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Steven M. Kornblau
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Journal Articles

Proteomics-Based Strategy for the Recommendation of Conventional Chemotherapy Vs Venetoclax Plus Hypomethylating Agents in Adult Acute Myeloid Leukemia (AML)

Eduardo Sabino de Camargo Magalhaes, Brandon D Brown, Stefan Hubner, Yihua Qiu, Steven M. Kornblau
Journal: Blood
Blood (2022) 140 (Supplement 1): 6312–6313.
https://doi.org/10.1182/blood-2022-165158
Published: 2022
Journal Articles

RPPA-Profiling in Pediatric and Adult T-Cell Acute Lymphoblastic Leukemia Identifies Protein Patterns Associated with Outcome

Fieke W Hoff, Lourdes Sriraja, Yihua Qiu, Gaye Jenkins, Andrew Ligeralde, David T. Teachey, Brent L. Wood, Meenakshi Devidas, Mignon L. Loh, Todd A. Alonzo, Amina A Qutub, Evangelia Petsalaki, Steven M. Kornblau, Terzah M. Horton
Journal: Blood
Blood (2022) 140 (Supplement 1): 6352–6353.
https://doi.org/10.1182/blood-2022-163881
Published: 2022
Journal Articles

Intracellular IL-23 Receptor (IL-23R) Is Necessary for AML Viability and Regulates Mitotic Spindle and Centrosome Formation

Nathan Duong, Dilshad H. Khan, Geethu Emily Thomas, Rose Hurren, Jong Bok Lee, Jonathan St-Germain, Lily Drimmer, Yongran Yan, Neil MacLean, Marcela Gronda, Brandon D Brown, Brian Raught, Andrea Arruda, Mark D. Minden, Li Zhang, Steven M. Kornblau, Vito Spadevecchio, Aaron D. Schimmer
Journal: Blood
Blood (2022) 140 (Supplement 1): 3005–3006.
https://doi.org/10.1182/blood-2022-157626
Published: 2022
Journal Articles

Targeting Vimentin (VIM) in Acute Myelogenous Leukemia (AML)

Stefan Hubner, Marina Konopleva, Zhihong Zeng, Fieke W Hoff, Yihua Qiu, Vivian Ruvolo, Terzah M. Horton, Steven M. Kornblau
Journal: Blood
Blood (2022) 140 (Supplement 1): 6260–6261.
https://doi.org/10.1182/blood-2022-163664
Published: 2022
Journal Articles

Phase 2 Study of ASTX727 (cedazuridine/decitabine) Plus Venetoclax in Patients with Relapsed/Refractory Acute Myeloid Leukemia (AML) or Previously Untreated, Elderly Patients with AML Unfit for Chemotherapy

Tareq Abuasab, Guillermo Garcia-Manero, Nicholas Short, Yesid Alvarado, Ghayas C. Issa, Rubiul Islam, Abhishek Maiti, Musa Yilmaz, Nitin Jain, Lucia Masarova, Steven M. Kornblau, Elias Jabbour, Naveen Pemmaraju, Guillermo Montalban-Bravo, Sherry A. Pierce, Courtney D. DiNardo, Tapan M. Kadia, Naval Daver, Marina Konopleva, Hagop Kantarjian, Farhad Ravandi
Journal: Blood
Blood (2022) 140 (Supplement 1): 3324–3326.
https://doi.org/10.1182/blood-2022-158566
Published: 2022
Journal Articles

The Exportin, XPO2, Is a Novel Therapeutic Target in Pediatric, Adolescent and Young Adult AML

Grace Egan, Rose Hurren, Chaitra Sarathy, Geethu Emily Thomas, Dilshad H. Khan, Yongran Yan, Yue Feng, Brandon Brown, Steven M. Kornblau, Aaron D. Schimmer
Journal: Blood
Blood (2022) 140 (Supplement 1): 11504–11505.
https://doi.org/10.1182/blood-2022-157322
Published: 2022
Journal Articles

Epigenetic Landscape Predicts Overall Survival and Remission Duration in Adult Acute Myeloid Leukemia

