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Selina M. Luger
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Journal Articles

Consolidation Therapy with Blinatumomab Improves Overall Survival in Newly Diagnosed Adult Patients with B-Lineage Acute Lymphoblastic Leukemia in Measurable Residual Disease Negative Remission: Results from the ECOG-ACRIN E1910 Randomized Phase III National Cooperative Clinical Trials Network Trial

Mark R. Litzow, Zhuoxin Sun, Elisabeth Paietta, Ryan J. Mattison, Hillard M Lazarus, Jacob M. Rowe, Daniel A. Arber, Charles G. Mullighan, Cheryl L Willman, Yanming Zhang, Matthew Wieduwilt, Michaela Liedtke, Julie Bergeron, Keith W. Pratz, Shira Dinner, Noelle V. Frey, Steven D. Gore, Bhavana Bhatnagar, Ehab L. Atallah, Geoffrey L. Uy, Deepa Jeyakumar, Tara L. Lin, Richard F. Little, Selina M. Luger, Martin S. Tallman
Journal: Blood
Blood (2022) 140 (Supplement 2): LBA-1.
DOI: https://doi.org/10.1182/blood-2022-171751
Published: 2022
Journal Articles

A Phosphatase Membrane-Shuttle Enables Feedback Control of B-Cell Signaling

Jaewoong Lee, Kohei Kume, Mark E. Robinson, Ruifeng Sun, Ning Ma, Zhengshan Chen, Gang Xiao, Kadriye Nehir Cosgun, Lai N. Chan, Etienne Leveille, Lars Klemm, Vivasvan Vykunta, Brian Shy, Huimin Geng, Selina M. Luger, Mark R. Litzow, Alexander Marson, Elisabeth Paietta, Nagarajan Vaidehi, Eric Meffre, Markus Müschen
Journal: Blood
Blood (2022) 140 (Supplement 1): 1698–1699.
DOI: https://doi.org/10.1182/blood-2022-170324
Published: 2022
Journal Articles

Characteristics and Prognostic Effects of DNMT3A Co-Mutations

Alireza Torabi, Todd A. Alonzo, Megan Othus, Robert B. Gerbing, Yi-Cheng Wang, Rhonda E. Ries, Jerald P. Radich, Frederick R. Appelbaum, Kristin O'Dwyer, Harry P. Erba, Martin S. Tallman, Mark R. Litzow, Ehab L. Atallah, Selina M. Luger, Anders E. Kolb, Omar Abdel-Wahab, Derek Stirewalt, Ross L. Levine, Elisabeth Paietta, Soheil Meshinchi
Journal: Blood
Blood (2022) 140 (Supplement 1): 745–747.
DOI: https://doi.org/10.1182/blood-2022-162526
Published: 2022
Journal Articles

A Simplified Patient Care Strategy to Decrease Early Deaths in Acute Promyelocytic Leukemia (APL): Results of the ECOG-ACRIN EA9131 Trial

Anand P. Jillella, Sandra J. Lee, Jessica K. Altman, Selina M. Luger, Martin S. Tallman, James M. Foran, Lisa Y. Law, Locke J. Bryan, Abdallah Abou Zahr, Kebede Begna, Alexander Perl, Joseph Vadakara, Federico Sanchez, Raymond C. Bergan, Michael J. Fisch, Ruth C. Carlos, Lynne I. Wagner, Mark R. Litzow, Vamsi K. Kota
Journal: Blood
Blood (2022) 140 (Supplement 1): 1011–1013.
DOI: https://doi.org/10.1182/blood-2022-163436
Published: 2022
Journal Articles

Real World Effectiveness of "7 + 3" Intensive Chemotherapy Vs Venetoclax and Hypomethylating Agent for Initial Therapy in Adult Acute Myeloid Leukemia

Andrew Matthews, Alexander E. Perl, Selina M. Luger, Saar Gill, Catherine Lai, David L. Porter, Sarah Skuli, Ximena Jordan Bruno, Craig W. Freyer, Alison Carulli, Martin P. Carroll, Daria V. Babushok, Noelle V. Frey, Elizabeth O. Hexner, Mary Ellen Martin, Shannon R. McCurdy, Edward A. Stadtmauer, Alison W. Loren, Vikram R Paralkar, Ivan Maillard, Keith W. Pratz
Journal: Blood
Blood (2022) 140 (Supplement 1): 1022–1024.
DOI: https://doi.org/10.1182/blood-2022-168036
Published: 2022
Journal Articles

