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Journal Articles

Bradykinin Receptors Regulate Proliferation, Migration and Tube Formation of Endothelial Progenitor Cells

Yi Wu, Nadia Backdash, Robert W. Colman

Blood (2014) 124 (21): 4176.

DOI: https://doi.org/10.1182/blood.V124.21.4176.4176

Published: 2014

Journal Articles

Cleaved High Molecular Weight Kininogen Induces Endothelial Progenitor Cell Senescence by Stimulation of JNK/FOXO4/MnSOD Pathway.

Xuemei Zhu, Robert W. Colman, Yi Wu

Blood (2012) 120 (21): 2181.

DOI: https://doi.org/10.1182/blood.V120.21.2181.2181

Published: 2012

Journal Articles

A Role for Activation of the Kallikrein-Kinin System in the Homing Property of Endothelial Progenitor Cells.

Yi Wu, PhD, Christina Hu, Robert W. Colman, MD

Blood (2008) 112 (11): 1884.

DOI: https://doi.org/10.1182/blood.V112.11.1884.1884

Published: 2008

Journal Articles

Cleaved High Molecular Weight Kininogen (HKa) and Kininostatin (D5) Induce Apoptosis and Inhibit Migration and Invasion of Human Prostate Cancer Cells by Preventing AKT Phosphorylation and Cyclin D1 Synthesis and Disrupting the Interaction of UPAR and EGFR.

Yuchuan Liu, PhD, Robin Pixley, Ph.D., Mario Fusaro, B.S., Robert W. Colman, M.D.

Blood (2007) 110 (11): 405.

DOI: https://doi.org/10.1182/blood.V110.11.405.405

Published: 2007

Journal Articles

Cleaved Kininogen Inhibits Endothelial Progenitor Cell Differentiation by Interfering with the avb3 Integrin-MMP-2 Pathway.

Robert W. Colman, MD, Noah G. Schmuckler, Yi Wu, Ph.D.

Blood (2007) 110 (11): 3719.

DOI: https://doi.org/10.1182/blood.V110.11.3719.3719

Published: 2007

Journal Articles

Thrombin regulates intracellular cyclic AMP concentration in human platelets through phosphorylation/activation of phosphodiesterase 3A

Wei Zhang, Robert W. Colman

Blood (2007) 110 (5): 1475–1482.

DOI: https://doi.org/10.1182/blood-2006-10-052522

Published: 2007

Journal Articles

High Molecular Weight Kininogen Fragments Stimulate the Secretion of Interleukin-1β through the NFκ B, JNK and p38 MAP Kinase Signaling Pathways in Monocytes.

Mohammad M. Khan, MD, PhD, Harland N. Bradford, Irma Isordia-Salas, Ph.D., Yuchuan Liu, Ph.D., Yi Wu, Ph.D., Ricardo G. Espinola, M.D., Berhane Ghebrehiwet, M.D., Robert W. Colman, M.D

Blood (2006) 108 (11): 1644.

DOI: https://doi.org/10.1182/blood.V108.11.1644.1644

Published: 2006

Journal Articles

Detachment of Human Endothelial Cells from Fibrinogen Induced by Cleaved High Molecular Weight Kininogen (HKa) Is Mediated by c-Jun Amino-Terminal Kinase (JNK) Signaling Pathway.

Yuchuan Liu, PhD, Irma M. Sainz, MD, Robin A. Pixley, PhD, Robert W. Colman, MD

Blood (2006) 108 (11): 1809.

DOI: https://doi.org/10.1182/blood.V108.11.1809.1809

Published: 2006

Journal Articles

Is the plasma kallikrein-kinin system antithrombotic?

Robert W. Colman

Blood (2006) 108 (1): 1–2.

DOI: https://doi.org/10.1182/blood-2006-04-016253

Published: 2006

Journal Articles

Truncated and Microparticle Free Soluble Tissue Factor Bound to Peripheral Monocytes Preferentially Activate Factor VII.

Mohammad Khan, MD, PhD, Takashi Hattori, PhD, Stefan Niewiarowski, MD, PhD, L. Henry Edmunds, Jr., MD, Robert W. Colman, MD

Blood (2005) 106 (11): 2232.

