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Journal Articles

A mechanism for hereditary angioedema caused by a lysine 311–to–glutamic acid substitution in plasminogen

S. Kent Dickeson, Sunil Kumar, Mao-Fu Sun, Bassem M. Mohammed, Dennis R. Phillips, James C. Whisstock, Adam J. Quek, Edward P. Feener, Ruby H. P. Law, David Gailani

Blood (2022) 139 (18): 2816–2829.

DOI: https://doi.org/10.1182/blood.2021012945

Published: 2022

Includes: Supplemental data

Journal Articles

Protease activity in single-chain prekallikrein

Ivan Ivanov, Ingrid M. Verhamme, Mao-fu Sun, Bassem Mohammed, Qiufang Cheng, Anton Matafonov, S. Kent Dickeson, Kusumam Joseph, Allen P. Kaplan, David Gailani

Blood (2020) 135 (8): 558–567.

DOI: https://doi.org/10.1182/blood.2019002224

Published: 2020

Includes: Supplemental data

Journal Articles

A mechanism for hereditary angioedema with normal C1 inhibitor: an inhibitory regulatory role for the factor XII heavy chain

Ivan Ivanov, Anton Matafonov, Mao-fu Sun, Bassem M. Mohammed, Qiufang Cheng, S. Kent Dickeson, Suman Kundu, Ingrid M. Verhamme, Andras Gruber, Keith McCrae, David Gailani

Blood (2019) 133 (10): 1152–1163.

DOI: https://doi.org/10.1182/blood-2018-06-860270

Published: 2019

Includes: Supplemental data

Journal Articles

Proteolytic properties of single-chain factor XII: a mechanism for triggering contact activation

Ivan Ivanov, Anton Matafonov, Mao-fu Sun, Qiufang Cheng, S. Kent Dickeson, Ingrid M. Verhamme, Jonas Emsley, David Gailani

Blood (2017) 129 (11): 1527–1537.

DOI: https://doi.org/10.1182/blood-2016-10-744110

Published: 2017

Includes: Supplemental data

Journal Articles

Coagulation Factor XI and Factor XII in DNA-Induced Thrombin Generation

Anton Matafonov, MD, Ivan S. Ivanov, PhD, Mao-fu Sun, David Gailani, MD

Blood (2014) 124 (21): 581.

DOI: https://doi.org/10.1182/blood.V124.21.581.581

Published: 2014

Journal Articles

Factor XII inhibition reduces thrombus formation in a primate thrombosis model

Anton Matafonov, Philberta Y. Leung, Adam E. Gailani, Stephanie L. Grach, Cristina Puy, Qiufang Cheng, Mao-fu Sun, Owen J. T. McCarty, Erik I. Tucker, Hiroaki Kataoka, Thomas Renné, James H. Morrissey, Andras Gruber, David Gailani

Blood (2014) 123 (11): 1739–1746.

DOI: https://doi.org/10.1182/blood-2013-04-499111

Published: 2014

Includes: Supplemental data

Journal Articles

The dimeric structure of factor XI and zymogen activation

Yipeng Geng, Ingrid M. Verhamme, Stephen B. Smith, Mao-fu Sun, Anton Matafonov, Qiufang Cheng, Stephanie A. Smith, James H. Morrissey, David Gailani

Blood (2013) 121 (19): 3962–3969.

DOI: https://doi.org/10.1182/blood-2012-12-473629

Published: 2013

Journal Articles

The Interaction of Coagulation Factor XI with Polyphosphate

Yipeng Geng, Ingrid M. Verhamme, PhD, Qiufang Cheng, MD, Anton Matafonov, MD, Stephen B. Smith, PhD, Mao-fu Sun, Stephanie A. Smith, DVM, MS, James H. Morrissey, PhD, David Gailani, MD

Blood (2012) 120 (21): 498.

DOI: https://doi.org/10.1182/blood.V120.21.498.498

Published: 2012

Journal Articles

Exosite Interactions in Factor IX Activation by Factor XIa

Yipeng Geng, Ingrid M. Verhamme, PhD, Stephen B. Smith, PhD, Amanda S. Messer, Mao-fu Sun, S. Paul Bajaj, David Gailani, MD

Blood (2011) 118 (21): 2235.

DOI: https://doi.org/10.1182/blood.V118.21.2235.2235

Published: 2011

Journal Articles

Evidence for a Factor IX-Independent Role for Factor XI in Thrombin Generation

Anton Matafonov, MD, Qiufang Cheng, MD, Ingrid M. Verhamme, PhD, Obi Umunakwe, Erik I. Tucker, PhD, Mao-fu Sun, Andras Gruber, MD, David Gailani, MD

Blood (2011) 118 (21): 2244.

DOI: https://doi.org/10.1182/blood.V118.21.2244.2244

Published: 2011

Journal Articles

Activation of factor XI by products of prothrombin activation

Anton Matafonov, Suryakala Sarilla, Mao-fu Sun, John P. Sheehan, Vladimir Serebrov, Ingrid M. Verhamme, David Gailani

Blood (2011) 118 (2): 437–445.

DOI: https://doi.org/10.1182/blood-2010-10-312983

Published: 2011

Journal Articles

Activation of Factor XI and the Contact Proteases by Products of Prothrombin Activation.

