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Journal Articles

Natural History and Predictors of Survival in Adult Patients with Telomere Biology Disorders

Enrica Quattrocchi, Eva M. Carmona Porquera, Alejandro Diaz Arumir Vergara, Ana C. Zamora, Laura Ongie, Kristen B. McCullough, Brittany Burnap, Jenna A. Fernandez, Doug A. Simonetto, Patrick S. Kamath, Avni Joshi, Mark E. Wylam, Cassie C. Kennedy, Terra L. Lasho, Christy Finke, Rachel A. Simon, Mrinal M. Patnaik, Alejandro Ferrer, Abhishek A. Mangaonkar

Blood (2024) 144 (Supplement 1): 1326.

https://doi.org/10.1182/blood-2024-210391

Published: 2024

Journal Articles

DNMT3A Mutant Clonal Hematopoiesis in Vexas Syndrome Epigenetically Potentiates IL-13 and IL-15 Inflammatory Pathways and Is Associated with Increased Mortality

Blood (2024) 144 (Supplement 1): 2686.

https://doi.org/10.1182/blood-2024-204334

Published: 2024

Journal Articles

Preclinical Evaluation of Stx-0712, a CCR2 Cytotoxicity Targeting Chimera (CCR2-CyTAC) for the Treatment of Chronic Myelomonocytic Leukemia

Brandon Turunen, Craig Leach, Matthew Smith, Terra L. Lasho, Christy Finke, Abhishek A. Mangaonkar, Aref Al-Kali, Yael Kusne, Talha Badar, James M. Foran, Aisha Margaert, Michelle Baptista, Stephanie Wiltzius, Mrinal M. Patnaik

Blood (2024) 144 (Supplement 1): 2771.

https://doi.org/10.1182/blood-2024-209024

Published: 2024

Journal Articles

PPM1D Somatic Mutations in Myeloid Neoplasms: Clinical Profile, Clonal Characteristics and Impact of Concurrent Somatic TP53 Mutations

Blood (2024) 144 (Supplement 1): 3218.

https://doi.org/10.1182/blood-2024-202688

Published: 2024

Journal Articles

Predictors of Blast Transformation (BT) and Post-BT Survival in Chronic Myelomonocytic Leukemia (CMML)

Anuya A. Natu, Clifford M. Csizmar, Terra L. Lasho, Rashmi Kanagal-Shamanna, Sanam Loghavi, Alexandre Bazinet, Kelly S. Chien, Danielle Hammond, Christy Finke, Aref Al-Kali, Hassan B Alkhateeb, Naseema Gangat, Abhishek A. Mangaonkar, Antoine N. Saliba, Ayalew Tefferi, Guillermo Garcia-Manero, Hagop Kantarjian, Guillermo Montalban-Bravo, Mrinal M. Patnaik

Blood (2024) 144 (Supplement 1): 4593.

https://doi.org/10.1182/blood-2024-209236

Published: 2024

Journal Articles

PHF6 Mutation in Chronic Myelomonocytic Leukemia Is Associated with Chronic Thrombocytopenia and Predicts Superior Overall and Leukemia-Free Survival

Saubia Fathima, Ali Alsugair, Anuya A. Natu, Clifford M. Csizmar, Mark Gurney, Terra L. Lasho, Christy Finke, Abhishek A. Mangaonkar, Kaaren K. Reichard, Rong He, Animesh D. Pardanani, Naseema Gangat, Mrinal M. Patnaik, Ayalew Tefferi

Blood (2024) 144 (Supplement 1): 4586.

https://doi.org/10.1182/blood-2024-206007

Published: 2024

Journal Articles

Landscape and Clinicopathologic Features of RAS Pathway Mutations in Chronic Myelomonocytic Leukemia

Blood (2024) 144 (Supplement 1): 3204.

https://doi.org/10.1182/blood-2024-208890

Published: 2024

Journal Articles

Clinical Characteristics of Myeloproliferative Neoplasms in Patients with DDX41 MT Germline Predisposition Syndrome

Yael Kusne, Talha Badar, Terra L. Lasho, Ludovica Marando, Abhishek A. Mangaonkar, Christy Finke, James M. Foran, Aref Al-Kali, Hassan B Alkhateeb, Naseema Gangat, Jeanne Palmer, David Viswanatha, Mark R. Litzow, Animesh D. Pardanani, Ayalew Tefferi, Timothy Chlon, Alejandro Ferrer, Mrinal M. Patnaik

Blood (2024) 144 (Supplement 1): 3183.

https://doi.org/10.1182/blood-2024-202406

Published: 2024

Journal Articles

Targeting Aberrant DLK1 Re-Expression in ASXL1 -Mutant Chronic Myelomonocytic Leukemia with BRD4 / p300-Directed Epigenetic Small Molecule Therapy

Terra L. Lasho, Jenna A. Fernandez, Jeong-Heon Lee, Linh D. Pham, Huihuang Yan, Christy Finke, Abhishek A. Mangaonkar, Aref Al-Kali, Naseema Gangat, Joseph Collard, Claes Wahlestedt, Mrinal M. Patnaik, Moritz Binder

