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Mazyar Shadman
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Journal Articles

Impact of CD19 CAR T-cell product type on outcomes in relapsed or refractory aggressive B-NHL

Clinical Trials & Observations
Jordan Gauthier, Nicolas Gazeau, Alexandre V. Hirayama, Joshua A. Hill, Vicky Wu, Aisling Cearley, Paula Perkins, Angela Kirk, Mazyar Shadman, Victor A. Chow, Ajay K. Gopal, Alexandria Hodges Dwinal, Staci Williamson, Jessie Myers, Andy Chen, Sarah Nagle, Brandon Hayes-Lattin, Levanto Schachter, David G. Maloney, Cameron J. Turtle, Mohamed L. Sorror, Richard T. Maziarz
Journal: Blood
Blood (2022) 139 (26): 3722–3731.
DOI: https://doi.org/10.1182/blood.2021014497
Published: 2022
Includes: Supplemental data
Journal Articles

Autologous transplant vs chimeric antigen receptor T-cell therapy for relapsed DLBCL in partial remission

Mazyar Shadman, Marcelo Pasquini, Kwang Woo Ahn, Yue Chen, Cameron J. Turtle, Peiman Hematti, Jonathon B. Cohen, Farhad Khimani, Siddhartha Ganguly, Reid W. Merryman, Jean A. Yared, Frederick L. Locke, Nausheen Ahmed, Pashna N. Munshi, Amer Beitinjaneh, Patrick M. Reagan, Alex F. Herrera, Craig S. Sauter, Mohamed A. Kharfan-Dabaja, Mehdi Hamadani
Journal: Blood
Blood (2022) 139 (9): 1330–1339.
DOI: https://doi.org/10.1182/blood.2021013289
Published: 2022
Includes: Supplemental data
Journal Articles

Analysis of Outcomes and Predictors of Response in Patients with Relapsed Mantle Cell Lymphoma Treated with Brexucabtagene Autoleucel

Jason T. Romancik, Subir Goyal, James N Gerson, Hatcher J Ballard, Yazeed Sawalha, David A. Bond, Michael Joseph Rogalski, Irl Brian Greenwell, Koen van Besien, Samuel Yamshon, Reem Karmali, Imran Nizamuddin, Pallawi Torka, Victor A. Chow, Mazyar Shadman, Nilanjan Ghosh, Tamara K. Moyo, Timothy S. Fenske, Alexandra Rezazadeh, Natalie S Grover, Kami J. Maddocks, Caron Jacobson, Jonathon B. Cohen
Journal: Blood
Blood (2021) 138 (Supplement 1): 1756.
DOI: https://doi.org/10.1182/blood-2021-153277
Published: 2021
Journal Articles

Safety and Efficacy of Two Anakinra Dose Regimens for Refractory CRS or Icans after CAR T-Cell Therapy

Nicolas Gazeau, Pere Barba, Gloria Iacoboni, Mi Kwon, Rebeca Bailen, Juan Luis Reguera, Lucía López Corral, Rafael Hernani, Valentín Ortiz-Maldonado, Antonio Perez-Martinez, Richard T. Maziarz, Staci Williamson, Eneida R. Nemecek, Mazyar Shadman, Andrew Coman, Damian J. Green, Victor A. Chow, Alexandre V. Hirayama, David G. Maloney, Cameron J. Turtle, Jordan Gauthier
Journal: Blood
Blood (2021) 138 (Supplement 1): 2816.
DOI: https://doi.org/10.1182/blood-2021-147454
Published: 2021
Journal Articles

Safety and Efficacy of Third Generation CD20 Targeted CAR-T (MB-106) for Treatment of Relapsed/Refractory B-NHL and CLL

Mazyar Shadman, Cecilia Yeung, Mary Redman, Sang Yun Lee, Dong Hoon Lee, Susan Ra, Chaitra S. Ujjani, Bruce J. Dezube, Christina Poh, Edus H. Warren, Aude G. Chapuis, Damian J. Green, Andrew J. Cowan, Ryan D. Cassaday, Hans-Peter Kiem, Jordan Gauthier, Cameron J. Turtle, Ryan C. Lynch, Stephen D. Smith, Ajay K Gopal, David G. Maloney, Brian G. Till
Journal: Blood
Blood (2021) 138 (Supplement 1): 3872.
DOI: https://doi.org/10.1182/blood-2021-149181
Published: 2021
Journal Articles

Efficacy and Safety of Ublituximab in Combination with Umbralisib (U2) in Patients with Chronic Lymphocytic Leukemia (CLL) By Treatment Status: A Sub-Analysis of the Phase 3 Unity-CLL Study