DOI: https://doi.org/10.1182/blood.V106.11.2232.2232

Published: 2005

Journal Articles

The Factor XI Receptor on Collagen Activated Platelets Is gC1qR/P33.

Frank A. Baglia, PhD, Harlan R. Bradford, Robert W. Colman, MD, Ellinor I.B. Peerschke, PhD, Berhane Ghebrehiwet, PhD, Peter N. Walsh, MD, PhD

Blood (2005) 106 (11): 690.

DOI: https://doi.org/10.1182/blood.V106.11.690.690

Published: 2005

Journal Articles

Interaction of High Molecular Weight Kininogen with Endothelial Cell Receptors suPAR, gC1qR and Cytokeratin 1 by Surface Plasmon Resonance (BiaCore).

Ricardo G. Espinola, Robin A. Pixley, Berhane Ghebrehiwet, Kusumam Joseph, Alice Kuo, Douglas B. Cines, Robert W. Colman

Blood (2005) 106 (11): 2666.

DOI: https://doi.org/10.1182/blood.V106.11.2666.2666

Published: 2005

Journal Articles

New Insights from the Structure Function of the Catalytic Region of Human Platelet PDE3A: The Role of the Unique 44 Amino Acid Insert.

Su-Hwi Hung, Wei Zhang, Jing Tao, Carolyn Kim, Rachel Noone, David Ezon, Roberta F. Colman, Robert W. Colman

Blood (2005) 106 (11): 3937.

DOI: https://doi.org/10.1182/blood.V106.11.3937.3937

Published: 2005

Journal Articles

High Molecular Weight Kininogen Fragments Stimulate the Secretion of Interleukin 1β through the Urokinase-Type Plasminogen Activator Receptor (uPAR) and CD11b/CD18 (Mac-1) in Human Blood Mononuclear Cells.

Mohammad M. Khan, M.D., Ph.D., Harlan N. Bradford, Irma Isordia-Salas, M.D., Ricardo Espinola, M.D., Robert W. Colman, M.D.

Blood (2004) 104 (11): 3800.

DOI: https://doi.org/10.1182/blood.V104.11.3800.3800

Published: 2004

Journal Articles

A Monoclonal Antibody to High Molecular Weight Kininogen Reduces Inflammation in the HLA-B27 Transgenic Rat Model of Inflammatory Bowel Disease and Arthritis.

Robin A. Pixley, Ph.D., Irma M. Sainz, M.D., James C. Keith, Jr., DVM, Ph.D., Irma Isordia-Salas, M.D., Yelena Leatherby, MS, Leo M. Albert, BVMSc, Robert W. Colman, M.D.

Blood (2004) 104 (11): 3437.

DOI: https://doi.org/10.1182/blood.V104.11.3437.3437

Published: 2004

Journal Articles

Thrombin Regulates the Camp Level in Human Platelets through Phosphorylation /Activation of Akt.

Wei Zhang, Ph.D., Gary Nale, B.S., Robert W. Colman, M.D.

Blood (2004) 104 (11): 3538.

DOI: https://doi.org/10.1182/blood.V104.11.3538.3538

Published: 2004

Journal Articles

The Antithrombotic Activity of Kininogen Is Mediated by Inhibitory Effects of Domain 3 on Thrombin-Induced Platelet Activation, In Vivo .

Sarmina Hassan, Ph.D., Mohammad M. Khan, M.D., Ph.D., Irma Isordia-Salas, M.D., Irma Sainz, M.D., Sakeen W. Kashem, Bo Liu, R. Balfour Sartor, M.D., Robert W. Colman, M.D.

Blood (2004) 104 (11): 799.

DOI: https://doi.org/10.1182/blood.V104.11.799.799

Published: 2004

Journal Articles

Activated Peripheral Mononuclear Cells Plus Soluble Plasma Tissue Factor Activate Factors VII and X in Cardiac Surgical Wounds.

Robert W. Colman, M.D., Mohammad M.H. Khan, M.D., Ph.D., Takashi Hattori, Ph.D., L. Henry Edmunds4, M.D.

Blood (2004) 104 (11): 806.

