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Sameer A. Parikh
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Journal Articles

CD19 occupancy with tafasitamab increases therapeutic index of CART19 cell therapy and diminishes severity of CRS

R. Leo Sakemura, Claudia Manriquez Roman, Paulina Horvei, Elizabeth L. Siegler, James H. Girsch, Olivia L. Sirpilla, Carli M. Stewart, Kun Yun, Ismail Can, Ekene J. Ogbodo, Mohamad M. Adada, Evandro Bezerra, Lionel Aurelien Kankeu Fonkoua, Mehrdad Hefazi, Michael W Ruff, Brooke L Kimball, Long K Mai, Truc N. Huynh, Wendy Nevala, Kristina Ilieva, Christian Augsberger, Maria Patra-Kneuer, Jürgen Schanzer, Jan Endell, Christina Heitmüller, Stefan Steidl, Sameer A Parikh, Wei Ding, Neil E. Kay, Grzegorz S. Nowakowski, Saad S. Kenderian
Journal: Blood
Blood blood.2022018905.
https://doi.org/10.1182/blood.2022018905
Published: 2023
Includes: Supplemental data
Journal Articles

Chronic Lymphocytic Leukemia in African Ancestry Population Is Characterized By Increased Telomere Erosion

Cecilia Bonolo De Campos, Chantal McCabe, Laura Ann Bruins, Daniel R. O'Brien, Sochilt Brown, Cristine Allmer, Yuan Xiao Zhu, Kari G Rabe, Sameer A. Parikh, Neil E. Kay, James R. Cerhan, Laura Z Rassenti, Richard R. Furman, J. Brice Weinberg, Danielle Brander, Marta Chesi, Susan L. Slager, Esteban Braggio
Journal: Blood
Blood (2022) 140 (Supplement 1): 4135–4136.
https://doi.org/10.1182/blood-2022-170944
Published: 2022
Journal Articles

Efficacy and Safety of Nemtabrutinib, a Wild-Type and C481S-Mutated Bruton Tyrosine Kinase Inhibitor for B-Cell Malignancies: Updated Analysis of the Open-Label Phase 1/2 Dose-Expansion Bellwave-001 Study

Jennifer A. Woyach, Ian W. Flinn, Farrukh T. Awan, Herbert Eradat, Danielle Brander, Michael Tees, Sameer A. Parikh, Tycel J. Phillips, Razi Ghori, Nishitha M. Reddy, Mohammed Z.H. Farooqui, John C. Byrd, Deborah M. Stephens
Journal: Blood
Blood (2022) 140 (Supplement 1): 7004–7006.
https://doi.org/10.1182/blood-2022-163596
Published: 2022
Journal Articles

Treatment Patterns and Outcomes of Patients with Chronic Lymphocytic Leukemia with TP53 Mutations

Steven R Hwang, Yucai Wang, Kari G Rabe, Rong He, Saad S. Kenderian, Eli Muchtar, Paul J. Hampel, Neil E. Kay, Timothy G. Call, Amber Koehler, Amy L Behnken, Jose F. Leis, Esteban Braggio, Min Shi, David S. Viswanatha, Daniel L. Van Dyke, Susan L. Slager, Sameer A. Parikh, Wei Ding
Journal: Blood
Blood (2022) 140 (Supplement 1): 12390–12392.
https://doi.org/10.1182/blood-2022-165508
Published: 2022
Journal Articles

Evolutionary History of Transformation from Chronic Lymphocytic Leukemia to Richter Syndrome

Erin Michelle Parry, Romain Guieze, Ignaty Leshchiner, Connor Johnson, Eugen Tausch, Sameer A. Parikh, Camilla K Lemvigh, Julien Broséus, Sébastien Hergalant, Connor Messer, Filippo Utro, Chaya Levovitz, Kahn Rhrissorrakrai, Liang Li, Shuqiang Li, Geoffrey G Fell, Robert A. Redd, Ziao Lin, Binyamin A. Knisbacher, Christof Schneider, Stacey M. Fernandes, Julian M. Hess, Laura Z. Rassenti, Thomas J. Kipps, Nitin Jain, William G. Wierda, Florence Cymbalista, Pierre Feugier, Neil E. Kay, Kenneth J Livak, Brian P Danysh, Chip Stewart, Donna S. Neuberg, Matthew S. Davids, Jennifer R. Brown, Laxmi Parida, Stephan Stilgenbauer, Gad Getz, Catherine J. Wu
Journal: Blood
Blood (2022) 140 (Supplement 1): 1530–1533.
https://doi.org/10.1182/blood-2022-160335
Published: 2022
Journal Articles

