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María Jesús Blanchard
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Journal Articles

Analysis of Immunological and Clinical Response to Vaccination Against Sars-COV-2 in Patients with Chronic Myeloid Leukemia

Alejandro ZURDO Castronuño, Miriam Solera Sainero, Magdalena Corona, Monserrat Torres, Guiomar Casado-Fernandez, Fernando Ramos-García, Javier Garcia-Pérez, María Aranzazú Murciano-Antón, María Jesús Blanchard, Juan Marquet Palomanes, Fernando Martin Moro, Mayte Pérez-Olmeida, Javier López Jiménez, Maria Teresa Coiras, Sara Rodriguez-Mora, Valentín Garcia-Gutiérrez
Journal: Blood
Blood (2022) 140 (Supplement 1): 3923–3924.
DOI: https://doi.org/10.1182/blood-2022-169512
Published: 2022
Journal Articles

Belantamab Mafodotin in Patients with Relapsed/Refractory Multiple Myeloma Included in the Compassionate Use or the Expanded Access Program. Experience with a Spanish Cohort

Javier De La Rubia, Rafael Alonso, Maria Esther Clavero Sanchez, Elham Askari, Alfonso García de Coca, Ana Maldonado, Margarita Fernandez De La Mata, Fernando Escalante, Ana Garcia-Feria, Rafael Rios, Venancio Conesa, Maria Aranzazu Bermudez, Beatriz Merchan, Alberto Velasco, María Jesús Blanchard, Antonia Sampol, Eukene Gainza González, Pedro M Hernandez, Veronica Gonzalez-Calle, Adrian Alegre
Journal: Blood
Blood (2022) 140 (Supplement 1): 4315–4317.
DOI: https://doi.org/10.1182/blood-2022-158538
Published: 2022
Journal Articles

Clinical Impact of Next Generation Flow in Bone Marrow Vs Qip-Mass Spectrometry in Peripheral Blood to Assess Minimal Residual Disease in Newly Diagnosed Multiple Myeloma Patients Receiving Maintenance As Part of the GEM2014MAIN Trial

Noemi Puig, Cristina Agulló, Teresa Contreras Sanfeliciano, Bruno Paiva, María Teresa Cedena, Laura Rosinol Dachs, Ramón García-Sanz, Joaquín Martínez-López, Albert Oriol, María Jesús Blanchard, Rafael Rios, Jesus Martin, Anna Sureda, Miguel Hernández, Javier de la Rubia, Jose Maria Moraleda, Felipe De Arriba, Luis Palomera, Belén Iñigo, Joan Bargay, Joan Bladé Creixenti, Jesús San-Miguel, Juan Jose Lahuerta, María-Victoria Mateos
Journal: Blood
Blood (2022) 140 (Supplement 1): 2098–2100.
DOI: https://doi.org/10.1182/blood-2022-165441
Published: 2022
Journal Articles

Recovery of Uninvolved Heavy/Light Chain Pair Immunoparesis during Maintenance Is an Independent Prognostic Factor for Multiple Myeloma and Could Complement Prognosis Value of Minimal Residual Disease

Sunil Lakhwani, Laura Rosinol Dachs, Noemi Puig, Miguel Angel Pico Picos, Laura Medina-González, Joaquín Martínez-López, Bruno Paiva, Albert Oriol, Rafael Rios, María Jesús Blanchard, Isidro Jarque, Joan Bargay, Jose Maria Moraleda, Estrella Carrillo-Cruz, Anna Sureda, Isabel Krsnik, Esther González Garcia, Luis Felipe Casado Montero, Josep M Marti, Cristina Encinas, Felipe De Arriba, Luis Palomera, Antonia Sampol, Yolanda Gonzalez-Montes, Cristina Motllo, Javier De La Cruz, Rafael Alonso Fernández, María-Victoria Mateos, Joan Bladé Creixenti, Juan-José Lahuerta, Jesús San-Miguel, Miguel-Teodoro Hernández
Journal: Blood
Blood (2022) 140 (Supplement 1): 2101–2103.
DOI: https://doi.org/10.1182/blood-2022-167247
Published: 2022
Journal Articles

Validation of the International Myeloma Working Group standard response criteria in the PETHEMA/GEM2012MENOS65 study: are these times of change?

