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Journal Articles

A mechanism for hereditary angioedema caused by a methionine-379–to–lysine substitution in kininogens

S. Kent Dickeson, Sunil Kumar, Mao-fu Sun, Maxim Litvak, Tracey Z. He, Dennis R. Phillips, Elijah T. Roberts, Edward P. Feener, Ruby H. P. Law, David Gailani
Journal: Blood
Blood (2024) 143 (7): 641–650.
https://doi.org/10.1182/blood.2023022254
Published: 2024
Includes: Supplemental data
Journal Articles

First Validated Model of Zymogen Factor XII Provides Insights into Protein Assembly and Activation

Aleksandr Shamanaev, Mao-Fu Sun, Michal Ponczek, Jonas Emsley, David Gailani
Journal: Blood
Blood (2023) 142 (Supplement 1): 23.
https://doi.org/10.1182/blood-2023-190006
Published: 2023
Journal Articles

A mechanism for hereditary angioedema caused by a lysine 311–to–glutamic acid substitution in plasminogen

S. Kent Dickeson, Sunil Kumar, Mao-Fu Sun, Bassem M. Mohammed, Dennis R. Phillips, James C. Whisstock, Adam J. Quek, Edward P. Feener, Ruby H. P. Law, David Gailani
Journal: Blood
Blood (2022) 139 (18): 2816–2829.
https://doi.org/10.1182/blood.2021012945
Published: 2022
Includes: Supplemental data
Journal Articles

Protease activity in single-chain prekallikrein

Ivan Ivanov, Ingrid M. Verhamme, Mao-fu Sun, Bassem Mohammed, Qiufang Cheng, Anton Matafonov, S. Kent Dickeson, Kusumam Joseph, Allen P. Kaplan, David Gailani
Journal: Blood
Blood (2020) 135 (8): 558–567.
https://doi.org/10.1182/blood.2019002224
Published: 2020
Includes: Supplemental data
Journal Articles

A mechanism for hereditary angioedema with normal C1 inhibitor: an inhibitory regulatory role for the factor XII heavy chain

Ivan Ivanov, Anton Matafonov, Mao-fu Sun, Bassem M. Mohammed, Qiufang Cheng, S. Kent Dickeson, Suman Kundu, Ingrid M. Verhamme, Andras Gruber, Keith McCrae, David Gailani
Journal: Blood
Blood (2019) 133 (10): 1152–1163.
https://doi.org/10.1182/blood-2018-06-860270
Published: 2019
Includes: Supplemental data
Journal Articles

Proteolytic properties of single-chain factor XII: a mechanism for triggering contact activation

Ivan Ivanov, Anton Matafonov, Mao-fu Sun, Qiufang Cheng, S. Kent Dickeson, Ingrid M. Verhamme, Jonas Emsley, David Gailani
Journal: Blood
Blood (2017) 129 (11): 1527–1537.
https://doi.org/10.1182/blood-2016-10-744110
Published: 2017
Includes: Supplemental data
Journal Articles

Coagulation Factor XI and Factor XII in DNA-Induced Thrombin Generation

Anton Matafonov, MD, Ivan S. Ivanov, PhD, Mao-fu Sun, David Gailani, MD
Journal: Blood
Blood (2014) 124 (21): 581.
https://doi.org/10.1182/blood.V124.21.581.581
Published: 2014
Journal Articles

Factor XII inhibition reduces thrombus formation in a primate thrombosis model

Anton Matafonov, Philberta Y. Leung, Adam E. Gailani, Stephanie L. Grach, Cristina Puy, Qiufang Cheng, Mao-fu Sun, Owen J. T. McCarty, Erik I. Tucker, Hiroaki Kataoka, Thomas Renné, James H. Morrissey, Andras Gruber, David Gailani
Journal: Blood
Blood (2014) 123 (11): 1739–1746.
https://doi.org/10.1182/blood-2013-04-499111
Published: 2014
Includes: Supplemental data
Journal Articles

The dimeric structure of factor XI and zymogen activation

Yipeng Geng, Ingrid M. Verhamme, Stephen B. Smith, Mao-fu Sun, Anton Matafonov, Qiufang Cheng, Stephanie A. Smith, James H. Morrissey, David Gailani
Journal: Blood
Blood (2013) 121 (19): 3962–3969.
https://doi.org/10.1182/blood-2012-12-473629
Published: 2013
Journal Articles

The Interaction of Coagulation Factor XI with Polyphosphate

Yipeng Geng, Ingrid M. Verhamme, PhD, Qiufang Cheng, MD, Anton Matafonov, MD, Stephen B. Smith, PhD, Mao-fu Sun, Stephanie A. Smith, DVM, MS, James H. Morrissey, PhD, David Gailani, MD
Journal: Blood
Blood (2012) 120 (21): 498.
https://doi.org/10.1182/blood.V120.21.498.498
Published: 2012
Journal Articles