Ryan Jacobs, Wojciech Jurczak, Ian W. Flinn, Sebastian Grosicki, Krzysztof Giannopoulos, Tomasz Wróbel, Syed F. Zafar, Jennifer L. Cultrera, Suman Kambhampati, Alexey V. Danilov, John M. Burke, Jerome Goldschmidt, Douglas F. Beach, Scott F. Huntington, Javier Pinilla Ibarz, Jeff P. Sharman, Tanya Siddiqi, Danielle M. Brander, Mazyar Shadman, John M. Pagel, Monika Dlugosz-Danecka, Nilanjan Ghosh, Kathryn S. Kolibaba, Peter Sportelli, Hari P. Miskin, Owen A. O'Connor, Michael S. Weiss, John G. Gribben
Journal: Blood
Blood (2021) 138 (Supplement 1): 3726.
DOI: https://doi.org/10.1182/blood-2021-147460
Published: 2021
Journal Articles

Addressing a New Challenge in Chronic Lymphocytic Leukemia: Outcomes of Therapies after Exposure to Both a Covalent Bruton's Tyrosine Kinase Inhibitor and Venetoclax

Meghan C. Thompson, Lindsey E. Roeker, Catherine C. Coombs, Jeffrey L. Jensen, Manali Kamdar, Alan Skarbnik, John M. Pagel, Neil Bailey, Jeffrey J. Pu, Ryan Jacobs, Brian T. Hill, Danielle M. Brander, Mazyar Shadman, Chaitra S. Ujjani, Kristen E. Battiato, Celina J. Komari, Guilherme Sacchi De Camargo Correia, Julia H. Aronson, Joanna M Rhodes, Paola Ghione, Bita Fakhri, Paul M. Barr, Craig A. Portell, Nicole Lamanna, Javier Pinilla-Ibarz, Andrew D. Zelenetz, Stephen J Schuster, John N. Allan, Toby A. Eyre, Anthony R. Mato
Journal: Blood
Blood (2021) 138 (Supplement 1): 2628.
DOI: https://doi.org/10.1182/blood-2021-150751
Published: 2021
Journal Articles

Randomized, Phase III Study of Early Intervention with Venetoclax and Obinutuzumab Versus Delayed Therapy with Venetoclax and Obinutuzumab in Newly Diagnosed Asymptomatic High-Risk Patients with Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL): Evolve CLL/SLL Study (SWOG S1925; NCT#04269902)

Deborah M. Stephens, Anna Moseley, Brian T. Hill, John M. Pagel, Mazyar Shadman, Michael Fisch, Alexey V. Danilov, David Ng, Anthony R. Mato, Danielle M. Brander, Megan Othus, Steven Coutre, Susan M. O'Brien, Harry P. Erba
Journal: Blood
Blood (2021) 138 (Supplement 1): 2630.
DOI: https://doi.org/10.1182/blood-2021-144780
Published: 2021
Journal Articles

Chronic Lymphocytic Leukemia Comorbidity Index (CLL-CI), a Novel Comorbidity Measure, Predicts Outcomes in the Context of Targeted Agents and in a Large National Registry

Max J. Gordon, Andy Kaempf, Emelie Rotbain, Andrea Sitlinger, Geoffrey Shouse, Matthew Mei, Danielle M. Brander, Tareq Salous, Brian T. Hill, Michael Choi, Jonathon B. Cohen, Deborah M. Stephens, Dan O. Persky, Krish Patel, Mazyar Shadman, Byung Park, Carsten Utoft Niemann, Alexey V. Danilov
Journal: Blood
Blood (2021) 138 (Supplement 1): 2637.
DOI: https://doi.org/10.1182/blood-2021-148253
Published: 2021
Journal Articles

Impact of Comorbidities on Outcomes and Toxicity in Patients Treated with CAR T-Cell Therapy for Diffuse Large B Cell Lymphoma (DLBCL): A Multicenter Rwe Study

Geoffrey Shouse, Andy Kaempf, David Yashar, Audrey M. Sigmund, Gordon Smilnak, Steven M. Bair, Agrima Mian, Lindsey Fitzgerald, Amneet Bajwa, Samantha Jaglowski, Neil Bailey, Mazyar Shadman, Krish Patel, Deborah M. Stephens, Manali Kamdar, Brian T. Hill, Jordan Gauthier, Reem Karmali, Adam S Kittai, Alexey V. Danilov
Journal: Blood
Blood (2021) 138 (Supplement 1): 529.
DOI: https://doi.org/10.1182/blood-2021-149735
Published: 2021
Journal Articles

Safety and Efficacy of Fully Human BCMA CAR T Cells in Combination with a Gamma Secretase Inhibitor to Increase BCMA Surface Expression in Patients with Relapsed or Refractory Multiple Myeloma

