Search Results | Blood | American Society of Hematology

1-20 of 62

2 3 4

Sort by

Sort Order Select

Journal Articles

Immune Complications and their Management in Inherited and Acquired Bleeding Disorders

Valder R Arruda, David Lillicrap, Roland W Herzog

Blood blood.2022016530.

DOI: https://doi.org/10.1182/blood.2022016530

Published: 2022

Journal Articles

Factor IX Delivery to the Skin Primes Inhibitor Formation and Sensitizes Hemophilia B Mice to Systemic Factor IX Administration

Radoslaw Kaczmarek, Thais Bertolini, Roland W Herzog, Alexandra Sherman

Blood (2021) 138 (Supplement 1): 3194.

DOI: https://doi.org/10.1182/blood-2021-154146

Published: 2021

Journal Articles

Helper T Cell Response to Factor VIII In Vivo Requires Several Anatomically Distinct Types of Antigen Presenting Cells

Radoslaw Kaczmarek, Annie R Pineros, Matthew Carl Arvin, Thais Bertolini, Rodney M. Camire, Roland W Herzog

Blood (2021) 138 (Supplement 1): 440.

DOI: https://doi.org/10.1182/blood-2021-146059

Published: 2021

Journal Articles

Cross Priming of Transgene Product-Specific CD8 + T Cells in Hepatic AAV Gene Transfer Depends on IL-1 Receptor and XCR1 + Dendritic Cells but Not TLR9

Sandeep Kumar, PhD, Moanaro Biswas, PhD, Annie R Pineros, PhD, Ype P De Jong, MD, Roland W Herzog, PhD

Blood (2020) 136 (Supplement 1): 2–3.

DOI: https://doi.org/10.1182/blood-2020-142926

Published: 2020

Journal Articles

AAV Vector Dose Determines TLR9 Dependence of CD8+ T Cell Response to Transgene Product

Ning Li, Thais Bertolini, Roland W Herzog, PhD

Blood (2020) 136 (Supplement 1): 3.

DOI: https://doi.org/10.1182/blood-2020-141054

Published: 2020

Journal Articles

Revisiting the "Danger Theory": Toll-like Receptor 9 Stimulation Triggers Activation of Conventional CD8α + and Plasmacytoid Dendritic Cells En Route to Enhancing FVIII Inhibitor Formation

Radoslaw Kaczmarek, PhD, Thais Bertolini, Roland W Herzog, PhD

Blood (2020) 136 (Supplement 1): 1.

DOI: https://doi.org/10.1182/blood-2020-143259

Published: 2020

Journal Articles

Alternative Approaches to Oral Tolerance Induction to Factor FVIII

Thais Bertolini, Moanaro Biswas, PhD, Radoslaw Kaczmarek, PhD, Henry Daniell, PhD, Roland W Herzog, PhD

Blood (2020) 136 (Supplement 1): 8–9.

DOI: https://doi.org/10.1182/blood-2020-142661

Published: 2020

Journal Articles

Toll-like Receptor 9 Activation Accelerates Inhibitor Formation in Response to Factor VIII

Radoslaw Kaczmarek, Alexandra Sherman, DVM, Moanaro Biswas, PhD, Roland W Herzog, PhD

Blood (2019) 134 (Supplement_1): 1113.

DOI: https://doi.org/10.1182/blood-2019-125348

Published: 2019

Journal Articles

Update on clinical gene therapy for hemophilia

George Q. Perrin, Roland W. Herzog, David M. Markusic

Blood (2019) 133 (5): 407–414.

DOI: https://doi.org/10.1182/blood-2018-07-820720

Published: 2019

Journal Articles

Reprogrammed CD4 + T Cells That Express FoxP3 + Effectively Control Inhibitory Antibody Development in Hemophilic Mice

Moanaro Biswas, PhD, Veronica Kuteyeva, Roland W Herzog, PhD

Blood (2017) 130 (Supplement 1): 175.

DOI: https://doi.org/10.1182/blood.V130.Suppl_1.175.175

Published: 2017

Journal Articles

Generation of FVIII-Specific Tregs Expressing a Chimeric Antigen Receptor (CAR) to Suppress Inhibitor Development in Hemophilia a Mice

Moanaro Biswas, PhD, Todd M Brusko, PhD, Roland W Herzog, PhD

Blood (2017) 130 (Supplement 1): 176.

DOI: https://doi.org/10.1182/blood.V130.Suppl_1.176.176

Published: 2017

Journal Articles

Innate Immune Activation Via TLR9 May Enhance Antibody Formation Against Factors VIII and IX in Protein and Gene Therapy

Roland W Herzog, PhD, Alexandra Sherman, DVM, Brad E. Hoffman, PhD

Blood (2017) 130 (Supplement 1): 3651.

DOI: https://doi.org/10.1182/blood.V130.Suppl_1.3651.3651

Published: 2017

Journal Articles

Lettuce Plants Expressing High Levels of Factor VIII Antigen in the Chloroplast for Oral Tolerance in Hemophilia a

Roland W Herzog, PhD, Alexandra Sherman, DVM, Kwang-Chul Kwon, PhD, Wan-Jung Chang, MS, Henry Daniell, PhD

Blood (2017) 130 (Supplement 1): 362.

DOI: https://doi.org/10.1182/blood.V130.Suppl_1.362.362

Published: 2017

Journal Articles

Plasmacytoid and conventional dendritic cells cooperate in crosspriming AAV capsid-specific CD8 + T cells

Geoffrey L. Rogers, Jamie L. Shirley, Irene Zolotukhin, Sandeep R. P. Kumar, Alexandra Sherman, George Q. Perrin, Brad E. Hoffman, Arun Srivastava, Etiena Basner-Tschakarjan, Mark A. Wallet, Cox Terhorst, Moanaro Biswas, Roland W. Herzog

Blood (2017) 129 (24): 3184–3195.