Clinical Trials & Observations
Ana Jiménez-Ubieto, Bruno Paiva, Noemi Puig, Maria-Teresa Cedena, Joaquín Martínez-López, Albert Oriol, María-Jesús Blanchard, Rafael Ríos, Jesús Martin, Rafael Martínez, Anna Sureda, Miguel-Teodoro Hernández, Javier de la Rubia, Isabel Krnisk, Valentín Cabañas, Luis Palomera, José María Sánchez-Pina, Joan Bargay, María-Victoria Mateos, Laura Rosiñol, Joan Blade, Jesús San Miguel, Juan José Lahuerta, on behalf of the GEM (Grupo Español de Mieloma)/PETHEMA (Programa Español de Tratamientos en Hematología) Cooperative Study Group
Journal: Blood
Blood (2021) 138 (19): 1901–1905.
DOI: https://doi.org/10.1182/blood.2021012319
Published: 2021
Includes: Supplemental data
Journal Articles

Ixazomib Plus Lenalidomide/Dexamethasone (IRd) Versus Lenalidomide /Dexamethasone (Rd) Maintenance after Autologous Stem Cell Transplant in Patients with Newly Diagnosed Multiple Myeloma: Results of the Spanish GEM2014MAIN Trial

Laura Rosinol, Albert Oriol, Rafael Ríos Tamayo, María Jesús Blanchard, Isidro Jarque, Joan Bargay, Miguel-Teodoro Hernández, Jose Maria Moraleda, Estrella Carrillo-Cruz, Anna Sureda, Joaquín Martínez-López, Isabel Krsnik, Esther González Garcia, Felipe Casado, Josep M Marti, Cristina Encinas, Felipe De Arriba, Luis Palomera, Antonia Sampol, Yolanda Gonzalez-Montes, Elena Cabezudo, Maria-Victoria Mateos, Jesus San-Miguel, Juan Jose Lahuerta, Joan Bladé Creixenti
Journal: Blood
Blood (2021) 138 (Supplement 1): 466.
DOI: https://doi.org/10.1182/blood-2021-146798
Published: 2021
Journal Articles

Assessment of Treatment Response By Ife, Next Generation Flow Cytometry and Mass Spectrometry Coupled with Liquid Chromatography in the GEM2012MENOS65 Clinical Trial

Noemi Puig, Teresa Contreras Sanfeliciano, Bruno Paiva, María Teresa Cedena, Laura Rosinol, Ramón Garcia-Sanz, Joaquín Martínez-López, Albert Oriol, María Jesús Blanchard, Rafael Rios, Jesus Martin, Anna Sureda, Miguel Hernández, Javier De La Rubia, Isabel Krsnik, Jose Maria Moraleda, Belén Iñigo, Luis Palomera, Cristina Agulló, Joan Bargay, Joan Bladé Creixenti, Jesús San-Miguel, Juan-José Lahuerta, Maria-Victoria Mateos
Journal: Blood
Blood (2021) 138 (Supplement 1): 544.
DOI: https://doi.org/10.1182/blood-2021-151557
Published: 2021
Journal Articles

Compassionate Use of Belantamab Mafodotin for Treatment of Patients with Relapsed/Refractory Multiple Myeloma Heavily Treated. Spanish Experience

Adrian Alegre, Gonzalo Benzo Callejo, Rafael Alonso Fernández, Joaquin Martínez-López, Ana Jimenez-Ubieto, Clara Cuellar, Elham Askari, Elena Prieto, Concha Alaez, Beatriz Aguado, Alberto Velasco, Isabel Krsnik, Laura Llorente, Cristina Muñoz-Linares, Ana Morales, Eugenio Gimenez Mesa, Rebeca Iglesias, Carmen Martínez-Chamorro, Arancha Alonso, Carmen Jiménez-Montes, María Jesús Blanchard
Journal: Blood
Blood (2021) 138 (Supplement 1): 3775.
DOI: https://doi.org/10.1182/blood-2021-151267
Published: 2021
Journal Articles

Severity of Covid-19 Clinical Outcomes and Mortality in Multiple Myeloma Patients over Year 1 of the Pandemic