CD19 Antigen Occupancy on Cancer Cells with the CD19 Monoclonal Antibody Tafasitamab Improves the Activation, Antitumor Efficacy, and Safety Profile of CART19 Cell Therapy

Reona Leo Sakemura, Claudia Manriquez-Roman, Paulina Horvei, Michelle J. Cox, Truc Huynh, James H. Girsch, Olivia Sirpilla, Kun Yun, Carli M. Stewart, Ismail Can, Ekene J. Ogbodo, Mohamad M. Adada, Lionel A. Kankeu Fonkoua, Mehrdad Hefazi, Michael W. Ruff, Kristina Ilieva-Babinsky, Christian Augsberger, Maria Patra-Kneuer, Christina Heitmüller, Stefan Steidl, Sameer A. Parikh, Wei Ding, Neil E. Kay, Grzegorz S. Nowakowski, Elizabeth L. Siegler, Saad S. Kenderian
Journal: Blood
Blood (2022) 140 (Supplement 1): 2362–2364.
https://doi.org/10.1182/blood-2022-158273
Published: 2022
Journal Articles

An Ex Vivo Monocyte Stimulation Test Predicts Severity of COVID-19 Infection in Patients with Chronic Lymphocytic Leukemia (CLL)

Gordon Ruan, Xiaosheng Wu, Kimberly Gwin, Michelle K. Manske, Jithma P. Abeykoon, Taylor L. Witter, Matthew J. Schellenberg, Kari G Rabe, Sara J. Achenbach, Neil E. Kay, Sameer A. Parikh, Thomas E. Witzig
Journal: Blood
Blood (2022) 140 (Supplement 1): 8314–8315.
https://doi.org/10.1182/blood-2022-156815
Published: 2022
Journal Articles

Comparison of Treatment-Emergent Adverse Events of Covalent BTK Inhibitors in Clinical Trials in B-Cell Malignancies: A Systematic Review and Meta-Analysis

Jacqueline F Wang, Steven R Hwang, Yi Jiang, Xinyue Qi, Shijia Zhang, Sameer A. Parikh, Wei Ding, Saad S. Kenderian, Eli Muchtar, Paul J. Hampel, Jose F. Leis, Javier L Munoz, Gita Thanarajasingam, Jonas Paludo, David J. Inwards, Grzegorz S. Nowakowski, Stephen M. Ansell, Thomas M. Habermann, Thomas E. Witzig, Neil E. Kay, Shouhao Zhou, Yucai Wang
Journal: Blood
Blood (2022) 140 (Supplement 1): 9882–9884.
https://doi.org/10.1182/blood-2022-168152
Published: 2022
Journal Articles

Differences in Humoral and Cellular Response to COVID-19 Vaccine Against Different Variants over Time in Chronic Lymphocytic Leukemia

Matteo Passerini, Tamar Ratishvili, Neil E. Kay, Zelalem Temesgen, Thomas E. Witzig, Richard Kennedy, Sameer A. Parikh
Journal: Blood
Blood (2022) 140 (Supplement 1): 13092–13094.
https://doi.org/10.1182/blood-2022-159543
Published: 2022
Journal Articles

Progression and survival of MBL: a screening study of 10 139 individuals

Susan L. Slager, Sameer A. Parikh, Sara J. Achenbach, Aaron D. Norman, Kari G. Rabe, Nicholas J. Boddicker, Janet E. Olson, Geffen Kleinstern, Connie E. Lesnick, Timothy G. Call, James R. Cerhan, Celine M. Vachon, Neil E. Kay, Esteban Braggio, Curtis A. Hanson, Tait D. Shanafelt
Journal: Blood
Blood (2022) 140 (15): 1702–1709.
https://doi.org/10.1182/blood.2022016279
Published: 2022
Includes: Supplemental data
Journal Articles

