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Mukesh K. Jain
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Journal Articles

Nanoparticle-Directed Targeting of Clustered PSGL-1 Mitigates Neutrophil-Derived Thrombosis in Antiphospholipid Antibody Syndrome

David R Sweet, Asha Thomas, PhD, Stephanie D Lapping, MS, Kenneth A Kalikasingh, Thomas L. Ortel, MD PhD, Mukesh K Jain, MD, Andrei Maiseyeu, Lalitha V. Nayak, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 14–15.
DOI: https://doi.org/10.1182/blood-2020-139543
Published: 2020
Journal Articles

An ATF6-tPA pathway in hepatocytes contributes to systemic fibrinolysis and is repressed by DACH1

Ze Zheng, Lalitha Nayak, Wei Wang, Arif Yurdagul, Jr, Xiaobo Wang, Bishuang Cai, Stephanie Lapping, Lale Ozcan, Rajasekhar Ramakrishnan, Richard G. Pestell, Mukesh K. Jain, Ira Tabas
Journal: Blood
Blood (2019) 133 (7): 743–753.
DOI: https://doi.org/10.1182/blood-2018-07-864843
Published: 2019
Includes: Supplemental data
Journal Articles

The thromboprotective effect of bortezomib is dependent on the transcription factor Kruppel-like factor 2 ( KLF2 )

Brief Report
Lalitha Nayak, Hong Shi, G. Brandon Atkins, Zhiyong Lin, Alvin H. Schmaier, Mukesh K. Jain
Journal: Blood
Blood (2014) 123 (24): 3828–3831.
DOI: https://doi.org/10.1182/blood-2014-01-547448
Published: 2014
Includes: Supplemental data
Journal Articles

Prolylcarboxypeptidase promotes angiogenesis and vascular repair

Gregory N. Adams, Evi X. Stavrou, Chao Fang, Alona Merkulova, M. Amer Alaiti, Kohsuke Nakajima, Toshifumi Morooka, Sergei Merkulov, Gretchen A. LaRusch, Daniel I Simon, Mukesh K. Jain, Alvin H. Schmaier
Journal: Blood
Blood (2013) 122 (8): 1522–1531.
DOI: https://doi.org/10.1182/blood-2012-10-460360
Published: 2013
Includes: Supplemental data
Journal Articles

Impaired T-cell responses to sphingosine-1-phosphate in HIV-1 infected lymph nodes

Joseph C. Mudd, Patrick Murphy, Maura Manion, Robert Debernardo, Jeffrey Hardacre, John Ammori, Gareth A. Hardy, Clifford V. Harding, Ganapati H. Mahabaleshwar, Mukesh K. Jain, Jeffrey M. Jacobson, Ari D. Brooks, Sharon Lewis, Timothy W. Schacker, Jodi Anderson, Elias K. Haddad, Rafael A. Cubas, Benigno Rodriguez, Scott F. Sieg, Michael M. Lederman
Journal: Blood
Blood (2013) 121 (15): 2914–2922.
DOI: https://doi.org/10.1182/blood-2012-07-445783
Published: 2013
Includes: Supplemental data
Journal Articles

KLF2 and KLF4 Are Essential Mediators of the Anti-Thrombotic Effects of Statins in the Presence of Antiphospholipid/Anti-ß 2 GPI Antibodies,

Kristi L Allen, Ph.D., Mukesh K Jain, MD, Keith R. McCrae, MD
Journal: Blood
Blood (2011) 118 (21): 3272.
DOI: https://doi.org/10.1182/blood.V118.21.3272.3272
Published: 2011
Journal Articles

Angiogenesis: the HETE is on

Lalitha Nayak, Mukesh K. Jain
Journal: Blood
Blood (2011) 118 (20): 5367–5369.
DOI: https://doi.org/10.1182/blood-2011-09-376152
Published: 2011
Journal Articles

Endothelial cell activation by antiphospholipid antibodies is modulated by Krüppel-like transcription factors

Kristi L. Allen, Anne Hamik, Mukesh K. Jain, Keith R. McCrae
Journal: Blood
Blood (2011) 117 (23): 6383–6391.
DOI: https://doi.org/10.1182/blood-2010-10-313072
Published: 2011
Includes: Supplemental data
Journal Articles

Murine prolylcarboxypeptidase depletion induces vascular dysfunction with hypertension and faster arterial thrombosis

Gregory N. Adams, Gretchen A. LaRusch, Evi Stavrou, Yihua Zhou, Marvin T. Nieman, Gretta H. Jacobs, Yingjie Cui, Yuan Lu, Mukesh K. Jain, Fakhri Mahdi, Zia Shariat-Madar, Yoshio Okada, Louis G. D'Alecy, Alvin H. Schmaier
Journal: Blood
Blood (2011) 117 (14): 3929–3937.
DOI: https://doi.org/10.1182/blood-2010-11-318527
Published: 2011
Includes: Supplemental data
Journal Articles

Decreased Expression of KLF2 and KLF4 Induced by Antiphospholipid Antibodies Promotes NF-Kb-Mediated Endothelial Cell Activation and Is Modulated by CBP/p300

Kristi L Allen, Ph.D., Mukesh K Jain, M.D., Keith R McCrae, M.D.
Journal: Blood
Blood (2010) 116 (21): 4315.
DOI: https://doi.org/10.1182/blood.V116.21.4315.4315
Published: 2010
Journal Articles

Prolylcarboxypeptidase Deficiency Is a Risk Factor for Arterial Thrombosis and Hypertension

Gregory Adams, Gretchen LaRusch, Evi Stavrou, MD, Yihua Zhou, Marvin T. Nieman, PhD, Gretta Jacobs, Yingjie Cui, Yuan Lu, Mukesh K Jain, M.D., Fakhri Mahdi, MD, Zia Shariat-Madar, Louis G D'Alecy, Alvin H. Schmaier, MD
Journal: Blood
Blood (2010) 116 (21): 651.
DOI: https://doi.org/10.1182/blood.V116.21.651.651
Published: 2010
Journal Articles

Shear stress: devil's in the details

Anne Hamik, Mukesh K. Jain
Journal: Blood
Blood (2010) 116 (15): 2625–2626.
DOI: https://doi.org/10.1182/blood-2010-07-293472
Published: 2010
Journal Articles

PLDing a case for angiogenesis

Anne Hamik, Mukesh K. Jain
Journal: Blood
Blood (2010) 116 (8): 1194–1196.
DOI: https://doi.org/10.1182/blood-2010-05-284117
Published: 2010
Journal Articles

Fluid shear stress stimulates phosphorylation-dependent nuclear export of HDAC5 and mediates expression of KLF2 and eNOS

Weiye Wang, Chang Hoon Ha, Bong Sook Jhun, Chelsea Wong, Mukesh K. Jain, Zheng-Gen Jin
Journal: Blood
Blood (2010) 115 (14): 2971–2979.
DOI: https://doi.org/10.1182/blood-2009-05-224824
Published: 2010
Includes: Supplemental data