Joaquín Martínez-López, Maria-Victoria Mateos, Nieves López-Muñoz, Maria Alicia Senin Magan, Maria Dunia De Miguel, Ana López de la Guía, Anna Sureda, Cristina Encinas, Diego Conde Royo, Laura Rosinol, Lucía García Tomás, Jose Angel Hernandez-Rivas, Javier Alberto Rojas, Adrian Alegre, María Jesús Blanchard, Fernando Escalante Barrigón, Esther González Garcia, Belén Iñigo, Pilar Bravo Barahona, F. Javier Penalver, Javier De La Rubia, Noemi Fernandez-Escalada, Jose Maria Alonso Alonso, Joan Bladé, Juan Jose Lahuerta, Javier De La Cruz, Jesús F. San-Miguel
Journal: Blood
Blood (2021) 138 (Supplement 1): 2719.
DOI: https://doi.org/10.1182/blood-2021-149192
Published: 2021
Journal Articles

Characterization of the Early Humoral and Cellular Response Developed in Oncohematological Patients Post-Vaccination with One Dose Against COVID-19

Magdalena Corona De Lapuerta, Sara Rodriguez-Mora, Guiomar Casado-Fernandez, Javier Garcia-Pérez, Lorena Vigon, María Aranzazú Murciano-Antón, María Jesús Blanchard, Juan Marquet Palomanes, Fernando Martin Moro, Pablo Palomo Rumschisky, Mayte Pérez-Olmeida, Javier López Jiménez, Maria Rosa López-Huertas, Maria Teresa Coiras, Valentín Garcia Gutierrez
Journal: Blood
Blood (2021) 138 (Supplement 1): 195.
DOI: https://doi.org/10.1182/blood-2021-152943
Published: 2021
Journal Articles

Randomized Phase 2 Study of Weekly Carfilzomib 70 Mg/m2 and Dexamethasone Plus/Minus Cyclophosphamide in Relapsed and/or Refractory Multiple Myeloma (RRMM) Patients (GEM-KyCyDex)

Maria-Victoria Mateos, MD PhD, Enrique M. Ocio, MDPhD, Anna Sureda Balari, MD PhD, Albert Oriol, Esther González Garcia, MD, Maria José Moreno, Miquel Granell, MD, Fernando Escalante, MD, Veronica Gonzalez De La Calle, MD PhD, Laura Rosinol Dachs, Estrella Carrillo-Cruz, MD, Joaquín Martínez-López, Maria Victoria Dourdil Sahun, Marta Sonia Gonzalez, MD, Jaime Perez De Oteyza, MDPhD, Felipe De Arriba, PhD, Miguel T Hernández, MD PhD, Aránzazu García Mateo, PhD, Ana Pilar Gonzalez, PhD, Rafael Rios, MD PhD, Carmen Cabrera, Juan Jose Bargay, Paula Rodriguez-Otero, MD, Felipe Casado, Maria Casanova, MD, María Jesús Blanchard, Joan Blade Creixenti, Juan Jose Lahuerta, MD PhD, Jesus F. San-Miguel, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 8–9.
DOI: https://doi.org/10.1182/blood-2020-140934
Published: 2020
Journal Articles

Clinical Significance and Biomarkers to Predict Unsustained Complete Remission in Transplant-Eligible Multiple Myeloma

Ana Jimenez-Ubieto, Bruno Paiva, PhD, Joaquin Martinez Lopez, María Teresa Cedena, MD, Noemi Puig, MD PhD, Albert Oriol, MD, Maria Jesús Blanchard, MD, Rafael Rios, MD PhD, Lucia Lopez-Anglada, PhD, Jesús Martín, Rafael Martínez, Anna Sureda Balari, MD PhD, Miguel Hernández, Javier de la Rubia, Isabel Krsnik, MD PhD, Valentin Cabañas, MD, Luis Palomera, MD PhD, Joan Bargay, MD, Jose Maria Moraleda, MD PhD, Laura Rosiñol, María-Victoria Mateos, MD PhD, Jesus F. San-Miguel, MD PhD, Joan Bladé, MD PhD, Juan-José Lahuerta, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 5–6.
DOI: https://doi.org/10.1182/blood-2020-136181
Published: 2020
Journal Articles