Novel Data Analytics Identify Predictors of Quality-of-Life Trajectories in Patients with AML or High-Risk Myeloid Neoplasms

Jordan Gauthier, Bianca Furtuna, Jacopo Mangiavacchi, Shahrzad Gholami, Juan Lavista Ferres, Rahul Dodhia, Amir T. Fathi, Andrew M. Brunner, Aaron T. Gerds, Mikkael A. Sekeres, Bruno C. Medeiros, Eunice S. Wang, Paul J Shami, Kehinde Adekola, Selina M. Luger, Maria R. Baer, David A Rizzieri, Tanya Wildes, Jamie L. Koprivnikar, Julie Smith, Mitchell A. Garrison, Kiarash Kojouri, Frederick R. Appelbaum, Mary-Elizabeth M. Percival, Stephanie J. Lee, Mohamed L. Sorror
Journal: Blood
Blood (2022) 140 (Supplement 1): 5254–5257.
DOI: https://doi.org/10.1182/blood-2022-165437
Published: 2022
Journal Articles

Patient-Reported Outcome Measures in Newly Diagnosed Acute Myeloid Leukemia: An Exploratory Analysis of Real-World Data

Xin Wang, Peter Gabriel, Abigail Doucette, Phyllis A. Gimotty, Kelly D. Getz, Samuel Takvorian, Alexander E. Perl, Shannon R. McCurdy, Selina M. Luger, Noelle V. Frey, Alison W. Loren, Elizabeth O. Hexner, Daria V. Babushok, David L. Porter, Keith W. Pratz, Catherine Lai
Journal: Blood
Blood (2022) 140 (Supplement 1): 13287–13288.
DOI: https://doi.org/10.1182/blood-2022-170733
Published: 2022
Journal Articles

Fried's Frailty Phenotype Predicts Mortality and Survival for Newly Diagnosed Older Patients with Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Cristian C. Taborda, Shannon H Gier, Avery W Stivale, Alexander E. Perl, Saar Gill, Daria V. Babushok, Elizabeth O. Hexner, Noelle V. Frey, Catherine Lai, Ximena Jordan Bruno, Mary Ellen Martin, Ivan Maillard, David L. Porter, Alison W. Loren, Keith W. Pratz, Selina M. Luger, Phyllis A. Gimotty, Shannon R. McCurdy
Journal: Blood
Blood (2022) 140 (Supplement 1): 10825–10827.
DOI: https://doi.org/10.1182/blood-2022-169924
Published: 2022
Journal Articles

Umbrella Trial in Myeloid Malignancies: The Myelomatch National Clinical Trials Network Precision Medicine Initiative

Richard F. Little, Megan Othus, Sarit Assouline, Sherry Ansher, Ehab L. Atallah, R. Coleman Lindsley, Boris Freidlin, Steven D. Gore, Lyndsay Harris, Christopher S. Hourigan, S. Percy Ivy, Shahanawaz Jiwani, Erin Langan, Selina M. Luger, Laura C. Michaelis, Olatoyosi Odenike, David Patton, Miguel-Angel Perales, Jerald P. Radich, Bhanu Ramineni, Jesse J. Salk, Patrick Stiff, Wendy Stock, Richard M. Stone, Geoffrey L. Uy, P. Mickey Williams, Brent L. Wood, Katherine H Worthington, Laura M Yee, Amer M. Zeidan, Jianqiao Zhang, Mark R. Litzow, Harry P. Erba
Journal: Blood
Blood (2022) 140 (Supplement 1): 9057–9060.
DOI: https://doi.org/10.1182/blood-2022-169307
Published: 2022
Journal Articles

Enhancer retargeting of CDX2 and UBTF::ATXN7L3 define a subtype of high-risk B-progenitor acute lymphoblastic leukemia

