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Journal Articles

The Pattern of Organ Responses Varies in Patients with Systemic Light-Chain Amyloidosis and Heart or Kidney or Heart and Kidney Involvement Who Achieve Deep Hematologic Responses

Diana Zhang, Danai Dima, Mumtu Lalla, Denis Toskic, Ping Zhou, Amandeep Godara, Raymond Comenzo

Blood (2021) 138 (Supplement 1): 2715.

DOI: https://doi.org/10.1182/blood-2021-148767

Published: 2021

Journal Articles

Results from a Phase 2 Study of a Novel Janus Kinase Inhibitor in Treatment of Patients with Myelofibrosis

Blood (2021) 138 (Supplement 1): 387.

DOI: https://doi.org/10.1182/blood-2021-145664

Published: 2021

Journal Articles

Therapeutic Activity of Combining BCL-2 and HMG-CoA Reductase Inhibition in Systemic Light-Chain Amyloidosis

Ping Zhou, MDPhD, Hashim Mann, MD, Xun Ma, DMD, MSc, PhD, Teresa Fogaren, NP, Yifei Zhang, MD, Denis Toskic, BS, Chakra P Chaulagain, MD, Cindy Varga, MDBSc, Raymond L. Comenzo, MD, Amandeep Godara, MD

Blood (2020) 136 (Supplement 1): 23–24.

DOI: https://doi.org/10.1182/blood-2020-142656

Published: 2020

Journal Articles

Risk and Prognostic Factors for Intracranial Hemorrhage in Elderly Patients with Immune Thrombocytopenia

Jia-Ning Zhang, Peng Zhao, Kaiyan Liu, Ming Hou, Yanqiu Han, PhD, Jian-Da Hu, PhD, Ze-Ping Zhou, Xin Wang, MDPhD, Ru Feng, Lin-Hua Yang, MD, He-Bing Zhou, Tie-nan Zhu, MD, Ye Jun Wu, Xiao-Hui Zhang

Blood (2020) 136 (Supplement 1): 14–15.

DOI: https://doi.org/10.1182/blood-2020-136461

Published: 2020

Journal Articles

In Systemic Light-Chain Amyloidosis Complete and Very Good Partial Responses Are Not Enough: Involved Free Light Chain (iFLC) Levels < 10mg/L Are Associated with Optimal Long-Term Survival

Amandeep Godara, MD, Denis Toskic, BS, Benjamin Rosenthal, BS, Cindy Varga, MD BSc, Adin Kugelmass, BSc, Ping Zhou, MD PhD, Teresa Fogaren, NP, Raymond L Comenzo, MD

Blood (2019) 134 (Supplement_1): 4369.

DOI: https://doi.org/10.1182/blood-2019-127004

Published: 2019

Journal Articles

B-Cell Maturation Antigen (BCMA) in Systemic Light-Chain Amyloidosis (AL): Association with Disease Activity and Its Modulation with Gamma-Secretase Inhibition

Amandeep Godara, MD, Ping Zhou, MD PhD, Benjamin Rosenthal, BS, Adin Kugelmass, BSc, Denis Toskic, BS, Teresa Fogaren, NP, Cindy Varga, MD BSc, Raymond L Comenzo, MD

Blood (2019) 134 (Supplement_1): 4409.

DOI: https://doi.org/10.1182/blood-2019-126988

Published: 2019

Journal Articles

Seeking AL Amyloidosis Very Early: The SAVE Trial — Identifying Clonal Lambda Light Chain Genes in Patients with MGUS or Smoldering Multiple Myeloma

Ping Zhou, MD PhD, Adin Kugelmass, BSc, Denis Toskic, Melissa Warner, BS, Lisa X. Lee, MD, Teresa Fogaren, NP, Cindy Varga, MD BSc, Raymond L Comenzo, MD

Blood (2018) 132 (Supplement 1): 1903.

DOI: https://doi.org/10.1182/blood-2018-99-112902

Published: 2018

Journal Articles

Potential Long-Term Treatment of Hemophilia a By Early Postnatal Co-Transplantation of Cord Blood Derived Endothelial Colony-Forming Cells and Placental Mesenchymal Stem Cells

Kewa Gao, MD, Priyadarsini Kumar, PhD, Dake Hao, PhD, Lizette Reynaga, BS, Diana Lee Farmer, MD, Melanie Rose, MS, Jan A. Nolta, PhD, Jianda Zhou, MD PhD, Ping Zhou, PhD, Aijun Wang, PhD

Blood (2018) 132 (Supplement 1): 3318.

