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Journal Articles

Hemopexin deficiency promotes acute kidney injury in sickle cell disease

Solomon F. Ofori-Acquah, Rimi Hazra, Oluwaseun O. Orikogbo, Danielle Crosby, Bethany Flage, Ezekiel B. Ackah, Diane Lenhart, Roderick J. Tan, Dario A. Vitturi, Vivian Paintsil, Ellis Owusu-Dabo, Samit Ghosh, in collaboration with the SickleGenAfrica Network

Blood (2020) 135 (13): 1044–1048.

https://doi.org/10.1182/blood.2019002653

Published: 2020

Includes: Supplemental data

Journal Articles

A Novel Role for P-Selectin in the Pathogenesis of Acute Chest Syndrome

Samit Ghosh, PhD, Frances Weidert, MS, Bethany Flage, BS, Prithu Sundd, PhD, Solomon F Ofori-Acquah, PhD

Blood (2016) 128 (22): 157.

https://doi.org/10.1182/blood.V128.22.157.157

Published: 2016

Journal Articles

Nrf2 Activation Attenuates Hemolysis but Promotes Pulmonary Vascular Dysfunction in Sickle Mice

Chibueze A. Ihunnah, PhD, Samit Ghosh, PhD, Scott A. Hahn, MS, Adam C Straub, PhD, Solomon F Ofori-Acquah, PhD

Blood (2016) 128 (22): 1296.

https://doi.org/10.1182/blood.V128.22.1296.1296

Published: 2016

Journal Articles

Targeted Disruption of Nrf2 in Non-Hematopoietic Tissues Exacerbates Hemolysis and Accelerates Chronic Lung Disease in Transgenic Sickle Cell Anemia Mice

Samit Ghosh, PhD, Jason Hansen, PhD, Rimi Hazra, PhD, David R. Archer, PhD, Solomon F. Ofori-Acquah, PhD

Blood (2014) 124 (21): 456.

https://doi.org/10.1182/blood.V124.21.456.456

Published: 2014

Journal Articles

Erythroid DAMPs drive inflammation in SCD

Mark T. Gladwin, Solomon F. Ofori-Acquah

Blood (2014) 123 (24): 3689–3690.

https://doi.org/10.1182/blood-2014-03-563874

Published: 2014

Journal Articles

Extracellular Hemin Auto-Amplification Intensifies Tissue Injury In Sickle Cell Disease

Samit Ghosh, PhD, Solomon F. Ofori-Acquah, PhD

Blood (2013) 122 (21): 972.

https://doi.org/10.1182/blood.V122.21.972.972

Published: 2013

Journal Articles

Targeted Treatment Of Acute Chest Syndrome In Transgenic Sickle Mice

Samit Ghosh, PhD, Olufolake Adisa, MD, Prasanthi Chappa, Fang Tan, PhD, Kesmic A Jackson, PhD, David R. Archer, PhD, Solomon F Ofori-Acquah, PhD

Blood (2013) 122 (21): 727.

https://doi.org/10.1182/blood.V122.21.727.727

Published: 2013

Journal Articles

Determinants Of Heme-Oxygenase-1 Upregulation In Patients With Sickle Cell Disease

Olufolake Adisa, MD, Benjamin Yaw Owusu, B.S., Yijuan Hu, PhD, Samit Ghosh, PhD, Fang Tan, PhD, Frederika Sey, MD, Ivy Ekem, MD, Isaac Quaye, PhD, Solomon F Ofori-Acquah, PhD

Blood (2013) 122 (21): 2235.

https://doi.org/10.1182/blood.V122.21.2235.2235

Published: 2013

Journal Articles

Heme oxygenase-1 gene promoter polymorphism is associated with reduced incidence of acute chest syndrome among children with sickle cell disease

Christopher J. Bean, Sheree L. Boulet, Dorothy Ellingsen, Meredith E. Pyle, Emily A. Barron-Casella, James F. Casella, Amanda B. Payne, Jennifer Driggers, Heidi A. Trau, Genyan Yang, Kimberly Jones, Solomon F. Ofori-Acquah, W. Craig Hooper, Michael R. DeBaun

Blood (2012) 120 (18): 3822–3828.

https://doi.org/10.1182/blood-2011-06-361642

Published: 2012

Includes: Supplemental data

Journal Articles

Heme Induced Organ Failure in Sickle Cell Disease Is Spatiotemporally Determined by the Amount of Heme Released Into the Bloodstream

Samit Ghosh, PhD, Olufolake Adisa, MD, Doreen Aryee, MD, Fang Tan, PhD, Solomon F Ofori-Acquah, PhD

Blood (2011) 118 (21): 2135.

https://doi.org/10.1182/blood.V118.21.2135.2135

Published: 2011

Journal Articles

Toll-Like Receptor 4 Mediates Heme Induced Acute Lung Injury: Preclinical Study of Resatorvid in Sickle Cell Disease

Samit Ghosh, PhD, Olufolake Adisa, MD, Yu Yang, Fang Tan, PhD, Solomon F Ofori-Acquah, PhD

Blood (2011) 118 (21): 2113.

https://doi.org/10.1182/blood.V118.21.2113.2113

Published: 2011

Journal Articles

Bone-Marrow Derived Cells Can Reconstitute GCLM Function in the Sickle Lung

Olufolake Adisa, MD, Samit Ghosh, PhD, Fang Tan, PhD, Prasanthi Chappa, David R. Archer, PhD, Solomon F Ofori-Acquah, PhD

Blood (2011) 118 (21): 4836.

https://doi.org/10.1182/blood.V118.21.4836.4836

Published: 2011

Journal Articles

Acute Chest Syndrome In Transgenic Mouse Models of Sickle Cell Disease Triggered by Free Heme

Samit Ghosh, PhD, Solomon F Ofori-Acquah, PhD

Blood (2010) 116 (21): 944.

https://doi.org/10.1182/blood.V116.21.944.944

Published: 2010

Journal Articles

Antioxidant Defense to Hemolysis Is Organ-Specific and Reflects a Heterogeneity in Vascular Permeability in Sickle Cell Disease.

