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Journal Articles

New Insights into Deregulated Gene Expression Pathways in MLL- and AF10 -Rearranged T-Lineage Acute Lymphoblastic Leukemia

Huining Kang, PhD, Nitesh Sharma, PhD, Christian K Nickl, Scott Ness, PhD, Meenakshi Devidas, PhD, Brent L. Wood, MD PhD, Barbara L. Asselin, MD, Elizabeth Raetz, MD, William L. Carroll, MD, Naomi Winick, MD, Mignon L. Loh, MD, Stephen P. Hunger, MD, Nyla A. Heerema, PhD, Andrew J. Carroll, PhD, Kimberly P. Dunsmore, MD, Richard S. Larson, MD PhD, Stuart S. Winter, MD, Ksenia Matlawska-Wasowska, PhD

Blood (2016) 128 (22): 2906.

https://doi.org/10.1182/blood.V128.22.2906.2906

Published: 2016

Journal Articles

Mixed Lineage Leukemia Rearrangements ( MLL- R ) Are Determinants of High Risk Disease in Homeobox A (HOXA)- deregulated T-Lineage Acute Lymphoblastic Leukemia: A Children's Oncology Group Study

Blood (2015) 126 (23): 694.

https://doi.org/10.1182/blood.V126.23.694.694

Published: 2015

Journal Articles

AF10 Fusion Transcripts Are Identified By HOXA9/10 and MEIS1 Overexpression In T-ALL: A Report From Children’s Oncology Group AALL0434

Ksenia Matlawska-Wasowska, PhD, Richard C. Harvey, PhD, Nyla A. Heerema, PhD, Andrew J. Carroll, PhD, Meenakshi Devidas, PhD, Mignon L. Loh, MD, Stephen P. Hunger, MD, Elizabeth A. Raetz, MD, Charles G. Mullighan, MBBS, MSc, MD, FRACP, FRCPA, Naomi J. Winick, MD, William L. Carroll, MD, Richard S. Larson, MD, PhD, Kimberly Dunsmore, MD, Peter D. Aplan, MD, Stuart S. Winter, MD

Blood (2013) 122 (21): 2601.

https://doi.org/10.1182/blood.V122.21.2601.2601

Published: 2013

Journal Articles

Expression Profiling for MEIS1 and HOXA9/10 Identifies an Increased Incidence of MLL Rearrangements in T-ALL: A Children's Oncology Group Study.

Ksenia Matlawska-Wasowska, PhD, Richard C. Harvey, PhD, I-Ming Chen, DVM, Cheryl L Willman, MD, Nyla A. Heerema, PhD, Andrew J. Carroll, PhD, Meenakshi Devidas, PhD, Mignon L. Loh, MD, Stephen P. Hunger, MD, Elizabeth Raetz, MD, Charles G Mullighan, MBBS, MD, FRACP, FRCPA, MSc, Barbara Asselin, MD, Naomi Winick, MD, William L. Carroll, MD, Richard S. Larson, MD, PhD, Kimberly P. Dunsmore, MD, Stuart S. Winter, MD

Blood (2012) 120 (21): 2505.

https://doi.org/10.1182/blood.V120.21.2505.2505

Published: 2012

Journal Articles

Inactivation of LEF1 in T-cell acute lymphoblastic leukemia

Alejandro Gutierrez, Takaomi Sanda, Wenxue Ma, Jianhua Zhang, Ruta Grebliunaite, Suzanne Dahlberg, Donna Neuberg, Alexei Protopopov, Stuart S. Winter, Richard S. Larson, Michael J. Borowitz, Lewis B. Silverman, Lynda Chin, Stephen P. Hunger, Catriona Jamieson, Stephen E. Sallan, A. Thomas Look

Blood (2010) 115 (14): 2845–2851.

https://doi.org/10.1182/blood-2009-07-234377

Published: 2010

Includes: Supplemental data

Journal Articles

Interconnecting molecular pathways in the pathogenesis and drug sensitivity of T-cell acute lymphoblastic leukemia

Takaomi Sanda, Xiaoyu Li, Alejandro Gutierrez, Yebin Ahn, Donna S. Neuberg, Jennifer O'Neil, Peter R. Strack, Christopher G. Winter, Stuart S. Winter, Richard S. Larson, Harald von Boehmer, A. Thomas Look

Blood (2010) 115 (9): 1735–1745.

https://doi.org/10.1182/blood-2009-07-235143

Published: 2010

Includes: Supplemental data

Journal Articles

Inactivation of the INK4A/ARF ( CDKN2 ) locus Cooperates with HMGA1 in T-Cell Leukemogenesis.

Linda Resar, MD, Francescopaolo Di Cello, Ph.D., Surajit Dhara, Ph.D., Jeanne Kowalski, Ph.D., Ossama Elbahlouh, M.D., Joelle Hillion, Ph.D., Stuart Winter, MD, Richard S. Larson, MD, PhD, David Huso, D.V.M., Ph.D.

