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Li Tan, PhD
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Journal Articles

A Novel HCK Inhibitor Kin-8193 Blocks BTK Activity in BTK Cys481 Mutated Ibrutinib Resistant B-Cell Lymphomas Driven By Mutated MYD88

Guang Yang, PhD, Jinhua Wang, PhD, Li Tan, PhD, Xia Liu, MD, Manit Munshi, MS, Jiaji G Chen, Lian Xu, MS, Nickolas Tsakmaklis, Maria Demos, Amanda Kofides, Maria Luisa Guerrera, MD, Gloria G Chan, MS, Zachary R Hunter, PhD, Christopher Patterson, MAcc, Jorge J. Castillo, MD, Sara J Buhrlage, PhD, Nathanael S. Gray, PhD, Steven P Treon, MD PhD FRCP
Journal: Blood
Blood (2018) 132 (Supplement 1): 40.
https://doi.org/10.1182/blood-2018-99-119171
Published: 2018
Journal Articles

A Unique N-Phenylbenzamide Inhibitor Targeting Non-Receptor Tyrosine Kinases Potently Suppresses AML Cell Growth In Vitro and In Vivo

Mark C Weir, PhD, Sherry Shu, PhD, Sabine Hellwig, PhD, Ravi Patel, Li Chen, PhD, Li Tan, PhD, Nathanael Gray, PhD, Thomas Smithgall, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3813.
https://doi.org/10.1182/blood.V130.Suppl_1.3813.3813
Published: 2017
Journal Articles

Targeting IRAK1/IRAK4 Signaling in Waldenstrom's Macroglobulinemia

Guang Yang, PhD, Xia Liu, MD, Jie Chen, PhD, Lian Xu, Nicholas Tsakmaklis, Jiaji Chen, Christopher J Patterson, MFA, Jorge J Castillo, MD, Philip Cohen, Li Tan, PhD, Sara Buhrlage, PhD, Nathanael Gray, PhD, Steven P Treon, MD PhD
Journal: Blood
Blood (2015) 126 (23): 4004.
https://doi.org/10.1182/blood.V126.23.4004.4004
Published: 2015
Journal Articles

HCK Is a Highly Relevant Target of Ibrutinib in MYD88 Mutated Waldenstrom's Macroglobulinemia and Diffuse Large B-Cell Lymphoma

Guang Yang, PhD, Sara Buhrlage, PhD, Li Tan, PhD, Xia Liu, MD, Jie Chen, PhD, Zachary Hunter, PhD, Lian Xu, Nicholas Tsakmaklis, Jiaji Chen, Christopher J Patterson, MFA, Jorge J Castillo, MD, Wei Zhang, PhD, Nathanael Gray, PhD, Steven P Treon, MD PhD
Journal: Blood
Blood (2015) 126 (23): 705.
https://doi.org/10.1182/blood.V126.23.705.705
Published: 2015
Journal Articles

Germinal Center Kinase Regulates The Proliferation and Survival Of Diffuse Large B-Cell Lymphoma

Julie Marie Matthews, PhD, Li Tan, PhD, Shruti Bhatt, MS, Matthew Patricelli, PhD, Tyzoon Nomanbhoy, PhD, Jianming Zhang, PhD, Xiaoyu Jiang, PhD, Yasodha Natkunam, MD, PhD, Hwan Geun Choi, PhD, Andrew J. Gentles, PhD, Ezequiel Martinez, MS, Daxing Zhu, MD, Jennifer Rose Chapman, MD, Ragini M Shyam, MD, Shideh Chinichian, MD, Ranjana H. Advani, MD, Sara Buhrlage, Ph.D, Dita Gratzinger, MD, PhD, Nathanael S Gray, PhD, Izidore S Lossos, MD
Journal: Blood
Blood (2013) 122 (21): 643.
https://doi.org/10.1182/blood.V122.21.643.643
Published: 2013