Exosite Interactions in Factor IX Activation by Factor XIa

Yipeng Geng, Ingrid M. Verhamme, PhD, Stephen B. Smith, PhD, Amanda S. Messer, Mao-fu Sun, S. Paul Bajaj, David Gailani, MD
Journal: Blood
Blood (2011) 118 (21): 2235.
https://doi.org/10.1182/blood.V118.21.2235.2235
Published: 2011
Journal Articles

Evidence for a Factor IX-Independent Role for Factor XI in Thrombin Generation

Anton Matafonov, MD, Qiufang Cheng, MD, Ingrid M. Verhamme, PhD, Obi Umunakwe, Erik I. Tucker, PhD, Mao-fu Sun, Andras Gruber, MD, David Gailani, MD
Journal: Blood
Blood (2011) 118 (21): 2244.
https://doi.org/10.1182/blood.V118.21.2244.2244
Published: 2011
Journal Articles

Activation of factor XI by products of prothrombin activation

Anton Matafonov, Suryakala Sarilla, Mao-fu Sun, John P. Sheehan, Vladimir Serebrov, Ingrid M. Verhamme, David Gailani
Journal: Blood
Blood (2011) 118 (2): 437–445.
https://doi.org/10.1182/blood-2010-10-312983
Published: 2011
Journal Articles

Activation of Factor XI and the Contact Proteases by Products of Prothrombin Activation.

Anton Matafonov, MD, Suryakala Sarilla, PhD, Mao-fu Sun, John P. Sheehan, MD, Vladimir Serebrov, MD, PhD, DMSci, Ingrid Verhamme, PhD, David Gailani, MD
Journal: Blood
Blood (2010) 116 (21): 1150.
https://doi.org/10.1182/blood.V116.21.1150.1150
Published: 2010
Journal Articles

A role for factor XIIa–mediated factor XI activation in thrombus formation in vivo

Qiufang Cheng, Erik I. Tucker, Meghann S. Pine, India Sisler, Anton Matafonov, Mao-fu Sun, Tara C. White-Adams, Stephanie A. Smith, Stephen R. Hanson, Owen J. T. McCarty, Thomas Renné, András Gruber, David Gailani
Journal: Blood
Blood (2010) 116 (19): 3981–3989.
https://doi.org/10.1182/blood-2010-02-270918
Published: 2010
Includes: Supplemental data
Journal Articles

Evidence against a protein in plasma that is a product of a factor XI mRNA splice variant missing exons 6 and 7

David Gailani, Mao-fu Sun, Qiufang Cheng, Anton Matafonov, Erik I. Tucker, Andras Gruber, Jonas Emsley
Journal: Blood
Blood (2010) 116 (7): 1185–1186.
https://doi.org/10.1182/blood-2010-01-265702
Published: 2010
Journal Articles

Factor XI contributes to thrombin generation in the absence of factor XII

Dmitri V. Kravtsov, Anton Matafonov, Erik I. Tucker, Mao-fu Sun, Peter N. Walsh, Andras Gruber, David Gailani
Journal: Blood
Blood (2009) 114 (2): 452–458.
https://doi.org/10.1182/blood-2009-02-203604
Published: 2009
Journal Articles

Characterization of Heparin Binding Site Residues on the Catalytic Domain of Factor XIa

Likui Yang, Ph.D., Mao-fu Sun, Chandrashekhara Manithody, Ph.D., David Gailani, MD, Alireza R. Rezaie, PhD
Journal: Blood
Blood (2008) 112 (11): 1018.
https://doi.org/10.1182/blood.V112.11.1018.1018
Published: 2008
Journal Articles

Factor XI Contributes to Thrombin Generation in the Absence of Factor XIIa

Anton Matafonov, Dmitri Kravtsov, Erik I. Tucker, Mao-fu Sun, John P. Sheehan, MD, Andras Gruber, MD, David Gailani
Journal: Blood
Blood (2008) 112 (11): 3082.
https://doi.org/10.1182/blood.V112.11.3082.3082
Published: 2008
Journal Articles

Structural and Functional Significance of Amino Acid Lysine192 (chymotrypsin numbering) in Factor XIa and Factor VIIa.

Amy E Schmidt, Sayeh Agah, Mao-fu Sun, Kaillathe Padmanabhan, Duilio Cascio, David Gailani, S. Paul Bajaj
Journal: Blood
Blood (2008) 112 (11): 2030.
https://doi.org/10.1182/blood.V112.11.2030.2030
Published: 2008