Eduardo Sabino de Camargo Magalhaes, Yihua Qiu, Steven M. Kornblau
Journal: Blood
Blood (2022) 140 (Supplement 1): 6331–6332.
https://doi.org/10.1182/blood-2022-169962
Published: 2022
Journal Articles

Chromatin Accessibility Landscapes of B-Cell Acute Lymphoblastic Leukemia Identify Extensive Epigenomic Reprogramming and Heterogeneity Among Subtypes

Kelly R. Barnett, Jonathan D. Diedrich, Brennan P. Bergeron, Wenjian Yang, Kristine R. Crews, Wendy Stock, Elisabeth Paietta, Steven M. Kornblau, Hiroto Inaba, Sima Jeha, Ching-Hon Pui, Mary V. Relling, William E. Evans, Jun J.J. Yang, Daniel Savic
Journal: Blood
Blood (2022) 140 (Supplement 1): 5907–5908.
https://doi.org/10.1182/blood-2022-166528
Published: 2022
Journal Articles

First in Human Study of Anti-Viral Veto Cells Enabling Successful Engraftment without Severe Gvhd in Non-Myeloablative T Cell Depleted Haploidentical Hematopoietic Stem Cell Transplantation (HSCT)

Richard E Champlin, Esther Bachar Lustig, Qaiser Bashir, Betul Oran, Steven M. Kornblau, Chitra Hosing, Amin M Alousi, Uday R Popat, Jessica M McCarty, Peter F Thall, Bouthaina S. Dabaja, Wei-Hsin Liu, Giang Dang, Karla Castro, Alejandro Ramirez, Michael Spiotto, Susan Wu, Penny Fang, Indreshpal Kaur, Katy Rezvani, Elizabeth J Shpall, Yair Reisner
Journal: Blood
Blood (2022) 140 (Supplement 1): 2120–2122.
https://doi.org/10.1182/blood-2022-159183
Published: 2022
Journal Articles

The Addition of Inotuzumab Ozogamicin to Hyper-CVAD Plus Blinatumomab Further Improves Outcomes in Patients with Newly Diagnosed B-Cell Acute Lymphoblastic Leukemia: Updated Results from a Phase II Study

Nicholas Short, Elias Jabbour, Farhad Ravandi, Musa Yilmaz, Tapan M. Kadia, Philip A. Thompson, Xuelin Huang, Marina Konopleva, Alessandra Ferrajoli, Nitin Jain, Koji Sasaki, Walid Macaron, Yesid Alvarado, Gautam Borthakur, Courtney D. DiNardo, Maro Ohanian, Steven M. Kornblau, Min Zhao, Monica Kwari, Jennifer Thankachan, Christopher Loiselle, Ricardo Delumpa, Rebecca Garris, Hagop Kantarjian
Journal: Blood
Blood (2022) 140 (Supplement 1): 8966–8968.
https://doi.org/10.1182/blood-2022-157358
Published: 2022
Journal Articles

Venetoclax Combined with Cladribine, Idarubicin, Cytarabine (CLIA) As Induction Therapy in Patients with Newly Diagnosed Acute Myeloid Leukemia and High-Risk Myelodysplastic Syndrome

Patrick K Reville, Hagop Kantarjian, Gautam Borthakur, Musa Yilmaz, Naval Daver, Nicholas Short, Courtney D. DiNardo, Steven M. Kornblau, Naveen Pemmaraju, Nitin Jain, Yesid Alvarado, Prithviraj Bose, Elias Jabbour, Kelly S. Chien, Hussein A Abbas, Lucia Masarova, Sa A Wang, Rebecca S. S Tidwell, Michael Andreeff, Guillermo Garcia-Manero, Marina Konopleva, Farhad Ravandi, Tapan M. Kadia
Journal: Blood
Blood (2022) 140 (Supplement 1): 1702–1704.
https://doi.org/10.1182/blood-2022-167931
Published: 2022
Journal Articles

Updated Phase IIb Results of Venetoclax with FLAG-IDA in Relapsed or Refractory Acute Myeloid Leukemia

