Search Results | Blood | American Society of Hematology

1-20 of 102

2 3 4 5

Sort by

Sort Order Select

Journal Articles

Prophylactic tranexamic acid in patients with hematologic malignancy: a placebo controlled, randomized clinical trial

Terry B Gernsheimer, Siobhan P Brown, Darrell J Triulzi, Nigel S Key, Nahed El Kassar, Heather Herren, Jacqueline N Poston, Michael Boyiadzis, Brandi N. Reeves, Subodh Selukar, Monica B Pagano, Scott S Emerson, Susanne May

Blood blood.2022016308.

DOI: https://doi.org/10.1182/blood.2022016308

Published: 2022

Includes: Supplemental data

Journal Articles

Relationship between Endogenous, Transgene FVIII Expression and Bleeding Events Following Valoctocogene Roxaparvovec Gene Transfer for Severe Hemophilia A: A Post-Hoc Analysis of the GENEr8-1 Phase 3 Trial

Blood (2021) 138 (Supplement 1): 3972.

DOI: https://doi.org/10.1182/blood-2021-144508

Published: 2021

Journal Articles

Emizicumab Promotes Factor Xa Generation on Activated Endothelium in a Blood Cell-Independent Manner

Patrick Ellsworth, Dougald Monroe, Maureane Hoffman, Nigel S Key

Blood (2021) 138 (Supplement 1): 3182.

DOI: https://doi.org/10.1182/blood-2021-148556

Published: 2021

Journal Articles

Absence of Hyperactivation of Fibrinolysis Explains the Lack of Hemostatic Efficacy of Prophylactic Tranexamic Acid (TXA) in Hypoproliferative Thrombocytopenia

Anton Ilich, Terry B. Gernsheimer, Darrell J Triulzi, Heather Herren, Siobhan P Brown, Lori A Holle, Andrew T Lucas, Nahed El Kassar, Alisa S. Wolberg, Susanne May, Nigel S Key

Blood (2021) 138 (Supplement 1): 2094.

DOI: https://doi.org/10.1182/blood-2021-146898

Published: 2021

Journal Articles

Cleavage of High Molecular Weight Kininogen and Bradykinin Release By Red Blood Cell Microvesicles As a Putative Mechanism for Hypotensive Transfusion Reactions

Michael W Henderson, Matthew Karafin, Anton Ilich, Nigel S Key

Blood (2021) 138 (Supplement 1): 3240.

DOI: https://doi.org/10.1182/blood-2021-152595

Published: 2021

Journal Articles

Rituximab Monotherapy Is Effective for Inhibitor Eradication with Concomitant Porcine Factor VIII Followed By Emicizumab for Bleed Control in Acquired Hemophilia a

Patrick Ellsworth, Sheh-Li Chen, Christopher Wang, Nigel S Key, Alice Ma

Blood (2021) 138 (Supplement 1): 348.

DOI: https://doi.org/10.1182/blood-2021-154207

Published: 2021

Journal Articles

Inhibition of Factor XII Attenuates Prothrombotic Complications in Sickle Cell Mice

Erica Sparkenbaugh, Christina M Abrams, Megan D Miller, Brian C Cooley, Anton Ilich, Shreya Yadav, Michael Wallisch, Nigel S Key, Andras Gruber, Felicity N. E. Gavins, Rafal Pawlinski

Blood (2021) 138 (Supplement 1): 189.

DOI: https://doi.org/10.1182/blood-2021-152753

Published: 2021

Journal Articles

Plasmin-mediated cleavage of high-molecular-weight kininogen contributes to acetaminophen-induced acute liver failure

Michael W. Henderson, Erica M. Sparkenbaugh, Shaobin Wang, Anton Ilich, Denis F. Noubouossie, Reiner Mailer, Thomas Renné, Matthew J. Flick, James P. Luyendyk, Zu-Lin Chen, Sidney Strickland, R. Todd Stravitz, Keith R. McCrae, Nigel S. Key, Rafal Pawlinski

Blood (2021) 138 (3): 259–272.

DOI: https://doi.org/10.1182/blood.2020006198

Published: 2021

Includes: Supplemental data

Journal Articles

First Data from the Phase 3 HOPE-B Gene Therapy Trial: Efficacy and Safety of Etranacogene Dezaparvovec (AAV5-Padua hFIX variant; AMT-061) in Adults with Severe or Moderate-Severe Hemophilia B Treated Irrespective of Pre-Existing Anti-Capsid Neutralizing Antibodies

Steven W. Pipe, MD, Michael Recht, MD PhD, Nigel S. Key, MD, Frank W.G. Leebeek, MD PhD, Giancarlo Castaman, MD, Susan U. Lattimore, R.N., Paul Van Der Valk, Kathelijne Peerlinck, MD PhD, Michiel Coppens, MD, Niamh O'Connell, MD PhD, John Pasi, MB, ChB, PhD FRCP, FRCPath, FRCPCH, Peter Kampmann, MD, Karina Meijer, MD PhD, Annette von Drygalski, MD Pharm D, Guy Young, MD, Cedric Hermans, MDMRCP,PhD, Jan Astermark, MD PhD, Robert Klamroth, MD PhD, Richard S. Lemons, MD, Nathan Visweshwar, MD, Shelley Crary, MD MS, Rashid Kazmi, MBBS, Emily Symington, Miguel A. Escobar, MD, Esteban Gomez, MD, Rebecca Kruse-Jarres, MD, Adam Kotowski, MD, Doris Quon, MD PhD, Michael Wang, MD, Allison P. Wheeler, MD, Eileen K Sawyer, PhD, Stephanie Verweij, BSc, Valerie Colletta, MSc, Naghmana Bajma, MD, Robert Gut, MD PhD, Wolfgang A. Miesbach, MD PhD

Blood (2020) 136 (Supplement_2): LBA-6.

