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Souichi Adachi
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Journal Articles

Safety and Efficacy of Arsenic Trioxide in the Treatment of Newly Diagnosed Pediatric Acute Promyelocytic Leukemia: Results from the JPLSG AML-P13 Study

Hiroyuki Takahashi, Shiro Tanaka, Yuki Yuza, Yuka Iijima-Yamashita, Daisuke Hasegawa, Hiroshi Moritake, Kiminori Terui, Shotaro Iwamoto, Akira Shimada, Jun Matsubayashi, Takao Deguchi, Yoshiko Hashii, Nobutaka Kiyokawa, Hayato Miyachi, Akiko Moriya Saito, Takashi Taga, Souichi Adachi, Daisuke Tomizawa
Journal: Blood
Blood (2022) 140 (Supplement 1): 6160–6161.
DOI: https://doi.org/10.1182/blood-2022-162177
Published: 2022
Journal Articles

Prognosis of Pediatric Acute Myeloid Leukemia with KMT2A-MLLT3 According to DNA Methylation Patterns: Jccg JPLSG AML-05 Study

Genki Yamato, Tomoko Kawai, Norio Shiba, Yusuke Hara, Kentaro Ohki, Taeko Kaburagi, Etsuko Ishikita, Hirohide Kawasaki, Kenichi Yoshida, Yuichi Shiraishi, Satoru Miyano, Nobutaka Kiyokawa, Daisuke Tomizawa, Akira Shimada, Manabu Sotomatsu, Takumi Takizawa, Souichi Adachi, Takashi Taga, Keizo Horibe, Seishi Ogawa, Kenichiro Hata, Yasuhide Hayashi
Journal: Blood
Blood (2022) 140 (Supplement 1): 9134–9135.
DOI: https://doi.org/10.1182/blood-2022-163226
Published: 2022
Journal Articles

Evaluation of High-Dose Cytarabine Induction Therapy and Flow Cytometric Measurable Residual Disease Monitoring for Children with De Novo Acute Myeloid Leukemia: A Report from the JPLSG-AML-12 Trial

Daisuke Tomizawa, Shiro Tanaka, Shotaro Iwamoto, Hidefumi Hiramatsu, Jun Matsubayashi, Daisuke Hasegawa, Hiroshi Moritake, Daiichiro Hasegawa, Kiminori Terui, Asahito Hama, Shin-ichi Tsujimoto, Nobutaka Kiyokawa, Hayato Miyachi, Takao Deguchi, Yoshiko Hashii, Yuka Iijima-Yamashita, Tomohiko Taki, Yasushi Noguchi, Kazutoshi Koike, Katsuyoshi Koh, Yuki Yuza, Akiko Moriya Saito, Keizo Horibe, Takashi Taga, Souichi Adachi
Journal: Blood
Blood (2022) 140 (Supplement 1): 1450–1452.
DOI: https://doi.org/10.1182/blood-2022-158664
Published: 2022
Journal Articles

Clonal Evolution Pattern and Prognostic Significance of Clonal Architecture in KMT2A -Rearranged Acute Myeloid Leukemia

Hidemasa Matsuo, Kenichi Yoshida, Yasuhito Nannya, Yuri Ito, Shoji Saito, Yuhki Koga, Hiroshi Moritake, Kiminori Terui, Koji Kawaguchi, Yasuhiro Okamoto, Hideki Nakayama, Kanno Miyako, Moeko Hino, Yusuke Akane, Akiko Inoue, Akira Shimada, Hiroaki Goto, Hiroo Ueno, Junko Takita, Genki Yamato, Norio Shiba, Yasuhide Hayashi, Yuichi Shiraishi, Satoru Miyano, Nobutaka Kiyokawa, Daisuke Tomizawa, Takashi Taga, Akio Tawa, Seishi Ogawa, Souichi Adachi
Journal: Blood
Blood (2021) 138 (Supplement 1): 2358.
DOI: https://doi.org/10.1182/blood-2021-146699
Published: 2021
Journal Articles

