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Klaus Dembowsky
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Journal Articles

Continuous blockade of CXCR4 results in dramatic mobilization and expansion of hematopoietic stem and progenitor cells

Darja Karpova, Julie K. Ritchey, Matthew S. Holt, Grazia Abou-Ezzi, Darlene Monlish, Lena Batoon, Susan Millard, Gabriele Spohn, Eliza Wiercinska, Ezhil Chendamarai, Wei Yang, Stephanie Christ, Leah Gehrs, Laura G. Schuettpelz, Klaus Dembowsky, Allison R. Pettit, Michael P. Rettig, Halvard Bonig, John F. DiPersio
Journal: Blood
Blood (2017) 129 (21): 2939–2949.
https://doi.org/10.1182/blood-2016-10-746909
Published: 2017
Includes: Supplemental data
Journal Articles

Potent Stem Cell Mobilization with the Novel CXCR4 Antagonist POL6326 - Results of a Phase IIa Dose Escalation Study in Comparison to G-CSF

Darja Karpova, PhD, Susanne Brauninger, MD, Eliza Wiercinska, PhD, Ariane Kraemer, B.Sc., Belinda Stock, Jochen Graff, MD, Christophe Escot, Garry Douglas, PhD, Barbara Romagnoli, PhD, Eric Chevalier, PhD, Klaus Dembowsky, MD PhD, Leon Hooftman, MD, Halvard Bonig, MD MA
Journal: Blood
Blood (2015) 126 (23): 511.
https://doi.org/10.1182/blood.V126.23.511.511
Published: 2015
Journal Articles

The Novel CXCR4 Antagonist POL5551 Decreases Surface CXCR4 (s-CXCR4) Expression, Inhibits Chemotaxis, and Enhances Chemosensitivity in Acute Lymphoblastic Leukemia (ALL)

Edward Allan R. Sison, MD, Daniel Magoon, Eric Chevalier, PhD, Klaus Dembowsky, MD, PhD, Patrick Brown, MD
Journal: Blood
Blood (2012) 120 (21): 780.
https://doi.org/10.1182/blood.V120.21.780.780
Published: 2012
Journal Articles

Targeting CXCR4, SDF1 and Beta-Adrenergic Receptors In the AML Microenvironment by Novel Antagonist POL6326, G-CSF and Isoproterenol

Ye Chen, PhD, Zhihong Zeng, PhD, Yuexi Shi, PhD, Rodrigo Jacamo, PhD, Christian Ludin, PhD, Klaus Dembowsky, PhD, Paul S. Frenette, MD, FRCPC, Marina Konopleva, MD, PhD, Michael Andreeff, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 2179.
https://doi.org/10.1182/blood.V116.21.2179.2179
Published: 2010
Journal Articles

First Results of a Phase-II Study with the New CXCR4 Antagonist POL6326 to Mobilize Hematopoietic Stem Cells (HSC) In Multiple Myeloma (MM)

Stefan Schmitt, Niels Weinhold, Klaus Dembowsky, Kai Neben, Mathias Witzens-Harig, Manfred Braun, Jennifer Klemmer, Patrick Wuchter, Christian Ludin, Anthony D. Ho, Hartmut Goldschmidt
Journal: Blood
Blood (2010) 116 (21): 824.
https://doi.org/10.1182/blood.V116.21.824.824
Published: 2010