DOI: https://doi.org/10.1182/blood.V104.11.806.806

Published: 2004

Journal Articles

Inhibition of tumor angiogenesis in vivo by a monoclonal antibody targeted to domain 5 of high molecular weight kininogen

James S. Song, Irma M. Sainz, Stephen C. Cosenza, Irma Isordia-Salas, Abdel Bior, Harlan N. Bradford, Yan-Lin Guo, Robin A. Pixley, E. Premkumar Reddy, Robert W. Colman

Blood (2004) 104 (7): 2065–2072.

DOI: https://doi.org/10.1182/blood-2004-02-0449

Published: 2004

Journal Articles

The mutation Ser511Asn leads to N- glycosylation and increases the cleavage of high molecular weight kininogen in rats genetically susceptible to inflammation

Irma Isordia-Salas, Robin A. Pixley, Hemant Parekh, Satya P. Kunapuli, Fengling Li, Anthony Stadnicki, Yingzhang Lin, R. Balfour Sartor, Robert W. Colman

Blood (2003) 102 (8): 2835–2842.

DOI: https://doi.org/10.1182/blood-2003-02-0661

Published: 2003

NARROW

Bradykinin Receptors Regulate Proliferation, Migration and Tube Formation of Endothelial Progenitor Cells

Cleaved High Molecular Weight Kininogen Induces Endothelial Progenitor Cell Senescence by Stimulation of JNK/FOXO4/MnSOD Pathway.

A Role for Activation of the Kallikrein-Kinin System in the Homing Property of Endothelial Progenitor Cells.

Cleaved High Molecular Weight Kininogen (HKa) and Kininostatin (D5) Induce Apoptosis and Inhibit Migration and Invasion of Human Prostate Cancer Cells by Preventing AKT Phosphorylation and Cyclin D1 Synthesis and Disrupting the Interaction of UPAR and EGFR.

Cleaved Kininogen Inhibits Endothelial Progenitor Cell Differentiation by Interfering with the avb3 Integrin-MMP-2 Pathway.

Thrombin regulates intracellular cyclic AMP concentration in human platelets through phosphorylation/activation of phosphodiesterase 3A

High Molecular Weight Kininogen Fragments Stimulate the Secretion of Interleukin-1β through the NFκ B, JNK and p38 MAP Kinase Signaling Pathways in Monocytes.

Detachment of Human Endothelial Cells from Fibrinogen Induced by Cleaved High Molecular Weight Kininogen (HKa) Is Mediated by c-Jun Amino-Terminal Kinase (JNK) Signaling Pathway.

Is the plasma kallikrein-kinin system antithrombotic?

Truncated and Microparticle Free Soluble Tissue Factor Bound to Peripheral Monocytes Preferentially Activate Factor VII.

The Factor XI Receptor on Collagen Activated Platelets Is gC1qR/P33.

Interaction of High Molecular Weight Kininogen with Endothelial Cell Receptors suPAR, gC1qR and Cytokeratin 1 by Surface Plasmon Resonance (BiaCore).

New Insights from the Structure Function of the Catalytic Region of Human Platelet PDE3A: The Role of the Unique 44 Amino Acid Insert.

High Molecular Weight Kininogen Fragments Stimulate the Secretion of Interleukin 1β through the Urokinase-Type Plasminogen Activator Receptor (uPAR) and CD11b/CD18 (Mac-1) in Human Blood Mononuclear Cells.

A Monoclonal Antibody to High Molecular Weight Kininogen Reduces Inflammation in the HLA-B27 Transgenic Rat Model of Inflammatory Bowel Disease and Arthritis.

Thrombin Regulates the Camp Level in Human Platelets through Phosphorylation /Activation of Akt.

The Antithrombotic Activity of Kininogen Is Mediated by Inhibitory Effects of Domain 3 on Thrombin-Induced Platelet Activation, In Vivo .

Activated Peripheral Mononuclear Cells Plus Soluble Plasma Tissue Factor Activate Factors VII and X in Cardiac Surgical Wounds.

Inhibition of tumor angiogenesis in vivo by a monoclonal antibody targeted to domain 5 of high molecular weight kininogen

The mutation Ser511Asn leads to N- glycosylation and increases the cleavage of high molecular weight kininogen in rats genetically susceptible to inflammation

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American Society of Hematology

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American Society of Hematology

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