Blood (2024) 144 (Supplement 1): 3197.

https://doi.org/10.1182/blood-2024-204070

Published: 2024

Journal Articles

Phase II Trial Assessing Safety and Preliminary Efficacy of High-Dose Intravenous Ascorbic Acid and Decitabine in TET2 -Mutant Chronic Myelomonocytic Leukemia

Kristen B. McCullough, Zhuoer Xie, Terra L. Lasho, Christy Finke, Jenna A. Fernandez, Michelle Renee Amundson, Betsy R. LaPlant, Thomas E. Witzig, Mrinal M. Patnaik

Blood (2024) 144 (Supplement 1): 6699.

https://doi.org/10.1182/blood-2024-203486

Published: 2024

Journal Articles

Prognostic Impact of the Number of TET2 Mutations in Myelodysplastic and Myeloproliferative Chronic Myelomonocytic Leukemia (CMML)

Blood (2024) 144 (Supplement 1): 1820.

https://doi.org/10.1182/blood-2024-209193

Published: 2024

Journal Articles

Revised Mayo Molecular Risk Model for Chronic Myelomonocytic Leukemia (MMM version 2.0): A Combined Clinical, Cytogenetic, and Mutational Platform

Ayalew Tefferi, Saubia Fathima, Ali Khalid Alsugair, Clifford M. Csizmar, Mark Gurney, Terra L. Lasho, Christy Finke, Abhishek A. Mangaonkar, Aref Al-Kali, Hassan B Alkhateeb, Kaaren K. Reichard, Animesh D. Pardanani, Naseema Gangat, Mrinal M. Patnaik

Blood (2024) 144 (Supplement 1): 1827.

https://doi.org/10.1182/blood-2024-207736

Published: 2024

Journal Articles

Prevalence and Clinical Features of Non-Myeloid Neoplasms in Patients with DDX41 Mutant Germline Predisposition Syndrome

Blood (2024) 144 (Supplement 1): 440.

https://doi.org/10.1182/blood-2024-203879

Published: 2024

Journal Articles

Clonal Hematopoiesis Landscape in Metastatic Prostate Cancer Patients

Yael Kusne, Osama Mosalem, Kevin Thompson, Krishna Kalari, Winston Tan, Leila A Jones, Brian A Costello, Daniel Childs, Abhishek A. Mangaonkar, Jenna A. Fernandez, Christy Finke, Terra L. Lasho, Richard Weinshilboum, Leiwei Wang, Mrinal M. Patnaik

Blood (2024) 144 (Supplement 1): 5644.

https://doi.org/10.1182/blood-2024-206483

Published: 2024

Journal Articles

A Prospective Cohort Study of Biologic and Chronologic Aging in 106 Patients with Age and Context-Relevant Clonal Hematopoiesis

Marissa Li, Jenna A. Fernandez, Kristina Kirschner, Tamir Chandra, Kristen B. McCullough, Sarah Aug, Terra L. Lasho, Christy Finke, Naseema Gangat, Abhishek A. Mangaonkar, Rachel A Simon, Alejandro Ferrer, Mrinal M. Patnaik, James M. Foran, Cecilia Y. Arana Yi, Yael Kusne, Talha Badar

Blood (2024) 144 (Supplement 1): 5632.

https://doi.org/10.1182/blood-2024-206069

Published: 2024

Journal Articles

Comparative Analysis of Oligomonocytic CMML with Myelodysplastic and Myeloproliferative CMML Subtypes: A Study of 849 Molecularly-Annotated Patients

Clifford M. Csizmar, Anuya A. Natu, Rashmi Kanagal-Shamanna, Kelly S. Chien, Danielle Hammond, Sanam Loghavi, Alexandre Bazinet, Terra L. Lasho, Christy Finke, Aref Al-Kali, Hassan B Alkhateeb, Naseema Gangat, Abhishek A. Mangaonkar, Antoine N. Saliba, Ayalew Tefferi, Guillermo Garcia-Manero, Hagop Kantarjian, Guillermo Montalban-Bravo, Mrinal M. Patnaik

Blood (2024) 144 (Supplement 1): 6747.

https://doi.org/10.1182/blood-2024-209126

Published: 2024

Journal Articles

Targeting Oncogenic Enhancers in ASXL1 -Mutant Chronic Myelomonocytic Leukemia

Terra L Lasho, Christy M Finke, Jenna A. Fernandez, Christopher T. Schmitz, Karl J. Clark, Claes Wahlestedt, Judy Chiao, Abhishek A Mangaonkar, Mrinal M. Patnaik, Moritz Binder

Blood (2023) 142 (Supplement 1): 1413.

https://doi.org/10.1182/blood-2023-178083

Published: 2023

Journal Articles

ASXL1 / TET2 Genotype-Based Risk Stratification Outperforms ASXL1 Mutational Impact and Is Independent of Mutant Variant Allele Fractions (VAF) in CMML

