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Journal Articles

Venetoclax and dexamethasone synergize with inotuzumab ozogamicin–induced DNA damage signaling in B-lineage ALL

Hanna Kirchhoff, Uemran Karsli, Caroline Schoenherr, Karin Battmer, Sergej Erschow, Steven R. Talbot, Doris Steinemann, Michael Heuser, Olaf Heidenreich, Denise Hilfiker-Kleiner, Arnold Ganser, Matthias Eder, Michaela Scherr

Blood (2021) 137 (19): 2657–2661.

https://doi.org/10.1182/blood.2020008544

Published: 2021

Includes: Supplemental data

Journal Articles

SLAMF7 in Primary Effusion Lymphoma, Target for Individualized Therapy?

Hilmar Quentmeier, PhD, Claudia Pommerenke, PhD, Wilhelm G Dirks, PhD, Vivien Hauer, Max Koeppel, PhD, Stefan Nagel, PhD, Michaela Scherr, PhD, Margarete Zaborski, Hans G. Drexler, MD PhD

Blood (2018) 132 (Supplement 1): 5300.

https://doi.org/10.1182/blood-2018-99-110054

Published: 2018

Journal Articles

Synergy between FLT3-ITD and p53 Haploinsufficiency or Loss in the Development of Acute Myeloid Leukemia

Zengkai Pan, MD PhD, Min Yang, Kezhi Huang, MD PhD, Guntram Buesche, MD, Gudrun Göhring, MD, Michaela Scherr, PhD, Matthias Gaestel, PhD, Matthias Eder, MD, Julia Skokowa, MDPhD, Jianfeng Zhou, PhD, Karl Welte, Li-Gen Liu, MD, Arnold Ganser, MD, Zhixiong Li, MD

Blood (2018) 132 (Supplement 1): 771.

https://doi.org/10.1182/blood-2018-99-110770

Published: 2018

Journal Articles

Optimized Induction of Mitochondrial Apoptosis By Combination Therapies with Venetoclax for Chemotherapy-Free Treatment of BCR-ABL + Acute Lymphoblastic Leukemia in Preclinical Models

Matthias Eder, MD, Hanna Kirchhoff, Karin Battmer, Katharina Wohlan, Melanie Ricke-Hoch, PhD, Sergej Erschow, Edward Law, PhD, Arnold Kloos, Michael Heuser, MD, Arnold Ganser, MD, Denise Hilfiker-Kleiner, PhD, Olaf Heidenreich, PhD, Michaela Scherr, PhD

Blood (2018) 132 (Supplement 1): 4025.

https://doi.org/10.1182/blood-2018-99-114463

Published: 2018

Journal Articles

Stable Silencing of RUNX1/ETO Induces Expression of a Shortened PU.1 Variant in t(8;21) Kasumi Cells

Matthias Eder, Caroline Schoenherr, Katharina Wohlan, Fabian Frömling, Denise Hilfiker-Kleiner, Arnold Ganser, MD, Michaela Scherr

Blood (2016) 128 (22): 2716.

https://doi.org/10.1182/blood.V128.22.2716.2716

Published: 2016

Journal Articles

The Novel FLT3-N676K Mutant Induces Acute Leukemia Independently of the Inv(16) Chimeric Gene CBFB-MYH11

Kezhi Huang, Min Yang, Zengkai Pan, Florian H. Heidel, MD, Michaela Scherr, PhD, Matthias Eder, MD, Thomas Fischer, MD, Guntram Buesche, MD, Nils von Neuhoff, PhD, Arnold Ganser, MD, Zhixiong Li, MD

Blood (2015) 126 (23): 1383.

https://doi.org/10.1182/blood.V126.23.1383.1383

Published: 2015

Journal Articles

Effective Treatment of Human CML By RNAi In Vivo in a Xenotransplantation Mouse Model

Blood (2015) 126 (23): 1261.

https://doi.org/10.1182/blood.V126.23.1261.1261

Published: 2015

Journal Articles

BCL6 Overexpression – Regulated By AhR/ARNT and Wild-Type MEF2B – Drives Expression of Germinal Center Markers MYBL1 and LMO2

Hilmar Quentmeier, PhD, Jie Ding, PhD, Willy Dirks, PhD, Stefan Ehrentraut, PhD, Robert Geffers, PhD, Rod AF MacLeod, PhD, Stefan Nagel, PhD, Michaela Scherr, Lea AI Vaas, PhD, Hans G Drexler, Prof. MD

Blood (2014) 124 (21): 865.