Blood (2009) 114 (22): 3969.

https://doi.org/10.1182/blood.V114.22.3969.3969

Published: 2009

Journal Articles

Absence of T-Cell Receptor Gene Rearrangements Predicts Induction Failure in Pediatric T-Cell Acute Lymphoblastic Leukemia.

Alejandro Gutierrez, M.D., Ruta Grebliunaite, Suzanne E. Dahlberg, PhD, Donna Neuberg, ScD, Jianhua Zhang, PhD, Takaomi Sanda, M.D., Ph.D., Alexei Protopopov, Lynda Chin, MD, Stuart Winter, MD, Richard S. Larson, MD, PhD, Jeffery Lorne Kutok, MD, PhD, Lewis B. Silverman, MD, Stephen P Hunger, MD, Stephen E. Sallan, MD, A. Thomas Look, MD

Blood (2009) 114 (22): 910.

https://doi.org/10.1182/blood.V114.22.910.910

Published: 2009

Journal Articles

LEF1 Is a Tumor Suppressor in T Cell Acute Lymphoblastic Leukemia

Alejandro Gutierrez, MD, Takaomi Sanda, MD, PhD, Stuart Winter, MD, Richard S. Larson, MD, PhD, Lewis B. Silverman, MD, Stephen P. Hunger, MD, Stephen E. Sallan, MD, A. Thomas Look, MD

Blood (2008) 112 (11): 3802.

https://doi.org/10.1182/blood.V112.11.3802.3802

Published: 2008

Journal Articles

De Novo Expression of ATP Binding Cassette C1 (ABCC1) on T-ALL Cells Confers Resistance to Vincristine Independent of an MDR1 Phenotype.

Stuart S. Winter, MD, Hadya M. Khawaja, Debbie M. Lovato, Richard S. Larson, MD, PhD

Blood (2007) 110 (11): 2374.

https://doi.org/10.1182/blood.V110.11.2374.2374

Published: 2007

Journal Articles

Identification of genomic classifiers that distinguish induction failure in T-lineage acute lymphoblastic leukemia: a report from the Children's Oncology Group

Stuart S. Winter, Zeyu Jiang, Hadya M. Khawaja, Timothy Griffin, Meenakshi Devidas, Barbara L. Asselin, Richard S. Larson

Blood (2007) 110 (5): 1429–1438.

https://doi.org/10.1182/blood-2006-12-059790

Published: 2007

Includes: Supplemental data

Journal Articles

Identification of Off-Patent Drugs That Reverse Daunorubicin Efflux Mediated by ABCB1 in T-ALL Cells.

Stuart S. Winter, MD, Debbie M. Lovato, BS, Hadya M. Khawaja, MS, Bruce S. Edwards, PhD, Irena D. Steele, PhD, Susan M. Young, MS, Tudor I. Oprea, PhD, Larry A. Sklar, PhD, Richard S. Larson, MD, PhD

Blood (2006) 108 (11): 2603.

https://doi.org/10.1182/blood.V108.11.2603.2603

Published: 2006

Journal Articles

Identification of Genomic Classifiers That Distinguish Induction Failure in T-Lineage Acute Lymphoblastic Leukemia in COG Study 9404.

Stuart S. Winter, MD, Hadya Khawaja, Zeyu Jiang, PhD, Timothy Griffin, MD, Barbara Asselin, MD, Richard S. Larson, MD, PhD

Blood (2006) 108 (11): 1826.

https://doi.org/10.1182/blood.V108.11.1826.1826

Published: 2006

Journal Articles

Noninvasive Approach to Detection of T-Cell Mediated Graft Rejection through Antibody-Tagged Nanoparticles Using SQUID Detection.

Jason E. Jaetao, MS, Debbie M. Lovato, BS, Dmitri A. Sergatskov, PhD, Christian Bergemann, Howard C. Bryant, PhD, Edward R. Flynn, PhD, Richard S. Larson, MD,PhD

Blood (2006) 108 (11): 3220.

https://doi.org/10.1182/blood.V108.11.3220.3220

Published: 2006

Journal Articles

Identification of Chemotherapy-Resistant Mechanisms in Childhood T-ALL Cell Lines: Correlation with Genetic Profiles in Patients Having Early Treatment Failure.

David A. Estes, BS, Debbie M. Lovato, BS, Hadya M. Khawaja, MS, Stuart S. Winter, MD, Richard S. Larson, MD,PhD

Blood (2006) 108 (11): 4376.

https://doi.org/10.1182/blood.V108.11.4376.4376

Published: 2006

Journal Articles

Transcriptional regulatory networks downstream of TAL1/SCL in T-cell acute lymphoblastic leukemia

Teresa Palomero, Duncan T. Odom, Jennifer O'Neil, Adolfo A. Ferrando, Adam Margolin, Donna S. Neuberg, Stuart S. Winter, Richard S. Larson, Wei Li, X. Shirley Liu, Richard A. Young, A. Thomas Look

Blood (2006) 108 (3): 986–992.

https://doi.org/10.1182/blood-2005-08-3482

Published: 2006

Includes: Supplemental data

Journal Articles

Establishment and Indentification of Genetic Alterations in Chemotherapy-Resistant T-ALL Cell Lines.