DOI: https://doi.org/10.1182/blood-2016-11-751040

Published: 2017

Includes: Supplemental data

Journal Articles

Driving the hemophilia tolerance CAR

Roland W. Herzog

Blood (2017) 129 (2): 142–144.

DOI: https://doi.org/10.1182/blood-2016-11-753160

Published: 2017

Journal Articles

Hepatic AAV Gene Transfer of Cytoplasmic Transgene Induces Transgene Product-Specific T Cell Activation Initially in the Liver and Celiac Lymph Node Preceding Treg Induction

Roland W. Herzog, PhD, George Q. Perrin, PhD

Blood (2015) 126 (23): 3241.

DOI: https://doi.org/10.1182/blood.V126.23.3241.3241

Published: 2015

Journal Articles

AAV3 Capsid Is Superior for In Vivo Gene Transfer to Human Hepatocytes Compared to Serotypes 5 and 8 in a Mouse/Human Chimeric Model

Roland W. Herzog, PhD, Brad E. Hoffman, PhD, Irene Zolotukhin, MS, Katherine A. High, MD, Arun Srivastava, PhD, Ype P. de Jong, MD PhD, Koen Vercauteren, PhD, Jing Xiao

Blood (2015) 126 (23): 4418.

DOI: https://doi.org/10.1182/blood.V126.23.4418.4418

Published: 2015

Journal Articles

Factor IX Expressed in Lettuce Chloroplasts Induces Oral Tolerance in Hemophilia B Mice

Roland W. Herzog, PhD, Jin Su, PhD, Liqing Zhu, BS, Xiaomei Wang, PhD, Shina Lin, BS, Aditya Kamesh, BS, Henry Daniell, PhD

Blood (2015) 126 (23): 292.

DOI: https://doi.org/10.1182/blood.V126.23.292.292

Published: 2015

Journal Articles

Synergy between rapamycin and FLT3 ligand enhances plasmacytoid dendritic cell–dependent induction of CD4 + CD25 + FoxP3 + Treg

Moanaro Biswas, Debalina Sarkar, Sandeep R. P. Kumar, Sushrusha Nayak, Geoffrey L. Rogers, David M. Markusic, Gongxian Liao, Cox Terhorst, Roland W. Herzog

Blood (2015) 125 (19): 2937–2947.

DOI: https://doi.org/10.1182/blood-2014-09-599266

Published: 2015

Includes: Supplemental data

Journal Articles

Plant-based oral tolerance to hemophilia therapy employs a complex immune regulatory response including LAP + CD4 + T cells

Xiaomei Wang, Jin Su, Alexandra Sherman, Geoffrey L. Rogers, Gongxian Liao, Brad E. Hoffman, Kam W. Leong, Cox Terhorst, Henry Daniell, Roland W. Herzog

Blood (2015) 125 (15): 2418–2427.

DOI: https://doi.org/10.1182/blood-2014-08-597070

Published: 2015

Includes: Supplemental data

2 3 4

NARROW

Immune Complications and their Management in Inherited and Acquired Bleeding Disorders

Factor IX Delivery to the Skin Primes Inhibitor Formation and Sensitizes Hemophilia B Mice to Systemic Factor IX Administration

Helper T Cell Response to Factor VIII In Vivo Requires Several Anatomically Distinct Types of Antigen Presenting Cells

Cross Priming of Transgene Product-Specific CD8 + T Cells in Hepatic AAV Gene Transfer Depends on IL-1 Receptor and XCR1 + Dendritic Cells but Not TLR9

AAV Vector Dose Determines TLR9 Dependence of CD8+ T Cell Response to Transgene Product

Revisiting the "Danger Theory": Toll-like Receptor 9 Stimulation Triggers Activation of Conventional CD8α + and Plasmacytoid Dendritic Cells En Route to Enhancing FVIII Inhibitor Formation

Alternative Approaches to Oral Tolerance Induction to Factor FVIII

Toll-like Receptor 9 Activation Accelerates Inhibitor Formation in Response to Factor VIII

Update on clinical gene therapy for hemophilia

Reprogrammed CD4 + T Cells That Express FoxP3 + Effectively Control Inhibitory Antibody Development in Hemophilic Mice

Generation of FVIII-Specific Tregs Expressing a Chimeric Antigen Receptor (CAR) to Suppress Inhibitor Development in Hemophilia a Mice

Innate Immune Activation Via TLR9 May Enhance Antibody Formation Against Factors VIII and IX in Protein and Gene Therapy

Lettuce Plants Expressing High Levels of Factor VIII Antigen in the Chloroplast for Oral Tolerance in Hemophilia a

Plasmacytoid and conventional dendritic cells cooperate in crosspriming AAV capsid-specific CD8 + T cells

Driving the hemophilia tolerance CAR

Hepatic AAV Gene Transfer of Cytoplasmic Transgene Induces Transgene Product-Specific T Cell Activation Initially in the Liver and Celiac Lymph Node Preceding Treg Induction

AAV3 Capsid Is Superior for In Vivo Gene Transfer to Human Hepatocytes Compared to Serotypes 5 and 8 in a Mouse/Human Chimeric Model

Factor IX Expressed in Lettuce Chloroplasts Induces Oral Tolerance in Hemophilia B Mice

Synergy between rapamycin and FLT3 ligand enhances plasmacytoid dendritic cell–dependent induction of CD4 + CD25 + FoxP3 + Treg

Plant-based oral tolerance to hemophilia therapy employs a complex immune regulatory response including LAP + CD4 + T cells

Email alerts

ASH Publications

American Society of Hematology

Email alerts

ASH Publications

American Society of Hematology

This Feature Is Available To Subscribers Only