Clifford M Csizmar, Mark Gurney, Rashmi Kanagal-Shamanna, Kelly S. Chien, Danielle E. Hammond, Terra L Lasho, Christy M Finke, Christopher Dean, Abhishek A Mangaonkar, Naseema Gangat, Ayalew Tefferi, Hassan Alkhateeb, Guillermo Garcia-Manero, Guillermo Montalban-Bravo, Mrinal M. Patnaik

Blood (2023) 142 (Supplement 1): 4615.

https://doi.org/10.1182/blood-2023-187235

Published: 2023

Journal Articles

Clinical and Molecular Spectrum of Somatic Mosaic States in DDX41 mutant Germline Predisposition Syndromes

Talha Badar, Terra L Lasho, Yael Kusne, Ludovica Marando, Abhishek A Mangaonkar, Christy M Finke, James M. Foran, Aref Al-Kali, Hassan Alkhateeb, Naseema Gangat, Rong He, David Viswanatha, Mark R. Litzow, Timothy Chlon, Alejandro Ferrer, Mrinal M. Patnaik

Blood (2023) 142 (Supplement 1): 4618.

https://doi.org/10.1182/blood-2023-187310

Published: 2023

Journal Articles

Distribution of Chromosome-Arm Specific Telomere Length in Patients with Telomere Biology Disorders

Alejandro Ferrer, Zachary D Stephens, Susan M. Geyer, Rachel A Simon, Terra L Lasho, Christy M Finke, Brittany Burnap, Lindsay A Mulvihill, Tammy M McAllister, Carolyn R. Rohrer Vitek, Konstantinos N Lazaridis, Angita Jain, Eric W Klee, Jean-Pierre A Kocher, Mrinal M. Patnaik

Blood (2023) 142 (Supplement 1): 4103.

https://doi.org/10.1182/blood-2023-187486

Published: 2023

NARROW

Natural History and Predictors of Survival in Adult Patients with Telomere Biology Disorders

DNMT3A Mutant Clonal Hematopoiesis in Vexas Syndrome Epigenetically Potentiates IL-13 and IL-15 Inflammatory Pathways and Is Associated with Increased Mortality

Preclinical Evaluation of Stx-0712, a CCR2 Cytotoxicity Targeting Chimera (CCR2-CyTAC) for the Treatment of Chronic Myelomonocytic Leukemia

PPM1D Somatic Mutations in Myeloid Neoplasms: Clinical Profile, Clonal Characteristics and Impact of Concurrent Somatic TP53 Mutations

Predictors of Blast Transformation (BT) and Post-BT Survival in Chronic Myelomonocytic Leukemia (CMML)

PHF6 Mutation in Chronic Myelomonocytic Leukemia Is Associated with Chronic Thrombocytopenia and Predicts Superior Overall and Leukemia-Free Survival

Landscape and Clinicopathologic Features of RAS Pathway Mutations in Chronic Myelomonocytic Leukemia

Clinical Characteristics of Myeloproliferative Neoplasms in Patients with DDX41 MT Germline Predisposition Syndrome

Targeting Aberrant DLK1 Re-Expression in ASXL1 -Mutant Chronic Myelomonocytic Leukemia with BRD4 / p300-Directed Epigenetic Small Molecule Therapy

Phase II Trial Assessing Safety and Preliminary Efficacy of High-Dose Intravenous Ascorbic Acid and Decitabine in TET2 -Mutant Chronic Myelomonocytic Leukemia

Prognostic Impact of the Number of TET2 Mutations in Myelodysplastic and Myeloproliferative Chronic Myelomonocytic Leukemia (CMML)

Revised Mayo Molecular Risk Model for Chronic Myelomonocytic Leukemia (MMM version 2.0): A Combined Clinical, Cytogenetic, and Mutational Platform

Prevalence and Clinical Features of Non-Myeloid Neoplasms in Patients with DDX41 Mutant Germline Predisposition Syndrome

Clonal Hematopoiesis Landscape in Metastatic Prostate Cancer Patients

A Prospective Cohort Study of Biologic and Chronologic Aging in 106 Patients with Age and Context-Relevant Clonal Hematopoiesis

Comparative Analysis of Oligomonocytic CMML with Myelodysplastic and Myeloproliferative CMML Subtypes: A Study of 849 Molecularly-Annotated Patients

Targeting Oncogenic Enhancers in ASXL1 -Mutant Chronic Myelomonocytic Leukemia

ASXL1 / TET2 Genotype-Based Risk Stratification Outperforms ASXL1 Mutational Impact and Is Independent of Mutant Variant Allele Fractions (VAF) in CMML

Clinical and Molecular Spectrum of Somatic Mosaic States in DDX41 mutant Germline Predisposition Syndromes

Distribution of Chromosome-Arm Specific Telomere Length in Patients with Telomere Biology Disorders

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American Society of Hematology

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