Clinical Validation of a NGS Capture Panel to Identify Mutations, Copy Number Variations and Translocations in Patients with Multiple Myeloma

Isabel Cuenca, MSc, Alejandro Medina, MD, Laura Rosinol, MD PhD, Iria Vazquez, PhD BSc, Ricardo Sanchez, Norma C. Gutierrez, MD PhD, Yanira Ruiz-Heredia, Santiago Barrio, Albert Oriol, MD, Maria Luisa Martin-Ramos, Manuela Fernández-Guijarro, María Jesús Blanchard, Rafael Rios, MD PhD, Anna Sureda Balari, MD PhD, Miguel T Hernández, Javier de la Rubia, Gorka Alkorta, Xabier Agirre, PhD, Gonzalo R Ordóñez, Rafael Valdés-Mas, Maria-Victoria Mateos, MD PhD, Joan Blade Creixenti, Juan Jose Lahuerta, MD PhD, Jesus F. San-Miguel, MD PhD, Maria Jose Calasanz, PhD BSc, Ramon Garcia-Sanz, Joaquin Martinez-Lopez, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 13–14.
DOI: https://doi.org/10.1182/blood-2020-140711
Published: 2020
Journal Articles

Immunogenomic identification and characterization of granulocytic myeloid-derived suppressor cells in multiple myeloma

Cristina Perez, Cirino Botta, Aintzane Zabaleta, Noemi Puig, Maria-Teresa Cedena, Ibai Goicoechea, Daniel Alameda, Edurne San José-Eneriz, Juana Merino, Paula Rodríguez-Otero, Catarina Maia, Diego Alignani, Patricia Maiso, Irene Manrique, David Lara-Astiaso, Amaia Vilas-Zornoza, Sarai Sarvide, Caterina Riillo, Marco Rossi, Laura Rosiñol, Albert Oriol, María-Jesús Blanchard, Rafael Rios, Anna Sureda, Jesus Martin, Rafael Martinez, Joan Bargay, Javier de la Rubia, Miguel-Teodoro Hernandez, Joaquin Martinez-Lopez, Alberto Orfao, Xabier Agirre, Felipe Prosper, Maria-Victoria Mateos, Juan-José Lahuerta, Joan Blade, Jesús F. San-Miguel, Bruno Paiva
Journal: Blood
Blood (2020) 136 (2): 199–209.
DOI: https://doi.org/10.1182/blood.2019004537
Published: 2020
Includes: Supplemental data
Journal Articles

Single-Cell Characterization of the Multiple Myeloma (MM) Immune Microenvironment Identifies CD27-Negative T Cells As Potential Source of Tumor-Reactive Lymphocytes

Cirino Botta, MD, Cristina Pérez Ruiz, Ibai Goicoechea, PhD, Noemi Puig, MD PhD, María Teresa Cedena, Lourdes Cordon, Aintzane Zabaleta, PhD, Leire Burgos, Catarina Maia, Sara Rodríguez, PhD, Idoia Rodriguez, Sarai Sarvide, Diego Alignani, PhD, Amaia Vilas-Zornoza, PhD, Erika Lorenzo-Vivas, PhD, Laura Rosinol Dachs, Albert Oriol, MD, María Jesús Blanchard, Rafael Rios, MD PhD, Anna Sureda, MD PhD, Rafael Martínez, Jesús Martín, Joan Bargay, MD PhD, Javier De La Rubia, Marco Rossi, MD, Pierosandro Tagliaferri, MD, Pierfrancesco Tassone, MD, Massimo Gentile, Juana Merino, Felipe Prosper, MD PhD, Alberto Orfao, MD PhD, Maria-Victoria Mateos, Juan-José Lahuerta, MD PhD, Joan Bladé, MD PhD, Jesús San-Miguel, Bruno Paiva, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 506.
DOI: https://doi.org/10.1182/blood-2019-123974
Published: 2019
Journal Articles

Validation of Daraex to Resolve Daratumumab-Induced Interferences in Pre-Transfusion Screen Tests