Anton Matafonov, MD, Suryakala Sarilla, PhD, Mao-fu Sun, John P. Sheehan, MD, Vladimir Serebrov, MD, PhD, DMSci, Ingrid Verhamme, PhD, David Gailani, MD

Blood (2010) 116 (21): 1150.

DOI: https://doi.org/10.1182/blood.V116.21.1150.1150

Published: 2010

Journal Articles

A role for factor XIIa–mediated factor XI activation in thrombus formation in vivo

Qiufang Cheng, Erik I. Tucker, Meghann S. Pine, India Sisler, Anton Matafonov, Mao-fu Sun, Tara C. White-Adams, Stephanie A. Smith, Stephen R. Hanson, Owen J. T. McCarty, Thomas Renné, András Gruber, David Gailani

Blood (2010) 116 (19): 3981–3989.

DOI: https://doi.org/10.1182/blood-2010-02-270918

Published: 2010

Includes: Supplemental data

Journal Articles

Evidence against a protein in plasma that is a product of a factor XI mRNA splice variant missing exons 6 and 7

David Gailani, Mao-fu Sun, Qiufang Cheng, Anton Matafonov, Erik I. Tucker, Andras Gruber, Jonas Emsley

Blood (2010) 116 (7): 1185–1186.

DOI: https://doi.org/10.1182/blood-2010-01-265702

Published: 2010

Journal Articles

Factor XI contributes to thrombin generation in the absence of factor XII

Dmitri V. Kravtsov, Anton Matafonov, Erik I. Tucker, Mao-fu Sun, Peter N. Walsh, Andras Gruber, David Gailani

Blood (2009) 114 (2): 452–458.

DOI: https://doi.org/10.1182/blood-2009-02-203604

Published: 2009

Journal Articles

Characterization of Heparin Binding Site Residues on the Catalytic Domain of Factor XIa

Likui Yang, Ph.D., Mao-fu Sun, Chandrashekhara Manithody, Ph.D., David Gailani, MD, Alireza R. Rezaie, PhD

Blood (2008) 112 (11): 1018.

DOI: https://doi.org/10.1182/blood.V112.11.1018.1018

Published: 2008

Journal Articles

Structural and Functional Significance of Amino Acid Lysine192 (chymotrypsin numbering) in Factor XIa and Factor VIIa.

Amy E Schmidt, Sayeh Agah, Mao-fu Sun, Kaillathe Padmanabhan, Duilio Cascio, David Gailani, S. Paul Bajaj

Blood (2008) 112 (11): 2030.

DOI: https://doi.org/10.1182/blood.V112.11.2030.2030

Published: 2008

Journal Articles

Factor XI Contributes to Thrombin Generation in the Absence of Factor XIIa

Anton Matafonov, Dmitri Kravtsov, Erik I. Tucker, Mao-fu Sun, John P. Sheehan, MD, Andras Gruber, MD, David Gailani

Blood (2008) 112 (11): 3082.

DOI: https://doi.org/10.1182/blood.V112.11.3082.3082

Published: 2008

Journal Articles

Independence of Factor XIa Subunits in Factor IX Activation.

Stephen B. Smith, BS, Mao-fu Sun, BS, Paul E. Bock, PhD, David Gailani, MD

Blood (2006) 108 (11): 334.

DOI: https://doi.org/10.1182/blood.V108.11.334.334

Published: 2006

Journal Articles

Dominant factor XI deficiency caused by mutations in the factor XI catalytic domain

Dmitri V. Kravtsov, Wenman Wu, Joost C. M. Meijers, Mao-Fu Sun, Morey A. Blinder, Thao P. Dang, Hongli Wang, David Gailani

Blood (2004) 104 (1): 128–134.

DOI: https://doi.org/10.1182/blood-2003-10-3530

Published: 2004

NARROW

A mechanism for hereditary angioedema caused by a lysine 311–to–glutamic acid substitution in plasminogen

Protease activity in single-chain prekallikrein

A mechanism for hereditary angioedema with normal C1 inhibitor: an inhibitory regulatory role for the factor XII heavy chain

Proteolytic properties of single-chain factor XII: a mechanism for triggering contact activation

Coagulation Factor XI and Factor XII in DNA-Induced Thrombin Generation

Factor XII inhibition reduces thrombus formation in a primate thrombosis model

The dimeric structure of factor XI and zymogen activation

The Interaction of Coagulation Factor XI with Polyphosphate

Exosite Interactions in Factor IX Activation by Factor XIa

Evidence for a Factor IX-Independent Role for Factor XI in Thrombin Generation

Activation of factor XI by products of prothrombin activation

Activation of Factor XI and the Contact Proteases by Products of Prothrombin Activation.

A role for factor XIIa–mediated factor XI activation in thrombus formation in vivo

Evidence against a protein in plasma that is a product of a factor XI mRNA splice variant missing exons 6 and 7

Factor XI contributes to thrombin generation in the absence of factor XII

Characterization of Heparin Binding Site Residues on the Catalytic Domain of Factor XIa

Structural and Functional Significance of Amino Acid Lysine192 (chymotrypsin numbering) in Factor XIa and Factor VIIa.

Factor XI Contributes to Thrombin Generation in the Absence of Factor XIIa

Independence of Factor XIa Subunits in Factor IX Activation.

Dominant factor XI deficiency caused by mutations in the factor XI catalytic domain

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American Society of Hematology

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American Society of Hematology

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