RUNX-NFAT Axis As a Novel Therapeutic Target for AML and T Cell Immunity

Tatsuya Masuda, Master Degree, Hirohito Kubota, MD, Naoya Sakuramoto, Master Degree, Asuka Hada, Master Degree, Ayaka Horiuchi, Master Degree, Asami Sasaki, Master Degree, Kanako Takeda, Master Degree, Mizuho Takeda, Master Degree, Hidemasa Matsuo, Hiroshi Sugiyama, PhD, Souichi Adachi, MD PhD, Yasuhiko Kamikubo
Journal: Blood
Blood (2020) 136 (Supplement 1): 25–26.
DOI: https://doi.org/10.1182/blood-2020-143458
Published: 2020
Journal Articles

KRAS mutations Frequently Coexist with High-Risk MLL Fusions and Are Independent Adverse Prognostic Factors in MLL -Rearranged Acute Myeloid Leukemia

Hidemasa Matsuo, Kenichi Yoshida, MDPhD, Kana Nakatani, Yutarou Harata, Moe Higashitani, Yuri Ito, Yasuhiko Kamikubo, Yusuke Shiozawa, MD PhD, Yuichi Shiraishi, PhD, Kenichi Chiba, Hiroko Tanaka, BA, Ai Okada, Yasuhito Nannya, MD PhD, June Takeda, MD, Hiroo Ueno, MD PhD, Nobutaka Kiyokawa, MD PhD, Daisuke Tomizawa, MD PhD, Takashi Taga, MD PhD, Akio Tawa, MD PhD, Satoru Miyano, PhD, Manja Meggendorfer, PhD, Claudia Haferlach, MD, Seishi Ogawa, MD PhD, Souichi Adachi, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 28–29.
DOI: https://doi.org/10.1182/blood-2020-134648
Published: 2020
Journal Articles

Comprehensive Genetic Analysis Revealed Myeloid/Natural Killer (NK) Cell Precursor Acute Leukemia As a Novel Distinctive Leukemia Entity

Akira Nishimura, MD, Kazuaki Yokoyama, MD PhD, Chika Yamagishi, MD, Toshihiko Imamura, MD PhD, Takuya Naruto, MD PhD, Tomohiro Morio, MD PhD, Yukie Tanaka, PhD, Akinori Kanai, PhD, Hirotaka Matsui, MD PhD, Naoko Higuchi, MD, Akiko Takada, MD, Haruna Okuno, MD, Shoji Saito, MD PhD, Shuhei Karakawa, MD PhD, Shogo Kobayashi, MD, Daisuke Hasegawa, MD PhD, Hiroyuki Fujisaki, MD PhD, Daiichiro Hasegawa, MD PhD, Kazutoshi Koike, MD PhD, Takashi Koike, MD, Shinya Rai, MD PhD, Katsutsugu Umeda, MD PhD, Hideki Sano, MD, Yujin Sekinaka, MD PhD, Atsushi Ogawa, MD PhD, Akitoshi Kinoshita, MD PhD, Norio Shiba, MD PhD, Mizuka Miki, MD, Fumihiko Kimura, MD PhD, Hideki Nakayama, MD, Yozo Nakazawa, MD PhD, Takashi Taga, MD PhD, Tomohiko Taki, MD PhD, Souichi Adachi, MD PhD, Atsushi Manabe, MD PhD, Katsuyoshi Koh, MD, Yasushi Ishida, MD PhD, Arinobu Tojo, MD PhD, Masatoshi Takagi, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 14–15.
DOI: https://doi.org/10.1182/blood-2020-139312
Published: 2020
Journal Articles

Autophagy Inhibition Enhances CDK4/6 Inhibitor-Induced Apoptosis in t(8;21) Acute Myeloid Leukemia Cells