DOI: https://doi.org/10.1182/blood-2020-143560

Published: 2020

Journal Articles

Thrombin-Induced Endothelial Cell Damage Is Mitigated By Human Anti-Thrombin III in a Microfluidic Device

William Wulftange, Erdem Kucukal, PhD, Yuncheng Man, Ran An, PhD, Karamoja Monchamp, Olabimpe Olayiwola, MS, Jane A. Little, MD, Nigel S. Key, MD, Umut A. Gurkan, PhD

Blood (2020) 136 (Supplement 1): 24–25.

DOI: https://doi.org/10.1182/blood-2020-141583

Published: 2020

Journal Articles

Etranacogene Dezaparvovec (AAV5-Padua hFIX variant), an Enhanced Vector for Gene Transfer in Adults with Severe or Moderate-Severe Hemophilia B: Two Year Data from a Phase 2b Trial

Annette von Drygalski, Adam Giermasz, MD PhD, Giancarlo Castaman, MD, Nigel S. Key, MD, Susan U. Lattimore, Frank W.G. Leebeek, MD PhD, Wolfgang A. Miesbach, MD, Michael Recht, MD PhD, Esteban Gomez, MD, Robert Gut, Steven W. Pipe, MD

Blood (2020) 136 (Supplement 1): 13.

DOI: https://doi.org/10.1182/blood-2020-139295

Published: 2020

Journal Articles

Effects of Tranexamic Acid Prophylaxis on Bleeding Outcomes in Hematologic Malignancy: The a-TREAT Trial

Terry B. Gernsheimer, MD, Siobhan P Brown, PhD, Darrell J Triulzi, MD, Nigel S. Key, MD, Nahed El Kassar, MD PhD, Heather Herren, RN, MPH, Susanne May, PhD

Blood (2020) 136 (Supplement 1): 1–2.

DOI: https://doi.org/10.1182/blood-2020-138920

Published: 2020

Journal Articles

Utility of Inferior Vena Cava Filter in the Management of Venous Thromboembolism Among Patients with Brain Metastases: A Population-Based Study

Vaibhav Kumar, MBBS,MS, Ann M Brunson, MS, Anjlee Mahajan, MD, Nigel S. Key, MD, Ted Wun, MD

Blood (2020) 136 (Supplement 1): 47–48.

DOI: https://doi.org/10.1182/blood-2020-138790

Published: 2020

Journal Articles

Venous Thromboembolism Incidence and Impact on Survival in Patients with Brain Metastases

Vaibhav Kumar, MBBS,MS, Xi Zhou, Benjamin Shiang Wu, MSc,PharmD, Joshua Herb, MD, Tzy-Mey Kuo, Laura Green, Chris D Baggett, PhD, Bradford Jackson, Nigel S. Key, MD, Jennifer L Lund, PhD, Katherine E Reeder-Hayes

Blood (2020) 136 (Supplement 1): 1.

DOI: https://doi.org/10.1182/blood-2020-136117

Published: 2020

Journal Articles

Thrombin activation of PAR-1 contributes to microvascular stasis in mouse models of sickle cell disease

Erica M. Sparkenbaugh, Chunsheng Chen, Tomasz Brzoska, Julia Nguyen, Shaobin Wang, Gregory M. Vercellotti, Nigel S. Key, Prithu Sundd, John D. Belcher, Rafal Pawlinski

Blood (2020) 135 (20): 1783–1787.

DOI: https://doi.org/10.1182/blood.2019003543

Published: 2020

Includes: Multimedia, Supplemental data

Journal Articles

Red blood cell microvesicles activate the contact system, leading to factor IX activation via 2 independent pathways

Denis F. Noubouossie, Michael W. Henderson, Micah Mooberry, Anton Ilich, Patrick Ellsworth, Mark Piegore, Sarah C. Skinner, Rafal Pawlinski, Ian Welsby, Thomas Renné, Maureane Hoffman, Dougald M. Monroe, Nigel S. Key

Blood (2020) 135 (10): 755–765.

DOI: https://doi.org/10.1182/blood.2019001643

Published: 2020

Includes: Supplemental data

Journal Articles

All-Cause and Inhibitor-Related Mortality in Non-Severe Hemophilia Α Patients in the United States

Ming Y. Lim, MBBChir,MA, Dunlei Cheng, PhD, Christine L. Kempton, MD MSc, Nigel S. Key, MBChB, FRCP

Blood (2019) 134 (Supplement_1): 902.