Sai Prasad Desikan, Marina Konopleva, Koichi Takahashi, Curtis A Lachowiez, Sanam Loghavi, Lian-Chun Xiao, Tapan M. Kadia, Naval Daver, Nicholas Short, Koji Sasaki, Gautam Borthakur, Ghayas C. Issa, Abhishek Maiti, Kelly S. Chien, Yesid Alvarado, Guillermo Montalban-Bravo, Lucia Masarova, Musa Yilmaz, Michael Andreeff, Elias Jabbour, Guillermo Garcia-Manero, Steven M. Kornblau, Farhad Ravandi, Hagop Kantarjian, Courtney D. DiNardo
Journal: Blood
Blood (2022) 140 (Supplement 1): 534–536.
https://doi.org/10.1182/blood-2022-164922
Published: 2022
Journal Articles

Epigenetic Fine Mapping and Functional Dissection of Inherited Non-Coding Variation Impacting the Pharmacogenomics of Acute Lymphoblastic Leukemia Treatment

Kashi Raj Bhattarai, Kelly R. Barnett, Robert J. Mobley, Daniel C. Ferguson, Jonathan D. Diedrich, Brennan P. Bergeron, Wenjian Yang, Kristine R. Crews, Wendy Stock, Elisabeth Paietta, Steven M. Kornblau, Hiroto Inaba, Sima Jeha, Ching-Hon Pui, Cheng Cheng, Mary V. Relling, William E. Evans, Jun J.J. Yang, Daniel Savic
Journal: Blood
Blood (2022) 140 (Supplement 1): 3027–3028.
https://doi.org/10.1182/blood-2022-167419
Published: 2022
Journal Articles

Effective therapy for AML with RUNX1 mutation by cotreatment with inhibitors of protein translation and BCL2

Christopher P. Mill, Warren Fiskus, Courtney D. DiNardo, Christine Birdwell, John A. Davis, Tapan M. Kadia, Koichi Takahashi, Nicholas Short, Naval Daver, Maro Ohanian, Gautam Borthakur, Steven M. Kornblau, Michael R. Green, Yuan Qi, Xiaoping Su, Joseph D. Khoury, Kapil N. Bhalla
Journal: Blood
Blood (2022) 139 (6): 907–921.
https://doi.org/10.1182/blood.2021013156
Published: 2022
Includes: Supplemental data
Journal Articles

BTK inhibition sensitizes acute lymphoblastic leukemia to asparaginase by suppressing the amino acid response pathway

Miriam Butler, Dorette S. van Ingen Schenau, Jiangyan Yu, Silvia Jenni, Maria P. Dobay, Rico Hagelaar, Britt M. T. Vervoort, Trisha M. Tee, Fieke W. Hoff, Jules P. Meijerink, Steven M. Kornblau, Beat Bornhauser, Jean-Pierre Bourquin, Roland P. Kuiper, Laurens T. van der Meer, Frank N. van Leeuwen
Journal: Blood
Blood (2021) 138 (23): 2383–2395.
https://doi.org/10.1182/blood.2021011787
Published: 2021
Includes: Supplemental data
Journal Articles

Final Results of a Phase 2 Study of Sotatercept (ACE-011) for Anemia of MPN-Associated Myelofibrosis

Prithviraj Bose, Lucia Masarova, Naveen Pemmaraju, Sharon D. Bledsoe, Naval Daver, Elias J. Jabbour, Tapan M. Kadia, Zeev E. Estrov, Steven M. Kornblau, Michael Andreeff, Jorge E. Cortes, Nitin Jain, Gautam Borthakur, Yesid Alvarado, Julie Huynh-Lu, Madeleine M. Nguyen-Cao, Mary Ann Richie, Mackenzie H. Dobbins, Selene Andrea McCrackin, Lingsha Zhou, Sherry A. Pierce, Xuemei Wang, Allison M. Pike, Guillermo Garcia-Manero, Hagop Kantarjian, Srdan Verstovsek
Journal: Blood
Blood (2021) 138 (Supplement 1): 144.
https://doi.org/10.1182/blood-2021-150908
Published: 2021
Journal Articles