DOI: https://doi.org/10.1182/blood-2018-99-117701

Published: 2018

Journal Articles

Senescent CD8+ T Cells in Myeloma Patients: Implications for Cellular Therapies

Lisa Xingguang Lee, MD, Denis Toskic, Xun Ma, DMD, MSc, PhD, Ping Zhou, MD PhD, Adin Kugelmass, BSc, Teresa Fogaren, NP, Raymond L Comenzo, MD

Blood (2018) 132 (Supplement 1): 5688.

DOI: https://doi.org/10.1182/blood-2018-99-118514

Published: 2018

Journal Articles

Effective Lipidoid Nanoparticle Delivery In Vivo of siRNA Targeting Kappa Light Chain Production in a Murine Xenograft Model

Xun Ma, DMD, MSc, PhD, Ping Zhou, MD PhD, Adin Kugelmass, BSc, Denis Toskic, Melissa Warner, BS, Lisa X. Lee, MD, Teresa Fogaren, NP, Ming Wang, PhD, Yamin Li, Liu Yang, Qiaobing Xu, Raymond Comenzo

Blood (2018) 132 (Supplement 1): 3208.

DOI: https://doi.org/10.1182/blood-2018-99-112682

Published: 2018

Journal Articles

Identifying a Murine Xenograft Model Relevant to Light-Chain Specific Approaches to Human Ig Light-Chain Diseases

Adin Kugelmass, BSc, Ping Zhou, MD PhD, Xun Ma, DMD, MSc, PhD, Denis Toskic, Amandeep Godara, MD, Melissa Warner, BS, Lisa Xingguang Lee, MD, Teresa Fogaren, NP, Cindy Varga, MD BSc, Raymond L Comenzo, MD

Blood (2018) 132 (Supplement 1): 5611.

DOI: https://doi.org/10.1182/blood-2018-99-119381

Published: 2018

Journal Articles

Daratumumab Activity Is Agnostic to Fc Gamma Receptor 3A (FcγR3A) 158 Genotype in Patients with Primary Refractory or Relapsed Systemic AL Amyloidosis

Lisa Xingguang Lee, MD, Katelynn Ho, Ping Zhou, PhD MD, Cindy Varga, MD BSc, Teresa Fogaren, NP, Denis Toskic, Adin Kugelmass, Raymond Comenzo, MD

Blood (2017) 130 (Supplement 1): 3164.

DOI: https://doi.org/10.1182/blood.V130.Suppl_1.3164.3164

Published: 2017

Journal Articles

Alu-Element Insertion in Pklr Gene As a Novel Cause of Severe Hereditary Nonspherocytic Hemolytic Anemia

Harry Lesmana, MD, Lisa Dyer, PhD, Ping Zhou, Xia Li, PhD, James Denton, MS, Satheesh Chonat, MD, Kejian Zhang, MD MBA, Robert J. Hopkin, MD, Theodosia A. Kalfa, MD PhD

Blood (2015) 126 (23): 3349.

DOI: https://doi.org/10.1182/blood.V126.23.3349.3349

Published: 2015

Journal Articles

Cytokinesis failure in RhoA-deficient mouse erythroblasts involves actomyosin and midbody dysregulation and triggers p53 activation

Diamantis G. Konstantinidis, Katie M. Giger, Mary Risinger, Suvarnamala Pushkaran, Ping Zhou, Phillip Dexheimer, Satwica Yerneni, Paul Andreassen, Ursula Klingmüller, James Palis, Yi Zheng, Theodosia A. Kalfa

Blood (2015) 126 (12): 1473–1482.

DOI: https://doi.org/10.1182/blood-2014-12-616169

Published: 2015

Includes: Supplemental data

Journal Articles

siRNA for the Ig Light Chain Constant Region Reduces Light Chain Production and Secretion By Human Plasma Cells and in a Murine Xenograft Model

Xun Ma, DDS, PhD, Ping Zhou, MD PhD, Monika Pilichowska, MD, Chakra P Chaulagain, MD FACP, Sandy Wong, MD, Raymond L. Comenzo, MD

Blood (2014) 124 (21): 5722.

DOI: https://doi.org/10.1182/blood.V124.21.5722.5722

Published: 2014

Journal Articles

One siRNA pool targeting the λ constant region stops λ light-chain production and causes terminal endoplasmic reticulum stress

Ping Zhou, Xun Ma, Lakshmanan Iyer, Chakra Chaulagain, Raymond L. Comenzo

Blood (2014) 123 (22): 3440–3451.

DOI: https://doi.org/10.1182/blood-2013-10-535187

Published: 2014

Includes: Supplemental data

Journal Articles

RhoA Gtpase Regulates Erythroblast Cytokinesis and Enucleation By Dynamic Coordination Of The Microtubule-Actomyosin Machineries For Successful Abscission

Diamantis G. Konstantinidis, PhD, Suvarnamala Pushkaran, M.Sc., Katie M. Giger, PhD, Ping Zhou, B.S., Paul R. Andreassen, PhD, Ursula Klingmuller, PhD, James Palis, M.D., Yi Zheng, PhD, Theodosia A. Kalfa, M.D., Ph.D.

