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Journal Articles

Disruption of dNTP homeostasis by ribonucleotide reductase hyperactivation overcomes AML differentiation blockade

Hanying Wang, Xin He, Lei Zhang, Haojie Dong, Feiteng Huang, Jie Xian, Min Li, Wei Chen, Xiyuan Lu, Khyatiben V. Pathak, Wenfeng Huang, Zheng Li, Lianjun Zhang, Le Xuan Truong Nguyen, Lu Yang, Lifeng Feng, David J. Gordon, Jing Zhang, Patrick Pirrotte, Chun-Wei Chen, Amandeep Salhotra, Ya-Huei Kuo, David Horne, Guido Marcucci, David B. Sykes, Stefano Tiziani, Hongchuan Jin, Xian Wang, Ling Li
Journal: Blood
Blood (2022) 139 (26): 3752–3770.
DOI: https://doi.org/10.1182/blood.2021015108
Published: 2022
Includes: Supplemental data
Journal Articles

A Single-Arm, Open-Label, Pilot Trial of Autologous CD7-CAR-T Cells for CD7 Positive Relapsed and Refractory T-Lymphoblastic Leukemia/Lymphoma

Mingzhi Zhang, Xiaorui Fu, Huimin Meng, Min Wang, Yu Wang, Lei Zhang, Ling Li, Xin Li, Xinhua Wang, Zhenchang Sun, Hui Yu, Zhaoming Li, Feifei Nan, Yu Chang, Zhiyuan Zhou, Jiaqin Yan, Jiwei Li, Xiaolong Wu, Guifang Pan, Yanmei Zhao, Yu-Sheng Chen, Fengtao You, Lin Yang
Journal: Blood
Blood (2021) 138 (Supplement 1): 3829.
DOI: https://doi.org/10.1182/blood-2021-149999
Published: 2021
Journal Articles

The Impact of the Immunophenotyping Characteristics of Patients' Peripheral Blood on the Manufacturing and Clinical Outcome of CD7-Targeted Chimeric Antigen Receptor T Cells

Mingzhi Zhang, Xiaorui Fu, Huimin Meng, Min Wang, Yu Wang, Guifang Pan, Lei Zhang, Ling Li, Xin Li, Xinhua Wang, Zhenchang Sun, Hui Yu, Zhaoming Li, Feifei Nan, Yu Chang, Zhiyuan Zhou, Jiaqin Yan, Jiwei Li, Xiaolong Wu, Yanmei Zhao, Yu-Sheng Chen, Fengtao You, Dan Chen, Tingting Zhang, Bozhen Zhang, Lin Yang
Journal: Blood
Blood (2021) 138 (Supplement 1): 3830.
DOI: https://doi.org/10.1182/blood-2021-147632
Published: 2021
Journal Articles

The Design of a Phase 2 Study to Evaluate the Safety and Efficacy of Ropeginterferon Alfa-2b (P1101) in Chinese Patients with Polycythemia Vera Resistant or Intolerant to Hydroxyurea (HU)

Jie Jin, Lei Zhang, Su-Jiang Zhang, Suning Chen, Ming-hui Duan, Jingjing Zhang, Wei Wang, Warren Shen, Oleh Zagrijtschuk, Raymond Urbanski, Albert Qin, Zhijian Xiao
Journal: Blood
Blood (2021) 138 (Supplement 1): 4628.
DOI: https://doi.org/10.1182/blood-2021-146449
Published: 2021
Journal Articles

Ripk3 Signaling Restricts the Development of Peripheral T Cell Lymphoma in Tet2 Deficient Mice

Kanak Joshi, Ryan Mack, Lei Zhang, Shanhui Liu, Mark Sellin, Wei Wei, Peter Breslin, Ameet R Kini, Jiwang Zhang
Journal: Blood
Blood (2021) 138 (Supplement 1): 3318.
DOI: https://doi.org/10.1182/blood-2021-147896
Published: 2021
Journal Articles

Anti-PD-1-Antibody (Tislelizumab) Combined with Deacetylase Inhibitor (Chidamide), Lenalidomide and Etoposide for the Treatment of Refractory/Relapsed Extranodal Natural Killer/T Cell Lymphoma, Nasal Type (r/r-ENKTL): Preliminary Results from a Prospective, Multicenter, Single -Arm, Phase II Trial

