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Journal Articles

Proteomic and Phosphoproteomic Landscapes of Acute Myeloid Leukemia

Michael H Kramer, Qiang Zhang, Robert Sprung, Ryan B Day, Petra Erdmann-Gilmore, Yang Li, Ziheng Xu, Nichole M Helton, Daniel R George, Yiling Mi, Peter Westervelt, Jacqueline E Payton, Sai M Ramakrishnan, Christoper A Miller, Daniel C Link, John F. DiPersio, Matthew J Walter, R Reid Townsend, Timothy J Ley

Blood blood.2022016033.

DOI: https://doi.org/10.1182/blood.2022016033

Published: 2022

Includes: Supplemental data

Journal Articles

IL-1b expression in bone marrow dendritic cells is induced by TLR2 agonists and regulates HSC function

Sidan Li, Juo-Chin Yao, Karolyn A Oetjen, Joseph Ryan Krambs, Jun Xia, Jingzhu Zhang, Amy P Schmidt, Nichole M Helton, Robert S Fulton, Sharon E Heath, Isaiah R Turnbull, Gabriel Mbalaviele, Timothy J Ley, Matthew J Walter, Daniel C Link

Blood blood.2022016084.

DOI: https://doi.org/10.1182/blood.2022016084

Published: 2022

Includes: Supplemental data

Journal Articles

Inhibition of ATR with AZD6738 (Ceralasertib) for the Treatment of Progressive or Relapsed Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia: Safety and Preliminary Activity from a Phase Ib/II Study

Andrew M. Brunner, Yiwen Liu, Lourdes M. Mendez, Jacqueline S. Garcia, Philip C. Amrein, Donna S. Neuberg, Emma Dean, Simon Smith, Richard M. Stone, Amir T. Fathi, Matthew J. Walter, Timothy A. Graubert, Meagan A. Jacoby

Blood (2021) 138 (Supplement 1): 1521.

DOI: https://doi.org/10.1182/blood-2021-147301

Published: 2021

Journal Articles

Adverse Outcomes in Acute Myeloid Leukemia Are Associated with Tumor Cell-Mediated Immunosuppression

Blood (2021) 138 (Supplement 1): 800.

DOI: https://doi.org/10.1182/blood-2021-148645

Published: 2021

Journal Articles

Analysis of the Proteomes of Primary, De Novo Acute Myeloid Leukemia Cells from Adults

Michael H Kramer, Qiang Zhang, Robert W. Sprung, Petra Erdmann-Gilmore, Daniel R George, Nichole M Helton, Sharon E Heath, Jacqueline E. Payton, Peter Westervelt, Christopher A Miller, Matthew J. Walter, Daniel C. Link, John F. DiPersio, R Reid Townsend, Timothy J Ley

Blood (2021) 138 (Supplement 1): 3427.

DOI: https://doi.org/10.1182/blood-2021-148819

Published: 2021

Journal Articles

A Pilot Study of CPX-351 (Vyxeos © ) for Transplant Eligible, Higher Risk Patients with Myelodysplastic Syndrome

Meagan A. Jacoby, David A. Sallman, Bart L. Scott, Megan Haney, Fei Wan, John F. DiPersio, Ramzi Abboud, Keith E. Stockerl-Goldstein, Rami S. Komrokji, Mark A. Schroeder, Matthew J. Walter, Peter Westervelt, Geoffrey L. Uy

Blood (2021) 138 (Supplement 1): 540.

DOI: https://doi.org/10.1182/blood-2021-151137

Published: 2021

Journal Articles

Mutant TRP53-R172H Has Gain-of-Function or Dominant-Negative Effects in Response to Different Hematopoietic Stressors in Mice

Tanzir Ahmed, PhD, Tuoen Liu, MD PhD, Michael O. Alberti, MDPhD, Brian Wadugu, PhD, Matthew Ndonwi, PhD, Sarah Grieb, Matthew J. Walter, MD

Blood (2020) 136 (Supplement 1): 1.

DOI: https://doi.org/10.1182/blood-2020-141091

Published: 2020

Journal Articles

Signaling Gene Mutations Are Characterized By Diverse Patterns of Expansion and Contraction during Progression from MDS to Secondary AML

Andrew J Menssen, BA, Ajay Khanna, Christopher A Miller, PhD, Gue Su Chang, PhD, Jin J Shao, Sridhar Nonavinkere Srivatsan, MS, Joshua Robinson, Michelle O'Laughlin, Catrina Fronick, BS, Robert Fulton, MS, Kimberly J Brendel, Sharon E Heath, Peter Westervelt, MDPhD, John F. DiPersio, MD PhD, Daniel C. Link, MD, Meagan A. Jacoby, Eric Duncavage, MD, Timothy J Ley, MD, Matthew J. Walter, MD

Blood (2020) 136 (Supplement 1): 2–3.