Andrew J. Cowan, Margot Pont, Blythe Duke Sather, Cameron J. Turtle, Brian G. Till, Edward Libby, David G. Coffey, Sherilyn A. Tuazon, Brent L. Wood, Ted A Gooley, Qian Vicky Wu, Mazyar Shadman, Jordan Gauthier, Aude G. Chapuis, Filippo Milano, David G. Maloney, Stanley R. Riddell, Damian J. Green
Journal: Blood
Blood (2021) 138 (Supplement 1): 551.
DOI: https://doi.org/10.1182/blood-2021-154170
Published: 2021
Journal Articles

Phase 2 Study of Zanubrutinib in BTK Inhibitor-Intolerant Patients (Pts) with Relapsed/Refractory B-Cell Malignancies

Mazyar Shadman, Ian W. Flinn, Moshe Y. Levy, Ryan Porter, John M. Burke, Jennifer L. Cultrera, Jamal Misleh, Syed F. Zafar, Benjamin Freeman, Subramanya S. Rao, Habte Yimer, Arvind Chaudhry, Mitul D. Gandhi, Troy H. Guthrie, Edwin Kingsley, Praveen K. Tumula, Sudhir Manda, Dih-Yih Chen, Aileen Cohen, Kunthel By, Linlin Xu, Ye Liu, Jeff P. Sharman
Journal: Blood
Blood (2021) 138 (Supplement 1): 1410.
DOI: https://doi.org/10.1182/blood-2021-148544
Published: 2021
Journal Articles

Oral Ixazomib in Untreated Follicular Lymphoma Permits COVID-19 Vaccine Response and Its Efficacy Is Associated with Clinical Factors and Gene Expression Signatures

Solomon A. Graf, Ryan C. Lynch, Chaitra S. Ujjani, Ted A Gooley, David G. Coffey, Andrew J. Cowan, Stephen D. Smith, Mazyar Shadman, Edus H. Warren, Edward Libby, Colin D. Godwin, Alexander L Greninger, Jonathan R. Fromm, Ajay K Gopal
Journal: Blood
Blood (2021) 138 (Supplement 1): 1363.
DOI: https://doi.org/10.1182/blood-2021-153168
Published: 2021
Journal Articles

Concurrent Pembrolizumab with AVD for Untreated Classical Hodgkin Lymphoma

Ryan C. Lynch, Chaitra S. Ujjani, Christina Poh, Edus H. Warren, Stephen D. Smith, Mazyar Shadman, Andrei R Shustov, Brian G. Till, Yolanda D. Tseng, Hilary Coye, Megan Shelby, Susan Ottemiller, Hongyan Du, Jacquelin Vandermeer, Heather A. Rasmussen, Stefan Alig, Ash A. Alizadeh, Avanti Gulhane, Delphine Chen, Eric Wayne Dean, Jason Lukas, Paul S. Martin, Edmond A Marzbani, Jenna Voutsinas, Ajay K Gopal
Journal: Blood
Blood (2021) 138 (Supplement 1): 233.
DOI: https://doi.org/10.1182/blood-2021-144610
Published: 2021
Journal Articles

SEQUOIA: Results of a Phase 3 Randomized Study of Zanubrutinib versus Bendamustine + Rituximab (BR) in Patients with Treatment-Naïve (TN) Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)

Constantine S. Tam, Krzysztof Giannopoulos, Wojciech Jurczak, Martin Šimkovič, Mazyar Shadman, Anders Österborg, Luca Laurenti, Patricia Walker, Stephen Opat, Henry Chan, Hanna Ciepluch, Richard Greil, Monica Tani, Marek Trněný, Danielle M. Brander, Ian W. Flinn, Sebastian Grosicki, Emma Verner, Jennifer R. Brown, Brad S. Kahl, Paolo Ghia, Tian Tian, Carol Marimpietri, Jason C. Paik, Aileen Cohen, Jane Huang, Tadeusz Robak, Peter Hillmen
Journal: Blood
Blood (2021) 138 (Supplement 1): 396.
DOI: https://doi.org/10.1182/blood-2021-148457
Published: 2021
Journal Articles

COVID-19 in patients with CLL: improved survival outcomes and update on management strategies