Blood (2013) 122 (21): 311.

DOI: https://doi.org/10.1182/blood.V122.21.311.311

Published: 2013

Journal Articles

Acute Lymphoblastic Leukemia Is a Bcl-2 Dependent Disease: Proteomic Profiling and Pre-Clinical Efficacy Of a Selective Bcl-2 Antagonist ABT-199

Blood (2013) 122 (21): 3919.

DOI: https://doi.org/10.1182/blood.V122.21.3919.3919

Published: 2013

Journal Articles

Proteasome Activity Not M-Protein Production Influences Multiple Myeloma (MM) Responsiveness to Bortezomib (BZB): The Key Role of PSMB5 ,

Ping Zhou, MD, PhD, Xun Ma, Raymond L. Comenzo, MD

Blood (2011) 118 (21): 3491.

DOI: https://doi.org/10.1182/blood.V118.21.3491.3491

Published: 2011

Journal Articles

Validation of a Human Acute Lymphoblastic Leukemia Mouse Model Using Next Generation RNA Sequencing,

Noriko Satake, MD, Sheila Thampi, Clifford Tepper, Astra Chang, Ping Zhou, Bridget McLaughlin, PhD, Jeannine McGee, Jan A. Nolta, PhD

Blood (2011) 118 (21): 3576.

DOI: https://doi.org/10.1182/blood.V118.21.3576.3576

Published: 2011

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NARROW

The Pattern of Organ Responses Varies in Patients with Systemic Light-Chain Amyloidosis and Heart or Kidney or Heart and Kidney Involvement Who Achieve Deep Hematologic Responses

Results from a Phase 2 Study of a Novel Janus Kinase Inhibitor in Treatment of Patients with Myelofibrosis

Therapeutic Activity of Combining BCL-2 and HMG-CoA Reductase Inhibition in Systemic Light-Chain Amyloidosis

Risk and Prognostic Factors for Intracranial Hemorrhage in Elderly Patients with Immune Thrombocytopenia

In Systemic Light-Chain Amyloidosis Complete and Very Good Partial Responses Are Not Enough: Involved Free Light Chain (iFLC) Levels < 10mg/L Are Associated with Optimal Long-Term Survival

B-Cell Maturation Antigen (BCMA) in Systemic Light-Chain Amyloidosis (AL): Association with Disease Activity and Its Modulation with Gamma-Secretase Inhibition

Seeking AL Amyloidosis Very Early: The SAVE Trial — Identifying Clonal Lambda Light Chain Genes in Patients with MGUS or Smoldering Multiple Myeloma

Potential Long-Term Treatment of Hemophilia a By Early Postnatal Co-Transplantation of Cord Blood Derived Endothelial Colony-Forming Cells and Placental Mesenchymal Stem Cells

Senescent CD8+ T Cells in Myeloma Patients: Implications for Cellular Therapies

Effective Lipidoid Nanoparticle Delivery In Vivo of siRNA Targeting Kappa Light Chain Production in a Murine Xenograft Model

Identifying a Murine Xenograft Model Relevant to Light-Chain Specific Approaches to Human Ig Light-Chain Diseases

Daratumumab Activity Is Agnostic to Fc Gamma Receptor 3A (FcγR3A) 158 Genotype in Patients with Primary Refractory or Relapsed Systemic AL Amyloidosis

Alu-Element Insertion in Pklr Gene As a Novel Cause of Severe Hereditary Nonspherocytic Hemolytic Anemia

Cytokinesis failure in RhoA-deficient mouse erythroblasts involves actomyosin and midbody dysregulation and triggers p53 activation

siRNA for the Ig Light Chain Constant Region Reduces Light Chain Production and Secretion By Human Plasma Cells and in a Murine Xenograft Model

One siRNA pool targeting the λ constant region stops λ light-chain production and causes terminal endoplasmic reticulum stress

RhoA Gtpase Regulates Erythroblast Cytokinesis and Enucleation By Dynamic Coordination Of The Microtubule-Actomyosin Machineries For Successful Abscission

Acute Lymphoblastic Leukemia Is a Bcl-2 Dependent Disease: Proteomic Profiling and Pre-Clinical Efficacy Of a Selective Bcl-2 Antagonist ABT-199

Proteasome Activity Not M-Protein Production Influences Multiple Myeloma (MM) Responsiveness to Bortezomib (BZB): The Key Role of PSMB5 ,

Validation of a Human Acute Lymphoblastic Leukemia Mouse Model Using Next Generation RNA Sequencing,

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American Society of Hematology

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American Society of Hematology

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