DOI: https://doi.org/10.1182/blood-2020-140394

Published: 2020

Journal Articles

Creating a Variant Database for the American Society of Hematalogy By Consensus Variant Classification of Common Genes Associated with Hematologic Malignancies

Niroshan Nadarajah, Alex Wagner, PhD, Rafael Bejar, MD PhD, Mark Ewalt, MD, Annette S. Kim, MD, Michelle M. Le Beau, PhD, Xiaotu Ma, PhD, Manja Meggendorfer, PhD, Jamile M. Shammo, MD, Gabriella Ryan, Alexa J. Siddon, MD, David P. Steensma, MD, Matthew J. Walter, MD, Ahmet Zehir, PhD, Jinghui Zhang, PhD, Torsten Haferlach, MD

Blood (2020) 136 (Supplement 1): 4–5.

DOI: https://doi.org/10.1182/blood-2020-141204

Published: 2020

Journal Articles

Targeted Sequencing of 7 Genes Can Help Reduce Pathologic Misclassification of MDS

Blood (2020) 136 (Supplement 1): 32–33.

DOI: https://doi.org/10.1182/blood-2020-140317

Published: 2020

Journal Articles

SF3B1 -mutant MDS as a distinct disease subtype: a proposal from the International Working Group for the Prognosis of MDS

Blood (2020) 136 (2): 157–170.

DOI: https://doi.org/10.1182/blood.2020004850

Published: 2020

Journal Articles

Genetics of progression from MDS to secondary leukemia

Andrew J. Menssen, Matthew J. Walter

Blood (2020) 136 (1): 50–60.

DOI: https://doi.org/10.1182/blood.2019000942

Published: 2020

Journal Articles

Clonal Cytopenias of Undetermined Significance Are Common in Cytopenic Adults Evaluated for MDS in the National MDS Study

Blood (2019) 134 (Supplement_1): 4271.

DOI: https://doi.org/10.1182/blood-2019-126978

Published: 2019

Journal Articles

Mutant U2AF1 S34F and U2AF1 Q157P Induce Distinct RNA Splicing and Hematopoietic Phenotypes In Vivo

Michael O. Alberti, MD PhD, Meng'ou Zhu, BS, Sridhar Nonavinkere Srivatsan, MS, Tanzir Ahmed, PhD, Jin J. Shao, Brian Wadugu, BA, Cara Lunn Shirai, PhD, Matthew J. Walter, MD

Blood (2019) 134 (Supplement_1): 770.

DOI: https://doi.org/10.1182/blood-2019-123892

Published: 2019

Journal Articles

Improving Risk Assessment of AML with a Precision Genomic Strategy to Assess Mutation Clearance

Blood (2018) 132 (Supplement 1): 5277.

DOI: https://doi.org/10.1182/blood-2018-99-114979

Published: 2018

Journal Articles

The Role of Transcription Factor and Signaling Gene Mutations in the Clonal Evolution of MDS to Secondary AML

Andrew E Menssen, BA, Christopher A Miller, PhD, Ajay J Khanna, Gue Su Chang, PhD, Jin J Shao, Sridhar Nonavinkere Srivatsan, MS, Joshua Robinson, Kimberly J Brendel, Sharon E Heath, Eric J. Duncavage, MD, Matthew J. Walter, MD

Blood (2018) 132 (Supplement 1): 4338.

DOI: https://doi.org/10.1182/blood-2018-99-119798

Published: 2018

Journal Articles

Diagnosis of Myelodysplastic Syndromes and Related Conditions: Rates of Discordance between Local and Central Review in the NHLBI MDS Natural History Study

Ling Zhang, MD, Donald M Stablein, PhD, Pearlie Epling-Burnette, PhD PharmD, Alexandra M. Harrington, MDMT(ASCP), Lynn C. Moscinski, MD, Steven Kroft, MD, Amy E. DeZern, MD, Tareq Al Baghdadi, MD, Jane Jijun Liu, MD, Matthew J. Walter, MD, Rafael Bejar, MD PhD, Edward J. Gorak, DO, MBA, MS, Rami S. Komrokji, MD, Gregory A. Abel, MD MPH, Bart L Scott, MD, Steven D. Gore, MD, Mikkael A. Sekeres, MD MS

Blood (2018) 132 (Supplement 1): 4370.

