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Affimer proteins as a tool to modulate fibrinolysis, stabilize the blood clot, and reduce bleeding complications
Katherine J. Kearney, Nikoletta Pechlivani, Rhodri King, Christian Tiede, Fladia Phoenix, Ramsah Cheah, Fraser L. Macrae, Katie J. Simmons, Iain W. Manfield, Kerrie A. Smith, Benjamin E. J. Spurgeon, Khalid M. Naseem, Robert A. S. Ariens, Michael J. McPherson, Darren C. Tomlinson, Ramzi A. Ajjan
Blood (2019) 133 (11): 1233–1244.
Includes: Supplemental data
Thrombin and fibrinogen γ′ impact clot structure by marked effects on intrafibrillar structure and protofibril packing
Marco M. Domingues, Fraser L. Macrae, Cédric Duval, Helen R. McPherson, Katherine I. Bridge, Ramzi A. Ajjan, Victoria C. Ridger, Simon D. Connell, Helen Philippou, Robert A. S. Ariëns
Blood (2016) 127 (4): 487–495.
Includes: Multimedia, Supplemental data
Diabetes is associated with posttranslational modifications in plasminogen resulting in reduced plasmin generation and enzyme-specific activity
Ramzi A. Ajjan, Toby Gamlen, Kristina F. Standeven, Salihah Mughal, Katharina Hess, Kerrie A. Smith, Emma J. Dunn, M. Maqsud Anwar, Naila Rabbani, Paul J. Thornalley, Helen Philippou, Peter J. Grant
Blood (2013) 122 (1): 134–142.