Targeting cancer-associated fibroblasts in the bone marrow prevents resistance to CART-cell therapy in multiple myeloma

Reona Sakemura, Mehrdad Hefazi, Elizabeth L. Siegler, Michelle J. Cox, Daniel P. Larson, Michael J. Hansen, Claudia Manriquez Roman, Kendall J. Schick, Ismail Can, Erin E. Tapper, Paulina Horvei, Mohamad M. Adada, Evandro D. Bezerra, Lionel Aurelien Kankeu Fonkoua, Michael W. Ruff, Wendy K. Nevala, Denise K. Walters, Sameer A. Parikh, Yi Lin, Diane F. Jelinek, Neil E. Kay, P. Leif Bergsagel, Saad S. Kenderian
Journal: Blood
Blood (2022) 139 (26): 3708–3721.
https://doi.org/10.1182/blood.2021012811
Published: 2022
Includes: Supplemental data
Journal Articles

B Cell Receptor Signaling Drives APOBEC3 Expression Via Direct Enhancer Regulation in Chronic Lymphocytic Leukemia B Cells

Zhiquan Wang, Huihuang Yan, Justin C. Boysen, Charla R. Secreto, Esteban Braggio, Susan L. Slager, Sameer A. Parikh, Neil E. Kay
Journal: Blood
Blood (2021) 138 (Supplement 1): 3313.
https://doi.org/10.1182/blood-2021-153214
Published: 2021
Journal Articles

Relationship and Susceptibility to Serious Infections Among Monoclonal B-Cell Lymphocytosis (MBL), Monoclonal Gammopathy of Undetermined Significance (MGUS), and Clonal Hematopoiesis (CH) Premalignant Conditions

Nicholas J. Boddicker, Sameer A. Parikh, Geffen Kleinstern, Aaron D. Norman, Kari G. Rabe, Timothy G. Call, Janet E. Olson, Angela Dispenzieri, David L Murray, S. Vincent Rajkumar, Shaji Kumar, James R. Cerhan, Neil E. Kay, Esteban Braggio, Curtis A. Hanson, Tait Shanafelt, Celine M. Vachon, Susan L. Slager
Journal: Blood
Blood (2021) 138 (Supplement 1): 3739.
https://doi.org/10.1182/blood-2021-151929
Published: 2021
Journal Articles

The Impact of Prior Treatment with a CD19 Targeting Monoclonal Antibody on Subsequent Treatment with CD19 Targeting CART Cell Therapy in Preclinical Models

Reona Sakemura, Paulina Horvei, Claudia Manriquez-Roman, Ekene J. Ogbodo, Erin E. Tapper, Elizabeth L. Siegler, Carli M. Stewart, Kendall J. Schick, Ismail Can, Mohamad M. Adada, Evandro D. Bezerra, Lionel A. Kankeu Fonkoua, Mehrdad Hefazi, Michael W. Ruff, Christian Augsberger, Juergen Schanzer, Maria Patra-Kneuer, Christina Heitmüller, Stefan Steidl, Jan Endell, Wei Ding, Sameer A. Parikh, Susan L. Slager, Neil E. Kay, Grzegorz S. Nowakowski, Michelle J. Cox, Saad S. Kenderian
Journal: Blood
Blood (2021) 138 (Supplement 1): 2412.
https://doi.org/10.1182/blood-2021-145649
Published: 2021
Journal Articles

Prevalence and Overall Survival of Low Count Monoclonal B-Cell Lymphocytosis (LC-MBL): A Screening Study of 8,297 Individuals from the Mayo Clinic Biobank

Susan L. Slager, Sameer A. Parikh, Sara J. Achenbach, Geffen Kleinstern, Nicholas J. Boddicker, Aaron D. Norman, Kari G. Rabe, Connie E. Lesnick, Timothy G. Call, Janet E. Olson, James R. Cerhan, Neil E. Kay, Celine M. Vachon, Esteban Braggio, Curtis A. Hanson, Tait Shanafelt
Journal: Blood
Blood (2021) 138 (Supplement 1): 2632.
https://doi.org/10.1182/blood-2021-153320
Published: 2021
Journal Articles