Lei Zhang, Xiyang Liu, Xinhua Wang, Yu Chang, Xiaorui Fu, Xin Li, Ling Li, Jiaqin Yan, Feifei Nan, Xiaolong Wu, Linan Zhu, Zhenchang Sun, Hui Yu, Mingzhi Zhang
Journal: Blood
Blood (2021) 138 (Supplement 1): 1368.
DOI: https://doi.org/10.1182/blood-2021-152020
Published: 2021
Journal Articles

Identification of Pre-Gmps and Pre-Meps: Two Novel Types of Committed Progenitor Cells in Bone Marrow

Ryan Mack, Lei Zhang, Kanak Joshi, Shanhui Liu, Mark Sellin, Wei Wei, Peter Breslin, Jiwang Zhang
Journal: Blood
Blood (2021) 138 (Supplement 1): 3266.
DOI: https://doi.org/10.1182/blood-2021-153800
Published: 2021
Journal Articles

Targeting PRMT9 Suppresses Acute Myeloid Leukemia Maintenance

Haojie Dong, Xin He, Lei Zhang, Wei Chen, Yuhui Wu, Yinghui Zhu, Hanying Wang, Wenfeng Huang, Yichun Lin, Lianjun Zhang, Dandan Zhao, Juan Du, Rui Su, Ya-Huei Kuo, Jianjun Chen, Amandeep Salhotra, Guido Marcucci, Yun Luo, Ling Li
Journal: Blood
Blood (2021) 138 (Supplement 1): 358.
DOI: https://doi.org/10.1182/blood-2021-151679
Published: 2021
Journal Articles

Fotemustine-Based in Combination with Rituximab As First-Line Induction Chemotherapy for Newly Diagnosed Primary Central Nervous System Lymphoma:a Prospective Phaseii Trial

Jingjing Wu, Fenghua Gao, Lei Zhang, Xin Li, Ling Li, Xinhua Wang, Linan Zhu, Xudong Zhang, Xiaorui Fu, Zhenchang Sun, MD, PhD, Meng Dong, Mengjie Ding, Hui Yu, Feifei Nan, Jiaqin Yan, Yu Chang, Xiaolong Wu, Zhiyuan Zhou, Mingzhi Zhang, MD, Ken H. Young
Journal: Blood
Blood (2020) 136 (Supplement 1): 5.
DOI: https://doi.org/10.1182/blood-2020-137449
Published: 2020
Journal Articles

Repurposing Nelarabine to Induce Differentiation of Acute Myeloid Leukemia

Hanying Wang, Xin He, MD, Feiteng Huang, MS, Haojie Dong, PhD, Wei Chen, PhD, Zheng Li, MS, Jie Sun, PhD, Yinghui Zhu, PhD, Lei Zhang, MD, Yuhui Wu, MD, Lifeng Feng, PhD, Jing Zhang, PhD, Samer Khaled, MD, Guido Marcucci, MD, David Sykes, MD PhD, Hongchuan Jin, MD PhD, Xian Wang, MD PhD, Ling Li, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 26.
DOI: https://doi.org/10.1182/blood-2020-139922
Published: 2020
Journal Articles

The role of AGK in thrombocytopoiesis and possible therapeutic strategies

Haojie Jiang, Zhuo Yu, Nan Ding, Mina Yang, Lin Zhang, Xuemei Fan, Yuan Zhou, Qiang Zou, Jian Hou, Junke Zheng, Lei Zhang, Yanyan Xu, Junling Liu
Journal: Blood
Blood (2020) 136 (1): 119–129.
DOI: https://doi.org/10.1182/blood.2019003851
Published: 2020
Includes: Supplemental data
Journal Articles

Myc-Miz1 signaling promotes self-renewal of leukemia stem cells by repressing Cebpα and Cebpδ

Lei Zhang, Jing Li, Hui Xu, Xianyu Shao, Li Fu, Ye Hou, Caiqing Hao, Wenyan Li, Kanak Joshi, Wei Wei, Yan Xu, Feng Zhang, Shaojun Dai, Peter Breslin, Jiwang Zhang, Jun Zhang
Journal: Blood
Blood (2020) 135 (14): 1133–1145.
DOI: https://doi.org/10.1182/blood.2019001863
Published: 2020
Includes: Supplemental data
Journal Articles

Prognostic Value of Total Metabolic Tumor Volume and Total Lesion Glycolysis Measured By 18F-FDG PET-CT in Patients with T-Cell Lymphoblastic Lymphoma

Xiaoyan Feng, Xin Wen, Ling Li, Xin Li, Sun Zhenchang, Lei Zhang, Lugui Qiu, MD PhD, Mingzhi Zhang, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2851.
DOI: https://doi.org/10.1182/blood-2019-130091
Published: 2019
Journal Articles