Clinical Trials & Observations
Lindsey E. Roeker, Toby A. Eyre, Meghan C. Thompson, Nicole Lamanna, Alexander R. Coltoff, Matthew S. Davids, Peter O. Baker, Lori Leslie, Kerry A. Rogers, John N. Allan, Raul Cordoba, Alberto Lopez-Garcia, Darko Antic, John M. Pagel, Nicolas Martinez-Calle, José Antonio García-Marco, Jose‐Ángel Hernández‐Rivas, Fatima Miras, Catherine C. Coombs, Anders Österborg, Lotta Hansson, Amanda N. Seddon, Javier López Jiménez, Matthew R. Wilson, Dima El-Sharkawi, Daniel Wojenski, Shuo Ma, Talha Munir, Susana Valenciano, Erlene Seymour, Paul M. Barr, Jeffrey Pu, Piers E. M. Patten, Guilherme F. Perini, Scott F. Huntington, Helen Parry, Suchitra Sundaram, Alan Skarbnik, Manali Kamdar, Ryan Jacobs, Harriet Walter, Renata Walewska, Angus Broom, Sonia Lebowitz, Krista M. Isaac, Craig A. Portell, Inhye E. Ahn, Chaitra S. Ujjani, Mazyar Shadman, Sigrid S. Skånland, Elise A. Chong, Anthony R. Mato
Journal: Blood
Blood (2021) 138 (18): 1768–1773.
DOI: https://doi.org/10.1182/blood.2021011841
Published: 2021
Includes: Supplemental data
Journal Articles

Factors associated with outcomes after a second CD19-targeted CAR T-cell infusion for refractory B-cell malignancies

Clinical Trials & Observations
Jordan Gauthier, Evandro D. Bezerra, Alexandre V. Hirayama, Salvatore Fiorenza, Alyssa Sheih, Cassie K. Chou, Erik L. Kimble, Barbara S. Pender, Reed M. Hawkins, Aesha Vakil, Tinh-Doan Phi, Rachel N. Steinmetz, Abby W. Jamieson, Merav Bar, Ryan D. Cassaday, Aude G. Chapuis, Andrew J. Cowan, Damian J. Green, Hans-Peter Kiem, Filippo Milano, Mazyar Shadman, Brian G. Till, Stanley R. Riddell, David G. Maloney, Cameron J. Turtle
Journal: Blood
Blood (2021) 137 (3): 323–335.
DOI: https://doi.org/10.1182/blood.2020006770
Published: 2021
Includes: Supplemental data
Journal Articles

Vaccinations in CLL: implications for COVID-19

Clinical Trials & Observations
Mazyar Shadman, Chaitra Ujjani
Journal: Blood
Blood (2021) 137 (2): 144–146.
DOI: https://doi.org/10.1182/blood.2020009966
Published: 2021
Journal Articles

Efficacy and Safety of Zanubrutinib in Patients with Treatment-Naïve (TN) Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL) with del(17p): Follow-up Results from Arm C of the SEQUOIA (BGB-3111-304) Trial

Jennifer R. Brown, MD PhD, Tadeusz Robak, MDPhD, Paolo Ghia, MD PhD, Brad S. Kahl, MD, Patricia Walker, MBBS, BMedSci, FRACP, FRCPA, Wojciech Janowski, MBChB, FRCPA, FRACP, Henry Chan, MBChB, FRACP, FRCPA, Mazyar Shadman, MD MPH, Peter S. Ganly, BMBCh, PhD, Luca Laurenti, MD, Stephen Opat, MBBS (Hons), FRACP, FRCPA, Monica Tani, MD, Hanna Ciepluch, MD, Emma Verner, MBBS, BMedSci,FRCPA, FRACP, Martin Šimkovič, MD PhD, Anders Österborg, MD PhD, Marek Trněný, MD, Alessandra Tedeschi, MD, Piers Blombery, MBBS, Jason C. Paik, MD PhD, Fangfang Yin, PhD, Shibao Feng, PhD, Vanitha Ramakrishnan, PhD, Jane Huang, MD, Peter Hillmen, MBChB, PhD FRCP, FRCPath, Constantine S. Tam, MBBS, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 11–12.
DOI: https://doi.org/10.1182/blood-2020-134280
Published: 2020
Journal Articles

Third Generation CD20 Targeted CAR T-Cell Therapy (MB-106) for Treatment of Patients with Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma

Mazyar Shadman, MDMPH, Cecilia Yeung, MD, Mary W Redman, PhD, Sang Yun Lee, PhD, Dong Hoon Lee, B.S., Ajeetha Ramachandran, PhD, Susan Ra, BS, Edmond A Marzbani, MD, Solomon A. Graf, MD, Edus H. Warren, MD PhD, Ajay K. Gopal, MD, Aude G. Chapuis, MD, Merav Bar, Damian J. Green, MD, Jordan Gauthier, MD MSc, Ryan D. Cassaday, MD, Hans-Peter Kiem, MD PhD, Cameron J. Turtle, MBBS, PhD, David G. Maloney, MD PhD, Brian G. Till, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 38–39.
DOI: https://doi.org/10.1182/blood-2020-136440
Published: 2020