Shunsuke Kimura, Lindsey Montefiori, Ilaria Iacobucci, Yaqi Zhao, Qingsong Gao, Elisabeth M. Paietta, Claudia Haferlach, A. Douglas Laird, Paul E. Mead, Zhaohui Gu, Wendy Stock, Mark Litzow, Jacob M. Rowe, Selina M. Luger, Stephen P. Hunger, Georgina L. Ryland, Breon Schmidt, Paul G. Ekert, Alicia Oshlack, Sean M. Grimmond, Jacqueline Rehn, James Breen, David Yeung, Deborah L. White, Ibrahim Aldoss, Elias J. Jabbour, Ching-Hon Pui, Manja Meggendorfer, Wencke Walter, Wolfgang Kern, Torsten Haferlach, Samuel Brady, Jinghui Zhang, Kathryn G. Roberts, Piers Blombery, Charles G. Mullighan
Journal: Blood
Blood (2022) 139 (24): 3519–3531.
DOI: https://doi.org/10.1182/blood.2022015444
Published: 2022
Includes: Supplemental data
Journal Articles

Minimal Toxicity Seen When Pembrolizumab Is Added to Tyrosine Kinase Inhibitors in Patients with Chronic Myeloid Leukemia and Persistently Detectable Minimal Residual Disease: Early Results from an Ongoing Phase II Trial (ECOG-ACRIN EA9171)

Amer M. Zeidan, Kevin Roopcharan, Jerry P. Radich, Jan Philipp Bewersdorf, Vijaya R. Bhatt, Elad Sharon, Richard F. Little, Steven D. Gore, Anne Caldwell, Selina M. Luger, Mark R. Litzow
Journal: Blood
Blood (2021) 138 (Supplement 1): 3613.
DOI: https://doi.org/10.1182/blood-2021-145015
Published: 2021
Journal Articles

Real World Survival Outcomes of CPX-351 Versus Venetoclax and Azacitadine for Initial Therapy in Adult Acute Myeloid Leukemia

Andrew Matthews, Alexander E. Perl, Selina M. Luger, Daria V. Babushok, Noelle V Frey, Saar Gill, Elizabeth O. Hexner, Mary Ellen Martin, Shannon R. McCurdy, David L. Porter, Edward A. Stadtmauer, Alison W. Loren, Vikram R Paralkar, Ivan Maillard, David Margolis, Keith W. Pratz
Journal: Blood
Blood (2021) 138 (Supplement 1): 795.
DOI: https://doi.org/10.1182/blood-2021-149158
Published: 2021
Journal Articles

Mutational Landscape of MDS Patients with HMA Failure Revealed By the Correlative Analysis from Inspire Trial

Koichi Takahashi, Anna Jonasova, Selina M. Luger, Aref Al-Kali, David Valcarcel, Erica D. Warlick, Maria Diez-Campelo, Michael K Keng, Feng Wang, Ken Furudate, Patrick S. Zbyszewski, Matthew Parris, Steven M. Fruchtman, Guillermo Garcia-Manero
Journal: Blood
Blood (2021) 138 (Supplement 1): 1517.
DOI: https://doi.org/10.1182/blood-2021-152048
Published: 2021
Journal Articles

Allogeneic Transplantation in Fit Older Adults Is Feasible and Encouragingly Efficacious. Post Remission Data from the Prospective ECOG-ACRIN (E2906) Clinical Study

Yishai Ofran, Zhuoxin Sun, Jacob M. Rowe, David F. Claxton, Martin S. Tallman, Daniel A. Arber, Ari Melnick, Ross L. Levine, Elisabeth Paietta, John E. Godwin, Hillard M Lazarus, Selina M. Luger, James M. Foran, Mark R. Litzow
Journal: Blood
Blood (2021) 138 (Supplement 1): 413.
DOI: https://doi.org/10.1182/blood-2021-149356
Published: 2021
Journal Articles

A Phase 1 Study of XmAb18968, a CD3-CD38 Bispecific Antibody for the Treatment of Patients with Relapsed/Refractory Acute Leukemia and T Cell Lymphoblastic Lymphoma

Guru Subramanian Guru Murthy, Tyce J Kearl, Weiguo Cui, Bryon Johnson, Karin Hoffmeister, Aniko Szabo, Kazuhiro Aoki, Alexandra M. Harrington, Karen Carlson, Laura C. Michaelis, Lyndsey Runaas, Sameem Abedin, Adam S Duvall, Wendy Stock, Bijal D. Shah, Jessica Leonard, Keith W. Pratz, Selina M. Luger, Talha Badar, Arielle Baim, Shahriar Yaghoubi, Ehab L. Atallah
Journal: Blood
Blood (2021) 138 (Supplement 1): 4401.
DOI: https://doi.org/10.1182/blood-2021-149329
Published: 2021
Journal Articles