https://doi.org/10.1182/blood.V124.21.865.865

Published: 2014

Journal Articles

Mir∼17-92 Identifies BCL2 As a Therapeutic Target In BCR-ABL Positive B-Lineage Acute Lymphoblastic Leukemia

Matthias Eder, MD, Alex Elder, David Barzan, Karin Battmer, Simon Bomken, Melanie Ricke-Hoch, Anke Schröder, Letizia Venturini, Heike Pfeiffer, Helen J Blair, PhD, Josef Vormoor, MD, Oliver G. Ottmann, MD, Arnold Ganser, Andreas Pich, Denise Hilfiker-Kleiner, Olaf Heidenreich, PhD, Michaela Scherr

Blood (2013) 122 (21): 835.

https://doi.org/10.1182/blood.V122.21.835.835

Published: 2013

Journal Articles

T(8;9)(p22;p24)/PCM1-JAK2 Activates SOCS2 and SOCS3 Via STAT5

Stefan Ehrentraut, Stefan Nagel, PhD, Michaela Scherr, Bjoern Schneider, Hilmar Quentmeier, PhD, Robert Geffers, PhD, Monika Prochorec-Sobieszek, Rhett P Ketterling, MD, Ryan A Knudson, Andrew L. Feldman, MD, Marshall Kadin, Hans G. Drexler, MD, PhD, Roderick AF MacLeod

Blood (2012) 120 (21): 1567.

https://doi.org/10.1182/blood.V120.21.1567.1567

Published: 2012

Journal Articles

Modulation of Anthracycline-Induced Cytotoxicity by Targeting the Prenylated Prenylome in Myeloid Leukemia Cells

Michael A Morgan, PhD, Fredrick O Onono, Peter H Spielmann, Thangaiah Subramanian, Michaela Scherr, Letizia Venturinin, Iris Dallmann, Arnold Ganser, MD, Christoph W.M. Reuter

Blood (2011) 118 (21): 1418.

https://doi.org/10.1182/blood.V118.21.1418.1418

Published: 2011

Journal Articles

Function of STAT5 Isoforms in Bcr-Abl Positive Cells

Michael Schaller-Schoenitz, Iris Dallmann, Arnold Ganser, MD, Michaela Scherr, Matthias Eder, MD

Blood (2011) 118 (21): 1313.

https://doi.org/10.1182/blood.V118.21.1313.1313

Published: 2011

Journal Articles

Enforced expression of miR-125b affects myelopoiesis by targeting multiple signaling pathways

Ewa Surdziel, Maciej Cabanski, Iris Dallmann, Marcin Lyszkiewicz, Andreas Krueger, Arnold Ganser, Michaela Scherr, Matthias Eder

Blood (2011) 117 (16): 4338–4348.

https://doi.org/10.1182/blood-2010-06-289058

Published: 2011

Includes: Supplemental data

Journal Articles

Enforced Expression of Mir-125b Blocks Granulocytic Differentiation by Simultaneous Repression of Multiple Targets.

Ewa Surdziel, Maciej Cabanski, Iris Dallmann, Arnold Ganser, Michaela Scherr, Matthias Eder

Blood (2010) 116 (21): 1554.

https://doi.org/10.1182/blood.V116.21.1554.1554

Published: 2010

Journal Articles

Activation of Paired-Homeobox Gene PITX1 by Del(5)(q31) In T-Cell Acute Lymphoblastic Leukemia (T-ALL)

Stefan Nagel, PhD, Letizia Venturini, PhD, Grzegorz K. Przybylski, MD, Piotr Grabarczyk, PhD, Björn Schneider, PhD, Corinna Meyer, Maren Kaufmann, Christian A. Schmidt, MD, Michaela Scherr, PhD, Hans G. Drexler, MD, PhD, Roderick AF MacLeod, PhD

Blood (2010) 116 (21): 4644.

https://doi.org/10.1182/blood.V116.21.4644.4644

Published: 2010

Journal Articles

Transcriptional Regulation of Oncogenic MEF2C In T-Cell Acute Lymphoblastic Leukemia (T-ALL).

Stefan Nagel, PhD, Letizia Venturini, PhD, Corinna Meyer, Maren Kaufmann, Michaela Scherr, PhD, Hans G. Drexler, MD, PhD, Roderick AF MacLeod, PhD

Blood (2010) 116 (21): 3636.

https://doi.org/10.1182/blood.V116.21.3636.3636

Published: 2010

Journal Articles

Hypomethylation of Tumor Suppressor Genes in Acute Myeloid Leukemia: Characteristic of Cell Lines with MLL Abnormalities?.