DOI: https://doi.org/10.1182/blood-2019-122991

Published: 2019

Journal Articles

Enhanced VTE Risk Stratification in Ambulatory Patients with Cancer

Joseph R. Shaw, MD, Ranjeeta Mallick, PhD MSc, BSc, Marc Carrier, MD, Anton Ilich, MD, Nigel S. Key, MBChB, FRCP, Philip S. Wells, MDMSc,FRCP

Blood (2019) 134 (Supplement_1): 634.

DOI: https://doi.org/10.1182/blood-2019-126306

Published: 2019

Journal Articles

High Molecular Weight Kininogen but Not Factor XII Deficiency Attenuates Acetaminophen-Induced Liver Injury in Mice

Michael Wayne Henderson, MSc, Erica Sparkenbaugh, PhD BS, Denis Noubouossie, MD PhD, Reiner Mailer, Thomas Renne, MD PhD, Keith R McCrae, MD, Nigel S. Key, MBChB, FRCP, Rafal Pawlinski, PhD

Blood (2019) 134 (Supplement_1): 3621.

DOI: https://doi.org/10.1182/blood-2019-127206

Published: 2019

Journal Articles

One Year Data from a Phase 2b Trial of AMT-061 (AAV5-Padua hFIX variant), an Enhanced Vector for Gene Transfer in Adults with Severe or Moderate-Severe Hemophilia B

Steven Pipe, MD, Adam Giermasz, MD PhD, Giancarlo Castaman, MD, Nigel S. Key, MBChB, FRCP, Susan U Lattimore, Frank Leebeek, MD PhD, Wolfgang Miesbach, MD PhD, Michael Recht, MD PhD, Esteban Gomez, MD, Alison Long, Robert Gut, Annette von Drygalski, MD PharmD

Blood (2019) 134 (Supplement_1): 3348.

DOI: https://doi.org/10.1182/blood-2019-128765

Published: 2019

2 3 4 5

NARROW

Prophylactic tranexamic acid in patients with hematologic malignancy: a placebo controlled, randomized clinical trial

Relationship between Endogenous, Transgene FVIII Expression and Bleeding Events Following Valoctocogene Roxaparvovec Gene Transfer for Severe Hemophilia A: A Post-Hoc Analysis of the GENEr8-1 Phase 3 Trial

Emizicumab Promotes Factor Xa Generation on Activated Endothelium in a Blood Cell-Independent Manner

Absence of Hyperactivation of Fibrinolysis Explains the Lack of Hemostatic Efficacy of Prophylactic Tranexamic Acid (TXA) in Hypoproliferative Thrombocytopenia

Cleavage of High Molecular Weight Kininogen and Bradykinin Release By Red Blood Cell Microvesicles As a Putative Mechanism for Hypotensive Transfusion Reactions

Rituximab Monotherapy Is Effective for Inhibitor Eradication with Concomitant Porcine Factor VIII Followed By Emicizumab for Bleed Control in Acquired Hemophilia a

Inhibition of Factor XII Attenuates Prothrombotic Complications in Sickle Cell Mice

Plasmin-mediated cleavage of high-molecular-weight kininogen contributes to acetaminophen-induced acute liver failure

First Data from the Phase 3 HOPE-B Gene Therapy Trial: Efficacy and Safety of Etranacogene Dezaparvovec (AAV5-Padua hFIX variant; AMT-061) in Adults with Severe or Moderate-Severe Hemophilia B Treated Irrespective of Pre-Existing Anti-Capsid Neutralizing Antibodies

Thrombin-Induced Endothelial Cell Damage Is Mitigated By Human Anti-Thrombin III in a Microfluidic Device

Etranacogene Dezaparvovec (AAV5-Padua hFIX variant), an Enhanced Vector for Gene Transfer in Adults with Severe or Moderate-Severe Hemophilia B: Two Year Data from a Phase 2b Trial

Effects of Tranexamic Acid Prophylaxis on Bleeding Outcomes in Hematologic Malignancy: The a-TREAT Trial

Utility of Inferior Vena Cava Filter in the Management of Venous Thromboembolism Among Patients with Brain Metastases: A Population-Based Study

Venous Thromboembolism Incidence and Impact on Survival in Patients with Brain Metastases

Thrombin activation of PAR-1 contributes to microvascular stasis in mouse models of sickle cell disease

Red blood cell microvesicles activate the contact system, leading to factor IX activation via 2 independent pathways

All-Cause and Inhibitor-Related Mortality in Non-Severe Hemophilia Α Patients in the United States

Enhanced VTE Risk Stratification in Ambulatory Patients with Cancer

High Molecular Weight Kininogen but Not Factor XII Deficiency Attenuates Acetaminophen-Induced Liver Injury in Mice

One Year Data from a Phase 2b Trial of AMT-061 (AAV5-Padua hFIX variant), an Enhanced Vector for Gene Transfer in Adults with Severe or Moderate-Severe Hemophilia B

Email alerts

ASH Publications

American Society of Hematology

Email alerts

ASH Publications

American Society of Hematology

This Feature Is Available To Subscribers Only