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Journal Articles

CTX-8573, an Innate-Cell Engager Targeting BCMA, is a Highly Potent Multispecific Antibody for the Treatment of Multiple Myeloma

Blood (2019) 134 (Supplement_1): 3182.

https://doi.org/10.1182/blood-2019-128749

Published: 2019

Journal Articles

Bone Marrow Microenvironment Induces Genomic Instability and Enables Clonal Evolution in Multiple Myeloma

Tommaso Perini, MD, Raphael Szalat, MD, Mariateresa Fulciniti, PhD, Mehmet Kemal Samur, PhD, Michael A Lopez, BS, Puru Nanjappa, Kenneth Wen, BS, Na Li, MD, Yan Xu, MD, Yu-Tzu Tai, PhD, Masood A. Shammas, PhD, Kenneth C Anderson, MD, Fabio Ciceri, MD, Nikhil Munshi, MD

Blood (2017) 130 (Supplement 1): 4408.

https://doi.org/10.1182/blood.V130.Suppl_1.4408.4408

Published: 2017

Journal Articles

Perturbation in B Cell-Subsets Can Explain the Observed Suppression of Uninvolved Immunoglobulins and Their Impact on T Tell-Subsets As Well As Patients Outcome in Myeloma

Rao Prabhala, PhD, Shree Acharya, MS, Megan Stekla, BS, Srikanth Talluri, PhD, Raphael Szalat, MD, Puru Nanjappa, Michael A Lopez, BS, Kenneth Wen, BS, Chaitanya Yenumula, MD, Alexander Heubeck, BS, Yu-Tzu Tai, PhD, Ansh Mehta, MBBS, Mariateresa Fulciniti, PhD, Suzan Lazo-Kallanian, BS, John Daley, PhD, Paul G Richardson, MD, Kenneth C Anderson, MD, Nikhil Munshi, MD

Blood (2017) 130 (Supplement 1): 3049.

https://doi.org/10.1182/blood.V130.Suppl_1.3049.3049

Published: 2017

Journal Articles

Identifying Novel Genes Involved in Dysregulation of Homologous Recombination and Genomic Integrity in Myeloma

Subodh Kumar, PhD, Leutz Buon, Mehmet Kemal Samur, PhD, Puru Nanjappa, Srikanth Talluri, PhD, Masood A. Shammas, PhD, Nikhil Munshi, MD

Blood (2017) 130 (Supplement 1): 3050.

https://doi.org/10.1182/blood.V130.Suppl_1.3050.3050

Published: 2017

Journal Articles

Immune Microenvironment Contributes to Dysregulation of Aid/Apobec Expression and Genomic Instability in Multiple Myeloma

Srikanth Talluri, PhD, Mehmet Kemal Samur, PhD, Puru Nanjappa, Chaitanya Yenumula, MD, Rao Prabhala, PhD, Masood A. Shammas, PhD, Nikhil Munshi, MD

Blood (2017) 130 (Supplement 1): 4333.

https://doi.org/10.1182/blood.V130.Suppl_1.4333.4333

Published: 2017

Journal Articles

Apobec Family of Proteins Mediate Genomic Changes in Multiple Myeloma By Inducing DNA Damage and C>T Mutations

Srikanth Talluri, PhD, Mehmet Kemal Samur, PhD, Leutz Buon, Puru Nanjappa, Rao Prabhala, PhD, Masood A. Shammas, PhD, Nikhil Munshi, MD

Blood (2017) 130 (Supplement 1): 4334.

https://doi.org/10.1182/blood.V130.Suppl_1.4334.4334

Published: 2017

Journal Articles

Targeting Homologous Recombination Increases Cytotoxicity While Reducing Genomic Instability Induced By Melphalan in Myeloma

Subodh Kumar, PhD, Srikanth Talluri, PhD, Puru Nanjappa, Masood A. Shammas, PhD, Nikhil Munshi, MD

Blood (2017) 130 (Supplement 1): 4388.

https://doi.org/10.1182/blood.V130.Suppl_1.4388.4388

Published: 2017

Journal Articles

Dysregulation of SHFM1, a Novel Target for Prevention of Genomic Instability in Myeloma, Is Associated with Epigenetic Changes at Specific CpG Sites

Masood Shammas, PhD, Subodh Kumar, PhD, Jagannath Pal, PhD, Puru Nanjappa, MS, Mehmat Samur, PhD, Maria Gkotzamanidou, MD PhD, Jialan Shi, MD PhD, Nikhil C. Munshi, MD

Blood (2014) 124 (21): 862.

