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Journal Articles

Protease activity in single-chain prekallikrein

Ivan Ivanov, Ingrid M. Verhamme, Mao-fu Sun, Bassem Mohammed, Qiufang Cheng, Anton Matafonov, S. Kent Dickeson, Kusumam Joseph, Allen P. Kaplan, David Gailani

Blood (2020) 135 (8): 558–567.

https://doi.org/10.1182/blood.2019002224

Published: 2020

Includes: Supplemental data

Journal Articles

A mechanism for hereditary angioedema with normal C1 inhibitor: an inhibitory regulatory role for the factor XII heavy chain

Ivan Ivanov, Anton Matafonov, Mao-fu Sun, Bassem M. Mohammed, Qiufang Cheng, S. Kent Dickeson, Suman Kundu, Ingrid M. Verhamme, Andras Gruber, Keith McCrae, David Gailani

Blood (2019) 133 (10): 1152–1163.

https://doi.org/10.1182/blood-2018-06-860270

Published: 2019

Includes: Supplemental data

Journal Articles

Proteolytic properties of single-chain factor XII: a mechanism for triggering contact activation

Ivan Ivanov, Anton Matafonov, Mao-fu Sun, Qiufang Cheng, S. Kent Dickeson, Ingrid M. Verhamme, Jonas Emsley, David Gailani

Blood (2017) 129 (11): 1527–1537.

https://doi.org/10.1182/blood-2016-10-744110

Published: 2017

Includes: Supplemental data

Journal Articles

Discovery and Characterization of a Highly Specific Antibody Inhibitor of Factor XIIa, and the Subsequent Generation of a Factor XIIa/Plasma Kallikrein Bispecific Antibody

Blood (2015) 126 (23): 2268.

https://doi.org/10.1182/blood.V126.23.2268.2268

Published: 2015

Journal Articles

Activated factor XI increases the procoagulant activity of the extrinsic pathway by inactivating tissue factor pathway inhibitor

Cristina Puy, Erik I. Tucker, Anton Matafonov, Qiufang Cheng, Keith D. Zientek, Dave Gailani, András Gruber, Owen J. T. McCarty

Blood (2015) 125 (9): 1488–1496.

https://doi.org/10.1182/blood-2014-10-604587

Published: 2015

Includes: Supplemental data

Journal Articles

Factor XII inhibition reduces thrombus formation in a primate thrombosis model

Anton Matafonov, Philberta Y. Leung, Adam E. Gailani, Stephanie L. Grach, Cristina Puy, Qiufang Cheng, Mao-fu Sun, Owen J. T. McCarty, Erik I. Tucker, Hiroaki Kataoka, Thomas Renné, James H. Morrissey, Andras Gruber, David Gailani

Blood (2014) 123 (11): 1739–1746.

https://doi.org/10.1182/blood-2013-04-499111

Published: 2014

Includes: Supplemental data

Journal Articles

The dimeric structure of factor XI and zymogen activation

Yipeng Geng, Ingrid M. Verhamme, Stephen B. Smith, Mao-fu Sun, Anton Matafonov, Qiufang Cheng, Stephanie A. Smith, James H. Morrissey, David Gailani

Blood (2013) 121 (19): 3962–3969.

https://doi.org/10.1182/blood-2012-12-473629

Published: 2013

Journal Articles

Antibodies to Human Factor XII with Antithrombotic Properties

Anton Matafonov, MD, Adam E. Gailani, Stephanie L. Grach, Philberta Y Leung, PhD, Qiufang Cheng, MD, Yipeng Geng, Owen J.T. McCarty, PhD, Erik I Tucker, PhD, Thomas Renne, MD, PhD, James H. Morrissey, PhD, Andras Gruber, MD, David Gailani, MD

Blood (2012) 120 (21): 1106.

https://doi.org/10.1182/blood.V120.21.1106.1106

Published: 2012

Journal Articles

The Interaction of Coagulation Factor XI with Polyphosphate

Yipeng Geng, Ingrid M. Verhamme, PhD, Qiufang Cheng, MD, Anton Matafonov, MD, Stephen B. Smith, PhD, Mao-fu Sun, Stephanie A. Smith, DVM, MS, James H. Morrissey, PhD, David Gailani, MD

Blood (2012) 120 (21): 498.