Hilmar Quentmeier, Sonja Röhrs, Wilhelm G Dirks, Claus Meyer, Rolf Marschalek, Michaela Scherr, Robert K. Slany, PhD, Andrew Wallace, Hans G. Drexler

Blood (2009) 114 (22): 365.

https://doi.org/10.1182/blood.V114.22.365.365

Published: 2009

Journal Articles

A Novel Proteomic Approach to Define Leukemia Cell Resistance to Farnesyltransferase Inhibitors.

Fredrick O. Onono, Ph.D., Michael A. Morgan, Ph.D., H. Peter Spielmann, Ph.D., Douglas A Andres, Ph.D., Michaela Scherr, Ph.D., Letizia Venturini, Ph.D., Iris Dallman, Arnold Ganser, MD, Christoph WM Reuter, M.D., Ph.D.

Blood (2009) 114 (22): 3761.

https://doi.org/10.1182/blood.V114.22.3761.3761

Published: 2009

Journal Articles

Polycomb Repressor Complex 2 Regulates HOXA9 and HOXA10, Activating ID2 in NK/T-Cell Lines.

Stefan Nagel, Letizia Venturini, Marquez E. Victor, Corinna Meyer, Maren Kaufmann, Michaela Scherr, Roderick A.F. MacLeod, Hans G. Drexler

Blood (2009) 114 (22): 1281.

https://doi.org/10.1182/blood.V114.22.1281.1281

Published: 2009

Journal Articles

NK-Like Homeodomain Proteins Regulate NOTCH3-Signaling in T-Cells.

Stefan Nagel, PhD, Letizia Venturini, Grzegorz K. Przybylski, Piotr Grabarczyk, Corinna Meyer, Maren Kaufmann, Karin Battmer, Christian A. Schmidt, Hans G. Drexler, Michaela Scherr, Roderick A.F. MacLeod

Blood (2008) 112 (11): 1194.

https://doi.org/10.1182/blood.V112.11.1194.1194

Published: 2008

NARROW

Venetoclax and dexamethasone synergize with inotuzumab ozogamicin–induced DNA damage signaling in B-lineage ALL

SLAMF7 in Primary Effusion Lymphoma, Target for Individualized Therapy?

Synergy between FLT3-ITD and p53 Haploinsufficiency or Loss in the Development of Acute Myeloid Leukemia

Optimized Induction of Mitochondrial Apoptosis By Combination Therapies with Venetoclax for Chemotherapy-Free Treatment of BCR-ABL + Acute Lymphoblastic Leukemia in Preclinical Models

Stable Silencing of RUNX1/ETO Induces Expression of a Shortened PU.1 Variant in t(8;21) Kasumi Cells

The Novel FLT3-N676K Mutant Induces Acute Leukemia Independently of the Inv(16) Chimeric Gene CBFB-MYH11

Effective Treatment of Human CML By RNAi In Vivo in a Xenotransplantation Mouse Model

BCL6 Overexpression – Regulated By AhR/ARNT and Wild-Type MEF2B – Drives Expression of Germinal Center Markers MYBL1 and LMO2

Mir∼17-92 Identifies BCL2 As a Therapeutic Target In BCR-ABL Positive B-Lineage Acute Lymphoblastic Leukemia

T(8;9)(p22;p24)/PCM1-JAK2 Activates SOCS2 and SOCS3 Via STAT5

Modulation of Anthracycline-Induced Cytotoxicity by Targeting the Prenylated Prenylome in Myeloid Leukemia Cells

Function of STAT5 Isoforms in Bcr-Abl Positive Cells

Enforced expression of miR-125b affects myelopoiesis by targeting multiple signaling pathways

Enforced Expression of Mir-125b Blocks Granulocytic Differentiation by Simultaneous Repression of Multiple Targets.

Activation of Paired-Homeobox Gene PITX1 by Del(5)(q31) In T-Cell Acute Lymphoblastic Leukemia (T-ALL)

Transcriptional Regulation of Oncogenic MEF2C In T-Cell Acute Lymphoblastic Leukemia (T-ALL).

Hypomethylation of Tumor Suppressor Genes in Acute Myeloid Leukemia: Characteristic of Cell Lines with MLL Abnormalities?.

A Novel Proteomic Approach to Define Leukemia Cell Resistance to Farnesyltransferase Inhibitors.

Polycomb Repressor Complex 2 Regulates HOXA9 and HOXA10, Activating ID2 in NK/T-Cell Lines.

NK-Like Homeodomain Proteins Regulate NOTCH3-Signaling in T-Cells.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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