Engine: Phase III Randomized Study of Enzastaurin/R-CHOP Versus Placebo/R-CHOP in Frontline High Risk Diffuse Large B Cell Lymphoma Patients with Novel Genomic Biomarker DGM1

Jun Zhu, MD PhD, Grzegorz Nowakowski, MD, Qingyuan Zhang, Joshua Brody, MD, Xiuhua Sun, MD, Joseph Maly, MD, Yuqin Song, MD PhD, Yongping Song, MD PhD, Jennifer Kimberly Lue, MD, Wen Luo, PhD, Lei Zhang, MD, Isabel Han, Manoj Jivani, Young Liu, Ling Li, MD, Joan Sun, MBA, Stephen D. Smith, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5330.
DOI: https://doi.org/10.1182/blood-2019-124930
Published: 2019
Journal Articles

Efficacy and Survival in Newly Diagnosed Advanced Extranodal Natural Killer/T-Cell Lymphoma: A Randomized, Controlled, Multicenter and Open-Labled Study with Ddgp Regimen Versus SMILE Regimen

Xinhua Wang, MD PhD, Lei Zhang, Xiangli Liu, Xin Li, Ling Li, Xiaorui Fu, Zhenchang Sun, Jingjing Wu, Xudong Zhang, Jiaqin Yan, Yu Chang, Feifei Nan, Zhiyuan Zhou, Xiaolong Wu, Li Tian, Wencai Li, Hongwei Xue, Jinghua Wang, Liqun Zou, Liping Su, Yi Lu, Yanzhen Guo, Ken H. Young, Mingzhi Zhang
Journal: Blood
Blood (2019) 134 (Supplement_1): 463.
DOI: https://doi.org/10.1182/blood-2019-127811
Published: 2019
Journal Articles

The Study of Thrombosis in JAK2 V617F Mutated Myeloproliferative Neoplasms

Jie Bai, MD, Yuhui Zhang, Yingshao Wang, Guangshuai Teng, Yan Wang, Chenxiao Du, Yafang Chen, Huiqin Zhang, Yanqi Li, Lixia Fu, Lei Zhang, MD, Yuan Zhou, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1149.
DOI: https://doi.org/10.1182/blood-2019-125429
Published: 2019
Journal Articles

Characterization of Methylation Patterns in Diffuse Large B Cell Lymphoma By Genome-Wide Methylation Analysis

Fengyi Zhao, M.M., Lei Zhang, M.M., Yan Qin, MD, Ming-Zhe Han, MD, Xiaohong Han, MD, Shiyu Jiang, M.M., Yuankai Shi, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1243.
DOI: https://doi.org/10.1182/blood-2019-131656
Published: 2019
Journal Articles

Efficacy and Safety of Apatinib in Relapsed or Refractory Diffuse Large B Cell Lymphoma: An Open-Label, Single-Arm, Prospective Study

Xinran Ma, MSc, Ling Li, Lei Zhang, Xin Li, Xiaorui Fu, Xinhua Wang, PhD, Jingjing Wu, Xudong Zhang, Xiaoyan Feng, Zhiyuan Zhou, Yu Chang, Zhaoming Li, MD PhD, Ken H. Young, Mingzhi Zhang
Journal: Blood
Blood (2019) 134 (Supplement_1): 2873.
DOI: https://doi.org/10.1182/blood-2019-127912
Published: 2019
Journal Articles

Ripk3 Signaling Regulates Hematopoietic Stem Cell Number and Function during Stress

Lei Zhang, PhD, Huacheng Luo, PhD, Jing Li, Hong-Min Ni, Mark Sellin, Feng Zhang, Jun Zhang, Peter Breslin, PhD, Wei Wei, William Small, Jr., Wen-Xin Ding, Suming Huang, PhD, Jiwang Zhang, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3714.
DOI: https://doi.org/10.1182/blood-2019-131332
Published: 2019
Journal Articles

The Splicing Modulator GEX1A Exhibits Potent Anti-Leukemic Activity Both in Vitro and In Vivo through Inducing an MCL1 Splice-Switch in Pre-Clinical Models of Acute Myeloid Leukemia

Mark Sellin, Ryan Mack, Matthew C. Rhodes, Lei Zhang, PhD, Wei Wei, Peter Breslin, PhD, Stephanie Berg, DO, Suming Huang, PhD, Richard Taylor, PhD, Jiwang Zhang, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2666.
DOI: https://doi.org/10.1182/blood-2019-132030
Published: 2019