David A. Estes, BS, Rahul Poria, MS, Debbie M. Lovato, BS, Hadya M. Khawaja, MS, Claudia L. Quan, Stuart S. Winter, MD, Richard S. Larson, MD/PhD

Blood (2005) 106 (11): 4423.

https://doi.org/10.1182/blood.V106.11.4423.4423

Published: 2005

Journal Articles

Microarray Analyses in a Case-Control Cohort of T-ALL Samples Identifies Gene Signature of Potential Prognostic Significance.

Stuart S. Winter, MD, Hadya Khawaja, Zeyu Jiang, PhD, Charles Kooperberg, PhD, Adolfo Ferrando, MD, Thomas Look, MD, Richard S. Larson, MD, PhD

Blood (2005) 106 (11): 1448.

https://doi.org/10.1182/blood.V106.11.1448.1448

Published: 2005

Journal Articles

Genome-Wide Transcriptional Regulatory Networks Downstream of TAL1/SCL in T-Cell Acute Lymphoblastic Leukemia.

Teresa Palomero, PhD, Duncan T. Odom, PhD, Jennifer O’Neil, PhD, Adolfo A. Ferrando, MD, PhD, Stuart S. Winter, MD, Richard S. Larson, MD, PhD, Richard A. Young, PhD, A. Thomas Look, MD

Blood (2004) 104 (11): 416.

https://doi.org/10.1182/blood.V104.11.416.416

Published: 2004

Journal Articles

Clinical description of 44 patients with acute promyelocytic leukemia who developed the retinoic acid syndrome: Presented in part at the meeting of the American Society of Hematology, San Diego, CA, December 1997.

Martin S. Tallman, Janet W. Andersen, Charles A. Schiffer, Frederick R. Appelbaum, James H. Feusner, Angela Ogden, Lois Shepherd, Jacob M. Rowe, Christopher François, Richard S. Larson, Peter H. Wiernik

Blood (2000) 95 (1): 90–95.

https://doi.org/10.1182/blood.V95.1.90

Published: 2000

NARROW

New Insights into Deregulated Gene Expression Pathways in MLL- and AF10 -Rearranged T-Lineage Acute Lymphoblastic Leukemia

Mixed Lineage Leukemia Rearrangements ( MLL- R ) Are Determinants of High Risk Disease in Homeobox A (HOXA)- deregulated T-Lineage Acute Lymphoblastic Leukemia: A Children's Oncology Group Study

AF10 Fusion Transcripts Are Identified By HOXA9/10 and MEIS1 Overexpression In T-ALL: A Report From Children’s Oncology Group AALL0434

Expression Profiling for MEIS1 and HOXA9/10 Identifies an Increased Incidence of MLL Rearrangements in T-ALL: A Children's Oncology Group Study.

Inactivation of LEF1 in T-cell acute lymphoblastic leukemia

Interconnecting molecular pathways in the pathogenesis and drug sensitivity of T-cell acute lymphoblastic leukemia

Inactivation of the INK4A/ARF ( CDKN2 ) locus Cooperates with HMGA1 in T-Cell Leukemogenesis.

Absence of T-Cell Receptor Gene Rearrangements Predicts Induction Failure in Pediatric T-Cell Acute Lymphoblastic Leukemia.

LEF1 Is a Tumor Suppressor in T Cell Acute Lymphoblastic Leukemia

De Novo Expression of ATP Binding Cassette C1 (ABCC1) on T-ALL Cells Confers Resistance to Vincristine Independent of an MDR1 Phenotype.

Identification of genomic classifiers that distinguish induction failure in T-lineage acute lymphoblastic leukemia: a report from the Children's Oncology Group

Identification of Off-Patent Drugs That Reverse Daunorubicin Efflux Mediated by ABCB1 in T-ALL Cells.

Identification of Genomic Classifiers That Distinguish Induction Failure in T-Lineage Acute Lymphoblastic Leukemia in COG Study 9404.

Noninvasive Approach to Detection of T-Cell Mediated Graft Rejection through Antibody-Tagged Nanoparticles Using SQUID Detection.

Identification of Chemotherapy-Resistant Mechanisms in Childhood T-ALL Cell Lines: Correlation with Genetic Profiles in Patients Having Early Treatment Failure.

Transcriptional regulatory networks downstream of TAL1/SCL in T-cell acute lymphoblastic leukemia

Establishment and Indentification of Genetic Alterations in Chemotherapy-Resistant T-ALL Cell Lines.

Microarray Analyses in a Case-Control Cohort of T-ALL Samples Identifies Gene Signature of Potential Prognostic Significance.

Genome-Wide Transcriptional Regulatory Networks Downstream of TAL1/SCL in T-Cell Acute Lymphoblastic Leukemia.

Clinical description of 44 patients with acute promyelocytic leukemia who developed the retinoic acid syndrome: Presented in part at the meeting of the American Society of Hematology, San Diego, CA, December 1997.

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American Society of Hematology

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