Kana Nakatani, Hidemasa Matsuo, Yutarou Harata, Moe Higashitani, Asami Koyama, Mina Noura, Yoko Nishinaka-Arai, PhD, Yasuhiko Kamikubo, Souichi Adachi, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 50.
DOI: https://doi.org/10.1182/blood-2020-133881
Published: 2020
Journal Articles

Etoposide, Cytarabine and Mitoxantrone- or Fludarabine, Cytarabine and Granulocyte Colony-Stimulating Factor-Based Intensive Reinduction Chemotherapy Is Recommended for Children with Relapsed Acute Myeloid Leukemia: The Results from the Japanese Pediatric Leukemia/Lymphoma Study Group (JPLSG) AML-05R Study

Hiroshi Moritake, MD PhD, Shiro Tanaka, PhD, Takako Miyamura, MD PhD, Hideki Nakayama, MD, Norio Shiba, MD PhD, Akira Shimada, MDPhD, Kiminori Terui, MD PhD, Yuki Yuza, MD PhD, Katsuyoshi Koh, MD, Hiroaki Goto, MD, PhD, Harumi Kakuda, MD PhD, Akiko M Saito, MD PhD, Daisuke Hasegawa, MD PhD, Shotaro Iwamoto, MD, Takashi Taga, MD PhD, Souichi Adachi, MD PhD, Daisuke Tomizawa, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 6.
DOI: https://doi.org/10.1182/blood-2020-133272
Published: 2020
Journal Articles

Coexistence and Prognostic Significance of EVI1 Expression and Driver Mutations in KMT2A -Rearranged Acute Myeloid Leukemia

Hidemasa Matsuo, PhD, Kenichi Yoshida, MD PhD, Kana Nakatani, Yasuhiko Kamikubo, MD, PhD, Daisuke Tomizawa, MD PhD, Takashi Taga, MD PhD, Nobutaka Kiyokawa, MD PhD, Seishi Ogawa, MD PhD, Manja Meggendorfer, PhD, Claudia Haferlach, MD, Souichi Adachi, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1409.
DOI: https://doi.org/10.1182/blood-2019-124652
Published: 2019
Journal Articles

Discontinuation of Tyrosine Kinase Inhibitor in Children with Chronic Myeloid Leukemia (JPLSG STKI-14 study)

Haruko Shima, MD PhD, Akiko Kada, MPH, Akihiko Tanizawa, MD PhD, Yuki Yuza, MD PhD, Akihiro Watanabe, Masaki Ito, MD, Hideko Uryu, Katsuyoshi Koh, MD, Chihaya Imai, MD PhD, Nao Yoshida, MD PhD, Yuhki Koga, MD, Naoto Fujita, MD PhD, Akiko M Saito, MD PhD, Souichi Adachi, MD PhD, Eiichi Ishii, MD PhD, Hiroyuki Shimada, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 25.
DOI: https://doi.org/10.1182/blood-2019-122623
Published: 2019
Journal Articles

Clinical Features of Children with Polycythemia Vera, Essential Thrombocythemia, and Primary Myelofibrosis in Japan: Retrospective Nationwide Survey

Hisashi Ishida, MD PhD, Takeo Sarashina, MD PhD, Risa Matsumura, Katsutsugu Umeda, MD, PhD, Tetsuo Mitsui, MD PhD, Naoto Fujita, MD PhD, Daisuke Tomizawa, MD PhD, Kevin Y Urayama, PhD MPH, Yasushi Ishida, MD PhD, Takashi Taga, MD PhD, Masatoshi Takagi, MD PhD, Souichi Adachi, MD PhD, Atsushi Manabe, MD PhD, Toshihiko Imamura, MD PhD, Katsuyoshi Koh, MD, Akira Shimada, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2958.
DOI: https://doi.org/10.1182/blood-2019-123429
Published: 2019
Journal Articles

Therapeutic Targeting of RUNX-NFATC2 Axis for Acute Promyelocytic Leukemia and T Cell Immunity