https://doi.org/10.1182/blood.V124.21.862.862

Published: 2014

Journal Articles

Telomerase-Mediated Repair of Induced DNA Breaks Leads to Increased Genomic Instability in Multiple Myeloma Cells: Possible Mechanism and Translational Significance

Jagannath Pal, PhD, Masood Shammas, PhD, Subodh Kumar, PhD, Maria Gkotzamanidou, MD PhD, Puru Nanjappa, MS, Leutz Buon, Nikhil C. Munshi, MD

Blood (2014) 124 (21): 5170.

https://doi.org/10.1182/blood.V124.21.5170.5170

Published: 2014

Journal Articles

Ongoing Spontaneous DNA Damage and the Role of Aberrant Epigenome in Multiple Myeloma

Maria Gkotzamanidou, MD PhD, Masood Shammas, PhD, Vassilis L. Souliotis, Weihua Song, MD, Jagannath Pal, MBBS, PhD, Puru Nanjappa, MS, Naim Rashid, PhD, Kenneth C. Anderson, MD, Meletios A. Dimopoulos, MD, James Bradner, MD, Nikhil C. Munshi, MD

Blood (2014) 124 (21): 3398.

https://doi.org/10.1182/blood.V124.21.3398.3398

Published: 2014

Journal Articles

IL-17A-Mediated Notch Signaling in Multiple Myeloma

Rao H. Prabhala, PhD, Teru Hideshima, MD PhD, Mariateresa Fulciniti, PhD, Sophia Adamia, PhD, Rajya Lakshmi Bandi, BS, Puru Nanjappa, MS, Kenneth C. Anderson, Nikhil C. Munshi, MD

Blood (2014) 124 (21): 3434.

https://doi.org/10.1182/blood.V124.21.3434.3434

Published: 2014

Journal Articles

Elevated APE1 Mediates Dysregulation of Homologous Recombination in Myeloma: Mechanisms and Translational Significance

Subodh Kumar, PhD, Maria Gkotzamanidou, MD PhD, Jagannath Pal, PhD, Renquan Lu, MD PhD, Puru Nanjappa, MS, Jialan Shi, MD PhD, Masood Shammas, PhD, Nikhil C. Munshi, MD

Blood (2014) 124 (21): 2074.

https://doi.org/10.1182/blood.V124.21.2074.2074

Published: 2014

Journal Articles

Elevated Nuclease Activity Correlates With Clinical Spectrum Of Plasma Cell Dyscrasias

Jaymin M. Patel, MD, Ankit V Vahia, PhD, Puru Nanjappa, MS, Ashun Bajwa, BA, Sima Shah, Tai Yu-Tzu, Ph.D., Kenneth C. Anderson, MD, Masood Shammas, PhD, Nikhil C. Munshi, MD

Blood (2013) 122 (21): 4885.

https://doi.org/10.1182/blood.V122.21.4885.4885

Published: 2013

Journal Articles

Role Of Base Excision Repair Associated AP Nuclease Activity In The Induction Of Homologous Recombination Repair Pathway and Survival Of MM Cells Following DNA Damage

Subodh Kumar, PhD, Jagannath Pal, PhD, Jialan Shi, PhD, Puru Nanjappa, MS, Maria Gkotzamanidou, MD, Masood Shammas, PhD, Nikhil Munshi, MD

Blood (2013) 122 (21): 1248.

https://doi.org/10.1182/blood.V122.21.1248.1248

Published: 2013

Journal Articles

Multiple Myeloma Cells Express IL-17A Creating An Autocrine Loop: An Attractive Therapeutic Target

Rao H. Prabhala, Ph.D., Mariateresa Fulcinitti, PhD, Dheeraj Pelluru, PhD, Harsha K. Prabhala, MS, Naim Rashid, PhD, Adam Sperling, MD, PhD, Puru Nanjappa, MS, Saem Lee, B.A., Andreea Negroiu, MD, Suzan Lazo-Kallanian, BS, Aditya Munshi, MD, Paul G. Richardson, MD, John Daley, PhD, Kenneth C. Anderson, MD, Nikhil C. Munshi, MD

Blood (2013) 122 (21): 3113.

https://doi.org/10.1182/blood.V122.21.3113.3113

Published: 2013

Journal Articles

Reprogramming Aberrant B Cell-Subsets to Improve Immune Function in Multiple Myeloma

Rao H. Prabhala, Ph.D., Andreea Negroiu, MD, Saem Lee, B.A., Mariateresa Fulciniti, PhD, Puru Nanjappa, Ms, Harsha K. Prabhala, Adithya Munshi, MD, Irene M. Ghobrial, MD, Paul G. Richardson, MD, Jacob Laubach, MD, John Daley, PhD, Steven P. Treon, M.D., Ph.D., Charles Allam, MD, Kenneth C. Anderson, MD, Nikhil C Munshi, MD

