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Rachel E. Piddock
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Journal Articles

Acute myeloid leukemia induces protumoral p16INK4a-driven senescence in the bone marrow microenvironment

Amina M. Abdul-Aziz, Yu Sun, Charlotte Hellmich, Christopher R. Marlein, Jayna Mistry, Eoghan Forde, Rachel E. Piddock, Manar S. Shafat, Adam Morfakis, Tarang Mehta, Federica Di Palma, Iain Macaulay, Christopher J. Ingham, Anna Haestier, Angela Collins, Judith Campisi, Kristian M. Bowles, Stuart A. Rushworth
Journal: Blood
Blood (2019) 133 (5): 446–456.
https://doi.org/10.1182/blood-2018-04-845420
Published: 2019
Includes: Supplemental data
Journal Articles

NOX2 Derived Superoxide Induces Pro-Tumoral p16INK4a Driven Senescence in the AML Bone Marrow Microenvironment

Charlotte Hellmich, MBBChir, BSc, MRCP, Amina Abdul-Aziz, MSc, Yu Sun, BSc, MSc, Christopher Richard Marlein, BSc, Eoghan Forde, Rachel E Piddock, BSc, Manar Shafat, MSc, Adam Morfakis, BSc, Mehta Tarang, Federica Di Palma, Christopher Ingham, Angela Collins, MBBS, Anna Haestier, Bsc, PgD MBBS, MRCOG, Judith Campisi, PhD, Kristian Bowles, MBBS, PhD, Stuart Rushworth, PhD BSc
Journal: Blood
Blood (2018) 132 (Supplement 1): 2770.
https://doi.org/10.1182/blood-2018-99-115274
Published: 2018
Journal Articles

All-Trans Retinoic Acid (ATRA) up-Regulates Cell Surface CD38 Expression Which Promotes Pro-Tumoral Mitochondrial Trafficking from Stromal Cells to Multiple Myeloma

Christopher Richard Marlein, BSc, Rebecca H Horton, Rachel E Piddock, BSc, Jayna J Mistry, BSc, Charlotte Hellmich, MBBChir, BSc, MRCP, Cesar A. Gomez, MD PhD FRCPath, Kristian Bowles, MBBS, PhD, Stuart Rushworth, PhD BSc
Journal: Blood
Blood (2018) 132 (Supplement 1): 3153.
https://doi.org/10.1182/blood-2018-99-110323
Published: 2018
Journal Articles

NADPH oxidase-2 derived superoxide drives mitochondrial transfer from bone marrow stromal cells to leukemic blasts

Christopher R. Marlein, Lyubov Zaitseva, Rachel E. Piddock, Stephen D. Robinson, Dylan R. Edwards, Manar S. Shafat, Zhigang Zhou, Matthew Lawes, Kristian M. Bowles, Stuart A. Rushworth
Journal: Blood
Blood (2017) 130 (14): 1649–1660.
https://doi.org/10.1182/blood-2017-03-772939
Published: 2017
Includes: Supplemental data
Journal Articles

Leukemic blasts program bone marrow adipocytes to generate a protumoral microenvironment

Manar S. Shafat, Thomas Oellerich, Sebastian Mohr, Stephen D. Robinson, Dylan R. Edwards, Christopher R. Marlein, Rachel E. Piddock, Matthew Fenech, Lyubov Zaitseva, Amina Abdul-Aziz, Jeremy Turner, Johnathan A. Watkins, Matthew Lawes, Kristian M. Bowles, Stuart A. Rushworth
Journal: Blood
Blood (2017) 129 (10): 1320–1332.
https://doi.org/10.1182/blood-2016-08-734798
Published: 2017
Includes: Supplemental data
Journal Articles

Bone Marrow Mesenchymal Stromal Cells Transfer Their Mitochondria to Acute Myeloid Leukaemia Blasts to Support Their Proliferation and Survival

Christopher Marlein, BSc, Lyubov Zaitseva, BSc, PhD, Rachel E Piddock, BSc, Stephen Robinson, BSc, PhD, Dylan R Edwards, BSc, PhD, Manar S Shafat, MSc, Kristian M Bowles, MBBS, PhD, Stuart A Rushworth, Ph DBSc
Journal: Blood
Blood (2016) 128 (22): 772.
https://doi.org/10.1182/blood.V128.22.772.772
Published: 2016
Journal Articles

Macrophage Migration Inhibitory Factor Drives Multiple Myeloma IL-6/8 Pro-Survival Signals in the Tumor Microenvironment

Rachel E Piddock, BSc, Amina M Abdul-Aziz, MSc., Martin J Auger, MB ChB, MD, Kristian M Bowles, MB BS, PhD, Stuart A Rushworth, PhDBSc
Journal: Blood
Blood (2015) 126 (23): 2988.
https://doi.org/10.1182/blood.V126.23.2988.2988
Published: 2015