DOI: https://doi.org/10.1182/blood-2018-99-116629

Published: 2018

Journal Articles

U2AF1(S34F) Mutant Hematopoietic Cells Require Expression of Wild-Type U2af1 for Survival

Brian Wadugu, BA, Amanda Heard, Joseph Bradley, BS, Matthew Ndonwi, PhD, Jin J Shao, Matthew J. Walter, MD

Blood (2018) 132 (Supplement 1): 941.

DOI: https://doi.org/10.1182/blood-2018-99-110836

Published: 2018

Journal Articles

Germ line tissues for optimal detection of somatic variants in myelodysplastic syndromes

Eric Padron, Markus C. Ball, Jamie K. Teer, Jeffrey S. Painter, Sean J. Yoder, Chaomei Zhang, Ling Zhang, Lynn C. Moscinski, Dana E. Rollison, Steven D. Gore, Rafael Bejar, Matthew J. Walter, Mikkael A. Sekeres, Rami S. Komrokji, Pearlie K. Epling-Burnette

Blood (2018) 131 (21): 2402–2405.

DOI: https://doi.org/10.1182/blood-2018-01-827881

Published: 2018

Includes: Supplemental data

Journal Articles

Loss of Toll-like receptor 2 results in accelerated leukemogenesis in the NUP98-HOXD13 mouse model of MDS

Darlene A. Monlish, Sima T. Bhatt, Eric J. Duncavage, Zev J. Greenberg, John L. Keller, Molly P. Romine, Wei Yang, Peter D. Aplan, Matthew J. Walter, Laura G. Schuettpelz

Blood (2018) 131 (9): 1032–1035.

DOI: https://doi.org/10.1182/blood-2017-08-801944

Published: 2018

Includes: Supplemental data

2 3 4 5

NARROW

Proteomic and Phosphoproteomic Landscapes of Acute Myeloid Leukemia

IL-1b expression in bone marrow dendritic cells is induced by TLR2 agonists and regulates HSC function

Inhibition of ATR with AZD6738 (Ceralasertib) for the Treatment of Progressive or Relapsed Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia: Safety and Preliminary Activity from a Phase Ib/II Study

Adverse Outcomes in Acute Myeloid Leukemia Are Associated with Tumor Cell-Mediated Immunosuppression

Analysis of the Proteomes of Primary, De Novo Acute Myeloid Leukemia Cells from Adults

A Pilot Study of CPX-351 (Vyxeos © ) for Transplant Eligible, Higher Risk Patients with Myelodysplastic Syndrome

Mutant TRP53-R172H Has Gain-of-Function or Dominant-Negative Effects in Response to Different Hematopoietic Stressors in Mice

Signaling Gene Mutations Are Characterized By Diverse Patterns of Expansion and Contraction during Progression from MDS to Secondary AML

Creating a Variant Database for the American Society of Hematalogy By Consensus Variant Classification of Common Genes Associated with Hematologic Malignancies

Targeted Sequencing of 7 Genes Can Help Reduce Pathologic Misclassification of MDS

SF3B1 -mutant MDS as a distinct disease subtype: a proposal from the International Working Group for the Prognosis of MDS

Genetics of progression from MDS to secondary leukemia

Clonal Cytopenias of Undetermined Significance Are Common in Cytopenic Adults Evaluated for MDS in the National MDS Study

Mutant U2AF1 S34F and U2AF1 Q157P Induce Distinct RNA Splicing and Hematopoietic Phenotypes In Vivo

Improving Risk Assessment of AML with a Precision Genomic Strategy to Assess Mutation Clearance

The Role of Transcription Factor and Signaling Gene Mutations in the Clonal Evolution of MDS to Secondary AML

Diagnosis of Myelodysplastic Syndromes and Related Conditions: Rates of Discordance between Local and Central Review in the NHLBI MDS Natural History Study

U2AF1(S34F) Mutant Hematopoietic Cells Require Expression of Wild-Type U2af1 for Survival

Germ line tissues for optimal detection of somatic variants in myelodysplastic syndromes

Loss of Toll-like receptor 2 results in accelerated leukemogenesis in the NUP98-HOXD13 mouse model of MDS

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American Society of Hematology

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American Society of Hematology

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