https://doi.org/10.1182/blood.V120.21.498.498

Published: 2012

Journal Articles

Evidence for a Factor IX-Independent Role for Factor XI in Thrombin Generation

Anton Matafonov, MD, Qiufang Cheng, MD, Ingrid M. Verhamme, PhD, Obi Umunakwe, Erik I. Tucker, PhD, Mao-fu Sun, Andras Gruber, MD, David Gailani, MD

Blood (2011) 118 (21): 2244.

https://doi.org/10.1182/blood.V118.21.2244.2244

Published: 2011

Journal Articles

A role for factor XIIa–mediated factor XI activation in thrombus formation in vivo

Qiufang Cheng, Erik I. Tucker, Meghann S. Pine, India Sisler, Anton Matafonov, Mao-fu Sun, Tara C. White-Adams, Stephanie A. Smith, Stephen R. Hanson, Owen J. T. McCarty, Thomas Renné, András Gruber, David Gailani

Blood (2010) 116 (19): 3981–3989.

https://doi.org/10.1182/blood-2010-02-270918

Published: 2010

Includes: Supplemental data

Journal Articles

Evidence against a protein in plasma that is a product of a factor XI mRNA splice variant missing exons 6 and 7

David Gailani, Mao-fu Sun, Qiufang Cheng, Anton Matafonov, Erik I. Tucker, Andras Gruber, Jonas Emsley

Blood (2010) 116 (7): 1185–1186.

https://doi.org/10.1182/blood-2010-01-265702

Published: 2010

Journal Articles

Factor XI Deficiency Confers a Survival Advantage in a Murine Sepsis Model.

David Gailani, MD, Erik I. Tucker, BS, Qiufang Cheng, MD, Stephen R. Hanson, PhD, Andras Gruber, MD

Blood (2006) 108 (11): 1005.

https://doi.org/10.1182/blood.V108.11.1005.1005

Published: 2006

Journal Articles

The effects of intrinsic pathway protease deficiencies on plasminogen-deficient mice

Qiufang Cheng, Yong Zhao, William E. Lawson, Vasiliy V. Polosukhin, Joyce E. Johnson, Timothy S. Blackwell, David Gailani

Blood (2005) 106 (9): 3055–3057.

https://doi.org/10.1182/blood-2005-02-0577

Published: 2005

Journal Articles

Effect of Factor XI or Factor IX Deficiency on an Arterial Occlusion Model.

David Gailani, MD, Qiufang Cheng, MD, Lin Xu, MD, Martin Ogletree, Ph.D., Xinkang Wang, Ph.D.

Blood (2004) 104 (11): 3501.

https://doi.org/10.1182/blood.V104.11.3501.3501

Published: 2004

Journal Articles

Model for a factor IX activation complex on blood platelets: dimeric conformation of factor XIa is essential

David Gailani, David Ho, Mao-Fu Sun, Qiufang Cheng, Peter N. Walsh

Blood (2001) 97 (10): 3117–3122.

https://doi.org/10.1182/blood.V97.10.3117

Published: 2001

NARROW

Protease activity in single-chain prekallikrein

A mechanism for hereditary angioedema with normal C1 inhibitor: an inhibitory regulatory role for the factor XII heavy chain

Proteolytic properties of single-chain factor XII: a mechanism for triggering contact activation

Discovery and Characterization of a Highly Specific Antibody Inhibitor of Factor XIIa, and the Subsequent Generation of a Factor XIIa/Plasma Kallikrein Bispecific Antibody

Activated factor XI increases the procoagulant activity of the extrinsic pathway by inactivating tissue factor pathway inhibitor

Factor XII inhibition reduces thrombus formation in a primate thrombosis model

The dimeric structure of factor XI and zymogen activation

Antibodies to Human Factor XII with Antithrombotic Properties

The Interaction of Coagulation Factor XI with Polyphosphate

Evidence for a Factor IX-Independent Role for Factor XI in Thrombin Generation

A role for factor XIIa–mediated factor XI activation in thrombus formation in vivo

Evidence against a protein in plasma that is a product of a factor XI mRNA splice variant missing exons 6 and 7

Factor XI Deficiency Confers a Survival Advantage in a Murine Sepsis Model.

The effects of intrinsic pathway protease deficiencies on plasminogen-deficient mice

Effect of Factor XI or Factor IX Deficiency on an Arterial Occlusion Model.

Model for a factor IX activation complex on blood platelets: dimeric conformation of factor XIa is essential

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American Society of Hematology

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