridou, MD, Hong Keng Liew, Idit Pazgal-Kobrowski, Gianluca Forni, Silverio Perrotta, Abderrahim Khelif, Ashutosh Lal, MD, Antonis Kattamis, Efthymia Vlachaki, Raffaella Origa, MD, Yesim Aydinok, Mohamed Bejaoui, P. Joy Ho, Lee Ping Chew, Ping Chong Bee, Soo Min Lim, Meng-Yao Lu, Adisak Tantiworawit, Penka Ganeva, Liana Gercheva, Farrukh Shah, Ellis J. Neufeld, Abderrahmane Laadem, MD, Jeevan K. Shetty, Jun Zou, MDPhD, Dimana Miteva, PhD, Tatiana Zinger, PhD, Peter G. Linde, Matthew L. Sherman, Olivier Hermine, MDPhD, John Porter, MA MDFRCP FRCPath, Antonio Piga
Journal: Blood
Blood (2018) 132 (Supplement 1): 163.
DOI: https://doi.org/10.1182/blood-2018-163
Published: 2018
Journal Articles

Sickle Cell Subjects Have a Stronger and Faster Neurally Mediated Vasoconstriction Response to Cold Pain That Correlates with Anxiety Scores

Saranya Veluswamy, MD, Payal Shah, MS, Maha Khaleel, MD, Mammen Puliyel, MD MBBS, Wanwara Thuptimdang, MS, Patjanaporn Chalacheva, PhD, John Sunwoo, MS, Christopher Clement Denton, MD, Roberta Miyeko Kato, MD, Jon A Detterich, MD, John C Wood, MD PhD, Richard Sposto, PhD, Michael Khoo, PhD, Lonnie Zeltzer, MD, Thomas D. Coates, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 854.
DOI: https://doi.org/10.1182/blood-2018-99-113655
Published: 2018
Journal Articles

Hemolysis and Tricuspid Regurgitation Jet Velocity Predict Mortality in Patients with Sickle Cell Disease

Payal Shah, MS, Adam Bush, PhD, Silvie Suriany, MS, Honglei Liu, MS, Henry J Forman, PhD, Patjanaporn Chalacheva, PhD, Wanwara Thuptimdang, MS, John Sunwoo, MS, Saranya Veluswamy, MD, Christopher Clement Denton, MD, Maha Khaleel, MD, Roberta Miyeko Kato, MD, Ajay Perumbeti, MD, Richard Sposto, PhD, Michael Khoo, PhD, Thomas D. Coates, MD, John C Wood, MD PhD, Jon A Detterich, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1086.
DOI: https://doi.org/10.1182/blood-2018-99-119587
Published: 2018
Journal Articles

Middle Cerebral Artery Velocities Are Inversely Related to Hemoglobin Levels and Acutely Drop in Response to RBC Transfusion: Implications for Stroke Screening in SCD

Ajay Perumbeti, MD, Obdulio Carreras, BS, Jon A Detterich, MD, Payal Shah, MS, John Sunwoo, MS, Michael Khoo, PhD, John C Wood, MD PhD, Thomas D. Coates, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2374.
DOI: https://doi.org/10.1182/blood-2018-99-115485
Published: 2018
Journal Articles

Introduction to a How I Treat series on sickle cell disease and thalassemia

Thomas D. Coates
Journal: Blood
Blood (2018) 132 (17): 1729–1730.
DOI: https://doi.org/10.1182/blood-2018-08-858118
Published: 2018
Journal Articles

Increased brain iron deposition in patients with sickle cell disease: an MRI quantitative susceptibility mapping study

Xin Miao, Soyoung Choi, Benita Tamrazi, Yaqiong Chai, Chau Vu, Thomas D. Coates, John C. Wood
Journal: Blood
Blood (2018) 132 (15): 1618–1621.
DOI: https://doi.org/10.1182/blood-2018-04-840322
Published: 2018
Includes: Supplemental data
Journal Articles

Chronic Anemia Is Associated with Lower Cerebral and Peripheral Arterio-Venous Oxygen Gradients

Chau Vu, BS, Adam Bush, PhD, Soyoung Choi, BA, Xin Miao, BS, Thomas D. Coates, MD, John C Wood, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3542.
DOI: https://doi.org/10.1182/blood.V130.Suppl_1.3542.3542
Published: 2017