Hirohito Kubota, MD, Kana Furuichi, Tatsuya Masuda, Toshiya Tatsuta, Hidefumi Hiramatsu, MD PhD, Junko Takita, MD PhD, Sugiyama Hiroshi, PhD, Souichi Adachi, MD PhD, Yasuhiko Kamikubo, MD, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3359.
DOI: https://doi.org/10.1182/blood-2019-126428
Published: 2019
Journal Articles

Recurrent Gene Mutations in Pediatric Patients with AML By Targeted Sequencing ―the Jccg Study, JPLSG AML-05―

Taeko Kaburagi, MD, Genki Yamato, MD PhD, Norio Shiba, Kenichi Yoshida, MD PhD, Yusuke Hara, Yuichi Shiraishi, PhD, Kentaro Ohki, MD PhD, Manabu Sotomatsu, MD PhD, Hirokazu Arakawa, MD PhD, Hidemasa Matsuo, PhD, Akira Shimada, MD PhD, Tomohiko Taki, MD PhD, Nobutaka Kiyokawa, MD PhD, Daisuke Tomizawa, MD PhD, Keizo Horibe, MD PhD, Satoru Miyano, PhD, Takashi Taga, MD PhD, Souichi Adachi, MD PhD, Seishi Ogawa, MD PhD, Yasuhide Hayashi, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2697.
DOI: https://doi.org/10.1182/blood-2019-126545
Published: 2019
Journal Articles

Clinical Features of Pediatric Acute Myeloid Leukemia with TP53 and CDKN2A / 2B copy Number Alterations

Yusuke Hara, Tomohiko Taki, MD PhD, Genki Yamato, Kenichi Yoshida, MD PhD, Yusuke Shiozawa, MD PhD, Norio Shiba, MD PhD, Taeko Kaburagi, MD, Yuichi Shiraishi, PhD, Kentaro Ohki, MD PhD, Machiko Kawamura, MD, Manabu Sotomatsu, MD PhD, Hirokazu Arakawa, MD PhD, Hidemasa Matsuo, PhD, Akira Shimada, MD PhD, Tsutomu Toki, PhD, Nobutaka Kiyokawa, MD PhD, Daisuke Tomizawa, MD PhD, Takashi Taga, MD PhD, Etsuro Ito, MD PhD, Keizo Horibe, MD PhD, Satoru Miyano, PhD, Seishi Ogawa, MD PhD, Souichi Adachi, MD PhD, Yasuhide Hayashi, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2727.
DOI: https://doi.org/10.1182/blood-2019-126263
Published: 2019
Journal Articles

Significant Features of DNA Methylation at Bivalent Promotor and Repressed Polycomb Regions in Pediatric AML-the Jccg Study, JPLSG AML-05-

Genki Yamato, Tomoko Kawai, PhD, Norio Shiba, Yusuke Hara, Kentaro Ohki, MD PhD, Taeko Kaburagi, MD, Kenichi Yoshida, MD PhD, Yuichi Shiraishi, PhD, Satoru Miyano, PhD, Nobutaka Kiyokawa, MD PhD, Daisuke Tomizawa, MD PhD, Akira Shimada, MD PhD, Manabu Sotomatsu, MD PhD, Hirokazu Arakawa, MD PhD, Souichi Adachi, MD PhD, Takashi Taga, MD PhD, Keizo Horibe, MD PhD, Seishi Ogawa, MD PhD, Kenichiro Hata, MD PhD, Yasuhide Hayashi, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2739.
DOI: https://doi.org/10.1182/blood-2019-125025
Published: 2019
Journal Articles

The Detection of Minor Clones with Somatic KIT D816V Mutations Using Droplet Digital PCR in Pediatric De Novo AML: AML-05 Trial from the Japanese Pediatric Leukemia/Lymphoma Study Group