Protein Expression Signatures Predict Response, Relapse, and Survival after Venetoclax Containing Therapy in Adults with Acute Myeloid Leukemia

Brandon Brown, Yihua Qiu, Fieke W Hoff, Steven M. Kornblau
Journal: Blood
Blood (2021) 138 (Supplement 1): 227.
https://doi.org/10.1182/blood-2021-153906
Published: 2021
Journal Articles

Updated Results from a Phase II Study of Mini-Hyper-CVD Plus Inotuzumab Ozogamicin, with or without Blinatumomab, in Older Adults with Newly Diagnosed Philadelphia Chromosome-Negative B-Cell Acute Lymphoblastic Leukemia

Nicholas J. Short, Hagop Kantarjian, Farhad Ravandi, Xuelin Huang, Nitin Jain, Tapan M. Kadia, Joseph D. Khoury, Jeffrey L. Jorgensen, Sa A Wang, Yesid Alvarado, Jan A. Burger, Naval Daver, Gautam Borthakur, Courtney D. DiNardo, Marina Konopleva, Naveen Pemmaraju, Guillermo Garcia-Manero, William G. Wierda, Steven M. Kornblau, Jovitta Jacob, Monica Kwari, Caitlin R. Rausch, Christopher Loiselle, Anna Milton, Juan Rivera, Rebecca Garris, Susan M. O'Brien, Elias J. Jabbour
Journal: Blood
Blood (2021) 138 (Supplement 1): 3400.
https://doi.org/10.1182/blood-2021-154074
Published: 2021
Journal Articles

A Phase I/II Study of Venetoclax in Combination with 5-Azacytidine in Treatment-Naïve and Relapsed/Refractory High-Risk Myelodysplastic Syndrome (MDS) or Chronic Myelomonocytic Leukemia (CMML)

Alexandre Bazinet, Elias J. Jabbour, Hagop Kantarjian, Kelly S. Chien, Courtney D. DiNardo, Maro Ohanian, Naval Daver, Rashmi Kanagal-Shamanna, Tapan M. Kadia, Koichi Takahashi, Lucia Masarova, Nicholas J. Short, Yesid Alvarado, Philip A. Thompson, Guillermo Montalban-Bravo, Musa Yilmaz, Farhad Ravandi, Steven M. Kornblau, Naveen Pemmaraju, Heather Schneider, Bailey Mirabella, Kiran Naqvi, Guillermo Garcia-Manero
Journal: Blood
Blood (2021) 138 (Supplement 1): 535.
https://doi.org/10.1182/blood-2021-153086
Published: 2021
Journal Articles

Phase II Trial of Ten-Day Decitabine with Venetoclax (DEC10-VEN) in Acute Myeloid Leukemia: Updated Outcomes in Genomic Subgroups

Abhishek Maiti, Courtney D. DiNardo, Caitlin R. Rausch, Naveen Pemmaraju, Guillermo Garcia-Manero, Maro Ohanian, Naval Daver, Ghayas C. Issa, Gautam Borthakur, Farhad Ravandi, Yesid Alvarado, Tapan M. Kadia, Elias J. Jabbour, Nicholas J. Short, Guillermo Montalban-Bravo, Nitin Jain, Steven M. Kornblau, Lucia Masarova, William G. Wierda, Koji Sasaki, Koichi Takahashi, Musa Yilmaz, Jan A. Burger, Zeev E. Estrov, Srdan Verstovsek, Michael Andreeff, Prithviraj Bose, Alessandra Ferrajoli, Philip A. Thompson, Kathryn Montalbano, Kenneth Vaughan, Carol A. Bivins, Sherry A. Pierce, Wei Qiao, Jing Ning, John S. Welch, Hagop Kantarjian, Marina Konopleva
Journal: Blood
Blood (2021) 138 (Supplement 1): 694.
https://doi.org/10.1182/blood-2021-153227
Published: 2021