Samit Ghosh, Olufolake Adisa, Fang Tan, Solomon F Ofori-Acquah

Blood (2009) 114 (22): 1537.

https://doi.org/10.1182/blood.V114.22.1537.1537

Published: 2009

Journal Articles

Cytoprotective Mechanisms of the Lung in Sickle Cell Disease.

Samit Ghosh, Fang Tan, Mario Monsunjac, Solomon F Ofori-Acquah

Blood (2009) 114 (22): 1538.

https://doi.org/10.1182/blood.V114.22.1538.1538

Published: 2009

Journal Articles

Molecular Phenotype of Sickle Chronic Lung Disease Revealed by Global Gene Expression Profiling

Fang Tan, Tianwei Yu, Yuhua Li, Samit Ghosh, Mario Mosunjac, Solomon F Ofori-Acquah

Blood (2008) 112 (11): 2480.

https://doi.org/10.1182/blood.V112.11.2480.2480

Published: 2008

Journal Articles

Essential Role for Activated Leukocyte Cell Adhesion Molecule Gene Silencing by GATA-1 in Megakaryocytic Progenitor Cell Biology.

Fang Tan, PhD, Robert Thomas, Flaubert Mbeunkui, PhD, Solomon F. Ofori-Acquah, PhD

Blood (2006) 108 (11): 1194.

https://doi.org/10.1182/blood.V108.11.1194.1194

Published: 2006

Journal Articles

Mechanisms for Transcriptional Activation of the Human Activated Leukocyte Cell Adhesion Molecule Gene and Its Silencing by Immunosuppressive Toxins.

Fang Tan, PhD, Flaubert Mbeunkui, PhD, Crystal Harris, BS, Solomon F. Ofori-Acquah, PhD

Blood (2006) 108 (11): 1637.

https://doi.org/10.1182/blood.V108.11.1637.1637

Published: 2006

Journal Articles

Mechanism for fetal hemoglobin induction by histone deacetylase inhibitors involves γ-globin activation by CREB1 and ATF-2

Jose Sangerman, Moo Seung Lee, Xiao Yao, Eugene Oteng, Cheng-Hui Hsiao, Wei Li, Sima Zein, Solomon F. Ofori-Acquah, Betty S. Pace

Blood (2006) 108 (10): 3590–3599.

https://doi.org/10.1182/blood-2006-01-023713

Published: 2006

Journal Articles

Essential Role for Activated Leukocyte Cell Adhesion Molecule in Transendothelial Migration.

Solomon F. Ofori-Acquah, PhD

Blood (2005) 106 (11): 3691.

https://doi.org/10.1182/blood.V106.11.3691.3691

Published: 2005

NARROW

Hemopexin deficiency promotes acute kidney injury in sickle cell disease

A Novel Role for P-Selectin in the Pathogenesis of Acute Chest Syndrome

Nrf2 Activation Attenuates Hemolysis but Promotes Pulmonary Vascular Dysfunction in Sickle Mice

Targeted Disruption of Nrf2 in Non-Hematopoietic Tissues Exacerbates Hemolysis and Accelerates Chronic Lung Disease in Transgenic Sickle Cell Anemia Mice

Erythroid DAMPs drive inflammation in SCD

Extracellular Hemin Auto-Amplification Intensifies Tissue Injury In Sickle Cell Disease

Targeted Treatment Of Acute Chest Syndrome In Transgenic Sickle Mice

Determinants Of Heme-Oxygenase-1 Upregulation In Patients With Sickle Cell Disease

Heme oxygenase-1 gene promoter polymorphism is associated with reduced incidence of acute chest syndrome among children with sickle cell disease

Heme Induced Organ Failure in Sickle Cell Disease Is Spatiotemporally Determined by the Amount of Heme Released Into the Bloodstream

Toll-Like Receptor 4 Mediates Heme Induced Acute Lung Injury: Preclinical Study of Resatorvid in Sickle Cell Disease

Bone-Marrow Derived Cells Can Reconstitute GCLM Function in the Sickle Lung

Acute Chest Syndrome In Transgenic Mouse Models of Sickle Cell Disease Triggered by Free Heme

Antioxidant Defense to Hemolysis Is Organ-Specific and Reflects a Heterogeneity in Vascular Permeability in Sickle Cell Disease.

Cytoprotective Mechanisms of the Lung in Sickle Cell Disease.

Molecular Phenotype of Sickle Chronic Lung Disease Revealed by Global Gene Expression Profiling

Essential Role for Activated Leukocyte Cell Adhesion Molecule Gene Silencing by GATA-1 in Megakaryocytic Progenitor Cell Biology.

Mechanisms for Transcriptional Activation of the Human Activated Leukocyte Cell Adhesion Molecule Gene and Its Silencing by Immunosuppressive Toxins.

Mechanism for fetal hemoglobin induction by histone deacetylase inhibitors involves γ-globin activation by CREB1 and ATF-2

Essential Role for Activated Leukocyte Cell Adhesion Molecule in Transendothelial Migration.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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