Koji Sasaki, MD, Yuri Uchiyama, MD PhD, Junji Ikeda, Masahiro Yoshitomi, Yuko Shimosato-Wada, Mayu Tokumasu, Hidemasa Matsuo, PhD, Kenichi Yoshida, MD PhD, Kentaro Oki, MD PhD, Genki Yamato, MD PhD, Yusuke Hara, Akitoshi Kinoshita, MD, Daisuke Tomizawa, MD PhD, Takashi Taga, MD PhD, Souichi Adachi, MD PhD, Akio Tawa, MD PhD, Keizo Horibe, MD PhD, Naomichi Matsumoto, MD PhD, Shuichi Ito, MD PhD, Yasuhide Hayashi, MD PhD, Norio Shiba
Journal: Blood
Blood (2019) 134 (Supplement_1): 1419.
DOI: https://doi.org/10.1182/blood-2019-127656
Published: 2019
Journal Articles

Post-Induction Minimal Residual Disease Measured By Flow Cytometry and Deep Sequencing of Mutant GATA1 Are Both Significant Prognostic Factors for Children with Myeloid Leukemia and Down Syndrome: A Nationwide Prospective Study of the Japanese Pediatric Leukemia/Lymphoma Study Group

Takashi Taga, MD PhD, Shiro Tanaka, PhD, Kiminori Terui, MD PhD, Shotaro Iwamoto, MD, Hidefumi Hiramatsu, MD PhD, Takako Miyamura, MD PhD, Yoshiko Hashii, MD PhD, Daisuke Hasegawa, MD PhD, Hiroshi Moritake, MD PhD, Hideki Nakayama, MD, Hiroyuki Takahashi, MD PhD, Akira Shimada, MD PhD, Tomohiko Taki, MD PhD, Tsutomu Toki, PhD, Etsuro Ito, MD PhD, Katsuyoshi Koh, MD, Daiichiro Hasegawa, MD PhD, Asahito Hama, MD PhD, Akiko M Saito, MD PhD, Souichi Adachi, MD PhD, Daisuke Tomizawa, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3848.
DOI: https://doi.org/10.1182/blood-2019-123302
Published: 2019
Journal Articles

Predictive Factors of the Development of Leukemia in Patients with Transient Abnormal Myelopoiesis and Down Syndrome: The Jccg Study JPLSG TAM-10

Genki Yamato, MD PhD, Hideki Muramatsu, MD PhD, Tomoyuki Watanabe, PhD, Takao Deguchi, MD PhD, Shotaro Iwamoto, MD, Daisuke Hasegawa, MD PhD, Kiminori Terui, MD PhD, Takahiro Ueda, MD PhD, Tomoko Yokosuka, Tsutomu Toki, PhD, Shiro Tanaka, PhD, Ryu Yanagisawa, Katsuyoshi Koh, MD, Akiko M Saito, MD PhD, Keizo Horibe, MD PhD, Yasuhide Hayashi, MD PhD, Souichi Adachi, MD PhD, Shuki Mizutani, Takashi Taga, MD PhD, Etsuro Ito, MD PhD, Kenichiro Watanabe, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3833.
DOI: https://doi.org/10.1182/blood-2019-125465
Published: 2019
Journal Articles

Characterization of Pathogenic Variants and Clinical Phenotypes in 117 Japanese Fanconi Anemia Patients

Minako Mori, MD, Asuka Hira, MD PhD, Kenichi Yoshida, MD PhD, Hideki Muramatsu, MD PhD, Yusuke Okuno, MD PhD, Michiko Anmae, MS, Kazuo Tamura, MD PhD, Jun Yasuda, MD PhD, Tomoo Osumi, MD, Yasushi Noguchi, MD, Souichi Adachi, MD PhD, Hiroshi Kawabata, MD PhD, Akifumi Takaori-Kondo, MD PhD, Seiji Kojima, MD PhD, Seishi Ogawa, MD PhD, Hiromasa Yabe, MD, PhD, Miharu Yabe, MD PhD, Minoru Takata, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3860.
DOI: https://doi.org/10.1182/blood-2018-99-110362
Published: 2018