Maria Tenorio, PhD, Gemma Moreno Jiménez, MD, Valentín García Gutiérrez, PhD, Ana Jiménez, Maria Jesús Blanchard, MD, Ana Vallés, Sandra López, Pilar Herrera, MD, Javier Lopez Jimenez, MD PhD, Anabelle Chinea, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4983.
DOI: https://doi.org/10.1182/blood-2019-131345
Published: 2019
Journal Articles

Bortezomib, lenalidomide, and dexamethasone as induction therapy prior to autologous transplant in multiple myeloma

Laura Rosiñol, Albert Oriol, Rafael Rios, Anna Sureda, María Jesús Blanchard, Miguel Teodoro Hernández, Rafael Martínez-Martínez, Jose M. Moraleda, Isidro Jarque, Juan Bargay, Mercedes Gironella, Felipe de Arriba, Luis Palomera, Yolanda González-Montes, Josep M. Martí, Isabel Krsnik, Jose M. Arguiñano, Maria Esther González, Ana Pilar González, Luis Felipe Casado, Lucia López-Anglada, Bruno Paiva, Maria-Victoria Mateos, Jesus F. San Miguel, Juan-José Lahuerta, Joan Bladé
Journal: Blood
Blood (2019) 134 (16): 1337–1345.
DOI: https://doi.org/10.1182/blood.2019000241
Published: 2019
Includes: Supplemental data
Journal Articles

Role of urine immunofixation in the complete response assessment of MM patients other than light-chain-only disease

CME Clinical Trials & Observations Brief Report
Juan-José Lahuerta, Ana Jiménez-Ubieto, Bruno Paiva, Joaquín Martínez-López, José González-Medina, Lucía López-Anglada, María-Teresa Cedena, Noemi Puig, Albert Oriol, María-Jesús Blanchard, Rafael Ríos, Jesús Martin, Rafael Martínez, Anna Sureda, Miguel Teodoro Hernández, Javier de la Rubia, Isabel Krsnik, Valentín Cabañas, Luis Palomera, Joan Bargay, María-Victoria Mateos, Laura Rosiñol, Jesús F. San Miguel, Joan Blade
Journal: Blood
Blood (2019) 133 (25): 2664–2668.
DOI: https://doi.org/10.1182/blood.2019000671
Published: 2019
Journal Articles

Integrated Analysis of Randomized Controlled Trials Evaluating Bortezomib + Lenalidomide + Dexamethasone or Bortezomib + Thalidomide + Dexamethasone Induction in Transplant-Eligible Newly Diagnosed Multiple Myeloma

Laura Rosinol Dachs, Benjamin Hebraud, Albert Oriol, MD, Anne-Laurène Colin, Rafael Rios, MD PhD, Cyrille Hulin, Maria Jesús Blanchard, MD, Denis Caillot, Anna Sureda, MD, Miguel T Hernández, MD PhD, Bertrand Arnulf, Maria-Victoria Mateos, MD PhD, Margaret Macro, Jesús F San-Miguel, MD, Karim Belhadj, Juan Jose Lahuerta, MD PhD, Guang Chen, M. Brigid Garelik, Joan Bladé, MD, Philippe Moreau, Michel Attal, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3245.
DOI: https://doi.org/10.1182/blood-2018-99-112659
Published: 2018
Journal Articles

Safety and efficacy of pomalidomide plus low-dose dexamethasone in STRATUS (MM-010): a phase 3b study in refractory multiple myeloma

Clinical Trials & Observations
Meletios A. Dimopoulos, Antonio Palumbo, Paolo Corradini, Michele Cavo, Michel Delforge, Francesco Di Raimondo, Katja C. Weisel, Albert Oriol, Markus Hansson, Angelo Vacca, María Jesús Blanchard, Hartmut Goldschmidt, Chantal Doyen, Martin Kaiser, Mario Petrini, Pekka Anttila, Anna Maria Cafro, Reinier Raymakers, Jesus San-Miguel, Felipe de Arriba, Stefan Knop, Christoph Röllig, Enrique M. Ocio, Gareth Morgan, Neil Miller, Mathew Simcock, Teresa Peluso, Jennifer Herring, Lars Sternas, Mohamed H. Zaki, Philippe Moreau
Journal: Blood
Blood (2016) 128 (4): 497–503.
DOI: https://doi.org/10.1182/blood-2016-02-700872
Published: 2016