Aspacytarabine (BST-236) As Monotherapy Is Safe, Well-Tolerated and Effective for the Treatment of Adults with Newly Diagnosed Acute Myeloid Leukemia Unfit for Intensive Therapy. Results of a Phase 2 Study

Jessica K. Altman, Jamie Koprivnikar, James K McCloskey, Vamsi Kota, Michael Keng, Dale L. Bixby, Olga Frankfurt, Ashkan Emadi, Tsila Zuckerman, Micah M. Burch, Moshe Y. Levy, Selina M. Luger, Bhavana Bhatnagar, Ofir Wolach, Chezi Ganzel, Mary-Beth M. Percival, Gail J. Roboz, Michael Craig, Itai Levi, Anna Gourevitch, Liat Flaishon, Darrel P. Cohen, Shoshi Tessler, Chen Blumberg, Stela Gengrinovitch, Ruth Ben Yakar, Jacob M. Rowe
Journal: Blood
Blood (2021) 138 (Supplement 1): 1273.
DOI: https://doi.org/10.1182/blood-2021-149361
Published: 2021
Journal Articles

Incidence and Predictors of Sars-Cov-2 Antibody Responses Following COVID-19 Vaccination in Allogeneic Stem Cell Transplant Recipients

Janna C. Minehart, Christopher Catania, Linda Perry, Mary Ellen Martin, Jacqueline Smith, Shannon R. McCurdy, Keith W. Pratz, Selina M. Luger, Colleen Timlin, Alexander E. Perl, Mindy Schuster, David L Porter, Alison W. Loren, Elizabeth O. Hexner, Noelle V Frey
Journal: Blood
Blood (2021) 138 (Supplement 1): 2888.
DOI: https://doi.org/10.1182/blood-2021-153920
Published: 2021
Journal Articles

Enrollment Characteristics and Outcomes of Hispanic and Black AYA ALL Patients Enrolled on a U.S. Intergroup Clinical Trial: A Comparison of the CALGB 10403 (Alliance) Cohort with U.S. Population-Level Data

Lori Muffly, Jun Yin, Sawyer Jacobson, Anjali Advani, Selina M. Luger, Martin S. Tallman, Mark R. Litzow, Matthew C. Foster, Frederick R. Appelbaum, Richard A. Larson, Theresa Keegan, Wendy Stock
Journal: Blood
Blood (2021) 138 (Supplement 1): 337.
DOI: https://doi.org/10.1182/blood-2021-148804
Published: 2021
Journal Articles

Maximal Tolerated Dose Determined for Venetoclax in Combination with Liposomal Vincristine in Patients with Relapsed or Refractory Ph-Negative T-Cell or B-Cell Acute Lymphoblastic Leukemia: Results of Phase 1 Portion of ECOG-ACRIN EA9152

Neil Palmisiano, Ju-Whei Lee, David F. Claxton, Elisabeth Paietta, Hassan B. Alkhateeb, Jae H Park, Nikolai Podoltsev, Ehab L. Atallah, Dale G Schaar, Shira Dinner, Jonathan Webster, Selina M. Luger, Mark R. Litzow
Journal: Blood
Blood (2021) 138 (Supplement 1): 3407.
DOI: https://doi.org/10.1182/blood-2021-153621
Published: 2021
Journal Articles

CART22-65s Co-Administered with huCART19 in Adult Patients with Relapsed or Refractory ALL

Noelle V Frey, Saar Gill, Wei-Ting Hwang, Selina M. Luger, Mary Ellen Martin, Shannon R. McCurdy, Alison W. Loren, Keith W. Pratz, Alexander E. Perl, Julie Barber-Rotenberg, Amy Marshall, Marco Ruella, Simon F Lacey, Joseph Fraietta, Andrew Fesnak, Megan O'brien, Theresa Schanne, Jennifer L Brogdon, Boris Engels, Bruce L Levine, Carl H June, David L Porter, Elizabeth O. Hexner
Journal: Blood
Blood (2021) 138 (Supplement 1): 469.
DOI: https://doi.org/10.1182/blood-2021-153955
Published: 2021