TP53 Aberrations and Outcomes in MBL and Untreated CLL

Rosalie Griffin Waller, Julia E. Wiedmeier, Nicholas J. Boddicker, Geffen Kleinstern, Cecilia Bonolo De Campos, Daniel L. Van Dyke, Huihuang Yan, Celine M. Vachon, Daniel R. O'Brien, Cristine Allmer, Kari G. Rabe, James R. Cerhan, Timothy G. Call, Sameer A. Parikh, Neil E. Kay, Esteban Braggio, Susan L. Slager
Journal: Blood
Blood (2021) 138 (Supplement 1): 2618.
https://doi.org/10.1182/blood-2021-153602
Published: 2021
Journal Articles

Utilization of a Targeted Next Generation Sequencing Assay to Identify Copy Number Alterations in Chronic Lymphocytic Leukemia and Monoclonal B-Cell Lymphocytosis

Julia E. Wiedmeier, Chantal McCabe, Daniel R. O'Brien, Nicholas J. Boddicker, Rosalie Griffin Waller, Cecilia Bonolo De Campos, James R. Cerhan, Sameer A. Parikh, Neil E. Kay, Huihuang Yan, Daniel L. Van Dyke, Susan L. Slager, Esteban Braggio
Journal: Blood
Blood (2021) 138 (Supplement 1): 4677.
https://doi.org/10.1182/blood-2021-153001
Published: 2021
Journal Articles

Favorable Modulation of Chimeric Antigen Receptor T Cells Safety and Efficacy By the Non-Covalent BTK Inhibitor Vecabrutinib

Mohamad M. Adada, Reona Sakemura, Michelle J. Cox, Caludia Manriquez-Roman, Elizabeth L. Siegler, Erin E. Tapper, Carli M. Stewart, Kendall J. Schick, Ismail Can, Ekene J. Ogbodo, Evandro D. Bezerra, Lionel A. Kankeu Fonkoua, Mehrdad Hefazi, Michael W. Ruff, Pietro Taverna, Judith A. Fox, Gloria Olivier, Susan L. Slager, Wei Ding, Sameer A. Parikh, Neil E. Kay, Saad S. Kenderian
Journal: Blood
Blood (2021) 138 (Supplement 1): 906.
https://doi.org/10.1182/blood-2021-151073
Published: 2021
Journal Articles

Optimized Inhibition of GM-CSF in Preclinical Models of Anti-CD19 Chimeric Antigen Receptor T Cell Therapy

Evandro D. Bezerra, Reona Sakemura, James Girsch, Carli M. Stewart, Gunjan A Awatramani, Claudia Manriquez-Roman, Kendall J. Schick, Ismail Can, Ekene J. Ogbodo, Erin E. Tapper, Elizabeth L. Siegler, Mohamad M. Adada, Lionel A. Kankeu Fonkoua, Mehrdad Hefazi, Michael W. Ruff, Susan L. Slager, Sameer A. Parikh, Neil E. Kay, Cameron Durrant, Omar Ahmed, Dale Chappell, Michelle J. Cox, Saad S. Kenderian
Journal: Blood
Blood (2021) 138 (Supplement 1): 2777.
https://doi.org/10.1182/blood-2021-149859
Published: 2021
Journal Articles

TNFR2 As a Target to Improve CD19-Directed CART Cell Fitness and Antitumor Activity in Large B Cell Lymphoma

Claudia Manriquez Roman, Michelle J. Cox, Reona Sakemura, Kun Yun, Mohamad M. Adada, Elizabeth L. Siegler, Olivia Sirpilla, Erin E. Tapper, Carli M. Stewart, Ekene J. Ogbodo, Ismail Can, Kendall J. Schick, Evandro D. Bezerra, Lionel A. Kankeu Fonkoua, Mehrdad Hefazi, Michael W. Ruff, Wei Ding, Sameer A. Parikh, Susan L. Slager, Neil E. Kay, Gloria Olivier, Nathalie Scholler, Adrian Bot, Mike Mattie, Jenny J. Kim, Simone Filosto, Saad S. Kenderian
Journal: Blood
Blood (2021) 138 (Supplement 1): 901.
https://doi.org/10.1182/blood-2021-148591
Published: 2021