Blood (2012) 120 (21): 3986.

https://doi.org/10.1182/blood.V120.21.3986.3986

Published: 2012

Journal Articles

Direct Evidence and Functional Significance of DNA Repair by Telomerase in Multiple Myeloma

Jagannath Pal, Renquan Lu, Puru Nanjappa, Ms, Ankit V Vahia, PhD, Masood A Shammas, PhD, Nikhil C Munshi, MD

Blood (2012) 120 (21): 4416.

https://doi.org/10.1182/blood.V120.21.4416.4416

Published: 2012

Journal Articles

A Novel Role of Telomerase in DNA Repair and Genome Maintenance in Myeloma.

Jagannath Pal, PhD, Puru Nanjappa, Ms, Ankit V Vahia, PhD, Jialan Shi, MD, PhD, Masood A Shammas, PhD, Nikhil C. Munshi, MD

Blood (2011) 118 (21): 628.

https://doi.org/10.1182/blood.V118.21.628.628

Published: 2011

Journal Articles

Elevated APEX1 Endonuclease Is Associated with Increased DNA Breaks and Instability in Myeloma

Masood Shammas, Ph.D, Jagannath Pal, PhD, Ankit V Vahia, Ph.D, Puru Nanjappa, Ms, Manit N Munshi, Jialan Shi, MD, PhD, Nikhil C. Munshi, MD

Blood (2011) 118 (21): 1805.

https://doi.org/10.1182/blood.V118.21.1805.1805

Published: 2011

Journal Articles

Elevated Homologous Recombination Induces Karyotypic Changes and Predicts Poor Clinical Outcome In Multiple Myeloma

Jagannath Pal, Jeffrey Sawyer, Samir B. Amin, MBBS, Cheng Li, Puru Nanjappa, Saem Lee, B.A., Stephane Minvielle, Hervé Avet-Loiseau, Masood Shammas, Nikhil C. Munshi

Blood (2010) 116 (21): 1924.

https://doi.org/10.1182/blood.V116.21.1924.1924

Published: 2010

NARROW

CTX-8573, an Innate-Cell Engager Targeting BCMA, is a Highly Potent Multispecific Antibody for the Treatment of Multiple Myeloma

Bone Marrow Microenvironment Induces Genomic Instability and Enables Clonal Evolution in Multiple Myeloma

Perturbation in B Cell-Subsets Can Explain the Observed Suppression of Uninvolved Immunoglobulins and Their Impact on T Tell-Subsets As Well As Patients Outcome in Myeloma

Identifying Novel Genes Involved in Dysregulation of Homologous Recombination and Genomic Integrity in Myeloma

Immune Microenvironment Contributes to Dysregulation of Aid/Apobec Expression and Genomic Instability in Multiple Myeloma

Apobec Family of Proteins Mediate Genomic Changes in Multiple Myeloma By Inducing DNA Damage and C>T Mutations

Targeting Homologous Recombination Increases Cytotoxicity While Reducing Genomic Instability Induced By Melphalan in Myeloma

Dysregulation of SHFM1, a Novel Target for Prevention of Genomic Instability in Myeloma, Is Associated with Epigenetic Changes at Specific CpG Sites

Telomerase-Mediated Repair of Induced DNA Breaks Leads to Increased Genomic Instability in Multiple Myeloma Cells: Possible Mechanism and Translational Significance

Ongoing Spontaneous DNA Damage and the Role of Aberrant Epigenome in Multiple Myeloma

IL-17A-Mediated Notch Signaling in Multiple Myeloma

Elevated APE1 Mediates Dysregulation of Homologous Recombination in Myeloma: Mechanisms and Translational Significance

Elevated Nuclease Activity Correlates With Clinical Spectrum Of Plasma Cell Dyscrasias

Role Of Base Excision Repair Associated AP Nuclease Activity In The Induction Of Homologous Recombination Repair Pathway and Survival Of MM Cells Following DNA Damage

Multiple Myeloma Cells Express IL-17A Creating An Autocrine Loop: An Attractive Therapeutic Target

Reprogramming Aberrant B Cell-Subsets to Improve Immune Function in Multiple Myeloma

Direct Evidence and Functional Significance of DNA Repair by Telomerase in Multiple Myeloma

A Novel Role of Telomerase in DNA Repair and Genome Maintenance in Myeloma.

Elevated APEX1 Endonuclease Is Associated with Increased DNA Breaks and Instability in Myeloma

Elevated Homologous Recombination Induces Karyotypic Changes and Predicts Poor Clinical Outcome In Multiple Myeloma

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American Society of Hematology

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ASH Publications

American Society of Hematology

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