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Margot J. Pont
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Journal Articles

Single-cell analysis of the multiple myeloma microenvironment after γ-secretase inhibition and CAR T-cell therapy

David G. Coffey, Pinar Ataca Atilla, Erden Atilla, Ola Landgren, Andrew J. Cowan, Sylvain Simon, Margot J. Pont, Melissa L. Comstock, Geoffrey R. Hill, Stanley R. Riddell, Damian J. Green
Journal: Blood
Blood (2025) 145 (2): 220–233.
https://doi.org/10.1182/blood.2024025231
Published: 2025
Includes: Supplemental data
Journal Articles

Atalanta-1: A Phase 1/2 Trial of GLPG5101, a Fresh, Stem-like, Early Memory CD19 CAR T-Cell Therapy with a 7-Day Vein-to-Vein Time, for the Treatment of Relapsed/Refractory Non-Hodgkin Lymphoma

Marie José Kersten, Kirsten Saevels, Evelyne Willems, Marte C. Liefaard, Stavros Milatos, Margot J. Pont, Claire Vennin, Eva Santermans, Anna D. D. van Muyden, Jeevan Shetty, Esmée P. Hoefsmit, Omotayo Fasan, Maria T. Kuipers, Sébastien Anguille, Joost S.P. Vermaat
Journal: Blood
Blood (2024) 144 (Supplement 1): 93.
https://doi.org/10.1182/blood-2024-205360
Published: 2024
Journal Articles

Gamma Secretase Inhibition May Mitigate the Impact of Low BCMA Target Density in Relapsed/Refractory Multiple Myeloma: Results from a Comparative Analysis of Two Phase 1 Clinical Trials

Andrew J Portuguese, Sherilyn A. Tuazon, Margot J. Pont, Gabriel Cole, Blythe Duke Sather, Xiaoling Song, Brent L. Wood, Michelle Lee Blake, Melissa Works, Mazyar Shadman, Qian Vicky Wu, Jenna M. Voutsinas, Ted Gooley, Cameron J. Turtle, Brian G. Till, David G. Coffey, David G. Maloney, Edward Libby, Aude G Chapuis, Filippo Milano, Stanley R. Riddell, Andrew J. Cowan, Damian J. Green
Journal: Blood
Blood (2024) 144 (Supplement 1): 4832.
https://doi.org/10.1182/blood-2024-205942
Published: 2024
Journal Articles

Euplagia-1: A Phase 1/2 Trial of GLPG5201, a Fresh Stem-like Early Memory CD19 CAR T-Cell Therapy with a 7-Day Vein-to-Vein Time, in Patients with Relapsed/Refractory CLL and RT

Valentin Ortiz-Maldonado, Nuria Martínez-Cibrián, Leticia Alserawan, Sergi Betriu, Ana Triguero, Sandra Blum, Margaux Faes, Marte C. Liefaard, Margot J. Pont, Maike Spoon, Kirsten Van Hoorde, Anna D. D. van Muyden, Julio Delgado, Natalia Tovar
Journal: Blood
Blood (2024) 144 (Supplement 1): 3452.
https://doi.org/10.1182/blood-2024-207546
Published: 2024
Journal Articles

NOTCH1 signaling during CD4 + T-cell activation alters transcription factor networks and enhances antigen responsiveness

Alec B. Wilkens, Elena C. Fulton, Margot J. Pont, Gabriel O. Cole, Isabel Leung, Sylvia M. Stull, Matthew R. Hart, Irwin D. Bernstein, Scott N. Furlan, Stanley R. Riddell
Journal: Blood
Blood (2022) 140 (21): 2261–2275.
https://doi.org/10.1182/blood.2021015144
Published: 2022
Includes: Supplemental data
Journal Articles

γ-Secretase inhibition increases efficacy of BCMA-specific chimeric antigen receptor T cells in multiple myeloma

Margot J. Pont, Tyler Hill, Gabriel O. Cole, Joe J. Abbott, Jessica Kelliher, Alexander I. Salter, Michael Hudecek, Melissa L. Comstock, Anusha Rajan, Bharvin K. R. Patel, Jenna M. Voutsinas, Qian Wu, Lingfeng Liu, Andrew J. Cowan, Brent L. Wood, Damian J. Green, Stanley R. Riddell
Journal: Blood
Blood (2019) 134 (19): 1585–1597.
https://doi.org/10.1182/blood.2019000050
Published: 2019
Includes: Supplemental data
Journal Articles

Chimeric antigen receptor–modified T cells: CD19 and the road beyond

Clinical Trials & Observations
Alexander I. Salter, Margot J. Pont, Stanley R. Riddell
Journal: Blood
Blood (2018) 131 (24): 2621–2629.
https://doi.org/10.1182/blood-2018-01-785840
Published: 2018
Journal Articles

LB-ARHGDIB-1R As Novel Minor Histocompatibility Antigen For Therapeutic Application

Margot J Pont, Willemijn Hobo, PhD, M. Willy Honders, Simone A.P. van Luxemburg-Heijs, Michel G.D. Kester, Cornelis A.M. van Bergen, Harry Dolstra, PhD, J.H. Frederik Falkenburg, MD, PhD, Marieke Griffioen, PhD
Journal: Blood
Blood (2013) 122 (21): 4465.
https://doi.org/10.1182/blood.V122.21.4465.4465
Published: 2013